The multiple-specificity landscape of modular peptide recognition domains

Molecular Systems Biology

Volumn 7, Issue , 2011, Pages

  Gfeller, David ^a,e   Butty, Frank ^a   Wierzbicka, Marta ^a   Verschueren, Erik ^b   Vanhee, Peter ^b   Huang, Haiming ^a   Ernst, Andreas ^a   Dar, Nisa ^a   Stagljar, Igor ^a   Serrano, Luis ^b   Sidhu, Sachdev S ^a   Bader, Gary D ^a,c,d   Kim, Philip M ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^c UNIVERSITY OF TORONTO   (Canada)

^d MOUNT SINAI HOSPITAL   (Canada)

^e SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

binding specificity; PDZ; peptide recognition domains; phage display; residue correlations

Indexed keywords

DROSOPHILA PROTEIN; PDZ PROTEIN; PDZ1 PROTEIN; PEPTIDE; PROTEIN DLG1; PROTEIN KINASE; PROTEIN SH3; PROTEIN WW; UNCLASSIFIED DRUG; DLG1 PROTEIN, HUMAN; MEMBRANE PROTEIN; SCRIB PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; MOLECULAR RECOGNITION; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; YEAST; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CLUSTER ANALYSIS; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; PDZ DOMAIN; PROTEIN ANALYSIS; SRC HOMOLOGY DOMAIN; SYSTEMS BIOLOGY;

EUKARYOTA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CLUSTER ANALYSIS; HUMANS; MEMBRANE PROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PDZ DOMAINS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; SYSTEMS BIOLOGY; TUMOR SUPPRESSOR PROTEINS;

EID: 79955569676     PISSN: 17444292     EISSN: 17444292     Source Type: Journal    
DOI: 10.1038/msb.2011.18     Document Type: Article

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