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Volumn 22, Issue 6, 2011, Pages 595-604

Exogenous nucleosides modulate expression and activity of transcription factors in Caco-2 cells

Author keywords

Caco 2 cells; Exogenous nucleosides; Gene expression; Intestine; Transcription factors

Indexed keywords

GLUCOCORTICOID RECEPTOR; I KAPPA B; NUCLEOSIDE; PROTEIN CUX1; PROTEIN ETS1; PROTEIN P53; PROTEN SMAD 2; RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR 1;

EID: 79955874186     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2010.05.003     Document Type: Article
Times cited : (11)

References (52)
  • 1
    • 34547543603 scopus 로고    scopus 로고
    • Concentrative nucleoside transporters (CNTs) in epithelia: from absorption to cell signaling
    • Pastor-Anglada M., Errasti-Murugarren E., Aymerich I., Casado F.J. Concentrative nucleoside transporters (CNTs) in epithelia: from absorption to cell signaling. J Physiol Biochem 2007, 63:97-110.
    • (2007) J Physiol Biochem , vol.63 , pp. 97-110
    • Pastor-Anglada, M.1    Errasti-Murugarren, E.2    Aymerich, I.3    Casado, F.J.4
  • 2
    • 0028068683 scopus 로고
    • Role of nucleotides in intestinal development and repair: implications for infant nutrition
    • Uauy R., Quan R., Gil A. Role of nucleotides in intestinal development and repair: implications for infant nutrition. J Nutr 1994, 124:1436S-1441S.
    • (1994) J Nutr , vol.124
    • Uauy, R.1    Quan, R.2    Gil, A.3
  • 3
    • 0036050608 scopus 로고    scopus 로고
    • Modulation of the immune response mediated by dietary nucleotides
    • Gil A. Modulation of the immune response mediated by dietary nucleotides. Eur J Clin Nutr 2002, 56:S1-S4.
    • (2002) Eur J Clin Nutr , vol.56
    • Gil, A.1
  • 6
    • 0029136533 scopus 로고
    • The role of nucleotides in human nutrition
    • Carver J.D., Walker W.A. The role of nucleotides in human nutrition. J Nutr Biochem 1995, 6:58-72.
    • (1995) J Nutr Biochem , vol.6 , pp. 58-72
    • Carver, J.D.1    Walker, W.A.2
  • 7
    • 0028904066 scopus 로고
    • Maturation status of small intestine epithelium in rats deprived of dietary nucleotides
    • Ortega M.A., Gil A., Sanchez-Pozo A. Maturation status of small intestine epithelium in rats deprived of dietary nucleotides. Life Sci 1995, 56:1623-1630.
    • (1995) Life Sci , vol.56 , pp. 1623-1630
    • Ortega, M.A.1    Gil, A.2    Sanchez-Pozo, A.3
  • 8
    • 0029936901 scopus 로고    scopus 로고
    • Deprivation of dietary nucleotides decreases protein synthesis in the liver and small intestine in rats
    • Lopez-Navarro A.T., Ortega M.A., Peragón J., Bueno J.D., Gil A., Sanchez-Pozo A. Deprivation of dietary nucleotides decreases protein synthesis in the liver and small intestine in rats. Gastroenterology 1996, 110:1760-1769.
    • (1996) Gastroenterology , vol.110 , pp. 1760-1769
    • Lopez-Navarro, A.T.1    Ortega, M.A.2    Peragón, J.3    Bueno, J.D.4    Gil, A.5    Sanchez-Pozo, A.6
  • 9
    • 9244240758 scopus 로고    scopus 로고
    • Effect of dietary ribonucleotides on infant immune status. Part 2: immune cell development
    • Buck R.H., Thomas D.L., Winship T.R., Cordle C.T., Kuchan M.J., Baggs G.E., et al. Effect of dietary ribonucleotides on infant immune status. Part 2: immune cell development. Pediatr Res 2004, 56:891-900.
    • (2004) Pediatr Res , vol.56 , pp. 891-900
    • Buck, R.H.1    Thomas, D.L.2    Winship, T.R.3    Cordle, C.T.4    Kuchan, M.J.5    Baggs, G.E.6
  • 10
    • 1542327260 scopus 로고    scopus 로고
    • Dietary nucleotides and intestinal cell lines. I. Modulation of growth
    • Holen E., Jonsson R. Dietary nucleotides and intestinal cell lines. I. Modulation of growth. Nutr Res 2004, 24:197-207.
    • (2004) Nutr Res , vol.24 , pp. 197-207
    • Holen, E.1    Jonsson, R.2
  • 11
    • 33645373029 scopus 로고    scopus 로고
    • Effect of dietary nucleotide supplementation on growth and immune function in term infants: a randomized controlled trial
    • Hawkes J.S., Gibson R.A., Roberton D., Makrides M. Effect of dietary nucleotide supplementation on growth and immune function in term infants: a randomized controlled trial. Eur J Clin Nutr 2006, 60:254-264.
    • (2006) Eur J Clin Nutr , vol.60 , pp. 254-264
    • Hawkes, J.S.1    Gibson, R.A.2    Roberton, D.3    Makrides, M.4
  • 12
    • 0029020768 scopus 로고
    • Dietary nucleotides accelerate intestinal recovery after starvation in old rats
    • Ortega M.A., Núñez M.C., Gil A., Sanchez-Pozo A. Dietary nucleotides accelerate intestinal recovery after starvation in old rats. J Nutr 1995, 125:1413-1418.
    • (1995) J Nutr , vol.125 , pp. 1413-1418
    • Ortega, M.A.1    Núñez, M.C.2    Gil, A.3    Sanchez-Pozo, A.4
  • 13
    • 0030940361 scopus 로고    scopus 로고
    • Role of nucleosides and nucleotides in the immune system, gut reparation after injury, and brain function
    • Yamamoto S., Wang M.F., Adjei A.A., Ameho C.K. Role of nucleosides and nucleotides in the immune system, gut reparation after injury, and brain function. Nutrition 1997, 13:372-374.
    • (1997) Nutrition , vol.13 , pp. 372-374
    • Yamamoto, S.1    Wang, M.F.2    Adjei, A.A.3    Ameho, C.K.4
  • 15
    • 0036169925 scopus 로고    scopus 로고
    • Nucleotides as semiessential nutritional components
    • Sanchez-Pozo A., Gil A. Nucleotides as semiessential nutritional components. Br J Nutr 2002, 87:S135-S137.
    • (2002) Br J Nutr , vol.87
    • Sanchez-Pozo, A.1    Gil, A.2
  • 16
    • 30944465652 scopus 로고    scopus 로고
    • Gastroprotective effects of oral nucleotide administration
    • Belo A., Marchbank T., Fitzgerald A., Ghosh S., Playford R.J. Gastroprotective effects of oral nucleotide administration. Gut 2006, 55:165-171.
    • (2006) Gut , vol.55 , pp. 165-171
    • Belo, A.1    Marchbank, T.2    Fitzgerald, A.3    Ghosh, S.4    Playford, R.J.5
  • 17
    • 0027958121 scopus 로고
    • Nucleotide uptake and metabolism by intestinal epithelial cells
    • Sanderson I.R., He Y. Nucleotide uptake and metabolism by intestinal epithelial cells. J Nutr 1994, 124:131S-137S.
    • (1994) J Nutr , vol.124
    • Sanderson, I.R.1    He, Y.2
  • 18
    • 0029436297 scopus 로고
    • Gene expression in the intestine: the effect of dietary nucleotides
    • LeLeiko N.S., Walsh M.J., Abraham S. Gene expression in the intestine: the effect of dietary nucleotides. Adv Pediatr 1995, 42:145-169.
    • (1995) Adv Pediatr , vol.42 , pp. 145-169
    • LeLeiko, N.S.1    Walsh, M.J.2    Abraham, S.3
  • 19
    • 0030019770 scopus 로고    scopus 로고
    • Exogenous nucleotides alter the proliferation, differentiation and apoptosis of human small intestinal epithelium
    • Tanaka M., Lee K., Martinez-Augustin O., He Y., Sanderson I.R., Walker W.A. Exogenous nucleotides alter the proliferation, differentiation and apoptosis of human small intestinal epithelium. J Nutr 1996, 126:424-433.
    • (1996) J Nutr , vol.126 , pp. 424-433
    • Tanaka, M.1    Lee, K.2    Martinez-Augustin, O.3    He, Y.4    Sanderson, I.R.5    Walker, W.A.6
  • 20
    • 0034252218 scopus 로고    scopus 로고
    • Nucleotide and nucleoside supplementation may morphologically promote the differentiation of human caco-2 cells
    • Sato N., Kawakami H., Idota A. Nucleotide and nucleoside supplementation may morphologically promote the differentiation of human caco-2 cells. J Nutr Sci Vitaminol 2000, 46:175-179.
    • (2000) J Nutr Sci Vitaminol , vol.46 , pp. 175-179
    • Sato, N.1    Kawakami, H.2    Idota, A.3
  • 21
    • 1242342230 scopus 로고    scopus 로고
    • Exogenous nucleosides modulate the expression of rat liver extracellular matrix genes in single cultures of primary hepatocytes and a liver stellate cell line and in their co-culture
    • Arnaud A., Fontana L., Sáez-Lara M.J., Gil A., López-Pedrosa J.M. Exogenous nucleosides modulate the expression of rat liver extracellular matrix genes in single cultures of primary hepatocytes and a liver stellate cell line and in their co-culture. Clin Nutr 2004, 23:43-51.
    • (2004) Clin Nutr , vol.23 , pp. 43-51
    • Arnaud, A.1    Fontana, L.2    Sáez-Lara, M.J.3    Gil, A.4    López-Pedrosa, J.M.5
  • 22
  • 23
    • 0033058435 scopus 로고    scopus 로고
    • Nucleoside transport in human colonic epithelial cell lines: evidence for two Na+-independent transport systems in T84 and Caco-2 cells
    • Ward J.L., Tse C.M. Nucleoside transport in human colonic epithelial cell lines: evidence for two Na+-independent transport systems in T84 and Caco-2 cells. Biochim Biophys Acta 1999, 1419:15-22.
    • (1999) Biochim Biophys Acta , vol.1419 , pp. 15-22
    • Ward, J.L.1    Tse, C.M.2
  • 25
    • 0035951808 scopus 로고    scopus 로고
    • Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib)
    • Ritzel M.W., Ng A.M., Yao S.Y., Graham K., Loewen S.K., Smith K.M., et al. Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib). J Biol Chem 2001, 276:2914-2927.
    • (2001) J Biol Chem , vol.276 , pp. 2914-2927
    • Ritzel, M.W.1    Ng, A.M.2    Yao, S.Y.3    Graham, K.4    Loewen, S.K.5    Smith, K.M.6
  • 26
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • Research0034
    • Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002, 3:1-11. Research0034.
    • (2002) Genome Biol , vol.3 , pp. 1-11
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6
  • 27
    • 0034689773 scopus 로고    scopus 로고
    • Role of NF-kappa-B in p53-mediated programmed cell death
    • Ryan K.M., Ernst M.K., Rice N.R., Vousden K.H. Role of NF-kappa-B in p53-mediated programmed cell death. Nature 2000, 404:892-897.
    • (2000) Nature , vol.404 , pp. 892-897
    • Ryan, K.M.1    Ernst, M.K.2    Rice, N.R.3    Vousden, K.H.4
  • 28
    • 0028948866 scopus 로고
    • E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle
    • Sardet C., Vidal M., Cobrinik D., Geng Y., Onufryk C., Chen A., et al. E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proc Natl Acad Sci U S A 1995, 92:2403-2407.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 2403-2407
    • Sardet, C.1    Vidal, M.2    Cobrinik, D.3    Geng, Y.4    Onufryk, C.5    Chen, A.6
  • 31
    • 0025362367 scopus 로고
    • A regulatory element is characterized by purine-mediated and cell-type-specific gene transcription
    • Walsh M.J., Sanchez-Pozo A., Leleiko N.S. A regulatory element is characterized by purine-mediated and cell-type-specific gene transcription. Mol Cell Biol 1990, 10:4356-4364.
    • (1990) Mol Cell Biol , vol.10 , pp. 4356-4364
    • Walsh, M.J.1    Sanchez-Pozo, A.2    Leleiko, N.S.3
  • 32
    • 0029593552 scopus 로고
    • Dietary purine nucleotides and the gastrointestinal tract
    • Leleiko N.S., Walsh M.J. Dietary purine nucleotides and the gastrointestinal tract. Nutrition 1995, 11:725-730.
    • (1995) Nutrition , vol.11 , pp. 725-730
    • Leleiko, N.S.1    Walsh, M.J.2
  • 33
    • 0026445509 scopus 로고
    • Multiple in vivo footprints are specific to the active allele of the X-linked human hypoxanthine phosphoribosyltransferase gene 5' region: implications for X chromosome inactivation
    • Hornstra I.K., Yang T.P. Multiple in vivo footprints are specific to the active allele of the X-linked human hypoxanthine phosphoribosyltransferase gene 5' region: implications for X chromosome inactivation. Mol Cell Biol 1992, 12:5345-5354.
    • (1992) Mol Cell Biol , vol.12 , pp. 5345-5354
    • Hornstra, I.K.1    Yang, T.P.2
  • 34
    • 0038637214 scopus 로고    scopus 로고
    • Identification of an enhancer of the human activating protein-2-alpha gene that contains a critical Ets1 binding site
    • Cheng Y.H., Handwerger S. Identification of an enhancer of the human activating protein-2-alpha gene that contains a critical Ets1 binding site. J Clin Endocrinol Metab 2003, 88:3305-3311.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3305-3311
    • Cheng, Y.H.1    Handwerger, S.2
  • 36
    • 0027285314 scopus 로고
    • Nucleotide supplements alter proliferation and differentiation of cultured human (Caco-2) and rat (IEC-6) intestinal epithelial cells
    • He Y., Chu S.H., Walker W.A. Nucleotide supplements alter proliferation and differentiation of cultured human (Caco-2) and rat (IEC-6) intestinal epithelial cells. J Nutr 1993, 123:1017-1027.
    • (1993) J Nutr , vol.123 , pp. 1017-1027
    • He, Y.1    Chu, S.H.2    Walker, W.A.3
  • 37
    • 0026548252 scopus 로고
    • Expression, regulation, and chromosomal localization of the Max gene
    • Wagner A.J., Le Beau M.M., Diaz M.O., Hay N. Expression, regulation, and chromosomal localization of the Max gene. Proc Natl Acad Sci U S A 1992, 89:3111-3115.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 3111-3115
    • Wagner, A.J.1    Le Beau, M.M.2    Diaz, M.O.3    Hay, N.4
  • 38
    • 0022572014 scopus 로고
    • Alterations of myc, myb, and ras(Ha) proto-oncogenes in cancers are frequent and show clinical correlation
    • Yokota J., Tsunetsugu-Yokota Y., Battifora H., Le Fevre C., Cline M.J. Alterations of myc, myb, and ras(Ha) proto-oncogenes in cancers are frequent and show clinical correlation. Science 1986, 231:261-265.
    • (1986) Science , vol.231 , pp. 261-265
    • Yokota, J.1    Tsunetsugu-Yokota, Y.2    Battifora, H.3    Le Fevre, C.4    Cline, M.J.5
  • 39
    • 0742281300 scopus 로고    scopus 로고
    • E2F1 and c-Myc in cell growth and death
    • Matsumura I., Tanaka H., Kanakura Y. E2F1 and c-Myc in cell growth and death. Cell Cycle 2003, 2:333-338.
    • (2003) Cell Cycle , vol.2 , pp. 333-338
    • Matsumura, I.1    Tanaka, H.2    Kanakura, Y.3
  • 40
    • 53049092599 scopus 로고    scopus 로고
    • E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer
    • Ladu S., Calvisi D.F., Conner E.A., Farina M., Factor V.M., Thorgeirsson S.S. E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer. Gastroenterology 2008, 135:1322-1332.
    • (2008) Gastroenterology , vol.135 , pp. 1322-1332
    • Ladu, S.1    Calvisi, D.F.2    Conner, E.A.3    Farina, M.4    Factor, V.M.5    Thorgeirsson, S.S.6
  • 41
    • 0029909386 scopus 로고    scopus 로고
    • Transcription factor EGR-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor beta-1
    • Liu C., Adamson E., Mercola D. Transcription factor EGR-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor beta-1. Proc Natl Acad Sci U S A 1996, 93:11831-11836.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11831-11836
    • Liu, C.1    Adamson, E.2    Mercola, D.3
  • 42
    • 0033768824 scopus 로고    scopus 로고
    • Identification and characterization of constitutively active Smad2 mutants: evaluation of formation of Smad complex and subcellular distribution
    • Funaba M., Mathews L.S. Identification and characterization of constitutively active Smad2 mutants: evaluation of formation of Smad complex and subcellular distribution. Mol Endocr 2000, 14:1583-1591.
    • (2000) Mol Endocr , vol.14 , pp. 1583-1591
    • Funaba, M.1    Mathews, L.S.2
  • 43
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell J.E., Kerr I.M., Stark G.M. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264:1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell, J.E.1    Kerr, I.M.2    Stark, G.M.3
  • 44
    • 0038269009 scopus 로고    scopus 로고
    • Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease
    • Lovato P., Brender C., Agnholt J., Kelsen J., Kaltoft K., Svejgaard A., et al. Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease. J Biol Chem 2003, 278:16777-16781.
    • (2003) J Biol Chem , vol.278 , pp. 16777-16781
    • Lovato, P.1    Brender, C.2    Agnholt, J.3    Kelsen, J.4    Kaltoft, K.5    Svejgaard, A.6
  • 46
    • 0029900899 scopus 로고    scopus 로고
    • Reflections on STAT3, STAT5, and STAT6 as fat STATs
    • Darnell J.E. Reflections on STAT3, STAT5, and STAT6 as fat STATs. Proc Natl Acad Sci U S A 1996, 93:6221-6224.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 6221-6224
    • Darnell, J.E.1
  • 47
    • 0030043836 scopus 로고    scopus 로고
    • Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB
    • Barton K., Muthusamy N., Chanyangam M., Fischer C., Clendenin C., Leiden J.M. Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB. Nature 1996, 379:81-85.
    • (1996) Nature , vol.379 , pp. 81-85
    • Barton, K.1    Muthusamy, N.2    Chanyangam, M.3    Fischer, C.4    Clendenin, C.5    Leiden, J.M.6
  • 48
    • 0032589689 scopus 로고    scopus 로고
    • Activation of PPARgamma coactivator-1 through transcription factor docking
    • Puigserver P., Adelmant G., Wu Z., Fan M., Xu J., O'Malley B., et al. Activation of PPARgamma coactivator-1 through transcription factor docking. Science 1999, 286:1368-1371.
    • (1999) Science , vol.286 , pp. 1368-1371
    • Puigserver, P.1    Adelmant, G.2    Wu, Z.3    Fan, M.4    Xu, J.5    O'Malley, B.6
  • 49
    • 0027267344 scopus 로고
    • Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2
    • Peters L.L., Andrews N.C., Eicher E.M., Davidson M.B., Orkin S.H., Lux S.E. Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2. Nature 1993, 362:768-770.
    • (1993) Nature , vol.362 , pp. 768-770
    • Peters, L.L.1    Andrews, N.C.2    Eicher, E.M.3    Davidson, M.B.4    Orkin, S.H.5    Lux, S.E.6
  • 51
    • 0027965294 scopus 로고
    • Sp1-mediated transcriptional activation is repressed by Sp3
    • Hagen G., Muller S., Beato M., Suske G. Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J 1994, 13:3843-3851.
    • (1994) EMBO J , vol.13 , pp. 3843-3851
    • Hagen, G.1    Muller, S.2    Beato, M.3    Suske, G.4


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