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Volumn 276, Issue 5321, 1997, Pages 2042-2045

Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; GLUTAMATE RECEPTOR; PROTEIN KINASE;

EID: 0030744875     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.276.5321.2042     Document Type: Article
Times cited : (907)

References (50)
  • 1
    • 0027476024 scopus 로고
    • T. V. P. Bliss and G. L. Collingridge, Nature 361, 31 (1993); R. Malinow, Science 266, 1195 (1994); A. U. Larkman and J. J. B. Jack, Curr. Opin. Neurobiol. 5, 324 (1995).
    • (1993) Nature , vol.361 , pp. 31
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 2
    • 0027974244 scopus 로고
    • T. V. P. Bliss and G. L. Collingridge, Nature 361, 31 (1993); R. Malinow, Science 266, 1195 (1994); A. U. Larkman and J. J. B. Jack, Curr. Opin. Neurobiol. 5, 324 (1995).
    • (1994) Science , vol.266 , pp. 1195
    • Malinow, R.1
  • 3
    • 0029025641 scopus 로고
    • T. V. P. Bliss and G. L. Collingridge, Nature 361, 31 (1993); R. Malinow, Science 266, 1195 (1994); A. U. Larkman and J. J. B. Jack, Curr. Opin. Neurobiol. 5, 324 (1995).
    • (1995) Curr. Opin. Neurobiol. , vol.5 , pp. 324
    • Larkman, A.U.1    Jack, J.J.B.2
  • 10
    • 0028043656 scopus 로고
    • E. McGlade-McCulloh, H. Yamamoto, S. E. Tan, D. A. Brickey, T. R. Soderling, Nature 362, 640 (1993); M. Kolaj, R. Cerne, D. A. Brickey, M. Randic, J. Neurophysiol. 72, 2525 (1994); D. L. Pettit, S. Perlman, R. Malinow, Science 266, 1881 (1994).
    • (1994) J. Neurophysiol. , vol.72 , pp. 2525
    • Kolaj, M.1    Cerne, R.2    Brickey, D.A.3    Randic, M.4
  • 11
    • 0028579743 scopus 로고
    • E. McGlade-McCulloh, H. Yamamoto, S. E. Tan, D. A. Brickey, T. R. Soderling, Nature 362, 640 (1993); M. Kolaj, R. Cerne, D. A. Brickey, M. Randic, J. Neurophysiol. 72, 2525 (1994); D. L. Pettit, S. Perlman, R. Malinow, Science 266, 1881 (1994).
    • (1994) Science , vol.266 , pp. 1881
    • Pettit, D.L.1    Perlman, S.2    Malinow, R.3
  • 16
    • 0022519298 scopus 로고
    • S. G. Miller and M. B. Kennedy, Cell 44, 861 (1986); Y. L. Fong, W. L. Taylor, A. R. Means, T. R. Soderling, J. Biol. Chem. 264, 16759 (1989).
    • (1986) Cell , vol.44 , pp. 861
    • Miller, S.G.1    Kennedy, M.B.2
  • 21
    • 0027203084 scopus 로고    scopus 로고
    • U. Frey, Y. Y. Huang, E. R. Kandel, Science 260, 1661 (1993); G. Y. Hu et al., Nature 328, 426 (1987); E. Klann, S. J. Chen, J. D. Sweatt, Proc. Natl. Acad. Sci. U.S.A. 90, 8337 (1993); T. C. Sactor et al., ibid., p. 8342.
    • (1993) Science , vol.260 , pp. 1661
    • Frey, U.1    Huang, Y.Y.2    Kandel, E.R.3
  • 22
    • 0023280254 scopus 로고
    • U. Frey, Y. Y. Huang, E. R. Kandel, Science 260, 1661 (1993); G. Y. Hu et al., Nature 328, 426 (1987); E. Klann, S. J. Chen, J. D. Sweatt, Proc. Natl. Acad. Sci. U.S.A. 90, 8337 (1993); T. C. Sactor et al., ibid., p. 8342.
    • (1987) Nature , vol.328 , pp. 426
    • Hu, G.Y.1
  • 23
    • 0027170453 scopus 로고
    • U. Frey, Y. Y. Huang, E. R. Kandel, Science 260, 1661 (1993); G. Y. Hu et al., Nature 328, 426 (1987); E. Klann, S. J. Chen, J. D. Sweatt, Proc. Natl. Acad. Sci. U.S.A. 90, 8337 (1993); T. C. Sactor et al., ibid., p. 8342.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 8337
    • Klann, E.1    Chen, S.J.2    Sweatt, J.D.3
  • 24
    • 0027203084 scopus 로고    scopus 로고
    • U. Frey, Y. Y. Huang, E. R. Kandel, Science 260, 1661 (1993); G. Y. Hu et al., Nature 328, 426 (1987); E. Klann, S. J. Chen, J. D. Sweatt, Proc. Natl. Acad. Sci. U.S.A. 90, 8337 (1993); T. C. Sactor et al., ibid., p. 8342.
    • Proc. Natl. Acad. Sci. U.S.A. , pp. 8342
    • Sactor, T.C.1
  • 27
    • 0028274544 scopus 로고
    • P. Greengard, J. Jen, A. C. Nairn, C. F. Stevens, Science 253, 1135 (1991); C. Rosenmund et al., Nature 368, 853 (1994).
    • (1994) Nature , vol.368 , pp. 853
    • Rosenmund, C.1
  • 29
    • 0026780315 scopus 로고
    • H. Urushihara, M. Tohda, Y. Nomura, J. Biol. Chem. 267, 11697 (1992); L. Chen and L. Y. M. Huang, Nature 356, 521 (1992); L. Y. Wang, E. M. Dudek, M. D. Browning, J. F. McDonald, J. Physiol. (London) 475, 431 (1994); O. Hvalby et al., Proc. Natl. Acad. Sci. U.S.A. 91, 4761 (1994).
    • (1992) J. Biol. Chem. , vol.267 , pp. 11697
    • Urushihara, H.1    Tohda, M.2    Nomura, Y.3
  • 30
    • 0026552808 scopus 로고
    • H. Urushihara, M. Tohda, Y. Nomura, J. Biol. Chem. 267, 11697 (1992); L. Chen and L. Y. M. Huang, Nature 356, 521 (1992); L. Y. Wang, E. M. Dudek, M. D. Browning, J. F. McDonald, J. Physiol. (London) 475, 431 (1994); O. Hvalby et al., Proc. Natl. Acad. Sci. U.S.A. 91, 4761 (1994).
    • (1992) Nature , vol.356 , pp. 521
    • Chen, L.1    Huang, L.Y.M.2
  • 31
    • 0028204241 scopus 로고
    • H. Urushihara, M. Tohda, Y. Nomura, J. Biol. Chem. 267, 11697 (1992); L. Chen and L. Y. M. Huang, Nature 356, 521 (1992); L. Y. Wang, E. M. Dudek, M. D. Browning, J. F. McDonald, J. Physiol. (London) 475, 431 (1994); O. Hvalby et al., Proc. Natl. Acad. Sci. U.S.A. 91, 4761 (1994).
    • (1994) J. Physiol. (London) , vol.475 , pp. 431
    • Wang, L.Y.1    Dudek, E.M.2    Browning, M.D.3    McDonald, J.F.4
  • 32
    • 0028304816 scopus 로고
    • H. Urushihara, M. Tohda, Y. Nomura, J. Biol. Chem. 267, 11697 (1992); L. Chen and L. Y. M. Huang, Nature 356, 521 (1992); L. Y. Wang, E. M. Dudek, M. D. Browning, J. F. McDonald, J. Physiol. (London) 475, 431 (1994); O. Hvalby et al., Proc. Natl. Acad. Sci. U.S.A. 91, 4761 (1994).
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 4761
    • Hvalby, O.1
  • 34
    • 0001773989 scopus 로고    scopus 로고
    • D. T. Monaghan and R. J. Wenthold, Eds. Humana, Totowa, NJ
    • M. Hollmann, in The lonotropic Glutamate Receptors, D. T. Monaghan and R. J. Wenthold, Eds. (Humana, Totowa, NJ, 1997), pp. 39-80; T. R. Soderling, ibid., pp. 121-134.
    • (1997) The Lonotropic Glutamate Receptors , pp. 39-80
    • Hollmann, M.1
  • 39
    • 0026742451 scopus 로고
    • A. J. Silva, R. Paylor, J. M. Wehner, S. Tonegawa, Science 257, 206 (1992); A. J. Silva, C. F. Stevens, S. Tonegawa, Y. Wang, ibid., p. 201; M. Mayford, J. Wang, E. R. Kandel, T. J. O'Dell, Cell 81, 891 (1995); M. Mayford et al., Science 274, 1678 (1996).
    • (1992) Science , vol.257 , pp. 206
    • Silva, A.J.1    Paylor, R.2    Wehner, J.M.3    Tonegawa, S.4
  • 40
    • 0026637195 scopus 로고    scopus 로고
    • A. J. Silva, R. Paylor, J. M. Wehner, S. Tonegawa, Science 257, 206 (1992); A. J. Silva, C. F. Stevens, S. Tonegawa, Y. Wang, ibid., p. 201; M. Mayford, J. Wang, E. R. Kandel, T. J. O'Dell, Cell 81, 891 (1995); M. Mayford et al., Science 274, 1678 (1996).
    • Science , pp. 201
    • Silva, A.J.1    Stevens, C.F.2    Tonegawa, S.3    Wang, Y.4
  • 41
    • 0029066116 scopus 로고
    • A. J. Silva, R. Paylor, J. M. Wehner, S. Tonegawa, Science 257, 206 (1992); A. J. Silva, C. F. Stevens, S. Tonegawa, Y. Wang, ibid., p. 201; M. Mayford, J. Wang, E. R. Kandel, T. J. O'Dell, Cell 81, 891 (1995); M. Mayford et al., Science 274, 1678 (1996).
    • (1995) Cell , vol.81 , pp. 891
    • Mayford, M.1    Wang, J.2    Kandel, E.R.3    O'Dell, T.J.4
  • 42
    • 0029807527 scopus 로고    scopus 로고
    • A. J. Silva, R. Paylor, J. M. Wehner, S. Tonegawa, Science 257, 206 (1992); A. J. Silva, C. F. Stevens, S. Tonegawa, Y. Wang, ibid., p. 201; M. Mayford, J. Wang, E. R. Kandel, T. J. O'Dell, Cell 81, 891 (1995); M. Mayford et al., Science 274, 1678 (1996).
    • (1996) Science , vol.274 , pp. 1678
    • Mayford, M.1
  • 44
    • 0027395059 scopus 로고
    • T. Suzuki, K. Okumura-Noji, A. Ogura, Y. Kudo, R. Tanka, Proc. Natl. Acad. Sci. U.S.A. 89, 109 (1992); B. L. Patton, S. S. Malloy, M. B. Kennedy, Mol. Biol. Cell 4, 159 (1993).
    • (1993) Mol. Biol. Cell , vol.4 , pp. 159
    • Patton, B.L.1    Malloy, S.S.2    Kennedy, M.B.3
  • 46
    • 1842313147 scopus 로고    scopus 로고
    • note
    • P-Thr286, 1 μM microcystine was included in the blotting buffer to inhibit protein phosphatases in the Carnation milk.
  • 47
    • 1842361385 scopus 로고    scopus 로고
    • note
    • 32P-protein, incubated with GluR1 antibody (13) and protein A-Sepharose at 4°C for 5 hours, and centrifuged. CaM-KII was then immunoprecipitated from the supernatant (20). Immunoprecipitates were run on SDS-polyacrylamide gel electrophoresis (PAGE) and exposed on a Phosphor Screen (Molecular Dynamics) for analyses. The SDS-PAGE of the GluR1 immunoprecipitates were also subjected to protein immunoblot analyses to quantitate the amount of GluR1. Protein content of homogenates was determined by protein assay (Bio-Rad).
  • 48
    • 1842282575 scopus 로고    scopus 로고
    • note
    • 32P-AMPA-R was cut from the gel, subjected to two digestions with trypsin (16 and 4 hours with 75 μg of trypsin per milliliter), oxidized, and subjected to two-dimensional peptide mapping (cathode on the right) (20).
  • 49
    • 1842273780 scopus 로고    scopus 로고
    • note
    • 2, and 5 mM Hepes. When added to intracellular solution, activated CaM-KII [truncated at residue 316 and autothiophosphorylated (8)] was at 0.4 μM. Glutamate (10 mM) was delivered to single cells by rapid application (9). Currents were filtered at 2 kHz and digitized at 10 kHz.
  • 50
    • 1842396173 scopus 로고    scopus 로고
    • 286 antibody
    • 286 antibody.


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