Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction

Neuroscience Research

Volumn 56, Issue 2, 2006, Pages 159-164

  Kotani, Susumu ^a,b   Sakaguchi, Eiko ^a   Warashina, Shogo ^a   Matsukawa, Noriyuki ^c   Ishikura, Yoshiyuki ^d   Kiso, Yoshinobu ^d   Sakakibara, Manabu ^e   Yoshimoto, Tanihiro ^f   Guo, Jianzhong ^f   Yamashima, Tetsumori ^a,f  

^a Minamigaoka Hospital   (Japan)

^b Japan Foundation for Aging and Health   (Japan)

^c NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^d SUNTORY LTD   (Japan)

^e TOKAI UNIVERSITY   (Japan)

^f KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

Author keywords

Aging; Arachidonic acid; Cognitive dysfunction; Docosahexaenoic acid; Organic brain lesion

Indexed keywords

ARACHIDONIC ACID; ARAVITA; DOCOSAHEXAENOIC ACID; FATTY ACID; OLIVE OIL; PLACEBO;

ADULT; AGE; AGED; AGING; ALZHEIMER DISEASE; AMNESIA; ARTICLE; ATTENTION; BRAIN DAMAGE; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DIET SUPPLEMENTATION; EVALUATION; FEMALE; HIPPOCAMPUS; HUMAN; LIPID PEROXIDATION; LONG TERM POTENTIATION; MALE; NERVE CELL; ORGANIC BRAIN SYNDROME; PRIORITY JOURNAL; REPEATABLE BATTERY FOR ASSESSMENT OF NEUROPSYCHOLOGICAL STATUS; RODENT; SHORT TERM MEMORY;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ARACHIDONIC ACID; ATTENTION; BRAIN INJURIES; CASE-CONTROL STUDIES; COGNITION DISORDERS; DIETARY SUPPLEMENTS; DOCOSAHEXAENOIC ACIDS; FEMALE; HUMANS; JAPAN; MALE; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; REFERENCE VALUES;

EID: 33748534825     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2006.06.010     Document Type: Article

References (39)

1. Birch E.E., Garfield S., Hoffman D.R., Uauy R., and Birch D.G. A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants. Dev. Med. Child Neurol. 42 (2000) 174-181
2. Bliss T.V., and Lomo T. Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J. Physiol. 232 (1973) 331-356
3. Boston P.F., Bennett A., Horrobin D.F., and Bennett C.N. Ethyl-EPA in Alzheimer's disease-a pilot study. Prostaglandins Leukot Essent Fatty Acids 71 (2004) 341-346
4. Carlson S.E., and Werkman S.H. A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until 2 months. Lipids 31 (1996) 85-90
5. Champeil-Potokar G., Denis I., Goustard-Langelier B., Alessandri J.M., Guesnet P., and Lavialle M. Astrocytes in culture require docosahexaenoic acid to restore the n - 3/n - 6 polyunsaturated fatty acid balance in their membrane phospholipids. J. Neurosci. Res. 75 (2004) 96-106
6. Daw M.I., Chittajallu R., Bortolotto Z.A., Dev K.K., Duprat F., Henley J.M., Collingridge G.L., and Isaac J.T. PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses. Neuron 28 (2000) 873-886
7. Hama H., Hara C., Yamaguchi K., and Miyawaki A. PKC signaling mediates global enhancement of excitatory synaptogenesis in neurons triggered by local contact with astrocytes. Neuron 41 (2004) 405-415
8. Horrocks L.A., and Yeo Y.K. Health benefits of docosahexaenoic acid (DHA). Pharmacol. Res. 40 (1999) 211-225
9. Horrocks L.A., and Farooqui A.A. Docosahexaenoic acid in the diet: its importance in maintenance and restoration of neural membrane function. Prostaglandins Leukot Essent Fatty Acids 70 (2004) 361-372
10. Kotani S., Nakazawa H., Tokimasa T., Akimoto K., Kawashima H., Toyoda-Ono Y., Kiso Y., Okaichi H., and Sakakibara M. Synaptic plasticity preserved with arachidonic acid diet in aged rats. Neurosci. Res. 46 (2003) 453-461
11. Lu W., Man H., Ju W., Trimble W.S., MacDonald J.F., and Wang Y.T. Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons. Neuron 29 (2001) 243-254
12. Lynch M.A., and Voss K.L. Membrane arachidonic acid concentration correlates with age and induction of long-term potentiation in the dentate gyrus in the rat. Eur. J. Neurosci. 6 (1994) 1008-1014
13. Lynch M.A., Voss K.L., and Gower A.J. Impaired spatial memory in aged rats is associated with alterations in inositol phospholipid metabolism. Neuroreport 5 (1994) 1493-1497
14. Manev H., Uz T., Manev R., and Zhang Z. Neurogenesis and neuroprotection in the adult brain. A putative role for 5-lipoxygenase?. Ann. NY Acad. Sci. 939 (2001) 45-51
15. Martin D.S., Spencer P., Horrobin D.F., and Lynch M.A. Long-term potentiation in aged rats is restored when the age-related decrease in polyunsaturated fatty acid concentration is reversed. Prostaglandins Leukot Essent Fatty Acids 67 (2002) 121-130
16. McGahon B., Clements M.P., and Lynch M.A. The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed. Neuroscience 81 (1997) 9-16
17. McGahon B.M., Martin D.S., Horrobin D.F., and Lynch M.A. Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids. Neuroscience 94 (1999) 305-314
18. McKernan M.G., and Shinnick-Gallagher P. Fear conditioning induces a lasting potentiation of synaptic currents in vitro. Nature 390 (1997) 607-611
19. Muccioli G., Raso G.M., Ghe C., and Di Carlo R. Effect of L-alpha glycerylphosphorylcholine on muscarinic receptors and membrane micro viscosity of aged rat brain. Prog. Neuropsychopharmacol. Biol. Psychiatry 20 (1996) 323-339
20. Murray C.A., and Lynch M.A. Evidence that increased hippocampal expression of the cytokine interleukin-1 beta is a common trigger for age- and stress-induced impairments in long-term potentiation. J. Neurosci. 18 (1998) 2974-2981
21. Murray C.A., and Lynch M.A. Dietary supplementation with Vitamin E reverses the age-related deficit in long-term potentiation in dentate gyrus. J. Biol. Chem. 273 (1998) 12161-12168
22. Okaichi Y., Ishikura Y., Akimoto K., Kawashima H., Toyoda-Ono Y., Kiso Y., and Okaichi H. Arachidonic acid improves aged rats' spatial cognition. Physiol. Behav. 84 (2005) 617-623
23. Petersen R.C., Smith G.E., Waring S.C., Ivnik R.J., Tangalos E.G., and Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch. Neurol. 56 (1999) 303-308
24. Randolph C., Tierney M.C., Mohr E., and Chase T.N. The repeatable battery for the assessment of neuropsychological status (RBANS): preliminary clinical validity. J. Clin. Exp. Neuropsychol. 20 (1998) 310-319
25. Rogan M.T., Staubli U.V., and LeDoux J.E. Fear conditioning induces associative long-term potentiation in the amygdala. Nature 390 (1997) 604-607
26. Rosenzweig E.S., Rao G., McNaughton B.L., and Barnes C.A. Role of temporal summation in age-related long-term potentiation-induction deficits. Hippocampus 7 (1997) 549-558
27. Scheuer K., Rostock A., Bartsch R., and Muller W.E. Piracetam improves cognitive performance by restoring neurochemical deficits of the aged rat brain. Pharmacopsychiatry 32 Suppl. 1 (1999) 10-16
28. Soderberg M., Edlund C., Kristensson K., and Dallner G. Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease. Lipids 26 (1991) 421-425
29. Solfrizzi V., Panza F., Torres F., Mastroianni F., Del Parigi A., Venezia A., and Capurso A. High monounsaturated fatty acids intake protects against age-related cognitive decline. Neurology 52 (1999) 1563-1569
30. Song H., Stevens C.F., and Gage F.H. Astrogha induce neurogenesis from adult neural stem cells. Nature 417 (2002) 39-44
31. Song H.J., Stevens C.F., and Gage F.H. Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons. Nat. Neurosci. 5 (2002) 438-445
32. Tonchev A.B., Yamashima T., Zhao L., Okano H.J., and Okano H. Proliferation of neural and neuronal progenitors after global brain ischemia in young adult macaque monkeys. Mol. Cell. Neurosci. 42 (2003) 209-224
33. Tsukada H., KakiuchiT, Fukumoto D., Nishiyama S., and Koga K. Docosahexaenoic acid (DHA) improves the age-related impairment of the coupling mechanism between neuronal activation and functional cerebral blood flow response: a PET study in conscious monkeys. Brain Res. 862 (2000) 180-186
34. Uz T., Manev R., and Manev H. 5-Lipoxygenase is required for proliferation of immature cerebellar granule neurons in vitro. Eur. J. Pharmacol. 418 (2001) 15-22
35. van Praag H., Kempermann G., and Gage F.H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 2 (1999) 266-270
36. Yamashima T., Yoshida M., Kumahashi K., Matsui M., Koshino Y., Higashima M., Nagasawa T., Ueki A., Ohtsuka M., Aoki S., Imuro S., Mori N., Takei N., Hoshino R., Minabe Y., Nanba Y., Nanba M., Kira J., Ohyagi Y., Haraoka J., Akimoto J., Miura N., Kimura S., and Matsushita M. The Japanese version of RBANS (repeatable battery for the assessment of neuropsychological status). No To Shinkei 54 (2002) 463-471
37. Yehuda S., Rabinovitz S., Carasso R.L., and Mostofsky D.I. Fatty acids and brain peptides. Peptides 19 (1998) 407-419
38. Yehuda S., Rabinovitz S., Carasso R.L., and Mostofsky D.I. The role of polyunsaturated fatty acids in restoring the aging neuronal membrane. Neurobiol. Aging 23 (2002) 843-853
39. Zs-Nagy I. The membrane hypothesis of aging: its relevance to recent progress in genetic research. J. Mol. Med. 75 (1997) 703-714