An enhanced tiered toxicity testing framework with triggers for assessing hazards and risks of commodity chemicals

Regulatory Toxicology and Pharmacology

Volumn 58, Issue 3, 2010, Pages 382-394

  Plunkett, Laura M ^a   Kaplan, A Michael ^b   Becker, Richard A ^c  

^a Integrative Biostrategies   (United States)

^b DUPONT COMPANY   (United States)

^c American Chemistry Council   (United States)

Author keywords

Animal welfare; Biologically based decision triggers; Integrated testing strategies; REACH; Tiered toxicity testing; TSCA

Indexed keywords

CHEMICAL AGENT; COMMODITY CHEMICAL; CONSUMER PRODUCT; INDUSTRIAL CHEMICAL; UNCLASSIFIED DRUG; INORGANIC COMPOUND; ORGANIC COMPOUND;

ACUTE TOXICITY; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL SAFETY; CHILD; DECISION MAKING; DEVELOPMENTAL TOXICITY; EUROPE; GENOTOXICITY; HEALTH HAZARD; HUMAN; IMMUNOTOXICITY; INFANT; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PRODUCT SAFETY; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; TARGET ORGAN; TOXICITY TESTING; UNITED STATES; ANIMAL; DOSE RESPONSE; DRUG SURVEILLANCE PROGRAM; METHODOLOGY; PRACTICE GUIDELINE; STANDARD;

ANIMALIA;

ANIMALS; CHILD; CONSUMER PRODUCT SAFETY; DOSE-RESPONSE RELATIONSHIP, DRUG; EUROPE; GUIDELINES AS TOPIC; HUMANS; INFANT; INORGANIC CHEMICALS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGANIC CHEMICALS; RISK ASSESSMENT; TOXICITY TESTS; UNITED STATES;

EID: 79955619421     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2010.08.003     Document Type: Article

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