Pharmacology in health foods: Effects of arachidonic acid and docosahexaenoic acid on the age-related decline in brain and cardiovascular system function

Journal of Pharmacological Sciences

Volumn 115, Issue 4, 2011, Pages 471-475

  Kiso, Yoshinobu ^a  

^a Suntory Wellness Limited Research Center   (Japan)

Author keywords

Age related decline; Arachidonic acid; Brain function; Cardiovascular system; Docosahexaenoic acid; Health food

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; PLACEBO; POLYUNSATURATED FATTY ACID;

ACTION POTENTIAL; AGE; BRAIN DAMAGE; BRAIN FUNCTION; BRAIN PROTECTION; CARDIOVASCULAR FUNCTION; CLINICAL EFFECTIVENESS; COGNITIVE DEFECT; CORONARY ARTERY BLOOD FLOW; CORONARY FLOW RESERVE; DIET SUPPLEMENTATION; DISEASE SEVERITY; DRUG EFFICACY; DRUG MECHANISM; ENDOTHELIAL DYSFUNCTION; EVENT RELATED POTENTIAL; FOOD INTAKE; HEALTH FOOD; HEART PROTECTION; HUMAN; JAPANESE; LATENT PERIOD; MICROCIRCULATION; NERVE CELL PLASTICITY; NONHUMAN; SHORT SURVEY; THERAPY EFFECT; VASCULAR ENDOTHELIUM;

EID: 79955038914     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10R39FM     Document Type: Short Survey

References (28)

1. McGahon B, Clements MP, Lynch MA. The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed. Neuroscience. 1997;81:9-16. (Pubitemid 27373623)
2. McGahon B, Maguire C, Kelly A, Lynch MA. Activation of p42 mitogen-activated protein kinase by arachidonic acid and trans-1-amino- cyclopentyl-1,3-dicarboxylate impacts on long-term potentiation in the dentate gyrus in the rat: analysis of age-related changes. Neuroscience. 1999;90:1167-1175.
3. McGahon BM, Martin DS, Horrobin DF, Lynch MA. Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids. Neuroscience. 1999; 94:305-314. (Pubitemid 29457620)
4. McGahon BM, Martin DS, Horrobin DF, Lynch MA. Age-related changes in LTP and antioxidant defenses are reversed by an alpha-lipoic acid-enriched diet. Neurobiol. Aging. 1999;20:655-664.
5. McGahon BM, Murray CA, Horrobin DF, Lynch MA. Age-related changes in oxidative mechanisms and LTP are reversed by dietary manipulation. Neurobiol. Aging. 1999;20:643-653.
6. Sakuradani E, Kobayashi M, Shimizu S. Δ9-Fatty acid desaturase from arachidonic acid-producing fungus: unique gene sequence and its heterologous expression in a fungus. Eur J Biochem. 1999;260:208-216.
7. Nelson GJ, Kelley DS, Emken EA, Phinney SD, Kyle D, Ferretti A. A human dietary arachidonic acid supplementation study conducted in a metabolic research unit: rational and design. Lipids. 1997;32:415-420. (Pubitemid 27173069)
8. Nelson GJ, Schmidt PC, Bartolini G, Kelley DS, Kyle D. The effect of dietary arachidonic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids. 1997;32:421-425. (Pubitemid 27173070)
9. Nelson GJ, Schmidt PC, Bartolini G, Kelley DS, Phinney SD, Kyle D, et al. The effect of dietary arachidonic acid on plasma lipoprotein distributions, apoproteins, blood lipid levels, and tissue fatty acid composition in humans. Lipids. 1997;32:427-433. (Pubitemid 27173071)
10. Kusumoto A, Ishikura Y, Kawashima H, Kiso Y, Takai S, Miyazaki M. Effects of arachidonate-enriched triacylglycerol supplementation on serum fatty acids and platelet aggregation in healthy male subjects with a fish diet. Br J Nutr. 2007;98: 626-635. (Pubitemid 47277259)
11. Kotani S, Nakazawa H, Tokimasa T, Akimoto K, Kawashima H, Toyoda-Ono Y, et al. Synaptic plasticity preserved with arachidonic acid diet in aged rats. Neurosci Res. 2003;46:453-461. (Pubitemid 36842796)
12. Polich J. P300 in the evaluation of aging and dementia. In: Brunia CHM, Mulder G, Verbaten MN, editors. Event-related brain potential research. EEG Suppl. Amsterdam: Elsevier; 1991. p. 304-323.
13. Polich J. Meta-analysis of P300 normative aging studies. Psychophysiology. 1996;33:334-353. (Pubitemid 26230719)
14. Polich J, Ladish C, Burns T. Normal variation of P300 in children: age, memory span, and head size. Int J Psychophysiol. 1990;9:237-248. (Pubitemid 20343139)
15. Hirayasu Y, Samura M, Ohta H, Ogura C. Sex effects on rate of change of P300 latency with age. Clin Neurophysiol. 2000;111: 187-194. (Pubitemid 30009432)
16. Ishikura Y, Ikeda G, Akimoto K, Hata M, Kusumoto A, Kidokoro A, et al. Arachidonic acid supplementation decreases P300 latency and increases P300 amplitude of event-related potentials in healthy elderly men. Neuropsychobiology. 2009;60:73-79.
17. Randolph C, Tierney MC, Mohr E, Chase TN. The repeatable battery for the assessment of neuropsychological status (RBANS): preliminary clinical validity. J Clin Exp Neuropsychol. 1998; 20:310-319. (Pubitemid 28539551)
18. Yamashima T, Yoshida M, Kumahashi K, Matsui M, Koshino Y, Higashima M, et al. [The Japanese version of RBANS (repeatable battery for the assessment of neuropsychological status)]. No To Shinkei. 2002;54:463-471. (text in Japanese with English abstract)
19. Kotani S, Sakaguchi E, Warashina S, Matsukawa N, Ishikura Y, Kiso Y, et al. Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction. Neurosci Res. 2006;56:159-164. (Pubitemid 44374788)
20. Nakano D, Ishii F, Fujii K, Ishikura Y, Akimoto K, Kontani M, et al. Effects of dietary arachidonic acid supplementation on age-related changes in endothelium-dependent vascular responses. J Nutr Sci Vitaminol. 2006;53:75-81.
21. Hu FB, Willett WC. Optimal diets for prevention of coronary heart disease. JAMA. 2002;288:2569-2578. (Pubitemid 35386892)
22. Laaksonen DE, Nyyssönen K, Niskanen L, Rissanen TH, Salonen JT. Prediction of cardiovascular mortality in middle-aged men by dietary and serum linoleic and polyunsaturated fatty acids. Arch Intern Med. 2005;165:193-199.
23. Albert CM, Campos H, Stampfer MJ, Ridker PM, Manson JE, Willett WC, et al. Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med. 2002;346:1113-1118. (Pubitemid 34984601)
24. GISSI-Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E in 11,324 patients with myocardial infarction: results of the GISSI-Prevenzione trial. Lancet. 1999;354:447-455.
25. Pischon T, Hankinson SE, Hotamisligil GS, Rifai N, Willett WC, Rimm EB. Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women. Circulation. 2003;108:155-160. (Pubitemid 36871296)
26. Demer LL, Gould KL, Goldstein RA, Kirkeeide RL, Mullani NA, Smalling RW, et al. Assessment of coronary artery disease severity by positron emission tomography. Comparison with quantitative arteriography in 193 patients. Circulation. 1989;79: 825-835.
27. Hozumi T, Yoshida K, Akasaka T, Asami Y, Ogata Y, Takagi T, et al. Noninvasive assessment of coronary flow velocity and coronary flow velocity reserve in the left anterior descending coronary artery by Doppler echocardiography: comparison with invasive technique. J Am Coll Cardiol. 1998;32:1251-1259. (Pubitemid 28522380)
28. Oe H, Hozumi T, Murata E, Matsuura H, Negishi K, Matsumura Y, et al. Arachidonic acid and docosahexaenoic acid supplementation increases coronary flow velocity reserve in Japanese elderly individuals. Heart. 2008;94:316-321. (Pubitemid 351303423)