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Volumn 300, Issue 5, 2011, Pages

Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility

Author keywords

Contraction; Hydrogen peroxide; Mammalian target of rapamycin; Smooth muscle

Indexed keywords

CALCINEURIN; CYCLOHEXIMIDE; CYCLOSPORIN A; DACTINOMYCIN; HYDROGEN PEROXIDE; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; PHENYLEPHRINE; POTASSIUM CHLORIDE; RAPAMYCIN; S6 KINASE; TACROLIMUS;

EID: 79955837051     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01084.2010     Document Type: Article
Times cited : (19)

References (50)
  • 2
    • 77953535497 scopus 로고    scopus 로고
    • Oxidative stress and hypertension: Current concepts
    • Briones AM, Touyz RM. Oxidative stress and hypertension: current concepts. Curr Hypertens Rep 12: 135-142, 2010.
    • (2010) Curr Hypertens Rep , vol.12 , pp. 135-142
    • Briones, A.M.1    Touyz, R.M.2
  • 3
    • 47249157776 scopus 로고    scopus 로고
    • Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling
    • Byon CH, Javed A, Dai Q, Kappes JC, Clemens TL, Darley-Usmar VM, McDonald JM, Chen Y. Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling. J Biol Chem 283: 15319-15327, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 15319-15327
    • Byon, C.H.1    Javed, A.2    Dai, Q.3    Kappes, J.C.4    Clemens, T.L.5    Darley-Usmar, V.M.6    McDonald, J.M.7    Chen, Y.8
  • 4
    • 0032531126 scopus 로고    scopus 로고
    • 2-treated young MRC5 fibroblasts correlates with increased glutathione peroxidase levels and resistance to DNA breakage
    • 2-treated young MRC5 fibroblasts correlates with increased glutathione peroxidase levels and resistance to DNA breakage. Mech Ageing Dev 105: 137-150, 1998.
    • (1998) Mech Ageing Dev , vol.105 , pp. 137-150
    • Caldini, R.1    Chevanne, M.2    Mocali, A.3    Tombaccini, D.4    Paoletti, F.5
  • 5
    • 0030784252 scopus 로고    scopus 로고
    • FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400 -1401) and anchors calcineurin to this FK506-like domain
    • Cameron AM, Nucifora FC Jr, Fung ET, Livingston DJ, Aldape RA, Ross CA, Snyder SH. FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400 -1401) and anchors calcineurin to this FK506-like domain. J Biol Chem 272: 27582-27588, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 27582-27588
    • Cameron, A.M.1    Nucifora Jr., F.C.2    Fung, E.T.3    Livingston, D.J.4    Aldape, R.A.5    Ross, C.A.6    Snyder, S.H.7
  • 7
    • 79955798211 scopus 로고    scopus 로고
    • Adventitia-derived hydrogen peroxide impairs relaxation of the rat carotid artery via smooth muscle cell p38 mitogenactivated protein kinase
    • Dec 2, Epub ahead of print
    • Cascino T, Csanyi G, Al Ghouleh I, Montezano AC, Touyz RM, Haurani MJ, Pagano PJ. Adventitia-derived hydrogen peroxide impairs relaxation of the rat carotid artery via smooth muscle cell p38 mitogenactivated protein kinase. Antioxid Redox Signal 2010 Dec 2. [Epub ahead of print].
    • (2010) Antioxid Redox Signal
    • Cascino, T.1    Csanyi, G.2    Al Ghouleh, I.3    Montezano, A.C.4    Touyz, R.M.5    Haurani, M.J.6    Pagano, P.J.7
  • 8
    • 41149116067 scopus 로고    scopus 로고
    • Possible role of oxidative stress in the pathogenesis of hypertension
    • Ceriello A. Possible role of oxidative stress in the pathogenesis of hypertension. Diabetes Care 31, Suppl 2: S181-S184, 2008.
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL. 2
    • Ceriello, A.1
  • 9
    • 21344440000 scopus 로고    scopus 로고
    • Reactive oxygen species as mediators of cellular senescence
    • Colavitti R, Finkel T. Reactive oxygen species as mediators of cellular senescence. IUBMB Life 57: 277-281, 2005.
    • (2005) IUBMB Life , vol.57 , pp. 277-281
    • Colavitti, R.1    Finkel, T.2
  • 10
    • 0037081770 scopus 로고    scopus 로고
    • Modulation of type-1 Ins(1,4,5)P3 receptor channels by the FK506-binding protein, FKBP12
    • Dargan SL, Lea EJ, Dawson AP. Modulation of type-1 Ins(1,4,5)P3 receptor channels by the FK506-binding protein, FKBP12. Biochem J 361: 401-407, 2002.
    • (2002) Biochem J , vol.361 , pp. 401-407
    • Dargan, S.L.1    Lea, E.J.2    Dawson, A.P.3
  • 11
    • 0037007014 scopus 로고    scopus 로고
    • FKBP12-rapamycin-associated protein associates with mitochondria Dysfunction senses osmotic stress via mitochondrial
    • Desai BN, Myers BR, Schreiber SL. FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction. Proc Natl Acad Sci USA 99: 4319-4324, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 4319-4324
    • Desai, B.N.1    Myers, B.R.2    Schreiber, S.L.3
  • 12
    • 77952749932 scopus 로고    scopus 로고
    • PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis
    • Faghiri Z, Bazan NG. PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis. Exp Eye Res 90: 718-725, 2010.
    • (2010) Exp Eye Res , vol.90 , pp. 718-725
    • Faghiri, Z.1    Bazan, N.G.2
  • 13
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 408: 239-247, 2000.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 14
    • 65949113601 scopus 로고    scopus 로고
    • Targeting mTOR with rapamycin: One dose does not fit all
    • Foster DA, Toschi A. Targeting mTOR with rapamycin: one dose does not fit all. Cell Cycle 8: 1026-1029, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 1026-1029
    • Foster, D.A.1    Toschi, A.2
  • 15
    • 72049117072 scopus 로고    scopus 로고
    • Mammalian target of rapamycin: Discovery of rapamycin reveals a signaling pathway important for normal and cancer cell growth
    • Gibbons JJ, Abraham RT, Yu K. Mammalian target of rapamycin: discovery of rapamycin reveals a signaling pathway important for normal and cancer cell growth. Semin Oncol 36, Suppl 3: S3-S17, 2009.
    • (2009) Semin Oncol , vol.36 , Issue.SUPPL. 3
    • Gibbons, J.J.1    Abraham, R.T.2    Yu, K.3
  • 16
    • 31944441800 scopus 로고    scopus 로고
    • 2-methoxyestradiol induces cell cycle arrest and mitotic cell apoptosis in human vascular smooth muscle cells
    • Gui Y, Zheng XL. 2-methoxyestradiol induces cell cycle arrest and mitotic cell apoptosis in human vascular smooth muscle cells. Hypertension 47: 271-280, 2006.
    • (2006) Hypertension , vol.47 , pp. 271-280
    • Gui, Y.1    Zheng, X.L.2
  • 19
    • 0032525349 scopus 로고    scopus 로고
    • 2 production of heart mitochondria and aging rate are slower in canaries and parakeets than in mice: Sites of free radical generation and mechanisms involved
    • 2 production of heart mitochondria and aging rate are slower in canaries and parakeets than in mice: sites of free radical generation and mechanisms involved. Mech Ageing Dev 103: 133-146, 1998.
    • (1998) Mech Ageing Dev , vol.103 , pp. 133-146
    • Herrero, A.1    Barja, G.2
  • 20
    • 0037108711 scopus 로고    scopus 로고
    • Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C
    • Huang C, Li J, Ke Q, Leonard SS, Jiang BH, Zhong XS, Costa M, Castranova V, Shi X. Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C. Cancer Res 62: 5689-5697, 2002.
    • (2002) Cancer Res , vol.62 , pp. 5689-5697
    • Huang, C.1    Li, J.2    Ke, Q.3    Leonard, S.S.4    Jiang, B.H.5    Zhong, X.S.6    Costa, M.7    Castranova, V.8    Shi, X.9
  • 21
    • 59749091850 scopus 로고    scopus 로고
    • A complex interplay between Akt, TSC2 and the two mTOR complexes
    • Huang J, Manning BD. A complex interplay between Akt, TSC2 and the two mTOR complexes. Biochem Soc Trans 37: 217-222, 2009.
    • (2009) Biochem Soc Trans , vol.37 , pp. 217-222
    • Huang, J.1    Manning, B.D.2
  • 22
    • 47949104258 scopus 로고    scopus 로고
    • Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling
    • Ikenoue T, Inoki K, Yang Q, Zhou X, Guan KL. Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling. EMBO J 27: 1919-1931, 2008.
    • (2008) EMBO J , vol.27 , pp. 1919-1931
    • Ikenoue, T.1    Inoki, K.2    Yang, Q.3    Zhou, X.4    Guan, K.L.5
  • 30
    • 65349104490 scopus 로고    scopus 로고
    • Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy
    • McCrann DJ, Yang D, Chen H, Carroll S, Ravid K. Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy. Cell Cycle 8: 902-908, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 902-908
    • McCrann, D.J.1    Yang, D.2    Chen, H.3    Carroll, S.4    Ravid, K.5
  • 31
    • 33845609865 scopus 로고    scopus 로고
    • Mutual antagonism of target of rapamycin and calcineurin signaling
    • Mulet JM, Martin DE, Loewith R, Hall MN. Mutual antagonism of target of rapamycin and calcineurin signaling. J Biol Chem 281: 33000-33007, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 33000-33007
    • Mulet, J.M.1    Martin, D.E.2    Loewith, R.3    Hall, M.N.4
  • 34
    • 0037452972 scopus 로고    scopus 로고
    • Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PI3K and Akt
    • Qin S, Chock PB. Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PI3K and Akt. Biochemistry 42: 2995-3003, 2003.
    • (2003) Biochemistry , vol.42 , pp. 2995-3003
    • Qin, S.1    Chock, P.B.2
  • 38
    • 64049100188 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation
    • Sadidi M, Lentz SI, Feldman EL. Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation. Biochimie 91: 577-585, 2009.
    • (2009) Biochimie , vol.91 , pp. 577-585
    • Sadidi, M.1    Lentz, S.I.2    Feldman, E.L.3
  • 40
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307: 1098- 1101, 2005.
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 41
    • 77954671837 scopus 로고    scopus 로고
    • Vascular aging: From molecular mechanism to clinical significance
    • Sawabe M. Vascular aging: from molecular mechanism to clinical significance. Geriatr Gerontol Int 10 Suppl 1: S213-S220, 2010.
    • (2010) Geriatr Gerontol Int 10 Suppl , vol.10 , Issue.SUPPL. 1
    • Sawabe, M.1
  • 42
    • 0025943770 scopus 로고
    • Hydrogen peroxide production by mitochondria may be a biomarker of aging
    • Sohal RS. Hydrogen peroxide production by mitochondria may be a biomarker of aging. Mech Ageing Dev 60: 189-198, 1991.
    • (1991) Mech Ageing Dev , vol.60 , pp. 189-198
    • Sohal, R.S.1
  • 43
    • 0028268734 scopus 로고
    • Mitochondrial oxidative damage, hydrogen peroxide release, and aging
    • Sohal RS, Dubey A. Mitochondrial oxidative damage, hydrogen peroxide release, and aging. Free Radic Biol Med 16: 621-626, 1994.
    • (1994) Free Radic Biol Med , vol.16 , pp. 621-626
    • Sohal, R.S.1    Dubey, A.2
  • 44
    • 77954235821 scopus 로고    scopus 로고
    • Targeting mTOR: Prospects for mTOR complex 2 inhibitors in cancer therapy
    • Sparks CA, Guertin DA. Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy. Oncogene 29: 3733-3744, 2010.
    • (2010) Oncogene , vol.29 , pp. 3733-3744
    • Sparks, C.A.1    Guertin, D.A.2
  • 45
    • 0027028294 scopus 로고
    • Recent advances in the mechanism of action of cyclosporine and FK506
    • Tocci MJ, Sigal NH. Recent advances in the mechanism of action of cyclosporine and FK506. Curr Opin Nephrol Hypertens 1: 236-242, 1992.
    • (1992) Curr Opin Nephrol Hypertens , vol.1 , pp. 236-242
    • Tocci, M.J.1    Sigal, N.H.2
  • 48
    • 0034678050 scopus 로고    scopus 로고
    • Homocysteine accelerates endothelial cell senescence
    • Xu D, Neville R, Finkel T. Homocysteine accelerates endothelial cell senescence. FEBS Lett 470: 20-24, 2000.
    • (2000) FEBS Lett , vol.470 , pp. 20-24
    • Xu, D.1    Neville, R.2    Finkel, T.3
  • 49
    • 0033396236 scopus 로고    scopus 로고
    • Hydrogen peroxide induces contraction and raises [Ca2+]i in canine cerebral arterial smooth muscle: Participation of cellular signaling pathways
    • Yang ZW, Zheng T, Wang J, Zhang A, Altura BT, Altura BM. Hydrogen peroxide induces contraction and raises [Ca2+]i in canine cerebral arterial smooth muscle: participation of cellular signaling pathways. Naunyn Schmiedebergs Arch Pharmacol 360: 646-653, 1999.
    • (1999) Naunyn Schmiedebergs Arch Pharmacol , vol.360 , pp. 646-653
    • Yang, Z.W.1    Zheng, T.2    Wang, J.3    Zhang, A.4    Altura, B.T.5    Altura, B.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.