Hydrogen peroxide mediates arsenite activation of p70s6k and extracellular signal-regulated kinase

Experimental Cell Research

Volumn 290, Issue 1, 2003, Pages 144-154

  Jung, Dong Keun ^a   Bae, Gyu Un ^a   Kim, Yong Kee ^a   Han, Seung Hee ^a   Choi, Wahn Soo ^b   Kang, Hyeog ^c   Seo, Dong Wan ^d   Lee, Hoi Young ^e   Cho, Eun Jung ^a   Lee, Hyang Woo ^a   Han, Jeung Whan ^a  

^a Sungkyunkwan University   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e Konyang University   (South Korea)

Author keywords

Arsenite; Extracellular signal regulated kinase 1 2; H2O2; p70s6k

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLCYSTEINE; ARSENIC TRIOXIDE; CALCIUM CHELATING AGENT; CATALASE; DICHLOROFLUORESCEIN; FLUORESCEIN DERIVATIVE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; S6 KINASE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; EPIDERMIS CELL; FLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; SIGNAL TRANSDUCTION; TUMOR PROMOTION;

EID: 0141457589     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4827(03)00320-3     Document Type: Article

References (61)

1. Snow E.T. Metal carcinogenesis mechanistic implications, Pharmacol . Ther. 53:1992;31-65.
2. Bagla P., Kaiser J. India's spreading health crisis draws global arsenic experts. Science 274. 1996;174-175.
3. Bettley F.R., O'Shea J. The absorption of arsenic and its relation to carcinoma. Br. J. Dermatol. 92:1975;563-568.
4. Cuzick J., Evans S., Gillman M., Price Evans D.A. Medicinal arsenic and internal malignancies. Br. J. Cancer. 45:1982;904-911.
5. Germolec D.R., Yoshida T., Gaido K., Wilmer J.L., Simeonova P.P., Kayama F., Burleson F., Dong W., Lange R.W., Luster M.I. Arsenic induces overexpression of growth factors in human keratinocytes. Toxicol. Appl. Pharmacol. 141:1996;308-318.
6. Tseng W.P., Chu M.M., How S.W. Prevalence of skin cancer in an endemic area of chronic arsenicism in Taiwan. J. Natl. Cancer Ins. 40:1968;453-463.
7. Hartwig A., Groblinghoff U.D., Beyersmann D., Natarajan A.T., Filon R., Mullenders L.H. Interaction of arsenic(III) with nucleotide excision repair in UV-irradiated human fibroblasts. Carcinogenesis. 18:1997;399-405.
8. Chang L., Karin M. Mammalian MAP kinase signaling cascades. Nature. 410:2001;37-40.
9. Clemens M.J., Bommer U.A. Translational control the cancer connection . Int. J. Biochem. Cell. Biol. 31:1999;1-23.
10. Davis R.J. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268:1993;14553-14556.
11. Morley S.J., Thomas G. Intracellular messengers and the control of protein synthesis. Pharmacol. Ther. 50:1991;291-319.
12. Fantl W.J., Johnson D.E., Williams L.T. Signalling by receptor tyrosine kinases. Annu. Rev. Biochem. 62:1993;453-481.
13. Heldin C.H. Dimerization of cell surface receptors in signal transduction. Cell. 80:1995;213-223.
14. Feig L.A. The many roads that lead to Ras. Science. 260:1993;767-768.
15. Schlessinger J. How receptor tyrosine kinases activate Ras. Trends Biochem. Sci. 18:1993;273-275.
16. Avruch J., Zhang X.F., Kyriakis J.M. Raf meets Ras completing the framework of a signal transduction pathway . Trends Biochem. Sci. 19:1994;279-283.
17. Ming X.F., Burgering B.M.T., Wennstrom S., Claesson-Welsh L., Heldin C.H., Bos J.L., Kozma S.C., Thomas G. Activation of p70/p85 S6 kinase by a pathway independent of p21ras. Nature. 371:1994;426-429.
18. Chung J., Grammer T., Lemon K.P., Kazlauskas A., Blenis J. PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase. Nature. 370:1994;71-75.
19. Weng Q.P., Andrabi K., Klippel A., Kozlowski M.T., Williams L.T., Avruch J. Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation. Proc. Natl. Acad. Sci. USA. 92:1995;5744-5748.
20. Downward J. Signal transduction a target for PI(3) kinase . Nature. 376:1995;553-554.
21. Kitamura T., Ogawa W., Sakaue H., Hino Y., Kuroda S., Takata M., Matsumoto M., Maeda T., Konishi H., Kikkawa U., Kasuga M. Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport. Mol. Cell. Biol. 18:1998;3708-3717.
22. Cheatham B., Vlahos C.J., Cheatham L., Wang L., Blenis J., Kahn C.R. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol. Cell. Biol. 14:1994;4902-4911.
23. Andjelkovic M., Jakubowicz T., Cron P., Ming X.-F., Han J.W., Hemmings B.A. Activation and phosphorylation of a pleokstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors. Proc. Natl. Acad. Sci. USA. 93:1996;5699-5704.
24. Conus N.M., Hemmings B.A., Pearson R.B. Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k. J. Biol. Chem. 273:1998;4776-4782.
25. Stewart M.J., Thomas G. Mitogenesis and protein synthesis a role for ribosomal protein S6 phosphorylation? BioEssay. 16:1994;809-815.
26. Jefferies H.B., Reinhard C., Kozma S.C., Thomas G. Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family. Proc. Natl. Acad. Sci. USA. 91:1994;4441-4445.
27. Jefferies H.B., Thomas G., Thomas G. Elongation factor-1 alpha mRNA is selectively translated following mitogenic stimulation. J. Biol. Chem. 269:1994;4367-4372.
28. Cowley S., Paterson H., Kemp P., Marshall C.J. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell. 77:1994;841-852.
29. s6k phosphorylation, cell proliferation, and colony formation in small cell lung cancer cells. Cancer Res. 56:1996;3895-3897.
30. Lengyel E., Wang H., Gum R., Simon C., Wang Y., Boyd D. Elevated urokinase-type plasminogen activator receptor expression in a colon cancer cell line is due to a constitutively activated extracellular signal-regulated kinase-1-dependent signaling cascade. Oncogene. 14:1997;2563-2573.
31. Schmidt C.M., McKillop I.H., Cahill P.A., Sitzmann J.V. Increased MAPK expression and activity in primary human hepatocellular carcinoma. Biochem. Biophys. Res. Commun. 236:1997;54-58.
32. 2 on protein tyrosine phosphatase activity in HER14 cells. Free Radical Biol. Med. 16:1994;399-403.
33. 2 for platelet-derived growth factor signal transduction. Science. 270:1995;296-299.
34. S6k signaling pathway. J. Biol. Chem. 274:1999;32596-32602.
35. Manna S.K., Zhang H.J., Yan T., Oberley L.W., Aggarwal B.B. Overexpression of manganese superoxide dismutase. suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1. J. Biol. Chem. 273:1998;13245-13254.
36. Schreck R., Rieber P., Baeuerle P.A. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 10:1991;2247-2258.
37. Lo Y.Y.C., Cruz T.F. Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes. J. Biol. Chem. 270:1995;11727-11730.
38. 2 role in cell survival following oxidant injury . J. Biol. Chem. 271:1996;4138-4142.
39. 2-terminal kinases. J. Biol. Chem. 271:1996;15703-15707.
40. Chen W., Martindale J.L., Holbrook N.J., Liu Y. Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc. Mol. Cell. Biol. 18:1998;5178-5188.
41. Wang X., Proud C.G. p70 S6 kinase is activated by sodium arsenite in adult rat cardiomyocytes roles for phosphatidylinositol 3-kinase and p38 MAP kinase . Biochem. Biophys. Res. Commun. 238:1997;207-212.
42. Duyndam M.C., Hulscher T.M., Fontijn D., Pinedo H.M., Boven E. Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1 alpha protein by the oxidative stressor arsenite. J. Biol. Chem. 276:2001;48066-48076.
43. Ozaki M., Deshpande S.S., Angkeow P., Suzuki S., Irani K. Rac1 regulates stress-induced, redox-dependent heat shock factor activation. J. Biol. Chem. 275:2000;35377-35383.
44. Huang C., Ma W.Y., Li J., Goranson A., Dong Z. Requirement of Erk, but not JNK, for arsenite-induced cell transformation. J. Biol. Chem. 274:1999;14595-14601.
45. Susa M., Olivier A.R., Fabbro D., Thomas G. EGF induces biphasic S6 kinase activation late phase is protein kinase C-dependent and contributes to mitogenicity . Cell. 57:1989;817-824.
46. Moldeus P., Cotgreave I.A., Berggren M. Lung protection by a thiol-containing antioxidant N-acetylcysteine . Respiration. 50:1986;31-42.
47. Huang C., Ma W.Y., Ryan C.A., Dong Z. Proteinase inhibitors I and II from potatoes specifically block UV-induced activator protein-1 activation through a pathway that is independent of extracellular signal-regulated kinases, c-Jun N-terminal kinases, and P38 kinase. Proc. Natl. Acad. Sci. USA. 94:1997;11957-11962.
48. Graves L.M., He Y., Lambert J., Hunter D., Li X., Earp H.S. An intracellular calcium signal activates p70 but not p90 ribosomal S6 kinase in liver epithelial cells. J. Biol. Chem. 272:1997;1920-1928.
49. Shah B.H., Catt K.J. Calcium-independent activation of extracellularly regulated kinases 1 and 2 by angiotensin II in hepatic C9 cells roles of protein kinase Cdelta, Src/proline-rich tyrosine kinase 2, and epidermal growth receptor trans-activation . Mol. Pharmacol. 61:2002;343-351.
50. Eguchi S., Iwasaki H., Ueno H., Frank G.D., Motley E.D., Eguchi K., Marumo F., Hirata Y., Inagami T. Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt . J. Biol. Chem. 274:1999;36843-36851.
51. 2 in Rat-2 fibroblasts. J. Biol. Chem. 273:1998;12710-12715.
52. 2 production requires the activation of phosphatidylinositol 3-kinase. J. Biol. Chem. 275:2000;10527-10531.
53. Tu V.C., Bahl J.J., Chen Q.M. Signals of oxidant-induced cardiomyocyte hypertrophy key activation of p70 S6 kinase-1 and phosphoinositide 3-kinase . J. Pharmacol. Exp. Ther. 300:2002;1101-1110.
54. Cavigelli M., Li W.W., Lin A., Su B., Yoshioka K., Karin M. The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase. EMBO J. 15:1996;6269-6279.
55. Dérijard B., Hibi M., Wu I.H., Barrett T., Su B., Deng T., Karin M., Davis R.J. JNK1 a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain . Cell. 76:1994;1025-1037.
56. Suzuki Y.J., Forman H.J., Sevanian A. Oxidants as stimulators of signal transduction. Free Radical Biol. Med. 22:1997;269-285.
57. Simeonova P.P., Wang S., Hulderman T., Luster M.I. c-Src-dependent activation of the epidermal growth factor receptor and mitogen-activated protein kinase pathway by arsenic role in carcinogenesis . J. Biol. Chem. 277:2002;2945-2950.
58. s6k function is essential for G1 progression. Nature. 363:1993;170-172.
59. Lansdown A.B.G. Physiological and toxicological changes in the skin resulting from the action and interaction of metal ions. Crit. Rev. Toxicol. 25:1995;397-462.
60. Zhao C.Q., Young M.R., Diwan B.A., Coogan T.P., Waalkes M.P. Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Proc. Natl. Acad. Sci. USA. 94:1997;10907-10912.
61. Simeonova P.P., Wang S., Toriuma W., Kommineni V., Matheson J., Unimye N., Kayama F., Harki D., Ding M., Vallyathan V., Luster M.I. Arsenic mediates cell proliferation and gene expression in the bladder epithelium association with activating protein-1 transactivation . Cancer Res. 60:2000;3445-3453.