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Volumn 507, Issue 3, 2001, Pages 288-294

GSK-3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and β-catenin stabilisation without elevation of glycogen synthase activity

(7) Culbert, Ainsley A a Brown, Murray J a Frame, Sheelagh b Hagen, Thilo a Cross, Darren A E a Bax, Benjamin a Reith, Alastair D a

a GLAXOSMITHKLINE (United Kingdom)

b UNIVERSITY OF DUNDEE (United Kingdom)

Author keywords

Catenin; FRAT1; Glycogen synthase kinase 3; Neuroprotection; PC12 cell; Tau

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; AXIN; BETA CATENIN; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3; PROTEIN FRAT1; TAU PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENOVIRUS; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN; CONTROLLED STUDY; DEPHOSPHORYLATION; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ADENOVIRIDAE; AMINOPHENOLS; ANIMALS; BETA CATENIN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARRIER PROTEINS; CYTOPLASM; CYTOSKELETAL PROTEINS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASES; INDOLES; MALEIMIDES; NEOPLASM PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; PC12 CELLS; PROTO-ONCOGENE PROTEINS; RATS; TAU PROTEINS; TRANS-ACTIVATORS;

ADENOVIRIDAE;

EID: 0035798069 PISSN: 00145793 EISSN: None Source Type: Journal
DOI: 10.1016/S0014-5793(01)02990-8 Document Type: Article

Times cited : (90)

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