Effects of COX inhibition on experimental pain and hyperalgesia during and after remifentanil infusion in humans

Pain

Volumn 152, Issue 6, 2011, Pages 1289-1297

  Lenz, Harald ^a   Raeder, Johan ^a   Draegni, Tomas ^a   Heyerdahl, Fridtjof ^a   Schmelz, Martin ^b   Stubhaug, Audun ^c  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Cold pressor test; Electrical pain model; Ketorolac; Opioid induced hyperalgesia; Parecoxib; Remifentanil

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; KETOROLAC; PARECOXIB; PLACEBO; REMIFENTANIL; SODIUM CHLORIDE;

ARTICLE; COLD PRESSOR TEST; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIZZINESS; DOUBLE BLIND PROCEDURE; ELECTROSTIMULATION; ENZYME INHIBITION; HUMAN; HYPERALGESIA; MALE; NAUSEA; NOCICEPTION; OPIOID INDUCED HYPERALGESIA; OPIOID NDUCED HYPERALGESIA; PAIN; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SEDATION; SIDE EFFECT; SINGLE BLIND PROCEDURE; TRANSCUTANEOUS NERVE STIMULATION;

ADULT; ANALGESICS, OPIOID; BLOOD PRESSURE; CYCLOOXYGENASE INHIBITORS; DRUG INTERACTIONS; HUMANS; HYPERALGESIA; ISOXAZOLES; KETOROLAC; MALE; MIDDLE AGED; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PHYSICAL STIMULATION; PIPERIDINES; TIME FACTORS; YOUNG ADULT;

EID: 79956123741     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2011.02.007     Document Type: Article

References (60)

1. M.S. Angst, and D.J. Clark Opioid-induced hyperalgesia: a qualitative systematic review Anesthesiology 104 2006 570 587
2. M.S. Angst, W. Koppert, I. Pahl, J.D. Clark, and M. Schmelz Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal Pain 106 2003 49 57 (Pubitemid 37329613)
3. S.F. Barton, F.F. Langeland, M.C. Snabes, D. LeComte, M.E. Kuss, S.S. Dhadda, and R.C. Hubbard Efficacy and safety of intravenous parecoxib sodium in relieving acute postoperative pain following gynecologic laparotomy surgery Anesthesiology 97 2002 306 314 (Pubitemid 34847740)
4. P. Bezzi, G. Carmignoto, L. Pasti, S. Vesce, D. Rossi, B.L. Rizzini, T. Pozzan, and A. Volterra Prostaglandins stimulate calcium-dependent glutamate release in astrocytes Nature 391 1998 281 285 (Pubitemid 28099014)
5. G.B. Bikhazi, M.C. Snabes, Z.H. Bajwa, D.J. Davis, D. LeComte, L. Traylor, and R.C. Hubbard A clinical trial demonstrates the analgesic activity of intravenous parecoxib sodium compared with ketorolac or morphine after gynecologic surgery with laparotomy Am J Obstet Gynecol 191 2004 1183 1191 (Pubitemid 39421569)
6. H. Brown, and R. Prescott Advantages of mixed models in cross-over trials V. Barnett, Statistics in practice: applied mixed models in medicine 1999 Wiley Indianapolis, IN 261 262
7. A. Buvanendran, J.S. Kroin, R.A. Berger, N.J. Hallab, C. Saha, C. Negrescu, M. Moric, M.S. Caicedo, and K.J. Tuman Upregulation of prostaglandin E2 and interleukins in the central nervous system and peripheral tissue during and after surgery in humans Anesthesiology 104 2006 403 410
8. E. Celerier, C. Rivat, Y. Jun, J.P. Laulin, A. Larcher, P. Reynier, and G. Simonnet Long-lasting hyperalgesia induced by fentanyl in rats: preventive effect of ketamine Anesthesiology 92 2000 465 472 (Pubitemid 30078345)
9. S.M. Cheer, and K.L. Goa Parecoxib (parecoxib sodium) Drugs 61 2001 1133 1141 (Pubitemid 32661226)
10. L. Chen, C. Malarick, L. Seefeld, S. Wang, M. Houghton, and J. Mao Altered quantitative sensory testing outcome in subjects with opioid therapy Pain 143 2009 65 70
11. Y.Y. Chia, K. Liu, J.J. Wang, M.C. Kuo, and S.T. Ho Intraoperative high dose fentanyl induces postoperative fentanyl tolerance Can J Anaesth 46 1999 872 877 (Pubitemid 29528851)
12. L.F. Chu, M.S. Angst, and D.J. Clark Opioid-induced hyperalgesia in humans: molecular mechanisms and clinical considerations Clin J Pain 24 2008 479 496
13. L.F. Chu, D.J. Clark, and M.S. Angst Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: a preliminary prospective study J Pain 7 2006 43 48 (Pubitemid 43097262)
14. L.F. Chu, J. Dairmont, A.K. Zamora, C.A. Young, and M.S. Angst The endogenous opioid system is not involved in modulation of opioid-induced hyperalgesia J Pain 12 2011 108 115
15. P. Compton, P. Athanasos, and D. Elashoff Withdrawal hyperalgesia after acute opioid physical dependence in nonaddicted humans: a preliminary study J Pain 4 2003 511 519 (Pubitemid 37541795)
16. R. Drdla, M. Gassner, E. Gingl, and J. Sandkuhler Induction of synaptic long-term potentiation after opioid withdrawal Science 325 2009 207 210
17. M. Dusch, B. Namer, M. Strupf, M. Schley, R. Rukwied, B. Hägglöf, M. Schmelz, and W. Koppert Cross-over evaluation of electrically induced pain and hyperalgesia Scand J Pain 4 2010 205 210
18. A. Ebersberger, B.D. Grubb, H.L. Willingale, N.J. Gardiner, J. Nebe, and H.G. Schaible The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an up-regulation of cyclo-oxygenase-2 in the spinal cord Neuroscience 93 1999 775 781 (Pubitemid 29329481)
19. K. Eckhardt, S. Ammon, U. Hofmann, A. Riebe, N. Gugeler, and G. Mikus Gabapentin enhances the analgesic effect of morphine in healthy volunteers Anesth Analg 91 2000 185 191 (Pubitemid 30437084)
20. S.H. Ferreira, F.Q. Cunha, B.B. Lorenzetti, M.A. Michelin, M. Perretti, R.J. Flower, and S. Poole Role of lipocortin-1 in the anti-hyperalgesic actions of dexamethasone Br J Pharmacol 121 1997 883 888 (Pubitemid 27277781)
21. B. Guignard, A.E. Bossard, C. Coste, D.I. Sessler, C. Lebrault, P. Alfonsi, D. Fletcher, and M. Chauvin Acute opioid tolerance: intraoperative remifentanil increases postoperative pain and morphine requirement Anesthesiology 93 2000 409 417 (Pubitemid 30620314)
22. E.G. Hansen, T.H. Duedahl, J. Romsing, K.L. Hilsted, and J.B. Dahl Intra-operative remifentanil might influence pain levels in the immediate post-operative period after major abdominal surgery Acta Anaesthesiol Scand 49 2005 1464 1470 (Pubitemid 41565027)
23. Y. Hochberg, and A.C. Tamhane Multiple comparison procedures 1990 Wiley New York
24. V. Joly, P. Richebe, B. Guignard, D. Fletcher, P. Maurette, D.I. Sessler, and M. Chauvin Remifentanil-induced postoperative hyperalgesia and its prevention with small-dose ketamine Anesthesiology 103 2005 147 155 (Pubitemid 40943147)
25. W. Klement, and J.O. Arndt The role of nociceptors of cutaneous veins in the mediation of cold pain in man J Physiol 449 1992 73 83
26. W. Koppert, M.S. Angst, M. Alsheimer, R. Sittl, S. Albrecht, J. Schuttler, and M. Schmelz Naloxone provokes similar pain facilitation as observed after short-term infusion of remifentanil in humans Pain 106 2003 91 99 (Pubitemid 37329618)
27. W. Koppert, S.K. Dern, R. Sittl, S. Albrecht, J. Schuttler, and M. Schmelz A new model of electrically evoked pain and hyperalgesia in human skin: the effects of intravenous alfentanil, S(+)-ketamine, and lidocaine Anesthesiology 95 2001 395 402 (Pubitemid 32720728)
28. W. Koppert, J. Filitz, A. Troster, H. Ihmsen, M. Angst, H. Flor, J. Schuttler, and M. Schmelz Activation of naloxone-sensitive and -insensitive inhibitory systems in a human pain model J Pain 6 2005 757 764 (Pubitemid 41579073)
29. W. Koppert, R. Sittl, K. Scheuber, M. Alsheimer, M. Schmelz, and J. Schuttler Differential modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by S-ketamine and clonidine in humans Anesthesiology 99 2003 152 159 (Pubitemid 36799046)
30. R.C. Littell, J. Pendergast, and R. Natarajan Modelling covariance structure in the analysis of repeated measures data Stat Med 19 2000 1793 1819 (Pubitemid 30436064)
31. M. Luginbuhl, A. Gerber, T.W. Schnider, S. Petersen-Felix, L. Arendt-Nielsen, and M. Curatolo Modulation of remifentanil-induced analgesia, hyperalgesia, and tolerance by small-dose ketamine in humans Anesth Analg 96 2003 726 732 (Pubitemid 36245560)
32. W. Magerl, P.N. Fuchs, R.A. Meyer, and R.D. Treede Roles of capsaicin-insensitive nociceptors in cutaneous pain and secondary hyperalgesia Brain 124 2001 1754 1764 (Pubitemid 32845437)
33. A.B. Malmberg, and T.L. Yaksh Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition Science 257 1992 1276 1279
34. A.B. Malmberg, and T.L. Yaksh Spinal actions of non-steroidal anti-inflammatory drugs: evidence for a central role of prostanoids in nociceptive processing Prog Pharmacol Clin Pharmacol 10 1993 91 110 (Pubitemid 23217770)
35. C.F. Minto, T.W. Schnider, T.D. Egan, E. Youngs, H.J. Lemmens, P.L. Gambus, V. Billard, J.F. Hoke, K.H. Moore, D.J. Hermann, K.T. Muir, J.W. Mandema, and S.L. Shafer Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development Anesthesiology 86 1997 10 23 (Pubitemid 27043998)
36. C.F. Minto, T.W. Schnider, and S.L. Shafer Pharmacokinetics and pharmacodynamics of remifentanil II. Model application. Anesthesiology 86 1997 24 33
37. J.S. Mogil, S.G. Wilson, K. Bon, S.E. Lee, K. Chung, P. Raber, J.O. Pieper, H.S. Hain, J.K. Belknap, L. Hubert, G.I. Elmer, J.M. Chung, and M. Devor Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception Pain 80 1999 67 82 (Pubitemid 29151691)
38. D.D. O'Rielly, and C.W. Loomis Increased expression of cyclooxygenase and nitric oxide isoforms, and exaggerated sensitivity to prostaglandin E2, in the rat lumbar spinal cord 3 days after L5-L6 spinal nerve ligation Anesthesiology 104 2006 328 337
39. D. Pud, Y. Granovsky, and D. Yarnitsky The methodology of experimentally induced diffuse noxious inhibitory control (DNIC)-like effect in humans Pain 144 2009 16 19
40. G.L. Rasmussen, K. Steckner, C. Hogue, S. Torri, and R.C. Hubbard Intravenous parecoxib sodium for acute pain after orthopedic knee surgery Am J Orthop 31 2002 336 343
41. C. Rivat, J.P. Laulin, J.B. Corcuff, E. Celerier, L. Pain, and G. Simonnet Fentanyl enhancement of carrageenan-induced long-lasting hyperalgesia in rats: prevention by the N-methyl-d-aspartate receptor antagonist ketamine Anesthesiology 96 2002 381 391 (Pubitemid 34121749)
42. J. Romsing, and S. Moiniche A systematic review of COX-2 inhibitors compared with traditional NSAIDs, or different COX-2 inhibitors for post-operative pain Acta Anaesthesiol Scand 48 2004 525 546 (Pubitemid 38649583)
43. R.P. Schleimer An overview of glucocorticoid anti-inflammatory actions Eur J Clin Pharmacol 45 Suppl 1 1993 3 7
44. M. Schmelz, R. Schmidt, H.O. Handwerker, and H.E. Torebjork Encoding of burning pain from capsaicin-treated human skin in two categories of unmyelinated nerve fibres Brain 123 2000 560 571 (Pubitemid 30099540)
45. G.W. Snedecor, and W.G. Cochran Statistical methods 7th ed. 1980 Iowa State University Press Ames, IA
46. M.D. Southall, R.L. Michael, and M.R. Vasko Intrathecal NSAIDS attenuate inflammation-induced neuropeptide release from rat spinal cord slices Pain 78 1998 39 48 (Pubitemid 28451527)
47. A. Stubhaug, L. Romundstad, T. Kaasa, and H. Breivik Methylprednisolone and ketorolac rapidly reduce hyperalgesia around a skin burn injury and increase pressure pain thresholds Acta Anaesthesiol Scand 51 2007 1138 1146 (Pubitemid 47389685)
48. C.I. Svensson, and T.L. Yaksh The spinal phospholipase-cyclooxygenase- prostanoid cascade in nociceptive processing Annu Rev Pharmacol 42 2002 553 583 (Pubitemid 34162547)
49. J.J. Talley, S.R. Bertenshaw, D.L. Brown, J.S. Carter, M.J. Graneto, M.S. Kellogg, C.M. Koboldt, J. Yuan, Y.Y. Zhang, and K. Seibert N-[[(5-methyl-3- phenylisoxazol-4-yl)-phenyl]sulfonyl]propanamide, sodium salt, parecoxib sodium: a potent and selective inhibitor of COX-2 for parenteral administration J Med Chem 43 2000 1661 1663 (Pubitemid 30304998)
50. A. Tröster, R. Sittl, B. Singler, M. Schmelz, J. Schuttler, and W. Koppert Modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by parecoxib in humans Anesthesiology 105 2006 1016 1023 (Pubitemid 44655514)
51. G. Verbeke, and G. Molenberghs Linear mixed models in practice: a SAS-oriented approach G. Verbeke, G. Molenberghs, Lecture notes in statistics 1997 Springer-Verlag New York 2 27
52. T.D. Warner, F. Giuliano, I. Vojnovic, A. Bukasa, J.A. Mitchell, and J.R. Vane Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis Proc Natl Acad Sci USA 96 1999 7563 7568 (Pubitemid 29299702)
53. L.D. Waterbury, D. Silliman, and T. Jolas Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium Curr Med Res Opin 22 2006 1133 1140 (Pubitemid 44000733)
54. C. Weidner, M. Schmelz, R. Schmidt, B. Hansson, H.O. Handwerker, and H.E. Torebjork Functional attributes discriminating mechano-insensitive and mechano-responsive C nociceptors in human skin J Neurosci 19 1999 10184 10190 (Pubitemid 30226690)
55. H.L. Willingale, N.J. Gardiner, N. McLymont, S. Giblett, and B.D. Grubb Prostanoids synthesized by cyclo-oxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability Br J Pharmacol 122 1997 1593 1604 (Pubitemid 28000185)
56. S. Wolff, and J.D. Hardy Studies on pain; observations on pain due to local cooling and on factors involved in the cold pressor effect J Clin Invest 20 1941 521 533
57. Y. Xuerong, H. Yuguang, J. Xia, and W. Hailan Ketamine and lornoxicam for preventing a fentanyl-induced increase in postoperative morphine requirement Anesth Analg 107 2008 2032 2037
58. T. Yamamoto, and N. Nozaki-Taguchi Role of spinal cyclooxygenase (COX)-2 on thermal hyperalgesia evoked by carageenan injection in the rat Neuroreport 8 1997 2179 2182 (Pubitemid 27319668)
59. X. Zhu, D.R. Conklin, and J.C. Eisenach Cyclooxygenase-1 in the spinal cord plays an important role in postoperative pain Pain 104 2003 15 23 (Pubitemid 36835870)
60. X. Zhu, D.R. Conklin, and J.C. Eisenach Preoperative inhibition of cyclooxygenase-1 in the spinal cord reduces postoperative pain Anesth Analg 100 2005 1390 1393 (Pubitemid 40577392)