Efficiency of systematic sampling in histomorphometric bone research illustrated by hydroxyapatite-coated implants: Optimizing the stereological vertical-section design

Journal of Orthopaedic Research

Volumn 18, Issue 2, 2000, Pages 313-321

  Overgaard, Søren ^a   Søballe, Kjeld ^a   Gundersen, Hans Jørgen G ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYAPATITE;

ADULT; AGED; ANALYTIC METHOD; ARTICLE; BONE GRAFT; BONE GROWTH; CLINICAL ARTICLE; DATA ANALYSIS; FEMALE; HUMAN; IMPLANT; MALE; MICROTOME; MORPHOMETRICS; PRIORITY JOURNAL; RESEARCH; SAMPLING; SPINE FUSION; STEREOLOGY;

ADULT; BONE AND BONES; DURAPATITE; FEMALE; HUMAN; MALE; MATHEMATICS; MICROTOMY; MIDDLE AGE; PROSTHESES AND IMPLANTS; SUPPORT, NON-U.S. GOV'T;

EID: 0034069018     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.1100180221     Document Type: Article

References (21)

1. Baddeley AJ, Gundersen HJG, Cruz-Orive LM: Estimation of surface area from vertical sections. J Microsc 142:259-276, 1986
2. Galante J, Rostoker W, Ray RD: Physical properties of trabecular bone. Calcif Tissue Res 5:236-246, 1970
3. Goldstein SA, Matthews LS, Kuhn JL, Hollister SJ: Trabecular bone remodeling: an experimental model [published erratum appears in J Biomech 26:367, 1993]. J Biomech 24(Suppl 1):135-150, 1991
4. Gundersen HJG, Osterby R: Optimizing sampling efficiency of stereological studies in biology: or 'do more less well'. J Microsc 121:65-73, 1981
5. Gundersen HJG, Jensen EB: The efficiency of systematic sampling in stereology and its prediction. J Microsc 147:229-263, 1987
6. Gundersen HJG, Bendtsen TF, Korbo L, Marcussen N, Møller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sørensen FB, Vesterby A, West MJ: Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96:379-394, 1988
7. Gundersen HJG: Stereology: the fast lane between neuroanatomy and brain function - or still only a tightrope? Acta Neurol Scand Suppl 137:8-13, 1992
8. Gundersen HJG, Jensen EB, Kiêu K, Nielsen J: The efficiency of systematic sampling in stereology - reconsidered. J Microsc 193:199-211, 1999
9. Gundersen HJG, Østerby R: Sampling efficiency and biological variation in stereology. Mikroskopie 37(Suppl):143-148, 1980
10. Klein CP, Sauren YM, Modderman WE, van der Waerden JP: A new saw technique improves preparation of bone sections for light and electron microscopy. J Appl Biomater 5:369-373, 1994
11. Nicholson WL: Application of statistical methods in quantitative microscopy. J Microsc 113:223-239, 1978
12. Overgaard S, Søballe K, Josephsen K, Hansen ES, Bünger C: Role of different loading conditions on resorption of hydroxyapatite coating evaluated by histomorphometric and stereological methods. J Orthop Res 14:888-894, 1996
13. Overgaard S, Søballe K, Lind M, Bünger C: Resorption of hydroxyapatite and fluorapatite coatings in man: an experimental study in trabecular bone. J Bone Joint Surg [Br] 79:654-659, 1997
14. Overgaard S, Lind M, Glerup H, Bünger C, Søballe K: Porouscoated versus grit-blasted surface texture of hydroxyapatitecoated implants during controlled micromotion: mechanical and histomorphometric results. J Arthroplasty 13:449-458, 1998
15. Overgaard S, Lind M, Josephsen K, Maunshach AB, Bünger C, Søballe K: Resorption of hydroxyapatite and fluorapatite ceramic coatings on weight-bearing implants: a quantitative and morphological study in dogs. J Biomed Mater Res 39:141-152, 1998
16. Overgaard S, Bromose U, Lind M, Bünger C, Søballe K: The influence of crystallinity of the hydroxyapatite coating on the fixation of implants: mechanical and histomorphometric results. J Bone Joint Surg [Br] 81:725-731, 1999
17. Pakkenberg B, Gundersen HJG: Total number of neurons and glial cells in human brain nuclei estimated by the disector and the fractionator. J Microsc 150:1-20, 1988
18. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR: Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2:595-610, 1987
19. Vahey JW, Lewis JL, Vanderby R Jr: Elastic moduli, yield stress, and ultimate stress of cancellous bone in the canine proximal femur. J Biomech 20:29-33, 1987
20. Vesterby A, Kragstrup J, Gundersen HJ, Melsen F: Unbiased stereologic estimation of surface density in bone using vertical sections. Bone 8:13-17, 1987
21. Whitehouse WJ: The quantitative morphology of anisotropic trabecular bone. J Microsc 101:153-168, 1974