메뉴 건너뛰기




Volumn 85, Issue 11, 2011, Pages 5581-5592

Transgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; VIRUS MIDDLE T ANTIGEN;

EID: 79956094293     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02609-10     Document Type: Article
Times cited : (7)

References (73)
  • 1
    • 0043244937 scopus 로고    scopus 로고
    • Nkx3. 1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases
    • Abate-Shen, C., et al. 2003. Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases. Cancer Res. 63:3886-3890.
    • (2003) Cancer Res. , vol.63 , pp. 3886-3890
    • Abate-Shen, C.1
  • 2
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill, F. 2004. Cancer and the chemokine network. Nat. Rev. Cancer 4:540-550.
    • (2004) Nat. Rev. Cancer. , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 3
    • 40149110221 scopus 로고    scopus 로고
    • CXCL5 promotes prostate cancer progression
    • Begley, L. A., et al. 2008. CXCL5 promotes prostate cancer progression. Neoplasia 10:244-254.
    • (2008) Neoplasia , vol.10 , pp. 244-254
    • Begley, L.A.1
  • 4
    • 40949144957 scopus 로고    scopus 로고
    • Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment
    • Bierie, B., et al. 2008. Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment. Cancer Res. 68:1809-1819.
    • (2008) Cancer Res. , vol.68 , pp. 1809-1819
    • Bierie, B.1
  • 5
    • 0028332032 scopus 로고
    • Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen
    • Campbell, K. S., et al. 1994. Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen. Proc. Natl. Acad. Sci. U. S. A. 91:6344-6348.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 6344-6348
    • Campbell, K.S.1
  • 6
    • 34249301737 scopus 로고    scopus 로고
    • ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo
    • Casimiro, M., et al. 2007. ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo. Cancer Res. 67:4364-4372.
    • (2007) Cancer Res. , vol.67 , pp. 4364-4372
    • Casimiro, M.1
  • 7
    • 30344432929 scopus 로고    scopus 로고
    • Differential sensitivity of mouse epithelial tissues to the polyomavirus middle T oncogene
    • Cecena, G., F. Wen, R. D. Cardiff, and R. G. Oshima. 2006. Differential sensitivity of mouse epithelial tissues to the polyomavirus middle T oncogene. Am. J. Pathol. 168:310-320.
    • (2006) Am. J. Pathol. , vol.168 , pp. 310-320
    • Cecena, G.1    Wen, F.2    Cardiff, R.D.3    Oshima, R.G.4
  • 8
    • 0032559272 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study
    • Chan, J. M., et al. 1998. Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science 279:563-566.
    • (1998) Science , vol.279 , pp. 563-566
    • Chan, J.M.1
  • 9
    • 23244460597 scopus 로고    scopus 로고
    • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
    • Chen, Z., et al. 2005. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436:725-730.
    • (2005) Nature , vol.436 , pp. 725-730
    • Chen, Z.1
  • 11
    • 0031870959 scopus 로고    scopus 로고
    • Pten is essential for embryonic development and tumour suppression
    • Di Cristofano, A., B. Pesce, C. Cordon-Cardo, and P. P. Pandolfi. 1998. Pten is essential for embryonic development and tumour suppression. Nat. Genet. 19:348-355.
    • (1998) Nat. Genet. , vol.19 , pp. 348-355
    • Di Cristofano, A.1    Pesce, B.2    Cordon-Cardo, C.3    Pandolfi, P.P.4
  • 12
    • 0028091333 scopus 로고
    • Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc
    • Dilworth, S. M., et al. 1994. Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc. Nature 367: 87-90.
    • (1994) Nature , vol.367 , pp. 87-90
    • Dilworth, S.M.1
  • 14
    • 0141569009 scopus 로고    scopus 로고
    • Myc-driven murine prostate cancer shares molecular features with human prostate tumors
    • Ellwood-Yen, K., et al. 2003. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell 4:223-238.
    • (2003) Cancer Cell , vol.4 , pp. 223-238
    • Ellwood-Yen, K.1
  • 15
    • 78449263437 scopus 로고    scopus 로고
    • Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice
    • Elo, T. D., et al. 2010. Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice. Neoplasia 12:915-927.
    • (2010) Neoplasia , vol.12 , pp. 915-927
    • Elo, T.D.1
  • 16
    • 76349096670 scopus 로고    scopus 로고
    • Cancerassociated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner
    • Erez, N., M. Truitt, P. Olson, S. T. Arron, and D. Hanahan. 2010. Cancerassociated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner. Cancer Cell 17:135-147.
    • (2010) Cancer Cell , vol.17 , pp. 135-147
    • Erez, N.1    Truitt, M.2    Olson, P.3    Arron, S.T.4    Hanahan, D.5
  • 17
    • 70349467638 scopus 로고    scopus 로고
    • Lessons in signaling and tumorigenesis from polyomavirus middle T antigen
    • Fluck, M. M., and B. S. Schaffhausen. 2009. Lessons in signaling and tumorigenesis from polyomavirus middle T antigen. Microbiol. Mol. Biol. Rev. 73:542-563.
    • (2009) Microbiol. Mol. Biol. Rev. , vol.73 , pp. 542-563
    • Fluck, M.M.1    Schaffhausen, B.S.2
  • 18
    • 0036568414 scopus 로고    scopus 로고
    • Independent prognostic significance of HER-2 oncoprotein expression in pN0 prostate cancer undergoing curative radiotherapy
    • Fossa, A., et al. 2002. Independent prognostic significance of HER-2 oncoprotein expression in pN0 prostate cancer undergoing curative radiotherapy. Int. J. Cancer 99:100-105.
    • (2002) Int. J. Cancer. , vol.99 , pp. 100-105
    • Fossa, A.1
  • 19
    • 0027053678 scopus 로고
    • Changes in frequency, morphology, and behavior of tumors induced in mice by a polyoma virus mutant with a specifically altered oncogene
    • Freund, R., C. J. Dawe, J. P. Carroll, and T. L. Benjamin. 1992. Changes in frequency, morphology, and behavior of tumors induced in mice by a polyoma virus mutant with a specifically altered oncogene. Am. J. Pathol. 141: 1409-1425.
    • (1992) Am. J. Pathol. , vol.141 , pp. 1409-1425
    • Freund, R.1    Dawe, C.J.2    Carroll, J.P.3    Benjamin, T.L.4
  • 21
  • 22
    • 0028911462 scopus 로고
    • Prostate cancer in a transgenic mouse
    • Greenberg, N. M., et al. 1995. Prostate cancer in a transgenic mouse. Proc. Natl. Acad. Sci. U. S. A. 92:3439-3443.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 3439-3443
    • Greenberg, N.M.1
  • 23
    • 0026587657 scopus 로고
    • Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease
    • Guy, C. T., R. D. Cardiff, and W. J. Muller. 1992. Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol. Cell. Biol. 12:954-961.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 954-961
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 24
    • 0036561908 scopus 로고    scopus 로고
    • Modelling the molecular circuitry of cancer
    • Hahn, W. C., and R. A. Weinberg. 2002. Modelling the molecular circuitry of cancer. Nat. Rev. Cancer. 2:331-341.
    • (2002) Nat. Rev. Cancer. , vol.2 , pp. 331-341
    • Hahn, W.C.1    Weinberg, R.A.2
  • 25
    • 51649111988 scopus 로고    scopus 로고
    • Gene expression profile of mouse prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer therapy
    • Haram, K. M., et al. 2008. Gene expression profile of mouse prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer therapy. Prostate 68:1517-1530.
    • (2008) Prostate , vol.68 , pp. 1517-1530
    • Haram, K.M.1
  • 26
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
    • Herschkowitz, J. I., et al. 2007. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol. 8:R76.
    • (2007) Genome Biol. , vol.8
    • Herschkowitz, J.I.1
  • 27
    • 49649087385 scopus 로고    scopus 로고
    • Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis
    • Jia, S., et al. 2008. Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis. Nature 454:776-779.
    • (2008) Nature , vol.454 , pp. 776-779
    • Jia, S.1
  • 29
    • 0011177709 scopus 로고
    • Phosphatidylinositol metabolism and polyomamediated transformation
    • Kaplan, D. R., et al. 1986. Phosphatidylinositol metabolism and polyomamediated transformation. Proc. Natl. Acad. Sci. U. S. A. 83:3624-3628.
    • (1986) Proc. Natl. Acad. Sci. U. S. A. , vol.83 , pp. 3624-3628
    • Kaplan, D.R.1
  • 30
    • 0036605972 scopus 로고    scopus 로고
    • Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis
    • Kim, M. J., et al. 2002. Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Res. 62:2999-3004.
    • (2002) Cancer Res. , vol.62 , pp. 2999-3004
    • Kim, M.J.1
  • 31
    • 0037022663 scopus 로고    scopus 로고
    • Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis
    • Kim, M. J., et al. 2002. Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Proc. Natl. Acad. Sci. U. S. A. 99:2884-2889.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 2884-2889
    • Kim, M.J.1
  • 32
    • 77954641960 scopus 로고    scopus 로고
    • A constitutively activated form of the p110beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice
    • Lee, S. H., et al. 2010. A constitutively activated form of the p110beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice. Proc. Natl. Acad. Sci. U. S. A. 107:11002-11007.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 11002-11007
    • Lee, S.H.1
  • 33
    • 0346731132 scopus 로고    scopus 로고
    • The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer
    • Lewis, B. C., D. S. Klimstra, and H. E. Varmus. 2003. The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer. Genes Dev. 17:3127-3138.
    • (2003) Genes Dev. , vol.17 , pp. 3127-3138
    • Lewis, B.C.1    Klimstra, D.S.2    Varmus, H.E.3
  • 34
    • 33646177968 scopus 로고    scopus 로고
    • Prostatic intraepithelial neoplasia and adenocarcinoma in mice expressing a probasin-Neu oncogenic transgene
    • Li, Z., M. Szabolcs, J. D. Terwilliger, and A. Efstratiadis. 2006. Prostatic intraepithelial neoplasia and adenocarcinoma in mice expressing a probasin-Neu oncogenic transgene. Carcinogenesis 27:1054-1067.
    • (2006) Carcinogenesis , vol.27 , pp. 1054-1067
    • Li, Z.1    Szabolcs, M.2    Terwilliger, J.D.3    Efstratiadis, A.4
  • 35
    • 0035911221 scopus 로고    scopus 로고
    • Colonystimulating factor 1 promotes progression of mammary tumors to malignancy
    • Lin, E. Y., A. V. Nguyen, R. G. Russell, and J. W. Pollard. 2001. Colonystimulating factor 1 promotes progression of mammary tumors to malignancy. J. Exp. Med. 193:727-740.
    • (2001) J. Exp. Med. , vol.193 , pp. 727-740
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4
  • 36
    • 42049095273 scopus 로고    scopus 로고
    • CXCL16 functions as a novel chemotactic factor for prostate cancer cells in vitro
    • Lu, Y., et al. 2008. CXCL16 functions as a novel chemotactic factor for prostate cancer cells in vitro. Mol. Cancer Res. 6:546-554.
    • (2008) Mol. Cancer Res. , vol.6 , pp. 546-554
    • Lu, Y.1
  • 37
    • 21344454216 scopus 로고    scopus 로고
    • Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis
    • Ma, X., et al. 2005. Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis. Cancer Res. 65:5730-5739.
    • (2005) Cancer Res. , vol.65 , pp. 5730-5739
    • Ma, X.1
  • 38
    • 4444238684 scopus 로고    scopus 로고
    • Polyomavirus middle T-induced mammary intraepithelial neoplasia outgrowths: single origin, divergent evolution, and multiple outcomes
    • Maglione, J. E., et al. 2004. Polyomavirus middle T-induced mammary intraepithelial neoplasia outgrowths: single origin, divergent evolution, and multiple outcomes. Mol. Cancer Ther. 3:941-953.
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 941-953
    • Maglione, J.E.1
  • 39
    • 2942724235 scopus 로고    scopus 로고
    • mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
    • Majumder, P. K., et al. 2004. mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. Nat. Med. 10:594-601.
    • (2004) Nat. Med. , vol.10 , pp. 594-601
    • Majumder, P.K.1
  • 40
    • 0038271762 scopus 로고    scopus 로고
    • Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model
    • Majumder, P. K., et al. 2003. Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model. Proc. Natl. Acad. Sci. U. S. A. 100:7841-7846.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 7841-7846
    • Majumder, P.K.1
  • 41
    • 0035266381 scopus 로고    scopus 로고
    • A probasin-large T antigen transgenic mouse line develops prostate adenocarcinoma and neuroendocrine carcinoma with metastatic potential
    • Masumori, N., et al. 2001. A probasin-large T antigen transgenic mouse line develops prostate adenocarcinoma and neuroendocrine carcinoma with metastatic potential. Cancer Res. 61:2239-2249.
    • (2001) Cancer Res , vol.61 , pp. 2239-2249
    • Masumori, N.1
  • 42
    • 0028170155 scopus 로고
    • Expression of p160erbB-3 and p185erbB-2 in prostatic intraepithelial neoplasia and prostatic adenocarcinoma
    • Myers, R. B., S. Srivastava, D. K. Oelschlager, and W. E. Grizzle. 1994. Expression of p160erbB-3 and p185erbB-2 in prostatic intraepithelial neoplasia and prostatic adenocarcinoma. J. Natl. Cancer Inst. 86:1140-1145.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1140-1145
    • Myers, R.B.1    Srivastava, S.2    Oelschlager, D.K.3    Grizzle, W.E.4
  • 43
    • 33846626476 scopus 로고    scopus 로고
    • Heterogeneity of mammary lesions represent molecular differences
    • Namba, R., et al. 2006. Heterogeneity of mammary lesions represent molecular differences. BMC Cancer 6:275.
    • (2006) BMC Cancer , vol.6 , pp. 275
    • Namba, R.1
  • 44
    • 27744600091 scopus 로고    scopus 로고
    • Serum levels of shed Her2/neu protein in men with prostate cancer correlate with disease progression
    • Osman, I., et al. 2005. Serum levels of shed Her2/neu protein in men with prostate cancer correlate with disease progression. J. Urol. 174:2174-2177.
    • (2005) J. Urol. , vol.174 , pp. 2174-2177
    • Osman, I.1
  • 45
    • 42049109923 scopus 로고    scopus 로고
    • Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer
    • Ouyang, X., et al. 2008. Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer. Cancer Res. 68: 2132-2144.
    • (2008) Cancer Res. , vol.68 , pp. 2132-2144
    • Ouyang, X.1
  • 46
    • 34447632167 scopus 로고    scopus 로고
    • Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two populationbased cohorts
    • Pawitan, Y., et al. 2005. Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two populationbased cohorts. Breast Cancer Res. 7:R953-R964.
    • (2005) Breast Cancer Res. , vol.7
    • Pawitan, Y.1
  • 47
    • 22844435223 scopus 로고    scopus 로고
    • Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas
    • Pedersen, T. X., et al. 2005. Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas. Carcinogenesis 26:1233-1240.
    • (2005) Carcinogenesis , vol.26 , pp. 1233-1240
    • Pedersen, T.X.1
  • 48
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl, M. W. 2001. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29:e45.
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 49
    • 4344688268 scopus 로고    scopus 로고
    • Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease
    • Qiu, T. H., et al. 2004. Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease. Cancer Res. 64:5973-5981.
    • (2004) Cancer Res. , vol.64 , pp. 5973-5981
    • Qiu, T.H.1
  • 51
    • 59449098593 scopus 로고    scopus 로고
    • Lessons from polyoma middle T antigen on signaling and transformation: a DNA tumor virus contribution to the war on cancer
    • Schaffhausen, B. S., and T. M. Roberts. 2009. Lessons from polyoma middle T antigen on signaling and transformation: a DNA tumor virus contribution to the war on cancer. Virology 384:304-316.
    • (2009) Virology , vol.384 , pp. 304-316
    • Schaffhausen, B.S.1    Roberts, T.M.2
  • 52
    • 2442653901 scopus 로고    scopus 로고
    • Prostatic intraepithelial neoplasia and intestinal metaplasia in prostates of probasin-RAS transgenic mice
    • Scherl, A., J. F. Li, R. D. Cardiff, and N. Schreiber-Agus. 2004. Prostatic intraepithelial neoplasia and intestinal metaplasia in prostates of probasin-RAS transgenic mice. Prostate 59:448-459.
    • (2004) Prostate , vol.59 , pp. 448-459
    • Scherl, A.1    Li, J.F.2    Cardiff, R.D.3    Schreiber-Agus, N.4
  • 53
    • 34248358157 scopus 로고    scopus 로고
    • PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors
    • Shepard, C. R., J. Kassis, D. L. Whaley, H. G. Kim, and A. Wells. 2007. PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors. Oncogene 26:3020-3026.
    • (2007) Oncogene , vol.26 , pp. 3020-3026
    • Shepard, C.R.1    Kassis, J.2    Whaley, D.L.3    Kim, H.G.4    Wells, A.5
  • 54
    • 0034614108 scopus 로고    scopus 로고
    • Her-2-neu expression and progression toward androgen independence in human prostate cancer
    • Signoretti, S., et al. 2000. Her-2-neu expression and progression toward androgen independence in human prostate cancer. J. Natl. Cancer Inst. 92:1918-1925.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1918-1925
    • Signoretti, S.1
  • 55
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
    • Smyth, G. K. 2004. Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl. Genet. Mol. Biol. 3:Article3.
    • (2004) Stat Appl. Genet. Mol. Biol. , vol.3
    • Smyth, G.K.1
  • 56
    • 0036733760 scopus 로고    scopus 로고
    • Fibroblast growth factor 8 isoform B overexpression in prostate epithelium: a new mouse model for prostatic intraepithelial neoplasia
    • Song, Z., et al. 2002. Fibroblast growth factor 8 isoform B overexpression in prostate epithelium: a new mouse model for prostatic intraepithelial neoplasia. Cancer Res. 62:5096-5105.
    • (2002) Cancer Res. , vol.62 , pp. 5096-5105
    • Song, Z.1
  • 57
    • 0028114305 scopus 로고
    • Polyomavirus middle-sized tumor antigen modulates c-Jun phosphorylation and transcriptional activity
    • Srinivas, S., A. Schonthal, and W. Eckhart. 1994. Polyomavirus middle-sized tumor antigen modulates c-Jun phosphorylation and transcriptional activity. Proc. Natl. Acad. Sci. U. S. A. 91:10064-10068.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 10064-10068
    • Srinivas, S.1    Schonthal, A.2    Eckhart, W.3
  • 58
    • 0029055747 scopus 로고
    • Association of polyomavirus middle tumor antigen with phospholipase C-gamma 1
    • Su, W., W. Liu, B. S. Schaffhausen, and T. M. Roberts. 1995. Association of polyomavirus middle tumor antigen with phospholipase C-gamma 1. J. Biol. Chem. 270:12331-12334.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12331-12334
    • Su, W.1    Liu, W.2    Schaffhausen, B.S.3    Roberts, T.M.4
  • 59
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: a knowledgebased approach for interpreting genome-wide expression profiles
    • Subramanian, A., et al. 2005. Gene set enrichment analysis: a knowledgebased approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. U. S. A. 102:15545-15550.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 60
    • 57149112529 scopus 로고    scopus 로고
    • Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis
    • Sung, S. Y., et al. 2008. Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis. Cancer Res. 68:9996-10003.
    • (2008) Cancer Res. , vol.68 , pp. 9996-10003
    • Sung, S.Y.1
  • 61
    • 0031964511 scopus 로고    scopus 로고
    • Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues
    • Suzuki, H., et al. 1998. Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues. Cancer Res. 58: 204-209.
    • (1998) Cancer Res. , vol.58 , pp. 204-209
    • Suzuki, H.1
  • 62
    • 0029794270 scopus 로고    scopus 로고
    • Neoplastic transformation of prostatic and urogenital epithelium by the polyoma virus middle T gene
    • Tehranian, A., et al. 1996. Neoplastic transformation of prostatic and urogenital epithelium by the polyoma virus middle T gene. Am. J. Pathol. 149:1177-1191.
    • (1996) Am. J. Pathol. , vol.149 , pp. 1177-1191
    • Tehranian, A.1
  • 63
    • 4243110417 scopus 로고    scopus 로고
    • Pten dose dictates cancer progression in the prostate
    • Trotman, L. C., et al. 2003. Pten dose dictates cancer progression in the prostate. PLoS Biol. 1:E59.
    • (2003) PLoS Biol. , vol.1
    • Trotman, L.C.1
  • 64
    • 0035170731 scopus 로고    scopus 로고
    • Reactive stroma in prostate cancer progression
    • Tuxhorn, J. A., G. E. Ayala, and D. R. Rowley. 2001. Reactive stroma in prostate cancer progression. J. Urol. 166:2472-2483.
    • (2001) J. Urol. , vol.166 , pp. 2472-2483
    • Tuxhorn, J.A.1    Ayala, G.E.2    Rowley, D.R.3
  • 65
    • 34250848181 scopus 로고    scopus 로고
    • The p110alpha isoform of phosphatidylinositol 3-kinase is essential for polyomavirus middle T antigen-mediated transformation
    • Utermark, T., B. S. Schaffhausen, T. M. Roberts, and J. J. Zhao. 2007. The p110alpha isoform of phosphatidylinositol 3-kinase is essential for polyomavirus middle T antigen-mediated transformation. J. Virol. 81:7069-7076.
    • (2007) J. Virol. , vol.81 , pp. 7069-7076
    • Utermark, T.1    Schaffhausen, B.S.2    Roberts, T.M.3    Zhao, J.J.4
  • 67
    • 33745441050 scopus 로고    scopus 로고
    • c-Jun activation is associated with proliferation and angiogenesis in invasive breast cancer
    • Vleugel, M. M., A. E. Greijer, R. Bos, E. van der Wall, and P. J. van Diest. 2006. c-Jun activation is associated with proliferation and angiogenesis in invasive breast cancer. Hum. Pathol. 37:668-674.
    • (2006) Hum. Pathol. , vol.37 , pp. 668-674
    • Vleugel, M.M.1    Greijer, A.E.2    Bos, R.3    van der Wall, E.4    van Diest, P.J.5
  • 68
    • 10744222860 scopus 로고    scopus 로고
    • Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
    • Wang, S., et al. 2003. Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. Cancer Cell 4:209-221.
    • (2003) Cancer Cell , vol.4 , pp. 209-221
    • Wang, S.1
  • 69
    • 31944448885 scopus 로고    scopus 로고
    • Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation
    • Wang, S., et al. 2006. Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation. Proc. Natl. Acad. Sci. U. S. A. 103:1480-1485.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 1480-1485
    • Wang, S.1
  • 70
    • 0031948388 scopus 로고    scopus 로고
    • Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis
    • Webster, M. A., et al. 1998. Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis. Mol. Cell. Biol. 18:2344-2359.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2344-2359
    • Webster, M.A.1
  • 71
    • 0021828496 scopus 로고
    • Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
    • Whitman, M., D. R. Kaplan, B. Schaffhausen, L. Cantley, and T. M. Roberts. 1985. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature 315:239-242.
    • (1985) Nature , vol.315 , pp. 239-242
    • Whitman, M.1    Kaplan, D.R.2    Schaffhausen, B.3    Cantley, L.4    Roberts, T.M.5
  • 72
    • 37349100945 scopus 로고    scopus 로고
    • Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis
    • Yang, L., et al. 2008. Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell 13:23-35.
    • (2008) Cancer Cell , vol.13 , pp. 23-35
    • Yang, L.1
  • 73
    • 0034520311 scopus 로고    scopus 로고
    • A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo
    • Zhang, J., T. Z. Thomas, S. Kasper, and R. J. Matusik. 2000. A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo. Endocrinology 141:4698-4710.
    • (2000) Endocrinology , vol.141 , pp. 4698-4710
    • Zhang, J.1    Thomas, T.Z.2    Kasper, S.3    Matusik, R.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.