JAK/STAT and PI3K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytes

Cellular Physiology and Biochemistry

Volumn 21, Issue 4, 2008, Pages 305-314

  Lu, Yanjie ^a   Zhou, Jin ^a   Xu, Chaoqian ^a   Lin, Huixian ^a,b,c   Xiao, Jiening ^a,b,c   Wang, Zhiguo ^a,b,c   Yang, Baofeng ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b MONTREAL HEART INSTITUTE   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Apoptosis; Cardiomyocytes; JAK2 STAT3; NF B; PI3K AKT; Signaling pathway

Indexed keywords

HYDROGEN PEROXIDE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; JANUS KINASE 2; JANUS KINASE INHIBITOR; OLIGONUCLEOTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; STAT PROTEIN; STAT3 PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL POPULATION; CELL STRESS; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE CELL; MITOSIS; NEWBORN; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION; WESTERN BLOTTING;

RATTUS;

EID: 42549116145     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000129389     Document Type: Article

References (33)