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Volumn 5, Issue 6, 1999, Pages 1539-1549

125I-labeled anti-epidermal growth factor receptor-vIII single-chain Fv exhibits specific and high-level targeting of glioma xenografts

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY CONJUGATE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; IODINE 125; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY H10; MONOCLONAL ANTIBODY L8A4; UNCLASSIFIED DRUG; RADIOACTIVE IODINE;

EID: 0032586898     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (56)

References (57)
  • 3
    • 0030007734 scopus 로고    scopus 로고
    • Recombinant antibody fusion proteins for cancer immunotherapy
    • Reisfeld, R. A., and Gillies, S. D. Recombinant antibody fusion proteins for cancer immunotherapy. Curr. Top. Microbiol. Immunol., 213: 27-53, 1996.
    • (1996) Curr. Top. Microbiol. Immunol. , vol.213 , pp. 27-53
    • Reisfeld, R.A.1    Gillies, S.D.2
  • 12
    • 0031451777 scopus 로고    scopus 로고
    • Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors
    • Laske, D. W., Youle, R. J., and Oldfield, E. H. Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors. Nat. Med., 3: 1362-1368, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 1362-1368
    • Laske, D.W.1    Youle, R.J.2    Oldfield, E.H.3
  • 13
    • 0028843420 scopus 로고
    • Single-chain Fvs
    • Raag, R., and Whitlow, M. Single-chain Fvs. FASEB J., 9: 73-80, 1995.
    • (1995) FASEB J. , vol.9 , pp. 73-80
    • Raag, R.1    Whitlow, M.2
  • 14
    • 0026684815 scopus 로고
    • Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
    • Yokota, T., Milenic, D. E., Withlow, M., and Schlom, J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res., 52: 3402-3408, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 3402-3408
    • Yokota, T.1    Milenic, D.E.2    Withlow, M.3    Schlom, J.4
  • 16
    • 0026005994 scopus 로고
    • B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice
    • Brinkmann, U., Pai, L. H., FitzGerald, D. J., Willingham, M., and Pastan, I. B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice. Proc. Natl. Acad. Sci. USA, 88: 8616-8620, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8616-8620
    • Brinkmann, U.1    Pai, L.H.2    Fitzgerald, D.J.3    Willingham, M.4    Pastan, I.5
  • 18
    • 0027312336 scopus 로고
    • Bacterial expression of immunoglobulin fragments
    • Skerra, A. Bacterial expression of immunoglobulin fragments. Curr. Opin. Immunol., 5: 256-262, 1993.
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 256-262
    • Skerra, A.1
  • 20
    • 0024232289 scopus 로고
    • Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure
    • Jain, R., and Baxter, L. Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure. Cancer Res., 48: 7022-7033, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 7022-7033
    • Jain, R.1    Baxter, L.2
  • 21
    • 0026327378 scopus 로고
    • Construction, binding properties, metabolism, and tumor targeting of a single chain Fv derived from the pancarcinoma monoclonal antibody CC49
    • Milenic, D. E., Yokota, T., Filpula, D. R., Finkelman, M. A. J., Dodd, S. W., Wood, J. F., Withlow, M., Snoy, P., and Schlom, J. Construction, binding properties, metabolism, and tumor targeting of a single chain Fv derived from the pancarcinoma monoclonal antibody CC49. Cancer Res., 51: 6363-6371, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 6363-6371
    • Milenic, D.E.1    Yokota, T.2    Filpula, D.R.3    Finkelman, M.A.J.4    Dodd, S.W.5    Wood, J.F.6    Withlow, M.7    Snoy, P.8    Schlom, J.9
  • 22
    • 0025686126 scopus 로고
    • Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts
    • Bigner, S. H., Humphrey, P. A., Wong, A. J., Vogelstein, B., Mark, J., Friedman, H. S., and Bigner, D. D. Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts. Cancer Res., 50: 8017-8022, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 8017-8022
    • Bigner, S.H.1    Humphrey, P.A.2    Wong, A.J.3    Vogelstein, B.4    Mark, J.5    Friedman, H.S.6    Bigner, D.D.7
  • 23
    • 0025111441 scopus 로고
    • A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumors
    • Yamazaki, H., Ohba, Y., Tamaoki, N., and Shibuya, M. A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumors. Jpn. J. Cancer Res., 81: 773-779, 1990.
    • (1990) Jpn. J. Cancer Res. , vol.81 , pp. 773-779
    • Yamazaki, H.1    Ohba, Y.2    Tamaoki, N.3    Shibuya, M.4
  • 28
    • 0028863853 scopus 로고
    • Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene
    • Batra, S. K., Castelino-Prabhu, S., Wikstrand, C. J., Zhu, X., Humphrey, P. A., Friedman, H. S., and Bigner, D. D. Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene. Cell Growth Differ., 6: 1251-1259, 1995.
    • (1995) Cell Growth Differ. , vol.6 , pp. 1251-1259
    • Batra, S.K.1    Castelino-Prabhu, S.2    Wikstrand, C.J.3    Zhu, X.4    Humphrey, P.A.5    Friedman, H.S.6    Bigner, D.D.7
  • 30
    • 0029961911 scopus 로고    scopus 로고
    • Radioiodination of internalizing monoclonal antibodies using N-succinimidyl 5-iodo-3-pyridinecarboxylate
    • Reist, C. J., Garg, P. K., Alston, K. L., Bigner, D. D., and Zalutsky, M. R. Radioiodination of internalizing monoclonal antibodies using N-succinimidyl 5-iodo-3-pyridinecarboxylate. Cancer Res., 56: 4970-4977, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 4970-4977
    • Reist, C.J.1    Garg, P.K.2    Alston, K.L.3    Bigner, D.D.4    Zalutsky, M.R.5
  • 31
    • 0030983005 scopus 로고    scopus 로고
    • Improved targeting of an anti-epidermal growth factor receptor variant III monoclonal antibody in tumor xenografts after labeling using N-succinimidyl 5-iodo-3-pyridinecarboxylate
    • Reist, C. J., Archer, G. E., Wikstrand, C. J., Bigner, D. D., and Zalutsky, M. R. Improved targeting of an anti-epidermal growth factor receptor variant III monoclonal antibody in tumor xenografts after labeling using N-succinimidyl 5-iodo-3-pyridinecarboxylate. Cancer Res., 57: 1510-1515, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 1510-1515
    • Reist, C.J.1    Archer, G.E.2    Wikstrand, C.J.3    Bigner, D.D.4    Zalutsky, M.R.5
  • 32
    • 0029857998 scopus 로고    scopus 로고
    • Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: Targeting with a single chain antibody variable domain isolated by phage display
    • Lorimer, I. A., Keppler-Hafkemeyer, A., Beers, R. A., Pegram, C. N., Bigner, D. D., and Pastan, I. Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: targeting with a single chain antibody variable domain isolated by phage display. Proc. Natl. Acad. Sci. USA, 93: 14815-14820, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14815-14820
    • Lorimer, I.A.1    Keppler-Hafkemeyer, A.2    Beers, R.A.3    Pegram, C.N.4    Bigner, D.D.5    Pastan, I.6
  • 33
    • 0031929068 scopus 로고    scopus 로고
    • Intratumour injection of immunoglobulins labelled with the α-particle emitter 211At: Analyses of tumour retention, microdistribution and growth delay
    • Larsen, R. H., and Bruland, O. S. Intratumour injection of immunoglobulins labelled with the α-particle emitter 211At: analyses of tumour retention, microdistribution and growth delay. Br. J. Cancer, 77: 1115-1122, 1998.
    • (1998) Br. J. Cancer , vol.77 , pp. 1115-1122
    • Larsen, R.H.1    Bruland, O.S.2
  • 35
    • 0030876425 scopus 로고    scopus 로고
    • Intralesional radiolabeled human monoclonal IgM in human tumor xenografts
    • Borchardt, P. E., Quadri, S. M., Freedman, R. S., and Vriesendorp, H. M. Intralesional radiolabeled human monoclonal IgM in human tumor xenografts. Radiother. Oncol., 44: 283-293, 1997.
    • (1997) Radiother. Oncol. , vol.44 , pp. 283-293
    • Borchardt, P.E.1    Quadri, S.M.2    Freedman, R.S.3    Vriesendorp, H.M.4
  • 37
    • 0021236693 scopus 로고
    • Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess
    • Lindmo, T., Boven, E., Cuttitta, F., Fedorko, J., and Bunn, P., Jr. Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess. J. Immunol. Methods, 72: 77-89, 1984.
    • (1984) J. Immunol. Methods , vol.72 , pp. 77-89
    • Lindmo, T.1    Boven, E.2    Cuttitta, F.3    Fedorko, J.4    Bunn P., Jr.5
  • 38
    • 0030787340 scopus 로고    scopus 로고
    • Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII)
    • Chu, C. T., Everiss, K. D., Wikstrand, C. J., Batra, S. K., Kung, H. J., and Bigner, D. D. Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII). Biochem. J., 324: 855-861, 1997.
    • (1997) Biochem. J. , vol.324 , pp. 855-861
    • Chu, C.T.1    Everiss, K.D.2    Wikstrand, C.J.3    Batra, S.K.4    Kung, H.J.5    Bigner, D.D.6
  • 40
    • 14744298086 scopus 로고
    • Construction, bacterial expression and characterization of a bifunctional single-chain antibody-phosphatase fusion protein targeted to the human erbB-2 receptor
    • Wels, W., Harwerth, I. M., Zwickl, M., Hardman, N., Groner, B., and Hynes, N. E. Construction, bacterial expression and characterization of a bifunctional single-chain antibody-phosphatase fusion protein targeted to the human erbB-2 receptor. Biotechnology, 10: 1128-1132, 1992.
    • (1992) Biotechnology , vol.10 , pp. 1128-1132
    • Wels, W.1    Harwerth, I.M.2    Zwickl, M.3    Hardman, N.4    Groner, B.5    Hynes, N.E.6
  • 41
    • 0027197493 scopus 로고
    • "Diabodies": Small bivalent and bispecific antibody fragments
    • Holliger, P., Prospero, T., and Winter, G. "Diabodies": small bivalent and bispecific antibody fragments. Proc. Natl. Acad. Sci. USA, 90: 6444-6448, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6444-6448
    • Holliger, P.1    Prospero, T.2    Winter, G.3
  • 43
    • 0029890636 scopus 로고    scopus 로고
    • Minibody. A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts
    • Hu, S., Shively, L., Raubitschek, A., Sherman, M., Williams, L. E., Wong, J. Y., Shively, J. E., and Wu, A. M. Minibody. A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts. Cancer Res., 56: 3055-3061, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 3055-3061
    • Hu, S.1    Shively, L.2    Raubitschek, A.3    Sherman, M.4    Williams, L.E.5    Wong, J.Y.6    Shively, J.E.7    Wu, A.M.8
  • 44
    • 0025826197 scopus 로고
    • Characterization of monoclonal antibodies B1 and B3 that react with mucinous adenocarcinomas
    • Pastan, I., Lovelace, E. T., Gallo, M. G., Rutherford, A. V., Magnani, J. L., and Willingham, M. C. Characterization of monoclonal antibodies B1 and B3 that react with mucinous adenocarcinomas. Cancer Res., 51: 3781-3787, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 3781-3787
    • Pastan, I.1    Lovelace, E.T.2    Gallo, M.G.3    Rutherford, A.V.4    Magnani, J.L.5    Willingham, M.C.6
  • 47
    • 0030818101 scopus 로고    scopus 로고
    • In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: Comparison with its murine parent
    • Reist, C. J., Batra, S. K., Pegram, C. N., Bigner, D. D., and Zalutsky, M. R. In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: comparison with its murine parent. Nucl. Med. Biol., 24: 637-647, 1997.
    • (1997) Nucl. Med. Biol. , vol.24 , pp. 637-647
    • Reist, C.J.1    Batra, S.K.2    Pegram, C.N.3    Bigner, D.D.4    Zalutsky, M.R.5
  • 49
    • 0029031155 scopus 로고
    • Improved tumor radioimmunodetection using a single-chain Fv and γ-interferon: Potential clinical applications for radioimmunoguided surgery and γ scanning
    • Nieroda, C. A., Milenic, D. E., Carrasquillo, J. A., Scholm, J., and Greiner, J. W. Improved tumor radioimmunodetection using a single-chain Fv and γ-interferon: potential clinical applications for radioimmunoguided surgery and γ scanning. Cancer Res., 55: 2858-2865, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 2858-2865
    • Nieroda, C.A.1    Milenic, D.E.2    Carrasquillo, J.A.3    Scholm, J.4    Greiner, J.W.5
  • 51
    • 0028843174 scopus 로고
    • Rapid and specific uptake of anti-Tac disulfide-stabilized Fv by interleukin-2 receptor-bearing tumors
    • Webber, K. O., Kreitman, R. J., and Pastan, I. Rapid and specific uptake of anti-Tac disulfide-stabilized Fv by interleukin-2 receptor-bearing tumors. Cancer Res., 55: 318-323, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 318-323
    • Webber, K.O.1    Kreitman, R.J.2    Pastan, I.3
  • 55
    • 0029001712 scopus 로고
    • Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion
    • Lieberman, D. M., Laske, D. W., Morrison, P. F., Bankiewicz, K. S., and Oldfield, E. H. Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion. J. Neurosurg., 82: 1021-1029, 1995.
    • (1995) J. Neurosurg. , vol.82 , pp. 1021-1029
    • Lieberman, D.M.1    Laske, D.W.2    Morrison, P.F.3    Bankiewicz, K.S.4    Oldfield, E.H.5
  • 56
    • 0029927443 scopus 로고    scopus 로고
    • Intratumoral radioimmunotherapy of a human colon cancer xenograft using a sustained-release gel
    • Ning, S., Trisler, K., Brown, D. M., Yu, N. Y., Kanekal, S., Lundsten, M. J., and Knox, S. J. Intratumoral radioimmunotherapy of a human colon cancer xenograft using a sustained-release gel. Radiother. Oncol., 39: 179-189, 1996.
    • (1996) Radiother. Oncol. , vol.39 , pp. 179-189
    • Ning, S.1    Trisler, K.2    Brown, D.M.3    Yu, N.Y.4    Kanekal, S.5    Lundsten, M.J.6    Knox, S.J.7
  • 57
    • 0025743924 scopus 로고
    • Uptake and distribution of specific and control monoclonal antibodies in subcutaneous xenografts following intratumor injection
    • Rowlinson-Busza, G., Bamias, A., Krausz, T., and Epenetos, A. A., Uptake and distribution of specific and control monoclonal antibodies in subcutaneous xenografts following intratumor injection. Cancer Res., 51: 3251-3256, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 3251-3256
    • Rowlinson-Busza, G.1    Bamias, A.2    Krausz, T.3    Epenetos, A.A.4


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