PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis

Experimental Eye Research

Volumn 90, Issue 6, 2010, Pages 718-725

  Faghiri, Zahra ^a   Bazan, Nicolas G ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID DERIVATIVE; HYDROGEN PEROXIDE; MAMMALIAN TARGET OF RAPAMYCIN; NEUROPROTECTIN D1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANDROSTANE DERIVATIVE; DOCOSAHEXAENOIC ACID; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN; SIGNAL PEPTIDE; WORTMANNIN;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; INCUBATION TIME; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; CELL LINE; CONFOCAL MICROSCOPY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG COMBINATION; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; HYDROGEN PEROXIDE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROSCOPY, CONFOCAL; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RETINAL PIGMENT EPITHELIUM; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIROLIMUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77952749932     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2010.03.002     Document Type: Article

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