-
1
-
-
0038556703
-
Gene-targeting reveals physiological roles and complex regulation of the phosphoinositide 3-kinases
-
Foukas L.C., and Okkenhaug K. Gene-targeting reveals physiological roles and complex regulation of the phosphoinositide 3-kinases. Arch. Biochem. Biophys. 414 1 (2003 Jun 1) 13-18
-
(2003)
Arch. Biochem. Biophys.
, vol.414
, Issue.1
, pp. 13-18
-
-
Foukas, L.C.1
Okkenhaug, K.2
-
2
-
-
34247391898
-
Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo
-
Calleja V., Alcor D., Laguerre M., Park J., Vojnovic B., Hemmings B.A., et al. Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo. PLoS Biol. 5 4 (2007 Apr) e95
-
(2007)
PLoS Biol.
, vol.5
, Issue.4
-
-
Calleja, V.1
Alcor, D.2
Laguerre, M.3
Park, J.4
Vojnovic, B.5
Hemmings, B.A.6
-
3
-
-
36749002266
-
Protein kinases, from B to C
-
Cameron A.J., De Rycker M., Calleja V., Alcor D., Kjaer S., Kostelecky B., et al. Protein kinases, from B to C. Biochem. Soc. Trans. 35 Pt 5 (2007 Nov) 1013-1017
-
(2007)
Biochem. Soc. Trans.
, vol.35
, Issue.PART 5
, pp. 1013-1017
-
-
Cameron, A.J.1
De Rycker, M.2
Calleja, V.3
Alcor, D.4
Kjaer, S.5
Kostelecky, B.6
-
4
-
-
0242468741
-
Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change
-
Milburn C.C., Deak M., Kelly S.M., Price N.C., Alessi D.R., and Van Aalten D.M. Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change. Biochem. J. 375 Pt 3 (2003 Nov 1) 531-538
-
(2003)
Biochem. J.
, vol.375
, Issue.PART 3
, pp. 531-538
-
-
Milburn, C.C.1
Deak, M.2
Kelly, S.M.3
Price, N.C.4
Alessi, D.R.5
Van Aalten, D.M.6
-
5
-
-
33751348056
-
Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKC[alpha], but Not S6K1
-
Guertin D.A., Stevens D.M., Thoreen C.C., Burds A.A., Kalaany N.Y., Moffat J., et al. Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKC[alpha], but Not S6K1. Dev. Cell 11 6 (2006) 859-871
-
(2006)
Dev. Cell
, vol.11
, Issue.6
, pp. 859-871
-
-
Guertin, D.A.1
Stevens, D.M.2
Thoreen, C.C.3
Burds, A.A.4
Kalaany, N.Y.5
Moffat, J.6
-
6
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov D.D., Guertin D.A., Ali S.M., and Sabatini D.M. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307 5712 (2005 Feb 18) 1098-1101
-
(2005)
Science
, vol.307
, Issue.5712
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
7
-
-
2942726155
-
The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation
-
Van Der Heide L.P., Hoekman M.F., and Smidt M.P. The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation. Biochem. J. 380 Pt 2 (2004 Jun 1) 297-309
-
(2004)
Biochem. J.
, vol.380
, Issue.PART 2
, pp. 297-309
-
-
Van Der Heide, L.P.1
Hoekman, M.F.2
Smidt, M.P.3
-
8
-
-
1842830427
-
Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes
-
Shiraishi I., Melendez J., Ahn Y., Skavdahl M., Murphy E., Welch S., et al. Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circ. Res. 94 7 (2004 Apr 16) 884-891
-
(2004)
Circ. Res.
, vol.94
, Issue.7
, pp. 884-891
-
-
Shiraishi, I.1
Melendez, J.2
Ahn, Y.3
Skavdahl, M.4
Murphy, E.5
Welch, S.6
-
9
-
-
0035947744
-
Myocardial Akt activation and gender: increased nuclear activity in females versus males
-
Camper-Kirby D., Welch S., Walker A., Shiraishi I., Setchell K.D., Schaefer E., et al. Myocardial Akt activation and gender: increased nuclear activity in females versus males. Circ. Res. 88 10 (2001 May 25) 1020-1027
-
(2001)
Circ. Res.
, vol.88
, Issue.10
, pp. 1020-1027
-
-
Camper-Kirby, D.1
Welch, S.2
Walker, A.3
Shiraishi, I.4
Setchell, K.D.5
Schaefer, E.6
-
10
-
-
0034651983
-
Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart
-
Fujio Y., Nguyen T., Wencker D., Kitsis R.N., and Walsh K. Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. Circulation 101 6 (2000 Feb 15) 660-667
-
(2000)
Circulation
, vol.101
, Issue.6
, pp. 660-667
-
-
Fujio, Y.1
Nguyen, T.2
Wencker, D.3
Kitsis, R.N.4
Walsh, K.5
-
11
-
-
0034517548
-
Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size following ischemia-reperfusion injury in vivo
-
Miao W., Luo Z., Kitsis R.N., and Walsh K. Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size following ischemia-reperfusion injury in vivo. J. Mol. Cell. Cardiol. 32 12 (2000 Dec) 2397-2402
-
(2000)
J. Mol. Cell. Cardiol.
, vol.32
, Issue.12
, pp. 2397-2402
-
-
Miao, W.1
Luo, Z.2
Kitsis, R.N.3
Walsh, K.4
-
12
-
-
0033534088
-
Adenoviral gene transfer of activated phosphatidylinositol 3′-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro
-
Matsui T., Li L., del Monte F., Fukui Y., Franke T.F., Hajjar R.J., et al. Adenoviral gene transfer of activated phosphatidylinositol 3′-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro. Circulation 100 23 (1999 Dec 7) 2373-2379
-
(1999)
Circulation
, vol.100
, Issue.23
, pp. 2373-2379
-
-
Matsui, T.1
Li, L.2
del Monte, F.3
Fukui, Y.4
Franke, T.F.5
Hajjar, R.J.6
-
13
-
-
0035970041
-
Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction
-
Negoro S., Oh H., Tone E., Kunisada K., Fujio Y., Walsh K., et al. Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction. Circulation 103 4 (2001 Jan 30) 555-561
-
(2001)
Circulation
, vol.103
, Issue.4
, pp. 555-561
-
-
Negoro, S.1
Oh, H.2
Tone, E.3
Kunisada, K.4
Fujio, Y.5
Walsh, K.6
-
14
-
-
33747035594
-
Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy
-
Tsujita Y., Muraski J., Shiraishi I., Kato T., Kajstura J., Anversa P., et al. Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy. Proc. Natl. Acad. Sci. U. S. A. (2006 Aug 1)
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
-
-
Tsujita, Y.1
Muraski, J.2
Shiraishi, I.3
Kato, T.4
Kajstura, J.5
Anversa, P.6
-
15
-
-
33747384625
-
Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population
-
Gude N., Muraski J., Rubio M., Kajstura J., Schaefer E., Anversa P., et al. Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population. Circ. Res. 99 4 (2006 Aug 18) 381-388
-
(2006)
Circ. Res.
, vol.99
, Issue.4
, pp. 381-388
-
-
Gude, N.1
Muraski, J.2
Rubio, M.3
Kajstura, J.4
Schaefer, E.5
Anversa, P.6
-
16
-
-
0036200937
-
Akt/protein kinase B promotes organ growth in transgenic mice
-
Shioi T., McMullen J.R., Kang P.M., Douglas P.S., Obata T., Franke T.F., et al. Akt/protein kinase B promotes organ growth in transgenic mice. Mol. Cell. Biol. 22 8 (2002 Apr) 2799-2809
-
(2002)
Mol. Cell. Biol.
, vol.22
, Issue.8
, pp. 2799-2809
-
-
Shioi, T.1
McMullen, J.R.2
Kang, P.M.3
Douglas, P.S.4
Obata, T.5
Franke, T.F.6
-
17
-
-
0037151104
-
Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart
-
Matsui T., Li L., Wu J.C., Cook S.A., Nagoshi T., Picard M.H., et al. Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart. J. Biol. Chem. 277 25 (2002 Jun 21) 22896-22901
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.25
, pp. 22896-22901
-
-
Matsui, T.1
Li, L.2
Wu, J.C.3
Cook, S.A.4
Nagoshi, T.5
Picard, M.H.6
-
18
-
-
0033595011
-
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
-
Biggs III W.H., Meisenhelder J., Hunter T., Cavenee W.K., and Arden K.C. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc. Natl. Acad. Sci. U. S. A. 96 13 (1999 Jun 22) 7421-7426
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, Issue.13
, pp. 7421-7426
-
-
Biggs III, W.H.1
Meisenhelder, J.2
Hunter, T.3
Cavenee, W.K.4
Arden, K.C.5
-
19
-
-
0033560896
-
Direct control of the Forkhead transcription factor AFX by protein kinase B
-
Kops G.J., de Ruiter N.D., De Vries-Smits A.M., Powell D.R., Bos J.L., and Burgering B.M. Direct control of the Forkhead transcription factor AFX by protein kinase B. Nature 398 6728 (1999 Apr 15) 630-634
-
(1999)
Nature
, vol.398
, Issue.6728
, pp. 630-634
-
-
Kops, G.J.1
de Ruiter, N.D.2
De Vries-Smits, A.M.3
Powell, D.R.4
Bos, J.L.5
Burgering, B.M.6
-
20
-
-
0032484019
-
CREB is a regulatory target for the protein kinase Akt/PKB
-
Du K., and Montminy M. CREB is a regulatory target for the protein kinase Akt/PKB. J. Biol. Chem. 273 49 (1998 Dec 4) 32377-32379
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.49
, pp. 32377-32379
-
-
Du, K.1
Montminy, M.2
-
21
-
-
33644699984
-
Nuclear targeting of Akt enhances ventricular function and myocyte contractility
-
Rota M., Boni A., Urbanek K., Padin-Iruegas M.E., Kajstura T.J., Fiore G., et al. Nuclear targeting of Akt enhances ventricular function and myocyte contractility. Circ. Res. 97 12 (2005 Dec 9) 1332-1341
-
(2005)
Circ. Res.
, vol.97
, Issue.12
, pp. 1332-1341
-
-
Rota, M.1
Boni, A.2
Urbanek, K.3
Padin-Iruegas, M.E.4
Kajstura, T.J.5
Fiore, G.6
-
22
-
-
26444507242
-
Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt
-
Kato T., Muraski J., Chen Y., Tsujita Y., Wall J., Glembotski C.C., et al. Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt. J. Clin. Invest. 115 10 (2005 Oct) 2716-2730
-
(2005)
J. Clin. Invest.
, vol.115
, Issue.10
, pp. 2716-2730
-
-
Kato, T.1
Muraski, J.2
Chen, Y.3
Tsujita, Y.4
Wall, J.5
Glembotski, C.C.6
-
23
-
-
0034282751
-
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
-
Gillooly D.J., Morrow I.C., Lindsay M., Gould R., Bryant N.J., Gaullier J.M., et al. Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J. 19 17 (2000 Sep 1) 4577-4588
-
(2000)
EMBO J.
, vol.19
, Issue.17
, pp. 4577-4588
-
-
Gillooly, D.J.1
Morrow, I.C.2
Lindsay, M.3
Gould, R.4
Bryant, N.J.5
Gaullier, J.M.6
-
24
-
-
0037880798
-
Nuclear lipid signalling
-
Irvine R.F. Nuclear lipid signalling. Nat. Rev. Mol. Cell. Biol. 4 5 (2003 May) 349-360
-
(2003)
Nat. Rev. Mol. Cell. Biol.
, vol.4
, Issue.5
, pp. 349-360
-
-
Irvine, R.F.1
-
25
-
-
0037441468
-
Nuclear lipids: new functions for old molecules?
-
Martelli A.M., Tabellini G., Borgatti P., Bortul R., Capitani S., and Neri L.M. Nuclear lipids: new functions for old molecules?. J. Cell. Biochem. 88 3 (2003 Feb 15) 455-461
-
(2003)
J. Cell. Biochem.
, vol.88
, Issue.3
, pp. 455-461
-
-
Martelli, A.M.1
Tabellini, G.2
Borgatti, P.3
Bortul, R.4
Capitani, S.5
Neri, L.M.6
-
26
-
-
0345193700
-
Nuclear translocation of phosphatidylinositol 3-kinase in rat pheochromocytoma PC 12 cells after treatment with nerve growth factor
-
Neri L.M., Milani D., Bertolaso L., Stroscio M., Bertagnolo V., and Capitani S. Nuclear translocation of phosphatidylinositol 3-kinase in rat pheochromocytoma PC 12 cells after treatment with nerve growth factor. Cell. Mol. Biol. (Noisy-le-grand) 40 5 (1994 Jul) 619-626
-
(1994)
Cell. Mol. Biol. (Noisy-le-grand)
, vol.40
, Issue.5
, pp. 619-626
-
-
Neri, L.M.1
Milani, D.2
Bertolaso, L.3
Stroscio, M.4
Bertagnolo, V.5
Capitani, S.6
-
27
-
-
0344270855
-
Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function
-
Lim M.A., Kikani C.K., Wick M.J., and Dong L.Q. Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function. Proc. Natl. Acad. Sci. U. S. A. 100 24 (2003 Nov 25) 14006-14011
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, Issue.24
, pp. 14006-14011
-
-
Lim, M.A.1
Kikani, C.K.2
Wick, M.J.3
Dong, L.Q.4
-
28
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic M., Alessi D.R., Meier R., Fernandez A., Lamb N.J., Frech M., et al. Role of translocation in the activation and function of protein kinase B. J. Biol. Chem. 272 50 (1997 Dec 12) 31515-31524
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.50
, pp. 31515-31524
-
-
Andjelkovic, M.1
Alessi, D.R.2
Meier, R.3
Fernandez, A.4
Lamb, N.J.5
Frech, M.6
-
29
-
-
0031715393
-
Insulin rapidly induces nuclear translocation of PI3-kinase in HepG2 cells
-
Kim S.J. Insulin rapidly induces nuclear translocation of PI3-kinase in HepG2 cells. Biochem. Mol. Biol. Int. 46 1 (1998 Sep) 187-196
-
(1998)
Biochem. Mol. Biol. Int.
, vol.46
, Issue.1
, pp. 187-196
-
-
Kim, S.J.1
-
30
-
-
0033844188
-
Phosphatidylinositol 3-kinase translocates to the nucleus of osteoblast-like MC3T3-E1 cells in response to insulin-like growth factor I and platelet-derived growth factor but not to the proapoptotic cytokine tumor necrosis factor alpha
-
Martelli A.M., Borgatti P., Bortul R., Manfredini M., Massari L., Capitani S., et al. Phosphatidylinositol 3-kinase translocates to the nucleus of osteoblast-like MC3T3-E1 cells in response to insulin-like growth factor I and platelet-derived growth factor but not to the proapoptotic cytokine tumor necrosis factor alpha. J. Bone Miner. Res. 15 9 (2000 Sep) 1716-1730
-
(2000)
J. Bone Miner. Res.
, vol.15
, Issue.9
, pp. 1716-1730
-
-
Martelli, A.M.1
Borgatti, P.2
Bortul, R.3
Manfredini, M.4
Massari, L.5
Capitani, S.6
-
31
-
-
0029858116
-
Cytoplasmic and nuclear localization sites of phosphatidylinositol 3-kinase in human osteosarcoma sensitive and multidrug-resistant Saos-2 cells
-
Zini N., Ognibene A., Bavelloni A., Santi S., Sabatelli P., Baldini N., et al. Cytoplasmic and nuclear localization sites of phosphatidylinositol 3-kinase in human osteosarcoma sensitive and multidrug-resistant Saos-2 cells. Histochem. Cell Biol. 106 5 (1996 Nov) 457-464
-
(1996)
Histochem. Cell Biol.
, vol.106
, Issue.5
, pp. 457-464
-
-
Zini, N.1
Ognibene, A.2
Bavelloni, A.3
Santi, S.4
Sabatelli, P.5
Baldini, N.6
-
32
-
-
0033561655
-
Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis
-
Sano T., Lin H., Chen X., Langford L.A., Koul D., Bondy M.L., et al. Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis. Cancer Res. 59 8 (1999 Apr 15) 1820-1824
-
(1999)
Cancer Res.
, vol.59
, Issue.8
, pp. 1820-1824
-
-
Sano, T.1
Lin, H.2
Chen, X.3
Langford, L.A.4
Koul, D.5
Bondy, M.L.6
-
33
-
-
3242698804
-
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease
-
Oudit G.Y., Sun H., Kerfant B.G., Crackower M.A., Penninger J.M., and Backx P.H. The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease. J. Mol. Cell. Cardiol. 37 2 (2004 Aug) 449-471
-
(2004)
J. Mol. Cell. Cardiol.
, vol.37
, Issue.2
, pp. 449-471
-
-
Oudit, G.Y.1
Sun, H.2
Kerfant, B.G.3
Crackower, M.A.4
Penninger, J.M.5
Backx, P.H.6
-
34
-
-
0034213075
-
The conserved phosphoinositide 3-kinase pathway determines heart size in mice
-
Shioi T., Kang P.M., Douglas P.S., Hampe J., Yballe C.M., Lawitts J., et al. The conserved phosphoinositide 3-kinase pathway determines heart size in mice. EMBO J. 19 11 (2000 Jun 1) 2537-2548
-
(2000)
EMBO J.
, vol.19
, Issue.11
, pp. 2537-2548
-
-
Shioi, T.1
Kang, P.M.2
Douglas, P.S.3
Hampe, J.4
Yballe, C.M.5
Lawitts, J.6
-
35
-
-
18644372367
-
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
-
Crackower M.A., Oudit G.Y., Kozieradzki I., Sarao R., Sun H., Sasaki T., et al. Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell 110 6 (2002 Sep 20) 737-749
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 737-749
-
-
Crackower, M.A.1
Oudit, G.Y.2
Kozieradzki, I.3
Sarao, R.4
Sun, H.5
Sasaki, T.6
-
36
-
-
0141737071
-
Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia
-
Mora A., Davies A.M., Bertrand L., Sharif I., Budas G.R., Jovanovic S., et al. Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia. EMBO J. 22 18 (2003 Sep 15) 4666-4676
-
(2003)
EMBO J.
, vol.22
, Issue.18
, pp. 4666-4676
-
-
Mora, A.1
Davies, A.M.2
Bertrand, L.3
Sharif, I.4
Budas, G.R.5
Jovanovic, S.6
-
37
-
-
0037383322
-
GSK-3: tricks of the trade for a multi-tasking kinase
-
Doble B.W., and Woodgett J.R. GSK-3: tricks of the trade for a multi-tasking kinase. J. Cell Sci. 116 Pt 7 (2003 Apr 1) 1175-1186
-
(2003)
J. Cell Sci.
, vol.116
, Issue.PART 7
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
38
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle T., and Hall M.N. TOR, a central controller of cell growth. Cell 103 2 (2000 Oct 13) 253-262
-
(2000)
Cell
, vol.103
, Issue.2
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
39
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
Dimmeler S., Fleming I., Fisslthaler B., Hermann C., Busse R., and Zeiher A.M. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399 6736 (1999 Jun 10) 601-605
-
(1999)
Nature
, vol.399
, Issue.6736
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
40
-
-
0033542414
-
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
-
Fulton D., Gratton J.P., McCabe T.J., Fontana J., Fujio Y., Walsh K., et al. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 399 6736 (1999 Jun 10) 597-601
-
(1999)
Nature
, vol.399
, Issue.6736
, pp. 597-601
-
-
Fulton, D.1
Gratton, J.P.2
McCabe, T.J.3
Fontana, J.4
Fujio, Y.5
Walsh, K.6
-
41
-
-
0036751393
-
Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways
-
Hue L., Beauloye C., Marsin A.S., Bertrand L., Horman S., and Rider M.H. Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways. J. Mol. Cell. Cardiol. 34 9 (2002 Sep) 1091-1097
-
(2002)
J. Mol. Cell. Cardiol.
, vol.34
, Issue.9
, pp. 1091-1097
-
-
Hue, L.1
Beauloye, C.2
Marsin, A.S.3
Bertrand, L.4
Horman, S.5
Rider, M.H.6
-
42
-
-
0037163050
-
Regulation of Raf-Akt Cross-talk
-
Moelling K., Schad K., Bosse M., Zimmermann S., and Schweneker M. Regulation of Raf-Akt Cross-talk. J. Biol. Chem. 277 34 (2002 Aug 23) 31099-31106
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.34
, pp. 31099-31106
-
-
Moelling, K.1
Schad, K.2
Bosse, M.3
Zimmermann, S.4
Schweneker, M.5
-
43
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley L.C. The phosphoinositide 3-kinase pathway. Science 296 5573 (2002 May 31) 1655-1657
-
(2002)
Science
, vol.296
, Issue.5573
, pp. 1655-1657
-
-
Cantley, L.C.1
-
44
-
-
0032752063
-
Cellular survival: a play in three Akts
-
Datta S.R., Brunet A., and Greenberg M.E. Cellular survival: a play in three Akts. Genes Dev. 13 22 (1999 Nov 15) 2905-2927
-
(1999)
Genes Dev.
, vol.13
, Issue.22
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
45
-
-
0035369623
-
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
-
Brunet A., Datta S.R., and Greenberg M.E. Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr. Opin. Neurobiol. 11 3 (2001 Jun) 297-305
-
(2001)
Curr. Opin. Neurobiol.
, vol.11
, Issue.3
, pp. 297-305
-
-
Brunet, A.1
Datta, S.R.2
Greenberg, M.E.3
-
46
-
-
0030727172
-
Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta
-
Meier R., Alessi D.R., Cron P., Andjelkovic M., and Hemmings B.A. Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta. J. Biol. Chem. 272 48 (1997 Nov 28) 30491-30497
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.48
, pp. 30491-30497
-
-
Meier, R.1
Alessi, D.R.2
Cron, P.3
Andjelkovic, M.4
Hemmings, B.A.5
-
47
-
-
0346434149
-
Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation
-
Bijur G.N., and Jope R.S. Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation. J. Neurochem. 87 6 (2003 Dec) 1427-1435
-
(2003)
J. Neurochem.
, vol.87
, Issue.6
, pp. 1427-1435
-
-
Bijur, G.N.1
Jope, R.S.2
-
48
-
-
0034610449
-
Insulin prevents cardiomyocytes from oxidative stress-induced apoptosis through activation of PI3 kinase/Akt
-
Aikawa R., Nawano M., Gu Y., Katagiri H., Asano T., Zhu W., et al. Insulin prevents cardiomyocytes from oxidative stress-induced apoptosis through activation of PI3 kinase/Akt. Circulation 102 23 (2000 Dec 5) 2873-2879
-
(2000)
Circulation
, vol.102
, Issue.23
, pp. 2873-2879
-
-
Aikawa, R.1
Nawano, M.2
Gu, Y.3
Katagiri, H.4
Asano, T.5
Zhu, W.6
-
49
-
-
0034704134
-
Expression of constitutively active phosphatidylinositol 3-kinase inhibits activation of caspase 3 and apoptosis of cardiac muscle cells
-
Wu W., Lee W.L., Wu Y.Y., Chen D., Liu T.J., Jang A., et al. Expression of constitutively active phosphatidylinositol 3-kinase inhibits activation of caspase 3 and apoptosis of cardiac muscle cells. J. Biol. Chem. 275 51 (2000 Dec 22) 40113-40119
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.51
, pp. 40113-40119
-
-
Wu, W.1
Lee, W.L.2
Wu, Y.Y.3
Chen, D.4
Liu, T.J.5
Jang, A.6
-
50
-
-
0037164747
-
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT
-
Baldanzi G., Filigheddu N., Cutrupi S., Catapano F., Bonissoni S., Fubini A., et al. Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT. J. Cell. Biol. 159 6 (2002 Dec 23) 1029-1037
-
(2002)
J. Cell. Biol.
, vol.159
, Issue.6
, pp. 1029-1037
-
-
Baldanzi, G.1
Filigheddu, N.2
Cutrupi, S.3
Catapano, F.4
Bonissoni, S.5
Fubini, A.6
-
51
-
-
0035448879
-
Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene
-
Chen W.S., Xu P.Z., Gottlob K., Chen M.L., Sokol K., Shiyanova T., et al. Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. Genes Dev. 15 17 (2001 Sep 1) 2203-2208
-
(2001)
Genes Dev.
, vol.15
, Issue.17
, pp. 2203-2208
-
-
Chen, W.S.1
Xu, P.Z.2
Gottlob, K.3
Chen, M.L.4
Sokol, K.5
Shiyanova, T.6
-
52
-
-
0035914388
-
Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
-
Cho H., Thorvaldsen J.L., Chu Q., Feng F., and Birnbaum M.J. Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J. Biol. Chem.. 276 42 (2001 Oct 19) 38349-38352
-
(2001)
J. Biol. Chem..
, vol.276
, Issue.42
, pp. 38349-38352
-
-
Cho, H.1
Thorvaldsen, J.L.2
Chu, Q.3
Feng, F.4
Birnbaum, M.J.5
-
53
-
-
0037125980
-
Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice
-
Condorelli G., Drusco A., Stassi G., Bellacosa A., Roncarati R., Iaccarino G., et al. Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 99 19 (2002 Sep 17) 12333-12338
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, Issue.19
, pp. 12333-12338
-
-
Condorelli, G.1
Drusco, A.2
Stassi, G.3
Bellacosa, A.4
Roncarati, R.5
Iaccarino, G.6
-
54
-
-
0037057801
-
The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system
-
Neri L.M., Borgatti P., Capitani S., and Martelli A.M. The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system. Biochim. Biophys. Acta 1584 2-3 (2002 Oct 10) 73-80
-
(2002)
Biochim. Biophys. Acta
, vol.1584
, Issue.2-3
, pp. 73-80
-
-
Neri, L.M.1
Borgatti, P.2
Capitani, S.3
Martelli, A.M.4
-
55
-
-
27844535741
-
Class reunion: PTEN joins the nuclear crew
-
Lian Z., and Di Cristofano A. Class reunion: PTEN joins the nuclear crew. Oncogene 24 50 (2005 Nov 14) 7394-7400
-
(2005)
Oncogene
, vol.24
, Issue.50
, pp. 7394-7400
-
-
Lian, Z.1
Di Cristofano, A.2
-
56
-
-
0242266953
-
RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development
-
Adini I., Rabinovitz I., Sun J.F., Prendergast G.C., and Benjamin L.E. RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development. Genes Dev. 17 21 (2003 Nov 1) 2721-2732
-
(2003)
Genes Dev.
, vol.17
, Issue.21
, pp. 2721-2732
-
-
Adini, I.1
Rabinovitz, I.2
Sun, J.F.3
Prendergast, G.C.4
Benjamin, L.E.5
-
57
-
-
19344372551
-
Akt1 contains a functional leucine-rich nuclear export sequence
-
Saji M., Vasko V., Kada F., Allbritton E.H., Burman K.D., and Ringel M.D. Akt1 contains a functional leucine-rich nuclear export sequence. Biochem. Biophys. Res. Commun. 332 1 (2005 Jun 24) 167-173
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.332
, Issue.1
, pp. 167-173
-
-
Saji, M.1
Vasko, V.2
Kada, F.3
Allbritton, E.H.4
Burman, K.D.5
Ringel, M.D.6
-
58
-
-
34047138426
-
Real-time imaging nuclear translocation of Akt1 in HCC cells
-
Zhu L., Hu C., Li J., Xue P., He X., Ge C., et al. Real-time imaging nuclear translocation of Akt1 in HCC cells. Biochem. Biophys. Res. Commun. 356 4 (2007 May 18) 1038-1043
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.356
, Issue.4
, pp. 1038-1043
-
-
Zhu, L.1
Hu, C.2
Li, J.3
Xue, P.4
He, X.5
Ge, C.6
-
59
-
-
1842863901
-
Aktion in the nucleus
-
Webster K.A. Aktion in the nucleus. Circ. Res. 94 7 (2004 Apr 16) 856-859
-
(2004)
Circ. Res.
, vol.94
, Issue.7
, pp. 856-859
-
-
Webster, K.A.1
-
60
-
-
0034647674
-
Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors
-
Borgatti P., Martelli A.M., Bellacosa A., Casto R., Massari L., Capitani S., et al. Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors. FEBS Lett. 477 1-2 (2000 Jul 14) 27-32
-
(2000)
FEBS Lett.
, vol.477
, Issue.1-2
, pp. 27-32
-
-
Borgatti, P.1
Martelli, A.M.2
Bellacosa, A.3
Casto, R.4
Massari, L.5
Capitani, S.6
-
61
-
-
14844357714
-
Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation
-
Scheid M.P., Parsons M., and Woodgett J.R. Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation. Mol. Cell. Biol. 25 6 (2005 Mar) 2347-2363
-
(2005)
Mol. Cell. Biol.
, vol.25
, Issue.6
, pp. 2347-2363
-
-
Scheid, M.P.1
Parsons, M.2
Woodgett, J.R.3
-
62
-
-
14844337006
-
Evaluation of left ventricular function in cardiomyopathic mice by tissue Doppler and color M-mode Doppler echocardiography
-
Tsujita Y., Kato T., and Sussman M.A. Evaluation of left ventricular function in cardiomyopathic mice by tissue Doppler and color M-mode Doppler echocardiography. Echocardiography 22 3 (2005 Mar) 245-253
-
(2005)
Echocardiography
, vol.22
, Issue.3
, pp. 245-253
-
-
Tsujita, Y.1
Kato, T.2
Sussman, M.A.3
|