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Volumn 25, Issue 7, 2011, Pages 1281-1289

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures

Author keywords

Anticonvulsant; DAMPs; Epilepsy; Interleukins; LPS; PAMPs

Indexed keywords

ANTIINFLAMMATORY AGENT; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; TOLL LIKE RECEPTOR;

EID: 79955681780     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2011.03.018     Document Type: Review
Times cited : (333)

References (92)
  • 1
    • 0032078325 scopus 로고    scopus 로고
    • The interleukin-1 system: receptors, ligands, and ICE in the brain and their involvement in the fever response
    • Alheim K., Bartfai T. The interleukin-1 system: receptors, ligands, and ICE in the brain and their involvement in the fever response. Ann. N. Y. Acad. Sci. 1998, 840:51-58.
    • (1998) Ann. N. Y. Acad. Sci. , vol.840 , pp. 51-58
    • Alheim, K.1    Bartfai, T.2
  • 3
    • 77955845563 scopus 로고    scopus 로고
    • Inflammation enhances epileptogenesis in the developing rat brain
    • Auvin S., Mazarati A., Shin D., Sankar R. Inflammation enhances epileptogenesis in the developing rat brain. Neurobiol. Dis. 2010, 40:303-310.
    • (2010) Neurobiol. Dis. , vol.40 , pp. 303-310
    • Auvin, S.1    Mazarati, A.2    Shin, D.3    Sankar, R.4
  • 4
    • 58149105502 scopus 로고    scopus 로고
    • A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1beta
    • Balosso S., Maroso M., Sanchez-Alavez M., Ravizza T., Frasca A., Bartfai T., Vezzani A. A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1beta. Brain 2008, 131:3256-3265.
    • (2008) Brain , vol.131 , pp. 3256-3265
    • Balosso, S.1    Maroso, M.2    Sanchez-Alavez, M.3    Ravizza, T.4    Frasca, A.5    Bartfai, T.6    Vezzani, A.7
  • 5
    • 0025878385 scopus 로고
    • Receptors for interleukin-1 (alpha and beta) in mouse brain: mapping and neuronal localization in hippocampus
    • Ban E., Milon G., Prudhomme N., Fillion G., Haour F. Receptors for interleukin-1 (alpha and beta) in mouse brain: mapping and neuronal localization in hippocampus. Neuroscience 1991, 43:21-30.
    • (1991) Neuroscience , vol.43 , pp. 21-30
    • Ban, E.1    Milon, G.2    Prudhomme, N.3    Fillion, G.4    Haour, F.5
  • 6
    • 0024849292 scopus 로고
    • Bidirectional transport of interleukin-1 alpha across the blood-brain barrier
    • Banks W.A., Kastin A.J., Durham D.A. Bidirectional transport of interleukin-1 alpha across the blood-brain barrier. Brain Res. Bull. 1989, 23:433-437.
    • (1989) Brain Res. Bull. , vol.23 , pp. 433-437
    • Banks, W.A.1    Kastin, A.J.2    Durham, D.A.3
  • 8
    • 0033952703 scopus 로고    scopus 로고
    • Tlr4: central component of the sole mammalian LPS sensor
    • Beutler B. Tlr4: central component of the sole mammalian LPS sensor. Curr. Opin. Immunol. 2000, 12:20-26.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 20-26
    • Beutler, B.1
  • 9
    • 3142654210 scopus 로고    scopus 로고
    • Inferences, questions and possibilities in Toll-like receptor signalling
    • Beutler B. Inferences, questions and possibilities in Toll-like receptor signalling. Nature 2004, 430:257-263.
    • (2004) Nature , vol.430 , pp. 257-263
    • Beutler, B.1
  • 10
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: all we need to know about danger
    • Bianchi M.E. DAMPs, PAMPs and alarmins: all we need to know about danger. J. Leukoc. Biol. 2007, 81:1-5.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 11
    • 0036841178 scopus 로고    scopus 로고
    • Broad expression of Toll-like receptors in the human central nervous system
    • Bsibsi M., Ravid R., Gveric D., van Noort J.M. Broad expression of Toll-like receptors in the human central nervous system. J. Neuropathol. Exp. Neurol. 2002, 61:1013-1021.
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 1013-1021
    • Bsibsi, M.1    Ravid, R.2    Gveric, D.3    van Noort, J.M.4
  • 12
    • 70349329704 scopus 로고    scopus 로고
    • The blood-brain barrier in neurodegenerative disease: a rhetorical perspective
    • Carvey P.M., Hendey B., Monahan A.J. The blood-brain barrier in neurodegenerative disease: a rhetorical perspective. J. Neurochem. 2009, 111:291-314.
    • (2009) J. Neurochem. , vol.111 , pp. 291-314
    • Carvey, P.M.1    Hendey, B.2    Monahan, A.J.3
  • 13
    • 14044279966 scopus 로고    scopus 로고
    • Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines
    • Chakravarty S., Herkenham M. Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines. J. Neurosci. 2005, 25:1788-1796.
    • (2005) J. Neurosci. , vol.25 , pp. 1788-1796
    • Chakravarty, S.1    Herkenham, M.2
  • 15
    • 0032989434 scopus 로고    scopus 로고
    • Converting enzyme-independent release of tumor necrosis factor α and IL-1β from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3
    • Coeshott C., Ohnemus C., Pilyavskaya A., Ross S., Wieczorek M., Kroona H., Leimer A.H., Cheronis J. Converting enzyme-independent release of tumor necrosis factor α and IL-1β from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3. Proc. Natl. Acad. Sci. USA 1999, 96:6261-6266.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6261-6266
    • Coeshott, C.1    Ohnemus, C.2    Pilyavskaya, A.3    Ross, S.4    Wieczorek, M.5    Kroona, H.6    Leimer, A.H.7    Cheronis, J.8
  • 16
    • 33644523710 scopus 로고    scopus 로고
    • MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics
    • Davis C.N., Mann E., Behrens M.M., Gaidarova S., Rebek M., Rebek J., Bartfai T. MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics. Proc. Natl. Acad. Sci. USA 2006, 103:2953-2958.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2953-2958
    • Davis, C.N.1    Mann, E.2    Behrens, M.M.3    Gaidarova, S.4    Rebek, M.5    Rebek, J.6    Bartfai, T.7
  • 17
    • 33746927145 scopus 로고    scopus 로고
    • IL-1beta induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons
    • Davis C.N., Tabarean I., Gaidarova S., Behrens M.M., Bartfai T. IL-1beta induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons. J. Neurochem. 2006, 98:1379-1389.
    • (2006) J. Neurochem. , vol.98 , pp. 1379-1389
    • Davis, C.N.1    Tabarean, I.2    Gaidarova, S.3    Behrens, M.M.4    Bartfai, T.5
  • 19
    • 0037396704 scopus 로고    scopus 로고
    • Interleukin-1 beta protects neurons via the interleukin-1 (IL-1) receptor-mediated Akt pathway and by IL-1 receptor-independent decrease of transmembrane currents in vivo
    • Diem R., Hobom M., Grotsch P., Kramer B., Bahr M. Interleukin-1 beta protects neurons via the interleukin-1 (IL-1) receptor-mediated Akt pathway and by IL-1 receptor-independent decrease of transmembrane currents in vivo. Mol. Cell. Neurosci. 2003, 22:487-500.
    • (2003) Mol. Cell. Neurosci. , vol.22 , pp. 487-500
    • Diem, R.1    Hobom, M.2    Grotsch, P.3    Kramer, B.4    Bahr, M.5
  • 20
    • 79953813107 scopus 로고    scopus 로고
    • Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
    • Dinarello C.A. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 2011, 117:3720-3732.
    • (2011) Blood , vol.117 , pp. 3720-3732
    • Dinarello, C.A.1
  • 22
    • 0032528102 scopus 로고    scopus 로고
    • Kainic acid induced expression of interleukin-1 receptor antagonist mRNA in the rat brain
    • Eriksson C., Winblad B., Schultzberg M. Kainic acid induced expression of interleukin-1 receptor antagonist mRNA in the rat brain. Brain Res. Mol. Brain Res. 1998, 58:195-208.
    • (1998) Brain Res. Mol. Brain Res. , vol.58 , pp. 195-208
    • Eriksson, C.1    Winblad, B.2    Schultzberg, M.3
  • 23
    • 0037629646 scopus 로고    scopus 로고
    • PI3K and negative regulation of TLR signaling
    • Fukao T., Koyasu S. PI3K and negative regulation of TLR signaling. Trends Immunol. 2003, 24:358-363.
    • (2003) Trends Immunol. , vol.24 , pp. 358-363
    • Fukao, T.1    Koyasu, S.2
  • 24
    • 70349774217 scopus 로고    scopus 로고
    • Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats
    • Galic M.A., Riazi K., Henderson A.K., Tsutsui S., Pittman Q.J. Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats. Neurobiol. Dis. 2009, 36:343-351.
    • (2009) Neurobiol. Dis. , vol.36 , pp. 343-351
    • Galic, M.A.1    Riazi, K.2    Henderson, A.K.3    Tsutsui, S.4    Pittman, Q.J.5
  • 25
    • 33744823520 scopus 로고    scopus 로고
    • Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis
    • Gibson F.C., Yumoto H., Takahashi Y., Chou H.H., Genco C.A. Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis. J. Dent. Res. 2006, 85:106-121.
    • (2006) J. Dent. Res. , vol.85 , pp. 106-121
    • Gibson, F.C.1    Yumoto, H.2    Takahashi, Y.3    Chou, H.H.4    Genco, C.A.5
  • 26
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • Glass C.K., Saijo K., Winner B., Marchetto M.C., Gage F.H. Mechanisms underlying inflammation in neurodegeneration. Cell 2010, 140:918-934.
    • (2010) Cell , vol.140 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 27
    • 0037006035 scopus 로고    scopus 로고
    • Protective effect of trans-resveratrol against kainic acid-induced seizures and oxidative stress in rats
    • Gupta Y.K., Briyal S., Chaudhary G. Protective effect of trans-resveratrol against kainic acid-induced seizures and oxidative stress in rats. Pharmacol. Biochem. Behav. 2002, 71:245-249.
    • (2002) Pharmacol. Biochem. Behav. , vol.71 , pp. 245-249
    • Gupta, Y.K.1    Briyal, S.2    Chaudhary, G.3
  • 28
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch U.K., Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat. Neurosci. 2007, 10:1387-1394.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 29
    • 0033854412 scopus 로고    scopus 로고
    • Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy
    • Henshall D.C., Clark R.S., Adelson P.D., Chen M., Watkins S.C., Simon R.P. Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy. Neurology 2000, 55:250-257.
    • (2000) Neurology , vol.55 , pp. 250-257
    • Henshall, D.C.1    Clark, R.S.2    Adelson, P.D.3    Chen, M.4    Watkins, S.C.5    Simon, R.P.6
  • 30
    • 0037069271 scopus 로고    scopus 로고
    • Epilepsy after brain insult: targeting epileptogenesis
    • Herman S.T. Epilepsy after brain insult: targeting epileptogenesis. Neurology 2002, 59:S21-S26.
    • (2002) Neurology , vol.59
    • Herman, S.T.1
  • 31
    • 1542285224 scopus 로고    scopus 로고
    • Amphoterin as an extracellular regulatior of cell motility: from discovery to disease
    • Huttunen H.J., Rauvala H. Amphoterin as an extracellular regulatior of cell motility: from discovery to disease. J. Inter. Med. 2004, 255:351-366.
    • (2004) J. Inter. Med. , vol.255 , pp. 351-366
    • Huttunen, H.J.1    Rauvala, H.2
  • 32
    • 77956318202 scopus 로고    scopus 로고
    • Evaluation of the innate and adaptive immunity in type I and type II focal cortical dysplasias
    • Iyer A., Zurolo E., Spliet W.G., van Rijen P.C., Baayen J.C., Gorter J.A., Aronica E. Evaluation of the innate and adaptive immunity in type I and type II focal cortical dysplasias. Epilepsia 2010, 51:1763-1773.
    • (2010) Epilepsia , vol.51 , pp. 1763-1773
    • Iyer, A.1    Zurolo, E.2    Spliet, W.G.3    van Rijen, P.C.4    Baayen, J.C.5    Gorter, J.A.6    Aronica, E.7
  • 35
    • 66249132320 scopus 로고    scopus 로고
    • Cyclooxygenase in epilepsy: from perception to application
    • Kulkarni S.K., Dhir A. Cyclooxygenase in epilepsy: from perception to application. Drugs Today (Barc) 2009, 45:135-154.
    • (2009) Drugs Today (Barc) , vol.45 , pp. 135-154
    • Kulkarni, S.K.1    Dhir, A.2
  • 36
    • 33646895170 scopus 로고    scopus 로고
    • Interleukin-1 beta modulates AMPA receptor expression and phosphorylation in hippocampal neurons
    • Lai A.Y., Swayze R.D., El-Husseini A., Song C. Interleukin-1 beta modulates AMPA receptor expression and phosphorylation in hippocampal neurons. J. Neuroimmunol. 2006, 175:97-106.
    • (2006) J. Neuroimmunol. , vol.175 , pp. 97-106
    • Lai, A.Y.1    Swayze, R.D.2    El-Husseini, A.3    Song, C.4
  • 37
    • 34548656855 scopus 로고    scopus 로고
    • Signaling pathways downstream of pattern-recognition receptors and their cross talk
    • Lee M.S., Kim Y.J. Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annu. Rev. Biochem. 2007, 76:447-480.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 447-480
    • Lee, M.S.1    Kim, Y.J.2
  • 38
    • 46749136744 scopus 로고    scopus 로고
    • Discovery and development of Toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseases
    • Leon C.G., Tory R., Jia J., Sivak O., Wasan K.M. Discovery and development of Toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseases. Pharm. Res. 2008, 25:1751-1761.
    • (2008) Pharm. Res. , vol.25 , pp. 1751-1761
    • Leon, C.G.1    Tory, R.2    Jia, J.3    Sivak, O.4    Wasan, K.M.5
  • 39
    • 0034919056 scopus 로고    scopus 로고
    • Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines
    • Mantovani A., Locati M., Vecchi A., Sozzani S., Allavena P. Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines. Trends Immunol. 2001, 22:328-336.
    • (2001) Trends Immunol. , vol.22 , pp. 328-336
    • Mantovani, A.1    Locati, M.2    Vecchi, A.3    Sozzani, S.4    Allavena, P.5
  • 40
    • 79955053045 scopus 로고    scopus 로고
    • ICE/Caspase 1 inhibition reduces acute seizures and drug resistant chronic epileptic activity in mice
    • [Epub ahead of print].
    • Maroso, M., Balosso, S., Ravizza, T., Iori, V., Wright, C.I., French, J., Vezzani, A., 2011. ICE/Caspase 1 inhibition reduces acute seizures and drug resistant chronic epileptic activity in mice. Neurotherapeutics. [Epub ahead of print].
    • (2011) Neurotherapeutics
    • Maroso, M.1    Balosso, S.2    Ravizza, T.3    Iori, V.4    Wright, C.I.5    French, J.6    Vezzani, A.7
  • 42
    • 33746200051 scopus 로고    scopus 로고
    • Increased IL-1beta production from dsRNA-stimulated leukocytes in febrile seizures
    • Matsuo M., Sasaki K., Ichimaru T., Nakazato S., Hamasaki Y. Increased IL-1beta production from dsRNA-stimulated leukocytes in febrile seizures. Pediatr. Neurol. 2006, 35:102-106.
    • (2006) Pediatr. Neurol. , vol.35 , pp. 102-106
    • Matsuo, M.1    Sasaki, K.2    Ichimaru, T.3    Nakazato, S.4    Hamasaki, Y.5
  • 44
    • 0036518997 scopus 로고    scopus 로고
    • Innate immunity: the missing link in neuroprotection and neurodegeneration?
    • Nguyen M.D., Julien J.P., Rivest S. Innate immunity: the missing link in neuroprotection and neurodegeneration?. Nat. Rev. Neurosci. 2002, 3:216-227.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 216-227
    • Nguyen, M.D.1    Julien, J.P.2    Rivest, S.3
  • 45
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill L.A., Bowie A.G. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 2007, 7:353-364.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 46
    • 33750924816 scopus 로고    scopus 로고
    • The blood-brain barrier and epilepsy
    • Oby E., Janigro D. The blood-brain barrier and epilepsy. Epilepsia 2006, 47:1761-1774.
    • (2006) Epilepsia , vol.47 , pp. 1761-1774
    • Oby, E.1    Janigro, D.2
  • 50
    • 77953627102 scopus 로고    scopus 로고
    • Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling
    • Peltier D.C., Simms A., Farmer J.R., Miller D.J. Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling. J. Immunol. 2010, 184:7010-7021.
    • (2010) J. Immunol. , vol.184 , pp. 7010-7021
    • Peltier, D.C.1    Simms, A.2    Farmer, J.R.3    Miller, D.J.4
  • 51
    • 77954498319 scopus 로고    scopus 로고
    • Therapeutic approaches to epileptogenesis--hope on the horizon
    • Pitkanen A. Therapeutic approaches to epileptogenesis--hope on the horizon. Epilepsia 2010, 51(Suppl. 3):2-17.
    • (2010) Epilepsia , vol.51 , Issue.SUPPL. 3 , pp. 2-17
    • Pitkanen, A.1
  • 53
    • 36549071601 scopus 로고    scopus 로고
    • Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy
    • Ravizza T., Gagliardi B., Noe F., Boer K., Aronica E., Vezzani A. Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy. Neurobiol. Dis. 2008, 29:142-160.
    • (2008) Neurobiol. Dis. , vol.29 , pp. 142-160
    • Ravizza, T.1    Gagliardi, B.2    Noe, F.3    Boer, K.4    Aronica, E.5    Vezzani, A.6
  • 55
    • 29744460702 scopus 로고    scopus 로고
    • Status epilepticus induces time-dependent neuronal and astrocytic expression of interleukin-1 receptor type I in the rat limbic system
    • Ravizza T., Vezzani A. Status epilepticus induces time-dependent neuronal and astrocytic expression of interleukin-1 receptor type I in the rat limbic system. Neuroscience 2006, 137:301-308.
    • (2006) Neuroscience , vol.137 , pp. 301-308
    • Ravizza, T.1    Vezzani, A.2
  • 56
    • 77950516194 scopus 로고    scopus 로고
    • Contributions of peripheral inflammation to seizure susceptibility: cytokines and brain excitability
    • Riazi K., Galic M.A., Pittman Q.J. Contributions of peripheral inflammation to seizure susceptibility: cytokines and brain excitability. Epilepsy Res. 2010, 89:34-42.
    • (2010) Epilepsy Res. , vol.89 , pp. 34-42
    • Riazi, K.1    Galic, M.A.2    Pittman, Q.J.3
  • 57
    • 71549171171 scopus 로고    scopus 로고
    • The cortical innate immune response increases local neuronal excitability leading to seizures
    • Rodgers K.M., Hutchinson M.R., Northcutt A., Maier S.F., Watkins L.R., Barth D.S. The cortical innate immune response increases local neuronal excitability leading to seizures. Brain 2009, 132:2478-2486.
    • (2009) Brain , vol.132 , pp. 2478-2486
    • Rodgers, K.M.1    Hutchinson, M.R.2    Northcutt, A.3    Maier, S.F.4    Watkins, L.R.5    Barth, D.S.6
  • 58
    • 3042798891 scopus 로고    scopus 로고
    • The neurobiology of antiepileptic drugs
    • Rogawski M.A., Loscher W. The neurobiology of antiepileptic drugs. Nat. Rev. Neurosci. 2004, 5:553-564.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 553-564
    • Rogawski, M.A.1    Loscher, W.2
  • 59
    • 58149147514 scopus 로고    scopus 로고
    • Neural-activity-dependent release of S100B from astrocytes enhances kainate-induced gamma oscillations in vivo
    • Sakatani S., Seto-Ohshima A., Shinohara Y., Yamamoto Y., Yamamoto H., Itohara S., Hirase H. Neural-activity-dependent release of S100B from astrocytes enhances kainate-induced gamma oscillations in vivo. J. Neurosci. 2008, 28:10928-10936.
    • (2008) J. Neurosci. , vol.28 , pp. 10928-10936
    • Sakatani, S.1    Seto-Ohshima, A.2    Shinohara, Y.3    Yamamoto, Y.4    Yamamoto, H.5    Itohara, S.6    Hirase, H.7
  • 61
    • 43049154803 scopus 로고    scopus 로고
    • Effect of cytokines on neuronal excitability
    • Schafers M., Sorkin L. Effect of cytokines on neuronal excitability. Neurosci. Lett. 2008, 437:188-193.
    • (2008) Neurosci. Lett. , vol.437 , pp. 188-193
    • Schafers, M.1    Sorkin, L.2
  • 62
    • 0032194115 scopus 로고    scopus 로고
    • Generation of biologically active IL-1β by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1β processing
    • Schonbeck U., Mach F., Libby P. Generation of biologically active IL-1β by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1β processing. J. Immunol. 1998, 161:3340-3346.
    • (1998) J. Immunol. , vol.161 , pp. 3340-3346
    • Schonbeck, U.1    Mach, F.2    Libby, P.3
  • 63
    • 77954865635 scopus 로고    scopus 로고
    • Systemic inflammatory cells fight off neurodegenerative disease
    • Schwartz M., Shechter R. Systemic inflammatory cells fight off neurodegenerative disease. Nat. Rev. Neurol. 2010, 6:405-410.
    • (2010) Nat. Rev. Neurol. , vol.6 , pp. 405-410
    • Schwartz, M.1    Shechter, R.2
  • 64
    • 33644519960 scopus 로고    scopus 로고
    • Astrocyte dysfunction in neurological disorders: a molecular perspective
    • Seifert G., Schilling K., Steinhauser C. Astrocyte dysfunction in neurological disorders: a molecular perspective. Nat. Rev. Neurosci. 2006, 7:194-206.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 194-206
    • Seifert, G.1    Schilling, K.2    Steinhauser, C.3
  • 65
    • 77954862661 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury
    • Shlosberg D., Benifla M., Kaufer D., Friedman A. Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury. Nat. Rev. Neurol. 2010, 6:393-403.
    • (2010) Nat. Rev. Neurol. , vol.6 , pp. 393-403
    • Shlosberg, D.1    Benifla, M.2    Kaufer, D.3    Friedman, A.4
  • 66
    • 50249136097 scopus 로고    scopus 로고
    • Central nervous system infections and epilepsy
    • Singh G., Prabhakar S., Modi M. Central nervous system infections and epilepsy. Epilepsia 2008, 49(Suppl. 6):1.
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 6 , pp. 1
    • Singh, G.1    Prabhakar, S.2    Modi, M.3
  • 67
    • 68949122506 scopus 로고    scopus 로고
    • IL-1/IL-1ra balance in the brain revisited - evidence from transgenic mouse models
    • Spulber S., Bartfai T., Schultzberg M. IL-1/IL-1ra balance in the brain revisited - evidence from transgenic mouse models. Brain Behav. Immun. 2009, 23:573-579.
    • (2009) Brain Behav. Immun. , vol.23 , pp. 573-579
    • Spulber, S.1    Bartfai, T.2    Schultzberg, M.3
  • 68
    • 3242781549 scopus 로고    scopus 로고
    • Cell type-specific interleukin-1beta signaling in the CNS
    • Srinivasan D., Yen J.H., Joseph D.J., Friedman W. Cell type-specific interleukin-1beta signaling in the CNS. J. Neurosci. 2004, 24:6482-6488.
    • (2004) J. Neurosci. , vol.24 , pp. 6482-6488
    • Srinivasan, D.1    Yen, J.H.2    Joseph, D.J.3    Friedman, W.4
  • 69
    • 33747175900 scopus 로고    scopus 로고
    • Interleukin-1beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons
    • Tabarean I.V., Korn H., Bartfai T. Interleukin-1beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons. Neuroscience 2006, 141:1685-1695.
    • (2006) Neuroscience , vol.141 , pp. 1685-1695
    • Tabarean, I.V.1    Korn, H.2    Bartfai, T.3
  • 71
    • 4344627821 scopus 로고    scopus 로고
    • Endogenous ligands of Toll-like receptors
    • Tsan M.F., Gao B. Endogenous ligands of Toll-like receptors. J. Leukoc. Biol. 2004, 76:514-519.
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 514-519
    • Tsan, M.F.1    Gao, B.2
  • 72
    • 2942555126 scopus 로고    scopus 로고
    • Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy
    • Turrin N.P., Rivest S. Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy. Neurobiol. Dis. 2004, 16:321-334.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 321-334
    • Turrin, N.P.1    Rivest, S.2
  • 74
    • 38549138306 scopus 로고    scopus 로고
    • Sensing of viral infection and activation of innate immunity by Toll-like receptor 3
    • Vercammen E., Staal J., Beyaert R. Sensing of viral infection and activation of innate immunity by Toll-like receptor 3. Clin. Microbiol. Rev. 2008, 21:13-25.
    • (2008) Clin. Microbiol. Rev. , vol.21 , pp. 13-25
    • Vercammen, E.1    Staal, J.2    Beyaert, R.3
  • 75
  • 76
    • 46049103354 scopus 로고    scopus 로고
    • The role of cytokines in the pathophysiology of epilepsy
    • Vezzani A., Balosso S., Ravizza T. The role of cytokines in the pathophysiology of epilepsy. Brain Behav. Immun. 2008, 22:797-803.
    • (2008) Brain Behav. Immun. , vol.22 , pp. 797-803
    • Vezzani, A.1    Balosso, S.2    Ravizza, T.3
  • 77
    • 0033563321 scopus 로고    scopus 로고
    • Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures
    • Vezzani A., Conti M., De Luigi A., Ravizza T., Moneta D., Marchesi F., De Simoni M.G. Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures. J. Neurosci. 1999, 19:5054-5065.
    • (1999) J. Neurosci. , vol.19 , pp. 5054-5065
    • Vezzani, A.1    Conti, M.2    De Luigi, A.3    Ravizza, T.4    Moneta, D.5    Marchesi, F.6    De Simoni, M.G.7
  • 80
    • 0033993607 scopus 로고    scopus 로고
    • Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats
    • Virgili M., Contestabile A. Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats. Neurosci. Lett. 2000, 281:123-126.
    • (2000) Neurosci. Lett. , vol.281 , pp. 123-126
    • Virgili, M.1    Contestabile, A.2
  • 82
    • 34547279579 scopus 로고    scopus 로고
    • Cytokines and neuronal ion channels in health and disease
    • Viviani B., Gardoni F., Marinovich M. Cytokines and neuronal ion channels in health and disease. Int. Rev. Neurobiol. 2007, 82:247-263.
    • (2007) Int. Rev. Neurobiol. , vol.82 , pp. 247-263
    • Viviani, B.1    Gardoni, F.2    Marinovich, M.3
  • 83
    • 0033621660 scopus 로고    scopus 로고
    • Interleukin-1beta inhibits gamma-aminobutyric acid type A (GABA(A)) receptor current in cultured hippocampal neurons
    • Wang S., Cheng Q., Malik S., Yang J. Interleukin-1beta inhibits gamma-aminobutyric acid type A (GABA(A)) receptor current in cultured hippocampal neurons. J. Pharmacol. Exp. Ther. 2000, 292:497-504.
    • (2000) J. Pharmacol. Exp. Ther. , vol.292 , pp. 497-504
    • Wang, S.1    Cheng, Q.2    Malik, S.3    Yang, J.4
  • 84
    • 0027422183 scopus 로고
    • Interleukin-1 beta has excitatory effects on neurons of the bed nucleus of the stria terminalis
    • Wilkinson M.F., Mathieson W.B., Pittman Q.J. Interleukin-1 beta has excitatory effects on neurons of the bed nucleus of the stria terminalis. Brain Res. 1993, 625:342-346.
    • (1993) Brain Res. , vol.625 , pp. 342-346
    • Wilkinson, M.F.1    Mathieson, W.B.2    Pittman, Q.J.3
  • 85
    • 67349091742 scopus 로고    scopus 로고
    • Protective effect of resveratrol against kainate-induced temporal lobe epilepsy in rats
    • Wu Z., Xu Q., Zhang L., Kong D., Ma R., Wang L. Protective effect of resveratrol against kainate-induced temporal lobe epilepsy in rats. Neurochem. Res. 2009, 34:1393-1400.
    • (2009) Neurochem. Res. , vol.34 , pp. 1393-1400
    • Wu, Z.1    Xu, Q.2    Zhang, L.3    Kong, D.4    Ma, R.5    Wang, L.6
  • 86
    • 33745653534 scopus 로고    scopus 로고
    • Roles of IL-18 in basophils and mast cells
    • Yoshimoto T., Nakanishi K. Roles of IL-18 in basophils and mast cells. Allergol. Int. 2006, 55:105-113.
    • (2006) Allergol. Int. , vol.55 , pp. 105-113
    • Yoshimoto, T.1    Nakanishi, K.2
  • 87
    • 23844478190 scopus 로고    scopus 로고
    • Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex
    • Youn H.S., Lee J.Y., Fitzgerald K.A., Young H.A., Akira S., Hwang D.H. Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex. J. Immunol. 2005, 175:3339-3346.
    • (2005) J. Immunol. , vol.175 , pp. 3339-3346
    • Youn, H.S.1    Lee, J.Y.2    Fitzgerald, K.A.3    Young, H.A.4    Akira, S.5    Hwang, D.H.6
  • 88
    • 0030613694 scopus 로고    scopus 로고
    • Interleukin-1beta does not increase synaptic inhibition in hippocampal CA3 pyramidal and dentate gyrus granule cells of the rat in vitro
    • Zeise M.L., Espinoza J., Morales P., Nalli A. Interleukin-1beta does not increase synaptic inhibition in hippocampal CA3 pyramidal and dentate gyrus granule cells of the rat in vitro. Brain Res. 1997, 768:341-344.
    • (1997) Brain Res. , vol.768 , pp. 341-344
    • Zeise, M.L.1    Espinoza, J.2    Morales, P.3    Nalli, A.4
  • 89
    • 77952674793 scopus 로고    scopus 로고
    • Anti-inflammatory activities of resveratrol in the brain: role of resveratrol in microglial activation
    • Zhang F., Liu J., Shi J.S. Anti-inflammatory activities of resveratrol in the brain: role of resveratrol in microglial activation. Eur. J. Pharmacol. 2010, 636:1-7.
    • (2010) Eur. J. Pharmacol. , vol.636 , pp. 1-7
    • Zhang, F.1    Liu, J.2    Shi, J.S.3


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