메뉴 건너뛰기




Volumn 58, Issue 5, 2011, Pages

Strontium in the Bone-Implant Interface

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYAPATITE; STRONTIUM; STRONTIUM MALONATE; STRONTIUM RANELATE; UNCLASSIFIED DRUG; BIOACTIVE GLASS 45S5; BIOMATERIAL; GLASS;

EID: 79955960948     PISSN: 16039629     EISSN: 16039629     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (29)

References (158)
  • 1
    • 20044372211 scopus 로고    scopus 로고
    • Total hip arthroplasty in Denmark: Incidence ofprimary operations and revisions during 1996-2002 and estimatedfuture demands
    • Pedersen AB, Johnsen SP, Overgaard S, Soballe K, SorensenHT, Lucht U. Total hip arthroplasty in Denmark: incidence ofprimary operations and revisions during 1996-2002 and estimatedfuture demands. Acta Orthop 2005;76:182-9.
    • (2005) Acta Orthop , vol.76 , pp. 182-189
    • Pedersen, A.B.1    Johnsen, S.P.2    Overgaard, S.3    Soballe, K.4    Sorensen, H.T.5    Lucht, U.6
  • 2
    • 2442641610 scopus 로고    scopus 로고
    • Failurerates for 4762 revision total hip arthroplasties in the NorwegianArthroplasty Register
    • Lie SA, Havelin LI, Furnes ON, Engesaeter LB, Vollset SE. Failurerates for 4762 revision total hip arthroplasties in the NorwegianArthroplasty Register. JBone Joint SurgBr 2004;86:504-9.
    • (2004) JBone Joint SurgBr , vol.86 , pp. 504-509
    • Lie, S.A.1    Havelin, L.I.2    Furnes, O.N.3    Engesaeter, L.B.4    Vollset, S.E.5
  • 3
    • 0022465758 scopus 로고
    • Observations on theeffect of movement on bone ingrowth into porous-surfacedimplants
    • Pilliar RM, Lee JM, Maniatopoulos C. Observations on theeffect of movement on bone ingrowth into porous-surfacedimplants. ClinOrthopRelat Res 1986:108-13.
    • (1986) ClinOrthopRelat Res , pp. 108-113
    • Pilliar, R.M.1    Lee, J.M.2    Maniatopoulos, C.3
  • 4
    • 0028034860 scopus 로고
    • Does earlymicromotion of femoral stem prostheses matter? 4-7-yearstereoradiographic follow-up of 84 cemented prostheses
    • Karrholm J, Borssen B, Lowenhielm G, Snorrason F. Does earlymicromotion of femoral stem prostheses matter? 4-7-yearstereoradiographic follow-up of 84 cemented prostheses. JBoneJoint SurgBr 1994;76:912-7.
    • (1994) JBoneJoint SurgBr , vol.76 , pp. 912-917
    • Karrholm, J.1    Borssen, B.2    Lowenhielm, G.3    Snorrason, F.4
  • 5
    • 0032881417 scopus 로고    scopus 로고
    • The pathology of total joint arthroplasty.II.Mechanisms of implant failure
    • Bauer TW, Schils J. The pathology of total joint arthroplasty.II.Mechanisms of implant failure. Skeletal Radiol 1999;28:483-97.
    • (1999) Skeletal Radiol , vol.28 , pp. 483-497
    • Bauer, T.W.1    Schils, J.2
  • 6
    • 0025052402 scopus 로고
    • Macrophages stimulate boneresorption when they phagocytose particles
    • Murray DW, Rushton N. Macrophages stimulate boneresorption when they phagocytose particles. J Bone Joint Surg Br 1990;72:988-92.
    • (1990) J Bone Joint Surg Br , vol.72 , pp. 988-992
    • Murray, D.W.1    Rushton, N.2
  • 7
    • 0026660573 scopus 로고
    • Polyethylenedebris-induced osteolysis and loosening in uncemented total hiparthroplasty. A cause of late failure
    • Cooper RA, McAllister CM, Borden LS, Bauer TW. Polyethylenedebris-induced osteolysis and loosening in uncemented total hiparthroplasty. A cause of late failure. J Arthroplasty 1992;7:285-90.
    • (1992) J Arthroplasty , vol.7 , pp. 285-290
    • Cooper, R.A.1    McAllister, C.M.2    Borden, L.S.3    Bauer, T.W.4
  • 8
    • 0035034959 scopus 로고    scopus 로고
    • Sealing effect of hydroxyapatite coating on peri-implant migrationof particles. An experimental study in dogs
    • Rahbek O, Overgaard S, Lind M, Bendix K, Bunger C, Soballe K.Sealing effect of hydroxyapatite coating on peri-implant migrationof particles. An experimental study in dogs. J Bone Joint Surg Br 2001;83:441-7.
    • (2001) J Bone Joint Surg Br , vol.83 , pp. 441-447
    • Rahbek, O.1    Overgaard, S.2    Lind, M.3    Bendix, K.4    Bunger, C.5    Soballe, K.6
  • 10
    • 0019435541 scopus 로고
    • Osseointegrated titanium implants. Requirements for ensuring along-lasting, direct bone-to-implant anchorage in man
    • Albrektsson T, Branemark PI, Hansson HA, Lindstrom J. Osseointegrated titanium implants. Requirements for ensuring along-lasting, direct bone-to-implant anchorage in man. ActaOrthop Scand 1981;52:155-70.
    • (1981) ActaOrthop Scand , vol.52 , pp. 155-170
    • Albrektsson, T.1    Branemark, P.I.2    Hansson, H.A.3    Lindstrom, J.4
  • 11
    • 0025481324 scopus 로고
    • Criteria for determining clinicalsuccess with osseointegrated dental implants
    • Zarb GA, Alberktsson T. [Criteria for determining clinicalsuccess with osseointegrated dental implants]. Cah Prothese 1990:19-26.
    • (1990) Cah Prothese , pp. 19-26
    • Zarb, G.A.1    Alberktsson, T.2
  • 12
    • 0025082451 scopus 로고
    • Hydroxyapatite coating enhances fixation ofporous coated implants. A comparison in dogs between press fitand noninterference fit
    • Soballe K, Hansen ES, Brockstedt-Rasmussen H, Pedersen CM, Bunger C. Hydroxyapatite coating enhances fixation ofporous coated implants. A comparison in dogs between press fitand noninterference fit. Acta OrthopScand 1990;61:299-306.
    • (1990) Acta OrthopScand , vol.61 , pp. 299-306
    • Soballe, K.1    Hansen, E.S.2    Brockstedt-Rasmussen, H.3    Pedersen, C.M.4    Bunger, C.5
  • 14
    • 0034782891 scopus 로고    scopus 로고
    • Osteoinduction, osteoconductionand osseointegration
    • Albrektsson T, Johansson C. Osteoinduction, osteoconductionand osseointegration. EurSpine J 2001;10 Suppl 2:S96-101.
    • (2001) EurSpine J , Issue.10 SUPPL. 2
    • Albrektsson, T.1    Johansson, C.2
  • 15
    • 74249117889 scopus 로고    scopus 로고
    • The Nordic Arthroplasty Register Association: Aunique collaboration between 3 national hip arthroplastyregistries with 280,201 THRs
    • Havelin LI, Fenstad AM, Salomonsson R, Mehnert F, Furnes O, Overgaard S, et al. The Nordic Arthroplasty Register Association: aunique collaboration between 3 national hip arthroplastyregistries with 280,201 THRs. Acta Orthop 2009;80:393-401.
    • (2009) Acta Orthop , vol.80 , pp. 393-401
    • Havelin, L.I.1    Fenstad, A.M.2    Salomonsson, R.3    Mehnert, F.4    Furnes, O.5    Overgaard, S.6
  • 16
    • 0027400758 scopus 로고
    • Subsidence, tip, and humpmicromovements of noncoated ribbed femoral prostheses
    • Karrholm J, Snorrason F. Subsidence, tip, and humpmicromovements of noncoated ribbed femoral prostheses. ClinOrthopRelat Res 1993:50-60.
    • (1993) ClinOrthopRelat Res , pp. 50-60
    • Karrholm, J.1    Snorrason, F.2
  • 17
    • 70349912740 scopus 로고    scopus 로고
    • CrackRevision improves fixation of uncemented ha-coated implantscompared with reaming: An experiment in dogs
    • Baas J, Elmengaard B, Jakobsen T, Bechtold J, Soballe K. CrackRevision Improves Fixation of Uncemented HA-coated ImplantsCompared with Reaming: An Experiment in Dogs. Clin Orthop Relat Res 2009.
    • (2009) Clin Orthop Relat Res
    • Baas, J.1    Elmengaard, B.2    Jakobsen, T.3    Bechtold, J.4    Soballe, K.5
  • 18
    • 77954537672 scopus 로고    scopus 로고
    • Enhanced osteointegration of orthopaedic implant gradientcoating composed of bioactive glass and nanohydroxyapatite
    • Xie XH, Yu XW, Zeng SX, Du RL, Hu YH, Yuan Z, et al. Enhanced osteointegration of orthopaedic implant gradientcoating composed of bioactive glass and nanohydroxyapatite. J Mater Sci Mater Med 2010.
    • (2010) J Mater Sci Mater Med
    • Xie, X.H.1    Yu, X.W.2    Zeng, S.X.3    Du, R.L.4    Hu, Y.H.5    Yuan, Z.6
  • 20
    • 0018099212 scopus 로고
    • The biology of fracture healing in long bones
    • McKibbin B. The biology of fracture healing in long bones. J Bone Joint Surg Br 1978;60-B:150-62.
    • (1978) J Bone Joint Surg Br , vol.60 B , pp. 150-162
    • McKibbin, B.1
  • 22
    • 0024957026 scopus 로고
    • The biology of fracture healing. An overview forclinicians. Part II
    • Frost HM. The biology of fracture healing. An overview forclinicians. Part II. Clin Orthop Relat Res 1989:294-309.
    • (1989) Clin Orthop Relat Res , pp. 294-309
    • Frost, H.M.1
  • 23
    • 0031734171 scopus 로고    scopus 로고
    • The cell and molecular biology of fracturehealing
    • Einhorn TA. The cell and molecular biology of fracturehealing. Clin Orthop Relat Res 1998:S7-21.
    • (1998) Clin Orthop Relat Res
    • Einhorn, T.A.1
  • 24
    • 59449098083 scopus 로고    scopus 로고
    • Local bisphosphonate treatment increases fixation ofhydroxyapatite-coated implants inserted with bone compaction
    • Jakobsen T, Baas J, Kold S, Bechtold JE, Elmengaard B, Soballe K. Local bisphosphonate treatment increases fixation ofhydroxyapatite-coated implants inserted with bone compaction. J Orthop Res 2009;27:189-94.
    • (2009) J Orthop Res , vol.27 , pp. 189-194
    • Jakobsen, T.1    Baas, J.2    Kold, S.3    Bechtold, J.E.4    Elmengaard, B.5    Soballe, K.6
  • 26
    • 0342601513 scopus 로고    scopus 로고
    • Biomechanical characterization of osseointegration duringhealing: An experimental in vivo study in the rat
    • Branemark R, Ohrnell LO, Nilsson P, Thomsen P. Biomechanical characterization of osseointegration duringhealing: an experimental in vivo study in the rat. Biomaterials 1997;18:969-78.
    • (1997) Biomaterials , vol.18 , pp. 969-978
    • Branemark, R.1    Ohrnell, L.O.2    Nilsson, P.3    Thomsen, P.4
  • 28
    • 0026551917 scopus 로고
    • On Wolff's law of trabecular architecture
    • Turner CH. On Wolff's law of trabecular architecture. JBiomech 1992;25:1-9.
    • (1992) JBiomech , vol.25 , pp. 1-9
    • Turner, C.H.1
  • 29
    • 1842840921 scopus 로고    scopus 로고
    • A 2003 update of bone physiology and Wolff's Lawfor clinicians
    • Frost HM. A 2003 update of bone physiology and Wolff's Lawfor clinicians. Angle Orthod 2004;74:3-15.
    • (2004) Angle Orthod , vol.74 , pp. 3-15
    • Frost, H.M.1
  • 30
    • 0020189813 scopus 로고
    • Review of cancellous and cortical bone healingafter fracture or osteotomy
    • Elkouri ER. Review of cancellous and cortical bone healingafter fracture or osteotomy. J Am Podiatry Assoc 1982;72:464-6.
    • (1982) J Am Podiatry Assoc , vol.72 , pp. 464-466
    • Elkouri, E.R.1
  • 32
    • 0036166394 scopus 로고    scopus 로고
    • Properties of osteoconductive biomaterials: Calcium phosphates
    • LeGeros RZ. Properties of osteoconductive biomaterials:calcium phosphates. ClinOrthopRelat Res 2002:81-98.
    • (2002) ClinOrthopRelat Res , pp. 81-98
    • Legeros, R.Z.1
  • 34
    • 0026879035 scopus 로고
    • Bioactive ceramics for periodontaltreatment: Comparative studies in the Patus monkey
    • Wilson J, Low SB. Bioactive ceramics for periodontaltreatment: comparative studies in the Patus monkey. J Appl Biomater 1992;3:123-9.
    • (1992) J Appl Biomater , vol.3 , pp. 123-129
    • Wilson, J.1    Low, S.B.2
  • 35
    • 0343298498 scopus 로고
    • Magnisium andStrontium Interaction with Carbonate-Containing Hydroxyapatitein Aqueous Medium
    • Bigi AMF; Ripamonti, A; Roveri, N;. Magnisium andStrontium Interaction with Carbonate-Containing Hydroxyapatitein Aqueous Medium. Journal of Inorganic Biochemistry 1981;15.
    • (1981) Journal of Inorganic Biochemistry , pp. 15
    • Bigi, A.M.F.1    Ripamonti, A.2    Roveri, N.3
  • 37
    • 0033668244 scopus 로고    scopus 로고
    • Calcium phosphate coatings for fixation of boneimplants: Evaluated mechanically and histologically bystereological methods
    • Overgaard S. Calcium phosphate coatings for fixation of boneimplants: Evaluated mechanically and histologically bystereological methods. Acta Orthopaedica 2000;71:74.
    • (2000) Acta Orthopaedica , vol.71 , pp. 74
    • Overgaard, S.1
  • 38
    • 0027171681 scopus 로고
    • Biodegradation and bioresorption of calciumphosphate ceramics
    • LeGeros RZ. Biodegradation and bioresorption of calciumphosphate ceramics. ClinMater 1993;14:65-88.
    • (1993) ClinMater , vol.14 , pp. 65-88
    • Legeros, R.Z.1
  • 39
    • 0034806932 scopus 로고    scopus 로고
    • Time-dependent mechanical properties of HA/TCPparticles in relation to morsellized bone grafts for use inimpaction grafting
    • Verdonschot N, van Hal CT, Schreurs BW, Buma P, Huiskes R, Slooff TJ. Time-dependent mechanical properties of HA/TCPparticles in relation to morsellized bone grafts for use inimpaction grafting. J Biomed Mater Res 2001;58:599-604.
    • (2001) J Biomed Mater Res , vol.58 , pp. 599-604
    • Verdonschot, N.1    van Hal, C.T.2    Schreurs, B.W.3    Buma, P.4    Huiskes, R.5    Slooff, T.J.6
  • 40
    • 33846872815 scopus 로고    scopus 로고
    • Osteogenic protein-1 increases the fixation of implants graftedwith morcellised bone allograft and ProOsteon bone substitute:An experimental study in dogs
    • Jensen TB, Overgaard S, Lind M, Rahbek O, Bunger C, Soballe K. Osteogenic protein-1 increases the fixation of implants graftedwith morcellised bone allograft and ProOsteon bone substitute:an experimental study in dogs. J Bone Joint Surg Br 2007;89:121-6.
    • (2007) J Bone Joint Surg Br , vol.89 , pp. 121-126
    • Jensen, T.B.1    Overgaard, S.2    Lind, M.3    Rahbek, O.4    Bunger, C.5    Soballe, K.6
  • 41
    • 57749118781 scopus 로고    scopus 로고
    • Ceramicbone graft substitute with equine bone protein extract iscomparable to allograft in terms of implant fixation: A study indogs
    • Baas J, Elmengaard B, Bechtold J, Chen X, Soballe K. Ceramicbone graft substitute with equine bone protein extract iscomparable to allograft in terms of implant fixation: a study indogs. Acta Orthop 2008;79:841-50.
    • (2008) Acta Orthop , vol.79 , pp. 841-850
    • Baas, J.1    Elmengaard, B.2    Bechtold, J.3    Chen, X.4    Soballe, K.5
  • 42
    • 0028197668 scopus 로고
    • Hydroxyapatite coatings
    • Thomas KA. Hydroxyapatite coatings. Orthopedics 1994;17:267-78.
    • (1994) Orthopedics , vol.17 , pp. 267-278
    • Thomas, K.A.1
  • 43
    • 0027381478 scopus 로고
    • Hydroxyapatite ceramic coating for bone implantfixation. Mechanical and histological studies in dogs
    • Soballe K. Hydroxyapatite ceramic coating for bone implantfixation. Mechanical and histological studies in dogs. ActaOrthopScandSuppl 1993;255:1-58.
    • (1993) ActaOrthopScandSuppl , vol.255 , pp. 1-58
    • Soballe, K.1
  • 44
    • 77958111944 scopus 로고    scopus 로고
    • Amorphous calcium (ortho)phosphates
    • Dorozhkin SV. Amorphous calcium (ortho)phosphates. ActaBiomater 2010.
    • (2010) ActaBiomater
    • Dorozhkin, S.V.1
  • 45
    • 0001661406 scopus 로고    scopus 로고
    • The current status of hydroxyapatitecoating of prostheses
    • Soballe K, Overgaard S. The current status of hydroxyapatitecoating of prostheses. J Bone Joint Surg Br 1996;78:689-91.
    • (1996) J Bone Joint Surg Br , vol.78 , pp. 689-691
    • Soballe, K.1    Overgaard, S.2
  • 46
    • 0030854416 scopus 로고    scopus 로고
    • Improved fixation of porous-coated versus grit-blasted surfacetexture of hydroxyapatite-coated implants in dogs
    • Overgaard S, Lind M, Rahbek O, Bunger C, Soballe K. Improved fixation of porous-coated versus grit-blasted surfacetexture of hydroxyapatite-coated implants in dogs. Acta OrthopScand 1997;68:337-43.
    • (1997) Acta OrthopScand , vol.68 , pp. 337-343
    • Overgaard, S.1    Lind, M.2    Rahbek, O.3    Bunger, C.4    Soballe, K.5
  • 47
    • 0033080911 scopus 로고    scopus 로고
    • Direct morphologicalcomparison of vacuum plasma sprayed and detonation gunsprayed hydroxyapatite coatings for orthopaedic applications
    • Gledhill HC, Turner IG, Doyle C. Direct morphologicalcomparison of vacuum plasma sprayed and detonation gunsprayed hydroxyapatite coatings for orthopaedic applications. Biomaterials 1999;20:315-22.
    • (1999) Biomaterials , vol.20 , pp. 315-322
    • Gledhill, H.C.1    Turner, I.G.2    Doyle, C.3
  • 48
    • 17144463445 scopus 로고    scopus 로고
    • Electrochemically assisted deposition of thin calciumphosphate coatings at near-physiological pH and temperature
    • Rossler S, Sewing A, Stolzel M, Born R, Scharnweber D, Dard M, et al. Electrochemically assisted deposition of thin calciumphosphate coatings at near-physiological pH and temperature. JBiomed Mater Res A 2003;64:655-63.
    • (2003) JBiomed Mater Res A , vol.64 , pp. 655-663
    • Rossler, S.1    Sewing, A.2    Stolzel, M.3    Born, R.4    Scharnweber, D.5    Dard, M.6
  • 50
    • 0029043049 scopus 로고
    • Six-year results ofhydroxyapatite-coated total hip replacement
    • Geesink RG, Hoefnagels NH. Six-year results ofhydroxyapatite-coated total hip replacement. J Bone Joint Surg Br 1995;77:534-47.
    • (1995) J Bone Joint Surg Br , vol.77 , pp. 534-547
    • Geesink, R.G.1    Hoefnagels, N.H.2
  • 51
    • 35648983493 scopus 로고    scopus 로고
    • Effect of hydroxyapatite coating on risk of revisionafter primary total hip arthroplasty in younger patients: Findingsfrom the Danish Hip Arthroplasty Registry
    • Paulsen A, Pedersen AB, Johnsen SP, Riis A, Lucht U, Overgaard S. Effect of hydroxyapatite coating on risk of revisionafter primary total hip arthroplasty in younger patients: findingsfrom the Danish Hip Arthroplasty Registry. Acta Orthop 2007;78:622-8.
    • (2007) Acta Orthop , vol.78 , pp. 622-628
    • Paulsen, A.1    Pedersen, A.B.2    Johnsen, S.P.3    Riis, A.4    Lucht, U.5    Overgaard, S.6
  • 52
    • 0027381478 scopus 로고
    • Hydroxyapatite ceramic coating for bone implantfixation. Mechanical and histological studies in dogs
    • Soballe K. Hydroxyapatite ceramic coating for bone implantfixation. Mechanical and histological studies in dogs. Acta OrthopScand Suppl 1993;255:1-58.
    • (1993) Acta OrthopScand Suppl , vol.255 , pp. 1-58
    • Soballe, K.1
  • 53
    • 0026832935 scopus 로고
    • Tissueingrowth into titanium and hydroxyapatite-coated implantsduring stable and unstable mechanical conditions
    • Soballe K, Hansen ES, H BR, Jorgensen PH, Bunger C. Tissueingrowth into titanium and hydroxyapatite-coated implantsduring stable and unstable mechanical conditions. J Orthop Res 1992;10:285-99.
    • (1992) J Orthop Res , vol.10 , pp. 285-299
    • Soballe, K.1    Hansen, E.S.2    Br, H.3    Jorgensen, P.H.4    Bunger, C.5
  • 54
    • 75749122673 scopus 로고    scopus 로고
    • The effect on bone growth enhancement of implant coatings withhydroxyapatite and collagen deposited electrochemically and byplasma spray
    • Daugaard H, Elmengaard B, Bechtold JE, Jensen T, Soballe K. The effect on bone growth enhancement of implant coatings withhydroxyapatite and collagen deposited electrochemically and byplasma spray. J Biomed Mater Res A 2010;92:913-21.
    • (2010) J Biomed Mater Res A , vol.92 , pp. 913-921
    • Daugaard, H.1    Elmengaard, B.2    Bechtold, J.E.3    Jensen, T.4    Soballe, K.5
  • 55
    • 67649124270 scopus 로고    scopus 로고
    • In vivostudy of porous strontium-doped calcium polyphosphatescaffolds for bone substitute applications
    • Tian M, Chen F, Song W, Song Y, Chen Y, Wan C, et al. In vivostudy of porous strontium-doped calcium polyphosphatescaffolds for bone substitute applications. JMaterSciMaterMed 2009;20:1505-12.
    • (2009) JMaterSciMaterMed , vol.20 , pp. 1505-1512
    • Tian, M.1    Chen, F.2    Song, W.3    Song, Y.4    Chen, Y.5    Wan, C.6
  • 56
    • 0027236835 scopus 로고
    • Age and disease-related changes in the mineralof bone
    • Grynpas M. Age and disease-related changes in the mineralof bone. Calcif Tissue Int 1993;53 Suppl 1:S57-64.
    • (1993) Calcif Tissue Int , Issue.53 SUPPL. 1
    • Grynpas, M.1
  • 57
    • 33845605872 scopus 로고    scopus 로고
    • Chemicalcomposition, crystal size and lattice structural changes afterincorporation of strontium into biomimetic apatite
    • Li ZY, Lam WM, Yang C, Xu B, Ni GX, Abbah SA, et al. Chemicalcomposition, crystal size and lattice structural changes afterincorporation of strontium into biomimetic apatite. Biomaterials 2007;28:1452-60.
    • (2007) Biomaterials , vol.28 , pp. 1452-1460
    • Li, Z.Y.1    Lam, W.M.2    Yang, C.3    Xu, B.4    Ni, G.X.5    Abbah, S.A.6
  • 58
    • 0031022028 scopus 로고    scopus 로고
    • Effects of strontium ions on growth and dissolution ofhydroxyapatite and on bone mineral detection
    • Christoffersen J, Christoffersen MR, Kolthoff N, Barenholdt O. Effects of strontium ions on growth and dissolution ofhydroxyapatite and on bone mineral detection. Bone 1997;20:47-54
    • (1997) Bone , vol.20 , pp. 47-54
    • Christoffersen, J.1    Christoffersen, M.R.2    Kolthoff, N.3    Barenholdt, O.4
  • 59
    • 0021690284 scopus 로고
    • Surface-active biomaterials
    • Hench LL, Wilson J. Surface-active biomaterials. Science 1984;226:630-6.
    • (1984) Science , vol.226 , pp. 630-636
    • Hench, L.L.1    Wilson, J.2
  • 60
  • 64
    • 0035876206 scopus 로고    scopus 로고
    • Silica-based bioactiveglasses modulate expression of bone morphogenetic protein-2mRNA in Saos-2 osteoblasts in vitro
    • Gao T, Aro HT, Ylanen H, Vuorio E. Silica-based bioactiveglasses modulate expression of bone morphogenetic protein-2mRNA in Saos-2 osteoblasts in vitro. Biomaterials 2001;22:1475-83.
    • (2001) Biomaterials , vol.22 , pp. 1475-1483
    • Gao, T.1    Aro, H.T.2    Ylanen, H.3    Vuorio, E.4
  • 66
    • 0034578186 scopus 로고    scopus 로고
    • Bioactive glass granules forregeneration of human periodontal defects
    • Rosenberg ES, Fox GK, Cohen C. Bioactive glass granules forregeneration of human periodontal defects. JEsthetDent 2000;12:248-57.
    • (2000) JEsthetDent , vol.12 , pp. 248-257
    • Rosenberg, E.S.1    Fox, G.K.2    Cohen, C.3
  • 67
    • 0027667150 scopus 로고
    • Bioactiveglass particles of narrow size range: A new material for the repairof bone defects
    • Schepers EJ, Ducheyne P, Barbier L, Schepers S. Bioactiveglass particles of narrow size range: a new material for the repairof bone defects. ImplantDent 1993;2:151-6.
    • (1993) ImplantDent , vol.2 , pp. 151-156
    • Schepers, E.J.1    Ducheyne, P.2    Barbier, L.3    Schepers, S.4
  • 68
    • 0032036099 scopus 로고    scopus 로고
    • Silicate glass coating on Ti-basedimplants
    • Pazo A, Saiz E, Tomsia AP. Silicate glass coating on Ti-basedimplants. Acta Materialia 1998;46:2551-8.
    • (1998) Acta Materialia , vol.46 , pp. 2551-2558
    • Pazo, A.1    Saiz, E.2    Tomsia, A.P.3
  • 69
    • 79955976105 scopus 로고    scopus 로고
    • Bioactive glassengineered coatings for Ti6Al4V alloys: Influence of strontiumsubstitution for calcium on sintering behaviour
    • Lotfibakhshaiesh N, Brauer DS, Hill RG. Bioactive glassengineered coatings for Ti6Al4V alloys: Influence of strontiumsubstitution for calcium on sintering behaviour. Journal of Non-Crystalline Solids; 2009.
    • (2009) Journal of Non-Crystalline Solids
    • Lotfibakhshaiesh, N.1    Brauer, D.S.2    Hill, R.G.3
  • 70
    • 79955973111 scopus 로고    scopus 로고
    • Strontium-based GlassPolyalkenoate Cements for Luting Applications in the Skeleton
    • Clarkin O, Boyd D, Towler MR. Strontium-based GlassPolyalkenoate Cements for Luting Applications in the Skeleton. J Biomater Appl 2008.
    • (2008) J Biomater Appl
    • Clarkin, O.1    Boyd, D.2    Towler, M.R.3
  • 71
    • 40749090892 scopus 로고    scopus 로고
    • The processing, mechanicalproperties and bioactivity of strontium based glass polyalkenoatecements
    • Wren A, Boyd D, Towler MR. The processing, mechanicalproperties and bioactivity of strontium based glass polyalkenoatecements. J Mater Sci Mater Med 2008;19:1737-43.
    • (2008) J Mater Sci Mater Med , vol.19 , pp. 1737-1743
    • Wren, A.1    Boyd, D.2    Towler, M.R.3
  • 72
    • 33744824440 scopus 로고    scopus 로고
    • An investigation into thestructure and reactivity of calcium-zinc-silicate ionomer glassesusing MAS-NMR spectroscopy
    • Boyd D, Towler MR, Law RV, Hill RG. An investigation into thestructure and reactivity of calcium-zinc-silicate ionomer glassesusing MAS-NMR spectroscopy. JMaterSciMaterMed 2006;17:397-402.
    • (2006) JMaterSciMaterMed , vol.17 , pp. 397-402
    • Boyd, D.1    Towler, M.R.2    Law, R.V.3    Hill, R.G.4
  • 73
    • 0030190306 scopus 로고    scopus 로고
    • An alternative view of the degradation of bioglass
    • Hill R, Er. An alternative view of the degradation of bioglass. Journal of Material Science Letters 1996;15:1122-5.
    • (1996) Journal of Material Science Letters , vol.15 , pp. 1122-1125
    • Hill, R.E.1
  • 75
    • 0020614306 scopus 로고
    • The biology of bone graft repair
    • Burchardt H. The biology of bone graft repair. Clin Orthop Relat Res 1983:28-42.
    • (1983) Clin Orthop Relat Res , pp. 28-42
    • Burchardt, H.1
  • 79
    • 0036120764 scopus 로고    scopus 로고
    • Bone allografts pretreated with abisphosphonate are not resorbed
    • Aspenberg P, Astrand J. Bone allografts pretreated with abisphosphonate are not resorbed. Acta OrthopScand 2002;73:20-3.
    • (2002) Acta OrthopScand , vol.73 , pp. 20-23
    • Aspenberg, P.1    Astrand, J.2
  • 80
    • 42249099973 scopus 로고    scopus 로고
    • The effect of pretreating morselized allograft bone withrhBMP-2 and/or pamidronate on the fixation of porous Ti and HAcoatedimplants
    • Baas J, Elmengaard B, Jensen TB, Jakobsen T, Andersen NT, Soballe K. The effect of pretreating morselized allograft bone withrhBMP-2 and/or pamidronate on the fixation of porous Ti and HAcoatedimplants. Biomaterials 2008;29:2915-22.
    • (2008) Biomaterials , vol.29 , pp. 2915-2922
    • Baas, J.1    Elmengaard, B.2    Jensen, T.B.3    Jakobsen, T.4    Andersen, N.T.5    Soballe, K.6
  • 82
    • 0027316220 scopus 로고
    • An uncoupling agent containing strontiumprevents bone loss by depressing bone resorption andmaintaining bone formation in estrogen-deficient rats
    • Marie PJ, Hott M, Modrowski D, De Pollak C, Guillemain J, Deloffre P, et al. An uncoupling agent containing strontiumprevents bone loss by depressing bone resorption andmaintaining bone formation in estrogen-deficient rats. J BoneMiner Res 1993;8:607-15.
    • (1993) J BoneMiner Res , vol.8 , pp. 607-615
    • Marie, P.J.1    Hott, M.2    Modrowski, D.3    de Pollak, C.4    Guillemain, J.5    Deloffre, P.6
  • 83
    • 4344568941 scopus 로고    scopus 로고
    • The Biological role of Strontium
    • Pors Nielsen S. The Biological role of Strontium. Bone 2004;35:583-8.
    • (2004) Bone , vol.35 , pp. 583-588
    • Pors Nielsen, S.1
  • 84
    • 0342819703 scopus 로고
    • External counting of Ca47 and Sr85in studies of localised skeletal lesions in man
    • Bauer GC, Wendeberg B. External counting of Ca47 and Sr85in studies of localised skeletal lesions in man. J Bone Joint Surg Br 1959;41-B:558-80.
    • (1959) J Bone Joint Surg Br , vol.41 B , pp. 558-580
    • Bauer, G.C.1    Wendeberg, B.2
  • 86
    • 0029812110 scopus 로고    scopus 로고
    • Strontium distribution and interactions with bonemineral in monkey iliac bone after strontium salt (S 12911)administration
    • Boivin G, Deloffre P, Perrat B, Panczer G, Boudeulle M, Mauras Y, et al. Strontium distribution and interactions with bonemineral in monkey iliac bone after strontium salt (S 12911)administration. J Bone Miner Res 1996;11:1302-11.
    • (1996) J Bone Miner Res , vol.11 , pp. 1302-1311
    • Boivin, G.1    Deloffre, P.2    Perrat, B.3    Panczer, G.4    Boudeulle, M.5    Mauras, Y.6
  • 87
    • 55049124913 scopus 로고    scopus 로고
    • Effective doses for strontium ranelate
    • author reply 5-7
    • Marie PJ. Effective doses for strontium ranelate. OsteoporosInt 2008;19:1813; author reply 5-7.
    • (2008) OsteoporosInt , vol.19 , pp. 1813
    • Marie, P.J.1
  • 89
    • 0031763862 scopus 로고    scopus 로고
    • Interspeciesdifferences in bone composition, density, and quality: Potentialimplications for in vivo bone research
    • Aerssens J, Boonen S, Lowet G, Dequeker J. Interspeciesdifferences in bone composition, density, and quality: potentialimplications for in vivo bone research. Endocrinology 1998;139:663-70.
    • (1998) Endocrinology , pp. 663-670
    • Aerssens, J.1    Boonen, S.2    Lowet, G.3    Dequeker, J.4
  • 90
    • 46249115916 scopus 로고    scopus 로고
    • Application ofinductively coupled plasma-mass spectrometry (ICP-MS) andquality assurance to study the incorporation of strontium intobone, bone marrow, and teeth of dogs after one month oftreatment with strontium malonate
    • Raffalt AC, Andersen JE, Christgau S. Application ofinductively coupled plasma-mass spectrometry (ICP-MS) andquality assurance to study the incorporation of strontium intobone, bone marrow, and teeth of dogs after one month oftreatment with strontium malonate. AnalBioanalChem 2008;391:2199-207.
    • (2008) AnalBioanalChem , vol.391 , pp. 2199-2207
    • Raffalt, A.C.1    Andersen, J.E.2    Christgau, S.3
  • 92
    • 72949086648 scopus 로고    scopus 로고
    • Calcium sensing receptor-dependent and -independentactivation of osteoblast replication and survival by strontiumranelate
    • Fromigue O, Hay E, Barbara A, Petrel C, Traiffort E, Ruat M, et al. Calcium sensing receptor-dependent and -independentactivation of osteoblast replication and survival by strontiumranelate. J Cell Mol Med 2009.
    • (2009) J Cell Mol Med
    • Fromigue, O.1    Hay, E.2    Barbara, A.3    Petrel, C.4    Traiffort, E.5    Ruat, M.6
  • 93
    • 43149125403 scopus 로고    scopus 로고
    • Strontium ranelate promotes osteoblastic cellreplication through at least two different mechanisms
    • Caverzasio J. Strontium ranelate promotes osteoblastic cellreplication through at least two different mechanisms. Bone 2008;42:1131-6.
    • (2008) Bone , vol.42 , pp. 1131-1136
    • Caverzasio, J.1
  • 94
    • 62149087855 scopus 로고    scopus 로고
    • Strontiumranelate treatment of human primary osteoblasts promotes anosteocyte-like phenotype while eliciting an osteoprotegerinresponse
    • Atkins GJ, Welldon KJ, Halbout P, Findlay DM. Strontiumranelate treatment of human primary osteoblasts promotes anosteocyte-like phenotype while eliciting an osteoprotegerinresponse. OsteoporosInt 2009;20:653-64.
    • (2009) OsteoporosInt , vol.20 , pp. 653-664
    • Atkins, G.J.1    Welldon, K.J.2    Halbout, P.3    Findlay, D.M.4
  • 95
    • 46749141271 scopus 로고    scopus 로고
    • The calcium-sensing receptor in bone
    • Yamaguchi T. The calcium-sensing receptor in bone. JBoneMinerMetab 2008;26:301-11.
    • (2008) JBoneMinerMetab , vol.26 , pp. 301-311
    • Yamaguchi, T.1
  • 96
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum SL. Bone resorption by osteoclasts. Science 2000;289:1504-8.
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 97
    • 58649120832 scopus 로고    scopus 로고
    • The calcium-sensing receptor is involvedin strontium ranelate-induced osteoclast apoptosis. New insightsinto the associated signaling pathways
    • Hurtel-Lemaire AS, Mentaverri R, Caudrillier A, Cournarie F, Wattel A, Kamel S, et al. The calcium-sensing receptor is involvedin strontium ranelate-induced osteoclast apoptosis. New insightsinto the associated signaling pathways. JBiolChem 2009;284:575-84.
    • (2009) JBiolChem , vol.284 , pp. 575-584
    • Hurtel-Lemaire, A.S.1    Mentaverri, R.2    Caudrillier, A.3    Cournarie, F.4    Wattel, A.5    Kamel, S.6
  • 98
    • 37349123534 scopus 로고    scopus 로고
    • Dual effect ofstrontium ranelate: Stimulation of osteoblast differentiation andinhibition of osteoclast formation and resorption in vitro
    • Bonnelye E, Chabadel A, Saltel F, Jurdic P. Dual effect ofstrontium ranelate: stimulation of osteoblast differentiation andinhibition of osteoclast formation and resorption in vitro. Bone 2008;42:129-38.
    • (2008) Bone , vol.42 , pp. 129-138
    • Bonnelye, E.1    Chabadel, A.2    Saltel, F.3    Jurdic, P.4
  • 99
    • 0034902167 scopus 로고    scopus 로고
    • Strontium ranelate inhibits bone resorption while maintainingbone formation in alveolar bone in monkeys (Macaca fascicularis)
    • Buehler J, Chappuis P, Saffar JL, Tsouderos Y, Vignery A. Strontium ranelate inhibits bone resorption while maintainingbone formation in alveolar bone in monkeys (Macaca fascicularis). Bone 2001;29:176-9.
    • (2001) Bone , vol.29 , pp. 176-179
    • Buehler, J.1    Chappuis, P.2    Saffar, J.L.3    Tsouderos, Y.4    Vignery, A.5
  • 100
    • 0030176233 scopus 로고    scopus 로고
    • Thedivalent strontium salt S12911 enhances bone cell replication andbone formation in vitro
    • Canalis E, Hott M, Deloffre P, Tsouderos Y, Marie PJ. Thedivalent strontium salt S12911 enhances bone cell replication andbone formation in vitro. Bone 1996;18:517-23.
    • (1996) Bone , vol.18 , pp. 517-523
    • Canalis, E.1    Hott, M.2    Deloffre, P.3    Tsouderos, Y.4    Marie, P.J.5
  • 101
    • 0142122898 scopus 로고    scopus 로고
    • S 12911-2inhibits osteoclastic bone resorption in vitro
    • Takahashi N, Sasaki T, Tsouderos Y, Suda T. S 12911-2inhibits osteoclastic bone resorption in vitro. JBone MinerRes 2003;18:1082-7.
    • (2003) JBone MinerRes , vol.18 , pp. 1082-1087
    • Takahashi, N.1    Sasaki, T.2    Tsouderos, Y.3    Suda, T.4
  • 103
    • 24144474976 scopus 로고    scopus 로고
    • Longtermstrontium ranelate administration in monkeys preservescharacteristics of bone mineral crystals and degree ofmineralization of bone
    • Farlay D, Boivin G, Panczer G, Lalande A, Meunier PJ. Longtermstrontium ranelate administration in monkeys preservescharacteristics of bone mineral crystals and degree ofmineralization of bone. J Bone Miner Res 2005;20:1569-78.
    • (2005) J Bone Miner Res , vol.20 , pp. 1569-1578
    • Farlay, D.1    Boivin, G.2    Panczer, G.3    Lalande, A.4    Meunier, P.J.5
  • 104
    • 0025053086 scopus 로고
    • Effects of low doses of strontium onbone quality and quantity in rats
    • Grynpas MD, Marie PJ. Effects of low doses of strontium onbone quality and quantity in rats. Bone 1990;11:313-9.
    • (1990) Bone , vol.11 , pp. 313-319
    • Grynpas, M.D.1    Marie, P.J.2
  • 105
    • 38549175745 scopus 로고    scopus 로고
    • Histomorphometric and mu-CT Analysis of Bone Biopsiesfrom Postmenopausal Osteoporotic Women Treated withStrontium Ranelate
    • Arlot ME, Jiang Y, Genant HK, Zhao J, Burt-Pichat B, Roux JP, et al. Histomorphometric and mu-CT Analysis of Bone Biopsiesfrom Postmenopausal Osteoporotic Women Treated withStrontium Ranelate. JBone MinerRes 2007.
    • (2007) JBone MinerRes
    • Arlot, M.E.1    Jiang, Y.2    Genant, H.K.3    Zhao, J.4    Burt-Pichat, B.5    Roux, J.P.6
  • 106
    • 0029960972 scopus 로고    scopus 로고
    • Strontium increases vertebral bone volume in ratsat a low dose that does not induce detectable mineralizationdefect
    • Grynpas MD, Hamilton E, Cheung R, Tsouderos Y, Deloffre P, Hott M, et al. Strontium increases vertebral bone volume in ratsat a low dose that does not induce detectable mineralizationdefect. Bone 1996;18:253-9.
    • (1996) Bone , vol.18 , pp. 253-259
    • Grynpas, M.D.1    Hamilton, E.2    Cheung, R.3    Tsouderos, Y.4    Deloffre, P.5    Hott, M.6
  • 107
    • 17644382533 scopus 로고    scopus 로고
    • Strontium ranelate improves bone resistance by increasing bonemass and improving architecture in intact female rats
    • Ammann P, Shen V, Robin B, Mauras Y, Bonjour JP, Rizzoli R. Strontium ranelate improves bone resistance by increasing bonemass and improving architecture in intact female rats. JBoneMinerRes 2004;19:2012-20.
    • (2004) JBoneMinerRes , vol.19 , pp. 2012-2020
    • Ammann, P.1    Shen, V.2    Robin, B.3    Mauras, Y.4    Bonjour, J.P.5    Rizzoli, R.6
  • 108
    • 21044447888 scopus 로고    scopus 로고
    • Strontium ranelate reduces therisk of nonvertebral fractures in postmenopausal women withosteoporosis: Treatment of Peripheral Osteoporosis (TROPOS)study
    • Reginster JY, Seeman E, De Vernejoul MC, Adami S, Compston J, Phenekos C, et al. Strontium ranelate reduces therisk of nonvertebral fractures in postmenopausal women withosteoporosis: Treatment of Peripheral Osteoporosis (TROPOS)study. JClinEndocrinolMetab 2005;90:2816-22.
    • (2005) JClinEndocrinolMetab , vol.90 , pp. 2816-2822
    • Reginster, J.Y.1    Seeman, E.2    de Vernejoul, M.C.3    Adami, S.4    Compston, J.5    Phenekos, C.6
  • 109
    • 45349090543 scopus 로고    scopus 로고
    • Effects of long-term strontium ranelatetreatment on the risk of nonvertebral and vertebral fractures inpostmenopausal osteoporosis: Results of a five-year, randomized,placebo-controlled trial
    • Reginster JY, Felsenberg D, Boonen S, Diez-Perez A, Rizzoli R, Brandi ML, et al. Effects of long-term strontium ranelatetreatment on the risk of nonvertebral and vertebral fractures inpostmenopausal osteoporosis: Results of a five-year, randomized,placebo-controlled trial. Arthritis Rheum 2008;58:1687-95.
    • (2008) Arthritis Rheum , vol.58 , pp. 1687-1695
    • Reginster, J.Y.1    Felsenberg, D.2    Boonen, S.3    Diez-Perez, A.4    Rizzoli, R.5    Brandi, M.L.6
  • 111
    • 69949149543 scopus 로고    scopus 로고
    • Effects of long-term strontium ranelatetreatment on vertebral fracture risk in postmenopausal womenwith osteoporosis
    • Meunier PJ, Roux C, Ortolani S, Diaz-Curiel M, Compston J, Marquis P, et al. Effects of long-term strontium ranelatetreatment on vertebral fracture risk in postmenopausal womenwith osteoporosis. Osteoporos Int 2009;20:1663-73.
    • (2009) Osteoporos Int , vol.20 , pp. 1663-1673
    • Meunier, P.J.1    Roux, C.2    Ortolani, S.3    Diaz-Curiel, M.4    Compston, J.5    Marquis, P.6
  • 112
    • 77955909218 scopus 로고    scopus 로고
    • Osteoblast response and osseointegration of a Ti-6Al-4V alloyimplant incorporating strontium
    • Park JW, Kim HK, Kim YJ, Jang JH, Song H, Hanawa T. Osteoblast response and osseointegration of a Ti-6Al-4V alloyimplant incorporating strontium. Acta Biomater 2010;6:2843-51.
    • (2010) Acta Biomater , vol.6 , pp. 2843-2851
    • Park, J.W.1    Kim, H.K.2    Kim, Y.J.3    Jang, J.H.4    Song, H.5    Hanawa, T.6
  • 114
  • 115
    • 58549083107 scopus 로고    scopus 로고
    • Preliminary investigation of novel bone graft substitutesbased on strontium-calcium-zinc-silicate glasses
    • Boyd D, Carroll G, Towler MR, Freeman C, Farthing P, Brook IM. Preliminary investigation of novel bone graft substitutesbased on strontium-calcium-zinc-silicate glasses. JMaterSciMaterMed 2009;20:413-20.
    • (2009) JMaterSciMaterMed , vol.20 , pp. 413-420
    • Boyd, D.1    Carroll, G.2    Towler, M.R.3    Freeman, C.4    Farthing, P.5    Brook, I.M.6
  • 116
    • 65549125400 scopus 로고    scopus 로고
    • Comparison of in vitro and in vivo bioactivity of SrO-CaO-ZnOSiO2glass grafts
    • Towler MR, Boyd D, Freeman C, Brook IM, Farthing P. Comparison of in vitro and in vivo bioactivity of SrO-CaO-ZnOSiO2glass grafts. JBiomaterAppl 2009;23:561-72.
    • (2009) JBiomaterAppl , vol.23 , pp. 561-572
    • Towler, M.R.1    Boyd, D.2    Freeman, C.3    Brook, I.M.4    Farthing, P.5
  • 118
    • 1842853902 scopus 로고    scopus 로고
    • Mechanical interface conditions affect morphology and cellularactivity of sclerotic bone rims forming around experimentalloaded implants
    • Vestermark MT, Bechtold JE, Swider P, Soballe K. Mechanical interface conditions affect morphology and cellularactivity of sclerotic bone rims forming around experimentalloaded implants. JOrthopRes 2004;22:647-52.
    • (2004) JOrthopRes , vol.22 , pp. 647-652
    • Vestermark, M.T.1    Bechtold, J.E.2    Swider, P.3    Soballe, K.4
  • 119
    • 0024954184 scopus 로고
    • The biology of fracture healing. An overview forclinicians. Part I
    • Frost HM. The biology of fracture healing. An overview forclinicians. Part I. Clin Orthop Relat Res 1989:283-93.
    • (1989) Clin Orthop Relat Res , pp. 283-293
    • Frost, H.M.1
  • 120
  • 121
    • 34047202973 scopus 로고    scopus 로고
    • Local alendronate increases fixation of implants inserted withbone compaction: 12-week canine study
    • Jakobsen T, Kold S, Bechtold JE, Elmengaard B, Soballe K. Local alendronate increases fixation of implants inserted withbone compaction: 12-week canine study. JOrthopRes 2007;25:432-41.
    • (2007) JOrthopRes , vol.25 , pp. 432-441
    • Jakobsen, T.1    Kold, S.2    Bechtold, J.E.3    Elmengaard, B.4    Soballe, K.5
  • 122
    • 33749465470 scopus 로고    scopus 로고
    • Thebovine bone protein lyophilisate Colloss improves fixation ofallografted implants--an experimental study in dogs
    • Baas J, Lamberg A, Jensen TB, Elmengaard B, Soballe K. Thebovine bone protein lyophilisate Colloss improves fixation ofallografted implants--an experimental study in dogs. Acta Orthop 2006;77:791-8.
    • (2006) Acta Orthop , vol.77 , pp. 791-798
    • Baas, J.1    Lamberg, A.2    Jensen, T.B.3    Elmengaard, B.4    Soballe, K.5
  • 123
    • 0028393411 scopus 로고
    • Comparison ofprimate and canine models for bone ingrowth experimentation,with reference to the effect of ovarian function on bone ingrowthpotential
    • Shaw JA, Wilson SC, Bruno A, Paul EM. Comparison ofprimate and canine models for bone ingrowth experimentation,with reference to the effect of ovarian function on bone ingrowthpotential. J Orthop Res 1994;12:268-73.
    • (1994) J Orthop Res , vol.12 , pp. 268-273
    • Shaw, J.A.1    Wilson, S.C.2    Bruno, A.3    Paul, E.M.4
  • 124
    • 0019865454 scopus 로고
    • Boneregeneration in animals and in man. A contribution tounderstanding the relative value of animal experiments to humanpathophysiology
    • Eitel F, Klapp F, Jacobson W, Schweiberer L. Boneregeneration in animals and in man. A contribution tounderstanding the relative value of animal experiments to humanpathophysiology. Arch Orthop Trauma Surg 1981;99:59-64.
    • (1981) Arch Orthop Trauma Surg , vol.99 , pp. 59-64
    • Eitel, F.1    Klapp, F.2    Jacobson, W.3    Schweiberer, L.4
  • 125
    • 0020080012 scopus 로고
    • A quantitative histologic study of boneturnover in young adult beagles
    • Kimmel DB, Jee WS. A quantitative histologic study of boneturnover in young adult beagles. Anat Rec 1982;203:31-45.
    • (1982) Anat Rec , vol.203 , pp. 31-45
    • Kimmel, D.B.1    Jee, W.S.2
  • 127
    • 0036027557 scopus 로고    scopus 로고
    • Effect of load on the early incorporation of impacted morsellizedallografts
    • van der Donk S, Buma P, Verdonschot N, Schreurs BW. Effect of load on the early incorporation of impacted morsellizedallografts. Biomaterials 2002;23:297-303.
    • (2002) Biomaterials , vol.23 , pp. 297-303
    • van der Donk, S.1    Buma, P.2    Verdonschot, N.3    Schreurs, B.W.4
  • 128
    • 0023240947 scopus 로고
    • Porous-coated hipreplacement. The factors governing bone ingrowth, stressshielding, and clinical results
    • Engh CA, Bobyn JD, Glassman AH. Porous-coated hipreplacement. The factors governing bone ingrowth, stressshielding, and clinical results. J Bone Joint Surg Br 1987;69:45-55.
    • (1987) J Bone Joint Surg Br , vol.69 , pp. 45-55
    • Engh, C.A.1    Bobyn, J.D.2    Glassman, A.H.3
  • 129
    • 33745525903 scopus 로고    scopus 로고
    • Periprosthetic proximal bone loss after uncemented hiparthroplasty is related to stem size: DXA measurements in 138patients followed for 2-7 years
    • Skoldenberg OG, Boden HS, Salemyr MO, Ahl TE, Adolphson PY. Periprosthetic proximal bone loss after uncemented hiparthroplasty is related to stem size: DXA measurements in 138patients followed for 2-7 years. Acta Orthop 2006;77:386-92.
    • (2006) Acta Orthop , vol.77 , pp. 386-392
    • Skoldenberg, O.G.1    Boden, H.S.2    Salemyr, M.O.3    Ahl, T.E.4    Adolphson, P.Y.5
  • 132
    • 0030152778 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 enhances bonehealing to unloaded tricalcium phosphate coated implants: Anexperimental study in dogs
    • Lind M, Overgaard S, Soballe K, Nguyen T, OngpipattanakulB, Bunger C. Transforming growth factor-beta 1 enhances bonehealing to unloaded tricalcium phosphate coated implants: anexperimental study in dogs. J Orthop Res 1996;14:343-50.
    • (1996) J Orthop Res , vol.14 , pp. 343-350
    • Lind, M.1    Overgaard, S.2    Soballe, K.3    Nguyen, T.4    Ongpipattanakul, B.5    Bunger, C.6
  • 133
    • 33749494996 scopus 로고    scopus 로고
    • Locallydelivered TGF-beta1 and IGF-1 enhance the fixation of titaniumimplants: A study in dogs
    • Lamberg A, Schmidmaier G, Soballe K, Elmengaard B. Locallydelivered TGF-beta1 and IGF-1 enhance the fixation of titaniumimplants: a study in dogs. Acta Orthop 2006;77:799-805.
    • (2006) Acta Orthop , vol.77 , pp. 799-805
    • Lamberg, A.1    Schmidmaier, G.2    Soballe, K.3    Elmengaard, B.4
  • 134
    • 74249089817 scopus 로고    scopus 로고
    • Effect of local TGF-beta1 and IGF-1 release on implant fixation:Comparison with hydroxyapatite coating: A paired study in dogs
    • Lamberg A, Bechtold JE, Baas J, Soballe K, Elmengaard B. Effect of local TGF-beta1 and IGF-1 release on implant fixation:comparison with hydroxyapatite coating: a paired study in dogs. Acta Orthop 2009;80:499-504.
    • (2009) Acta Orthop , vol.80 , pp. 499-504
    • Lamberg, A.1    Bechtold, J.E.2    Baas, J.3    Soballe, K.4    Elmengaard, B.5
  • 135
    • 0018970317 scopus 로고
    • Theoptimum pore size for the fixation of porous-surfaced metalimplants by the ingrowth of bone
    • Bobyn JD, Pilliar RM, Cameron HU, Weatherly GC. Theoptimum pore size for the fixation of porous-surfaced metalimplants by the ingrowth of bone. Clin Orthop Relat Res 1980:263-70.
    • (1980) Clin Orthop Relat Res , pp. 263-270
    • Bobyn, J.D.1    Pilliar, R.M.2    Cameron, H.U.3    Weatherly, G.C.4
  • 136
    • 31944442279 scopus 로고    scopus 로고
    • Strontium ranelate: A physiological approach foroptimizing bone formation and resorption
    • Marie PJ. Strontium ranelate: a physiological approach foroptimizing bone formation and resorption. Bone 2006;38:S10-S4.
    • (2006) Bone , vol.38
    • Marie, P.J.1
  • 137
    • 0034815044 scopus 로고    scopus 로고
    • Mechanisms of actionand therapeutic potential of strontium in bone
    • Marie PJ, Ammann P, Boivin G, Rey C. Mechanisms of actionand therapeutic potential of strontium in bone. CalcifTissue Int 2001;69:121-9.
    • (2001) CalcifTissue Int , vol.69 , pp. 121-129
    • Marie, P.J.1    Ammann, P.2    Boivin, G.3    Rey, C.4
  • 140
    • 0040153135 scopus 로고
    • The in vivo distribution oftetracyclines in canine bone
    • Harris WH, Jackson RH, Jowsey J. The in vivo distribution oftetracyclines in canine bone. J Bone Joint Surg Am 1962;44-A:1308-20.
    • (1962) J Bone Joint Surg Am , vol.44 A , pp. 1308-1320
    • Harris, W.H.1    Jackson, R.H.2    Jowsey, J.3
  • 141
    • 0026471229 scopus 로고
    • Dodifferent fluorochrome labels give equivalent histomorphometricinformation?
    • Sun TC, Mori S, Roper J, Brown C, Hooser T, Burr DB. Dodifferent fluorochrome labels give equivalent histomorphometricinformation? Bone 1992;13:443-6.
    • (1992) Bone , vol.13 , pp. 443-446
    • Sun, T.C.1    Mori, S.2    Roper, J.3    Brown, C.4    Hooser, T.5    Burr, D.B.6
  • 142
    • 0031758508 scopus 로고    scopus 로고
    • Growth factor stimulation of bone healing. Effectson osteoblasts, osteomies, and implants fixation
    • Lind M. Growth factor stimulation of bone healing. Effectson osteoblasts, osteomies, and implants fixation. Acta OrthopScand Suppl 1998;283:2-37.
    • (1998) Acta OrthopScand Suppl , vol.283 , pp. 2-37
    • Lind, M.1
  • 143
    • 0032468984 scopus 로고    scopus 로고
    • Bisphosphonates: Mechanisms of action
    • Fleisch H. Bisphosphonates: mechanisms of action. EndocrRev 1998;19:80-100.
    • (1998) EndocrRev , vol.19 , pp. 80-100
    • Fleisch, H.1
  • 145
    • 0027686612 scopus 로고
    • The effect of different storagemethods on the mechanical properties of trabecular bone
    • Linde F, Sorensen HC. The effect of different storagemethods on the mechanical properties of trabecular bone. JBiomech 1993;26:1249-52.
    • (1993) JBiomech , vol.26 , pp. 1249-1252
    • Linde, F.1    Sorensen, H.C.2
  • 146
    • 58149306356 scopus 로고    scopus 로고
    • Adjuvant therapies of bone graft around noncementedexperimental orthopedic implants stereologicalmethods and experiments in dogs
    • Baas J. Adjuvant therapies of bone graft around noncementedexperimental orthopedic implants stereologicalmethods and experiments in dogs. Acta OrthopSuppl 2008;79:1-43.
    • (2008) Acta OrthopSuppl , vol.79 , pp. 1-43
    • Baas, J.1
  • 147
    • 0025486306 scopus 로고
    • The influence of supportconditions in the loading fixture on failure mechanisms in thepush-out test: A finite element study
    • Harrigan TP, Kareh J, Harris WH. The influence of supportconditions in the loading fixture on failure mechanisms in thepush-out test: a finite element study. J Orthop Res 1990;8:678-84.
    • (1990) J Orthop Res , vol.8 , pp. 678-684
    • Harrigan, T.P.1    Kareh, J.2    Harris, W.H.3
  • 149
    • 0031042663 scopus 로고    scopus 로고
    • Embedding of bone samples inmethylmethacrylate: An improved method suitable for bonehistomorphometry, histochemistry, and immunohistochemistry
    • Erben RG. Embedding of bone samples inmethylmethacrylate: an improved method suitable for bonehistomorphometry, histochemistry, and immunohistochemistry. JHistochemCytochem 1997;45:307-13.
    • (1997) JHistochemCytochem , vol.45 , pp. 307-313
    • Erben, R.G.1
  • 150
    • 0023913503 scopus 로고
    • Some new, simple and efficient stereologicalmethods and their use in pathological research and diagnosis
    • Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Moller A, Nielsen K, et al. Some new, simple and efficient stereologicalmethods and their use in pathological research and diagnosis. APMIS 1988;96:379-94.
    • (1988) APMIS , vol.96 , pp. 379-394
    • Gundersen, H.J.1    Bendtsen, T.F.2    Korbo, L.3    Marcussen, N.4    Moller, A.5    Nielsen, K.6
  • 152
    • 0034069018 scopus 로고    scopus 로고
    • Efficiency ofsystematic sampling in histomorphometric bone researchillustrated by hydroxyapatite-coated implants: Optimizing thestereological vertical-section design
    • Overgaard S, Soballe K, Jorgen H, Gundersen G. Efficiency ofsystematic sampling in histomorphometric bone researchillustrated by hydroxyapatite-coated implants: optimizing thestereological vertical-section design. J Orthop Res 2000;18:313-21.
    • (2000) J Orthop Res , vol.18 , pp. 313-321
    • Overgaard, S.1    Soballe, K.2    Jorgen, H.3    Gundersen, G.4
  • 153
    • 0026619292 scopus 로고
    • Stereology: The fast lane betweenneuroanatomy and brain function--or still only a tightrope?
    • Gundersen HJ. Stereology: the fast lane betweenneuroanatomy and brain function--or still only a tightrope? ActaNeurol Scand Suppl 1992;137:8-13.
    • (1992) ActaNeurol Scand Suppl , vol.137 , pp. 8-13
    • Gundersen, H.J.1
  • 154
    • 0034978467 scopus 로고    scopus 로고
    • Log-normal distributions across the sciences: Keys and Clues
    • Limpert ES, W Abbt, M. Log-normal Distributions across theSciences: Keys and Clues. Bioscience 2001;51.
    • (2001) Bioscience , pp. 51
    • Limpert, E.S.1    Abbt, W.M.2
  • 156
    • 77949854899 scopus 로고    scopus 로고
    • Strontium ranelatetreatment enhances hydroxyapatite-coated titanium screwsfixation in osteoporotic rats
    • Li Y, Feng G, Gao Y, Luo E, Liu X, Hu J. Strontium ranelatetreatment enhances hydroxyapatite-coated titanium screwsfixation in osteoporotic rats. J Orthop Res 2010;28:578-82.
    • (2010) J Orthop Res , vol.28 , pp. 578-582
    • Li, Y.1    Feng, G.2    Gao, Y.3    Luo, E.4    Liu, X.5    Hu, J.6
  • 158
    • 77649274629 scopus 로고    scopus 로고
    • The effects of strontium-substitutedbioactive glasses on osteoblasts and osteoclasts in vitro
    • Gentleman E, Fredholm YC, Jell G, Lotfibakhshaiesh N, O'Donnell MD, Hill RG, et al. The effects of strontium-substitutedbioactive glasses on osteoblasts and osteoclasts in vitro. Biomaterials 2010;31:3949-56.
    • (2010) Biomaterials , vol.31
    • Gentleman, E.1    Fredholm, Y.C.2    Jell, G.3    Lotfibakhshaiesh, N.4    O'Donnell, M.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.