Synergic effects of β-estradiol and erythromycin on hERG currents

Journal of Membrane Biology

Volumn 241, Issue 1, 2011, Pages 31-38

  Ando, Fumiaki ^a,b   Kuruma, Akinori ^c,d   Kawano, Seiko ^a,e  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN TAMA MEDICAL CENTER   (Japan)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^d NIPPON MEDICAL SCHOOL   (Japan)

^e KOMAZAWA WOMEN'S UNIVERSITY   (Japan)

Author keywords

Estradiol; Erythromycin; hERG current; Ikr; Patch clamp; QT prolongation; Sex hormone

Indexed keywords

ERYTHROMYCIN; ESTRADIOL; POTASSIUM CHANNEL HERG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; EMBRYO; HORMONAL REGULATION; HUMAN; HUMAN CELL; IC 50; INTRACELLULAR SIGNALING; KIDNEY CELL; PROTEIN EXPRESSION; QT PROLONGATION; SEX DIFFERENCE;

ELECTROPHYSIOLOGY; ERYTHROMYCIN; ESTRADIOL; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; HEK293 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MALE; PATCH-CLAMP TECHNIQUES;

EID: 79955684785     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-011-9360-z     Document Type: Article

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