Modification of Akt1 by methylglyoxal promotes the proliferation of vascular smooth muscle cells

FASEB Journal

Volumn 25, Issue 5, 2011, Pages 1746-1757

  Chang, Tuanjie ^a   Wang, Rui ^c   Olson, Douglas J H ^d   Mousseau, Darrell D ^b   Ross, Andrew R S ^e   Wu, Lingyun ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c LAKEHEAD UNIVERSITY   (Canada)

^d NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^e INSTITUTE OF OCEAN SCIENCES   (Canada)

Author keywords

Cell cycle; Cell signaling; Hypertension

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYSTEINE DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; METHYLGLYOXAL; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN P21; PROTEIN SERINE THREONINE KINASE; SERINE DERIVATIVE; SH 6; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL STRAIN HEK293; CONTROLLED STUDY; DNA SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE SILENCING; HUMAN; HUMAN CELL; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; HEK293 CELLS; HUMANS; MALE; MASS SPECTROMETRY; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PYRUVALDEHYDE; RATS;

EID: 79955666572     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-178053     Document Type: Article

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