Block of HERG current expressed in HEK293 cells by the Na+-channel blocker cibenzoline

Heart and Vessels

Volumn 19, Issue 3, 2004, Pages 137-143

  Hiramatsu, Mikio ^a   Wu, Long Mei ^a   Hirano, Yuji ^a   Kawano, Seiko ^a   Furukawa, Tetsushi ^a   Hiraoka, Masayasu ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Action potential duration; HERG channel; Open state of channel; QT prolongation; Rapidly activating component of potassium current

Indexed keywords

CIBENZOLINE; INWARDLY RECTIFYING POTASSIUM CHANNEL; POTASSIUM; POTASSIUM CHANNEL HERG; SODIUM; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; VOLTAGE GATED POTASSIUM CHANNEL;

ANTIARRHYTHMIC ACTIVITY; ARTICLE; BINDING SITE; CONTROLLED STUDY; DEPOLARIZATION; GENETIC CODE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; STEADY STATE;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; CELL LINE; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; IMIDAZOLES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SODIUM CHANNEL BLOCKERS; TRANSFECTION;

EID: 3042520609     PISSN: 09108327     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00380-003-0750-8     Document Type: Article

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