Integrated decision-tree testing strategies for developmental and reproductive toxicity with respect to the requirements of the EU REACH legislation

Alternatives to Laboratory Animals

Volumn 36, Issue SUPPL. 1, 2008, Pages 123-138

  Grindon, Christina ^a   Combes, Robert ^a   Cronin, Mark T D ^b   Roberts, David W ^b   Garrod, John F ^c  

^a RUSSELL AND BURCH HOUSE   (United Kingdom)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^c DEFRA   (United Kingdom)

Author keywords

Animal testing; Decision trees; Defra; Developmental toxicity; In silico models; In vitro testing; Integrated testing strategies; REACH; Reproductive toxicity; Risk assessment; Three rs

Indexed keywords

ANIMAL TESTING ALTERNATIVE; CELL PROLIFERATION; COMPUTER MODEL; CYTOTOXICITY; EMBRYOTOXICITY; HUMAN; IN VITRO STUDY; MEDICAL RESEARCH; NONHUMAN; NOTE; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; TERATOGENESIS; TOXICITY TESTING;

ANIMALIA;

EID: 57349096415     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290803601s10     Document Type: Note

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