Paradigmatic identification of MMP-2 and MT1-MMP activation systems in cardiac fibroblasts cultured as a monolayer

Journal of Cellular Biochemistry

Volumn 94, Issue 3, 2005, Pages 446-459

  Guo, Chun ^a,b   Jiang, Juwei ^a   Elliott, J Martin ^a   Piacentini, Lucia ^a  

^a DE MONTFORT UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cardiac fibroblasts; Concanavalin A; Furin; MMP 2; MT1 MMP; TIMP 2

Indexed keywords

CELL PROTEIN; COLLAGEN TYPE 1; CONCANAVALIN A; FURIN; GELATINASE A; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE; METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST CULTURE; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; MONOLAYER CULTURE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT; SPECIES IDENTIFICATION; WOUND HEALING; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; ENZYMOLOGY; HEART MUSCLE; METABOLISM; UPREGULATION;

ANIMALS; CELLS, CULTURED; FURIN; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; MYOCARDIUM; RATS; TISSUE INHIBITOR OF METALLOPROTEINASE-2; UP-REGULATION;

EID: 22544463011     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20272     Document Type: Article

References (44)

1. Allenberg M, Weinstein T, Li I, Silverman M. 1994. Activation of procollagenase IV by cytochalasin D and concanavalin A in cultured rat mesangial cells: Linkage to cytoskeletal reorganization. J Am Soc Nephrol 4:1760-1770.
2. Bergman MR, Cheng S, Honbo N, Piacentini L, Karliner JS, Lovett DH. 2003. A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers. Biochem J 369:485-496.
3. Bigg HF, Shi YE, Liu YE, Steffensen B, Overall CM. 1997. Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2. J Biol Chem 272:15496-15500.
4. Bigg HF, Morrison CJ, Butler GS, Bogoyevitch MA, Wang Z, Soloway PD, Overall CM. 2001. Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase. Cancer Res 61:3610-3618.
5. 3. Cell 85:683-693.
6. Butler GS, Butler MJ, Atkinson SJ, Will H, Tamura T, van Westrum SS, Crabbe T, Clements J, d'Ortho MP, Murphy G. 1998. The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J Biol Chem 273:871-880.
7. Cao J, Rehemtulla A, Bahou W, Zucker S. 1996. Membrane type matrix metalloproteinase 1 activates pro-gelatinase A without furin cleavage of the N-terminal domain. J Biol Chem 271:30174-30180.
8. Creemers EE, Cleutjens JP, Smits JF, Daemen MJ. 2001. Matrix metalloproteinase inhibition after myocardial infarction: A new approach to prevent heart failure? Circ Res 89:201-210.
9. Deryugina EI, Bourdon MA, Luo GX, Reisfeld RA, Strongin A. 1997. Matrix metalloproteinase-2 activation modulates glioma cell migration. J Cell Sci 110:2473-2482.
10. v subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase. J Biol Chem 277:9749-9756.
11. Foda HD, George S, Rollo E, Drews M, Conner C, Cao J, Panettieri RA, Jr., Zucker S. 1999. Regulation of gelatinases in human airway smooth muscle cells: Mechanism of progelatinase A activation. Am J Physiol 277: L174-L182.
12. Gervasi DC, Raz A, Dehem M, Yang M, Kurkinen M, Fridman R. 1996. Carbohydrate-mediated regulation of matrix metalloproteinase-2 activation in normal human fibroblasts and fibrosarcoma cells. Biochem Biophys Res Commun 228:530-538.
13. Greene J, Wang M, Liu YE, Raymond LA, Rosen C, Shi YE. 1996. Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4. J Biol Chem 271:30375-30380.
14. Guo C, Piacentini L. 2003. Type I collagen-induced MMP-2 activation coincides with up-regulation of membrane type 1-matrix metalloproteinase and TIMP-2 in cardiac fibroblasts. J Biol Chem 278:46699-46708.
15. Harayama T, Ohuchi E, Aoki T, Sato H, Seiki M, Okada Y. 1999. Shedding of membrane type 1 matrix metalloproteinase in a human breast carcinoma cell line. Jpn J Cancer Res 90:942-950.
16. Hernandez-Barrantes S, Toth M, Bernardo MM, Yurkova M, Gervasi DC, Raz Y, Sang QA, Fridman R. 2000. Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation. J Biol Chem 275:12080-12089
17. Hotary K, Allen E, Punturieri A, Yana I, Weiss SJ. 2000. Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J Cell Biol 149:1309-1323.
18. Itoh Y, Ito A, Iwata K, Tanzawa K, Mori Y, Nagase H. 1998. Plasma membrane-bound tissue inhibitor of metalloproteinases (TIMP)-2 specifically inhibits matrix metalloproteinase 2 (gelatinase A) activated on the cell surface. J Biol Chem 273:24360-24367.
19. Jiang A, Lehti K, Wang X, Weiss SJ, Keski-Oja J, Pei D. 2001. Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis. Proc Natl Acad Sci USA 98:13693-13698.
20. Kleiner DE, Stetler-Stevenson WG. 1994. Quantitative zymography: Detection of picogram quantities of gelatinases. Anal Biochem 218:325-329.
21. Leco KJ, Apte SS, Taniguchi GT, Hawkes SP, Khokha R, Schultz GA, Edwards DR. 1997. Murine tissue inhibitor of metalloproteinases-4 (Timp-4): cDNA isolation and expression in adult mouse tissues. FEBS Lett 401:213-217.
22. Lohi J, Lehti K, Westermarck J, Kahari VM, Keski-Oja J. 1996. Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate. Eur J Biochem 239(2):239-247.
23. Maquoi E, Noel A, Frankenne F, Angliker H, Murphy G, Foidart JM. 1998. Inhibition of matrix metalloproteinase 2 maturation and HT1080 invasiveness by a synthetic furin inhibitor. FEBS Lett 424:262-266.
24. Maquoi E, Frankenne F, Baramova E, Munaut C, Sounni NE, Remade A, Noel A, Murphy G, Foidart JM. 2000a. Membrane type 1 matrix metalloproteinase- associated degradation of tissue inhibitor of metalloproteinase 2 in human tumor cell lines. J Biol Chem 275:11368-11378.
25. Maquoi E, Frankenne F, Noel A, Krell HW, Grams F, Foidart JM. 2000b. Type IV collagen induces matrix metalloproteinase 2 activation in HT1080 fibrosarcoma cells. Exp Cell Res 261:348-359.
26. Nagase H, Woessner JF, Jr. 1999. Matrix metalloproteinases. J Biol 274:21491-21494.
27. Okada A, Tomasetto C, Lutz Y, Bellocq JP, Rio MC, Basset P. 1997. Expression of matrix metalloproteinases during rat skin wound healing: Evidence that membrane type-1 matrix metalloproteinase is a stromal activator of progelatinase A. J Cell Biol 137:67-77.
28. Oliver GW, Leferson JD, Stetler-Stevenson WG, Kleiner DE. 1997. Quantitative reverse zymography: Analysis of picogram amounts of metalloproteinase inhibitors using gelatinase A and B reverse zymograms. Anal Biochem 244:161-166.
29. Ono K, Matsumori A, Shioi T, Furukawa Y, Sasayama S. 1998. Cytokine gene expression after myocardial infarction in rat hearts: Possible implication in left ventricular remodeling. Circulation 98:149-156.
30. Pei D, Rang T, Qi H. 2000. Cysteine array matrix metalloproteinase (CA-MMP)/MMP-23 is a type II transmembrane matrix metalloproteinase regulated by a single cleavage for both secretion and activation. J Biol Chem 275:33988-33997.
31. Ratnikov BI, Rozanov DV, Postnova TI, Baciu PG, Zhang H, DiScipio RG, Chestukhina GG, Smith JW, Deryugina EI, Strongin AY. 2002. An alternative processing of integrin alpha(v) subunit in tumor cells by membrane type-1 matrix metalloproteinase. J Biol Chem 277:7377-7385.
32. Remacle A, Murphy G, Roghi C. 2003. Membrane type I-matrix metalloproteinase (MT1-MMP) is internalised by two different pathways and is recycled to the cell surface. J Cell Sci 116:3905-3916.
33. Rohde LE, Ducharme A, Arroyo LH, Aikawa M, Sukhova GH, Lopez-Anaya A, McClure KF, Mitchell PG, Libby P, Lee RT. 1999. Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice. Circulation 99:3063-3070.
34. Rosenblith JZ, Ukena TE, Yin HH, Berlin RD, Karnovsky MJ. 1973. A comparative evaluation of the distribution of concanavalin A-binding sites on the surfaces of normal, virally-transformed, and protease-treated fibroblasts. Proc Natl Acad Sci USA 70:1625-1629.
35. Rozanov DV, Deryugina EI, Ratnikov BI, Monosov EZ, Marchenko GN, Quigley JP, Strongin AY. 2001. Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells. J Biol Chem 276:25705-25714.
36. Sato T, Kondo T, Fujisawa T, Seiki M, Ito A. 1999. Furin-independent pathway of membrane type 1-matrix metalloproteinase activation in rabbit dermal flbroblasts. J Biol Chem 274:37280-37284.
37. Seiki M, Yana I. 2003. Roles of pericellular proteolysis by membrane type-1 matrix metalloproteinase in cancer invasion and angiogenesis. Cancer Sci 94:569-574.
38. Shofuda K, Moriyama K, Nishihashi A, Higashi S, Mizushima H, Yasumitsu H, Miki K, Sato H, Seiki M, Miyazaki K. 1998. Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells. J Biochem (Tokyo) 124:462-470.
39. Siwik DA, Chang DL, Colucci WS. 2000. Interleukin-1β and tumor necrosis factor-α decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac flbroblasts in vitro. Circ Res 86:1259-1265.
40. Strongin AY, Collier I, Bannikov G, Marmer BL, Grant GA, Goldberg GI. 1995. Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J Biol Chem 270:5331-5338.
41. Ward RV, Atkinson SJ, Reynolds JJ, Murphy G. 1994. Cell surface-mediated activation of progelatinase A: Demonstration of the involvement of the C-terminal domain of progelatinase A in cell surface binding and activation of progelatinase A by primary flbroblasts. Biochem J 304:263-269.
42. Weber KT. 1997. Extracellular matrix remodeling in heart failure: A role for de novo angiotensin II generation. Circulation 96:4065-4082.
43. Yana I, Weiss SJ. 2000. Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases. Mol Biol Cell 11:2387-2401.
44. Yue P, Massie BM, Simpson PC, Long CS. 1998. Cytokine expression increases in nonmyocytes from rats with postinfarction heart failure. Am J Physiol 275:H250-H258.