Regulation of MT1-MMP and MMP-2 by leptin in cardiac fibroblasts involves Rho/ROCK-dependent actin cytoskeletal reorganization and leads to enhanced cell migration

Endocrinology

Volumn 152, Issue 5, 2011, Pages 2037-2047

  Schram, Kristin ^a   Ganguly, Riya ^a   No, Eun Kyung ^a   Fang, Xiangping ^a   Thong, Farah S L ^a   Sweeney, Gary ^a,b  

^a YORK UNIVERSITY   (Canada)

^b Institute Pasteur Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 5 BROMO 2 DEOXY URIDINE; ACTIN; ANTIBODY; COFILIN; EPITOPE; GELATINASE A; HERMES ANTIGEN; LEPTIN; MATRIX METALLOPROTEINASE 14; PHALLOIDIN; RHO ASSOCIATED COILED COIL FORMING PROTEIN KINASE; RHO KINASE; RHODAMINE; UNCLASSIFIED DRUG; URIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASSAY; CARDIAC FIBROBLAST; CELL ASSAY; CELL MIGRATION; CELL PROLIFERATION; CELL SURFACE BIOTINYLATION ASSAY; CENTRIFUGATION; COLORIMETRY; CONNECTIVE TISSUE CELL; CONTROLLED STUDY; CYTOSKELETAL REORGANIZATION; CYTOSKELETON; DIFFERENTIAL CENTRIFUGATION; GELATIN ZYMOGRAPHY; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MALE; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RAT; SIGNAL TRANSDUCTION; STRESS FIBER; WOUND SCRATCH ASSAY; ZYMOGRAPHY;

ACTINS; AMIDES; ANIMALS; BLOTTING, WESTERN; CELL MOVEMENT; CELLS, CULTURED; CYTOSKELETON; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FIBROBLASTS; IMMUNOPRECIPITATION; LEPTIN; MALE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASES; MICROSCOPY, CONFOCAL; MYOCARDIUM; PHOSPHORYLATION; PYRIDINES; RATS; RATS, WISTAR; RHO-ASSOCIATED KINASES; TIME FACTORS;

EID: 79955459948     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-1166     Document Type: Article

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