The Feverfew plant-derived compound, parthenolide enhances platelet production and attenuates platelet activation through NF-κB inhibition

Thrombosis Research

Volumn 127, Issue 5, 2011, Pages 426-434

  Sahler, Julie ^a   Bernard, Jamie J ^b   Spinelli, Sherry L ^a   Blumberg, Neil ^a   Phipps, Richard P ^a,c  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Parthenolide; Platelet activation; Thrombopoiesis

Indexed keywords

CD40 LIGAND; COLLAGEN; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PADGEM PROTEIN; PARTHENOLIDE; REACTIVE OXYGEN METABOLITE; THROMBIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL LEVEL; CELL STIMULATION; EX VIVO STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MEGAKARYOBLAST; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTOPOIESIS; TRANSCRIPTION REGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOOD PLATELETS; CELL LINE; HUMANS; MEGAKARYOCYTE PROGENITOR CELLS; MICE; MICE, INBRED C57BL; NF-KAPPA B; PLATELET ACTIVATION; SESQUITERPENES; TANACETUM PARTHENIUM;

EID: 79955478936     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2010.12.013     Document Type: Article

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