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Volumn 3, Issue 1, 2011, Pages 17-29

Sesame seed lignans: Potent physiological modulators and possible ingredients in functional foods & nutraceuticals

Author keywords

Functional foods; Lignans; Nutraceuticals; Sesame; Sesamin; Sesaminol glucosides; Sesamolin

Indexed keywords

ALIAS; SESAMUM INDICUM;

EID: 79955006445     PISSN: 22127984     EISSN: 18761429     Source Type: Journal    
DOI: 10.2174/2212798411103010017     Document Type: Review
Times cited : (75)

References (119)
  • 1
    • 33947467202 scopus 로고
    • The chemical and physiological properties of sesame oil
    • Budowski P, Markley KS. The chemical and physiological properties of sesame oil. Chem Rev 1951;48(1):125-51.
    • (1951) Chem Rev , vol.48 , Issue.1 , pp. 125-151
    • Budowski, P.1    Markley, K.S.2
  • 2
    • 51649212739 scopus 로고
    • Recent research on sesamin sesamolin + related compounds
    • Budowski P. Recent research on sesamin sesamolin + related compounds. J Am Oil Chem Soc 1964;41(4):280-5.
    • (1964) J Am Oil Chem Soc , vol.41 , Issue.4 , pp. 280-285
    • Budowski, P.1
  • 3
    • 0031031957 scopus 로고    scopus 로고
    • Stereoselective bimolecular phenoxy radical coupling by an auxiliary (dirigent) protein without an active center
    • DOI 10.1126/science.275.5298.362
    • Davin LB, Wang HB, Crowell AL, Bedgar DL, Martin DM, Sarkanen S, et al. Stereoselective bimolecular phenoxy radical coupling by an auxiliary (dirigent) protein without an active center. Science 1997;275(5298):362-6. (Pubitemid 27051607)
    • (1997) Science , vol.275 , Issue.5298 , pp. 362-366
    • Davin, L.B.1    Wang, H.-B.2    Crowell, A.L.3    Bedgar, D.L.4    Martin, D.M.5    Sarkanen, S.6    Lewis, N.G.7
  • 4
    • 16844377224 scopus 로고    scopus 로고
    • An historical perspective on lignan biosynthesis: Monolignol, allylphenol and hydroxycinnamic acid coupling and downstream metabolism
    • DOI 10.1023/B:PHYT.0000046175.83729.b5
    • Davin LB, Lewis NG. An historical perspective on lignan biosynthesis: Monolignol, allylphenol and hydroxycinnamic acid coupling and downstream metabolism. Phytochem Rev 2003;2(3):257-88. (Pubitemid 41175231)
    • (2003) Phytochemistry Reviews , vol.2 , Issue.3 , pp. 257-288
    • Davin, L.B.1    Lewis, N.G.2
  • 5
    • 0032575882 scopus 로고    scopus 로고
    • Furanofuran lignan metabolism as a function of seed maturation in Sesamum indicum: Methylenedioxy bridge formation
    • Jiao Y, Davin LB, Lewis NG. Furanofuran lignan metabolism as a function of seed maturation in Sesamum indicum: Methylenedioxy bridge formation. Phytochem 1998;49(2):387-94.
    • (1998) Phytochem , vol.49 , Issue.2 , pp. 387-394
    • Jiao, Y.1    Davin, L.B.2    Lewis, N.G.3
  • 6
    • 0032008228 scopus 로고    scopus 로고
    • Biosynthesis of antioxidant lignans in Sesamum indicum seeds
    • DOI 10.1016/S0031-9422(97)00727-9, PII S0031942297007279
    • Kato, M. J. Chu, A. Davin, L. B. Lewis, N. G. Biosynthesis of antioxidant lignans in Sesamum indicum seeds. Phytochem 1998;47(4):583-91. (Pubitemid 28051422)
    • (1998) Phytochemistry , vol.47 , Issue.4 , pp. 583-591
    • Kato, M.J.1    Chu, A.2    Davin, L.B.3    Lewis, N.G.4
  • 7
    • 0030712153 scopus 로고    scopus 로고
    • (+)-Episesaminone, a Sesamum indicum furofuran lignan. Isolation and hemisynthesis
    • DOI 10.1021/np9702953
    • Marchand PA, Kato MJ, Lewis NG. (+)-episesaminone, a Sesamum indicum furofuran lignan. Isolation and hemisynthesis. J Nat Prod 1997;60(11):1189-92. (Pubitemid 27516221)
    • (1997) Journal of Natural Products , vol.60 , Issue.11 , pp. 1189-1192
    • Marchand, P.A.1    Kato, M.J.2    Lewis, N.G.3
  • 8
    • 0031150042 scopus 로고    scopus 로고
    • Oxygen insertion in Sesamum indicum furanofuran lignans. Diastereoselective syntheses of enzyme substrate analogues
    • Marchand PA, Zajicek J, Lewis NG. Oxygen insertion in Sesamum indicum furanofuran lignans. Diastereoselective syntheses of enzyme substrate analogues. Can J Chem 1997;75(6):840-9. (Pubitemid 127498054)
    • (1997) Canadian Journal of Chemistry , vol.75 , Issue.6 , pp. 840-849
    • Marchand, P.A.1    Zajicek, J.2    Lewis, N.G.3
  • 9
    • 33947472815 scopus 로고
    • Isolation and structure of sesangolin, a constituent of sesamum angolense (Welw.)
    • Jones WA, Becker ED, Beroza, M. Isolation and structure of sesangolin, a constituent of sesamum angolense (Welw.). J Org Chem 1962;27(9):3232-5.
    • (1962) J Org Chem , vol.27 , Issue.9 , pp. 3232-3235
    • Jones, W.A.1    Becker, E.D.2    Beroza, M.3
  • 10
    • 44049111509 scopus 로고
    • A furofuran lignan from sesamumalatum
    • Kamaleldin A, Yousif G. A furofuran lignan from sesamumalatum. Phytochem 1992;31(8);2911-2.
    • (1992) Phytochem , vol.31 , Issue.8 , pp. 2911-2912
    • Kamaleldin, A.1    Yousif, G.2
  • 11
    • 0028374674 scopus 로고
    • Variations in the composition of sterols, tocopherols and lignans in seed oils from 4 sesamum species
    • Kamal-Eldin A, Appelqvist LA. Variations in the composition of sterols, tocopherols and lignans in seed oils from 4 sesamum species. J Am Oil Chem Soc 1994;71(2):149-56.
    • (1994) J Am Oil Chem Soc , vol.71 , Issue.2 , pp. 149-156
    • Kamal-Eldin, A.1    Appelqvist, L.A.2
  • 12
  • 13
    • 0000144160 scopus 로고
    • Structure of novel antioxidative lignan glucosides isolated from sesame seed
    • Katsuzaki H, Kawasumi M, Kawakishi S, Osawa T. Structure of novel antioxidative lignan glucosides isolated from sesame seed. Biosci Biotech Biochem 1992;56(12):2087-8.
    • (1992) Biosci Biotech Biochem , vol.56 , Issue.12 , pp. 2087-2088
    • Katsuzaki, H.1    Kawasumi, M.2    Kawakishi, S.3    Osawa, T.4
  • 14
    • 0010760882 scopus 로고
    • Structure of novel antioxidative lignan triglucoside isolated from sesame seed
    • Katsuzaki H, Kawakishi S, Osawa T. Structure of novel antioxidative lignan triglucoside isolated from sesame seed. Heterocycles 1993;36(5):933-6.
    • (1993) Heterocycles , vol.36 , Issue.5 , pp. 933-936
    • Katsuzaki, H.1    Kawakishi, S.2    Osawa, T.3
  • 15
    • 0028372253 scopus 로고
    • Sesaminol glucosides in sesame seeds
    • DOI 10.1016/S0031-9422(00)90603-4
    • Katsuzaki H, Kawakishi S, Osawa T. Sesaminol glucosides in sesame seeds. Phytochem 1994;35(3):773-6. (Pubitemid 2044285)
    • (1994) Phytochemistry , vol.35 , Issue.3 , pp. 773-776
    • Katsuzaki, H.1    Kawakishi, S.2    Osawa, T.3
  • 18
    • 0000915228 scopus 로고
    • Acidic transformation of sesamolin, the sesame-oil constituent, into an antioxidant bisepoxylignan, sesaminol
    • Fukuda Y, Isobe M, Nagata M, Osawa T, Namiki M. Acidic transformation of sesamolin, the sesame-oil constituent, into an antioxidant bisepoxylignan, sesaminol. Heterocycles 1986;24(4):923-6.
    • (1986) Heterocycles , vol.24 , Issue.4 , pp. 923-926
    • Fukuda, Y.1    Isobe, M.2    Nagata, M.3    Osawa, T.4    Namiki, M.5
  • 19
    • 66849140889 scopus 로고    scopus 로고
    • Comparative study of sesame lignans (sesamin, episesamin and sesamolin) affecting gene expression profile and fatty acid oxidation in rat liver
    • Ide T, Lim JS, Odbayar TO, Nakashima Y. Comparative study of sesame lignans (sesamin, episesamin and sesamolin) affecting gene expression profile and fatty acid oxidation in rat liver. J Nutr Sci Vitaminol 2009;55(1):31-43.
    • (2009) J Nutr Sci Vitaminol , vol.55 , Issue.1 , pp. 31-43
    • Ide, T.1    Lim, J.S.2    Odbayar, T.O.3    Nakashima, Y.4
  • 20
    • 84863769963 scopus 로고
    • Sesame in insecticides
    • Eagleson C. Sesame in insecticides. Soap 1942;18:125-7.
    • (1942) Soap , vol.18 , pp. 125-127
    • Eagleson, C.1
  • 22
    • 84863768983 scopus 로고
    • Effect of sesamin and related compounds on the insecticidal action of pyrethrum on the houseflies
    • Haller L, La Forge F, Sullivan WX. Effect of sesamin and related compounds on the insecticidal action of pyrethrum on the houseflies. J Econ Entomol 1942;35:247-8.
    • (1942) J Econ Entomol , vol.35 , pp. 247-248
    • Haller, L.1    La Forge, F.2    Sullivan, W.X.3
  • 23
    • 84863734013 scopus 로고
    • Pyrethrum synergists in sesame oil - Sesamolin, a potent synergist
    • Beroza M. Pyrethrum synergists in sesame oil - sesamolin, a potent synergist. J Am Oil Chem Soc 1954;31(7):302-5.
    • (1954) J Am Oil Chem Soc , vol.31 , Issue.7 , pp. 302-305
    • Beroza, M.1
  • 24
    • 84863771230 scopus 로고
    • Piperonyl butoxide, a new and safe insecticide for the household and field
    • Dove WE. Piperonyl butoxide, a new and safe insecticide for the household and field. Am J Trop Med 1947;27(3):339-45.
    • (1947) Am J Trop Med , vol.27 , Issue.3 , pp. 339-345
    • Dove, W.E.1
  • 25
    • 0344071104 scopus 로고
    • Synergist insecticides
    • Wachs H. Synergist insecticides. Science 1947;15:530-1.
    • (1947) Science , vol.15 , pp. 530-531
    • Wachs, H.1
  • 26
    • 10244278573 scopus 로고
    • Acute toxicity and irritation tests on animals with the new insecticide, piperonyl butoxide
    • Sarles MP, Dove WE, Moore DH. Acute toxicity and irritation tests on animals with the new insecticide, piperonyl butoxide. Am J Trop Med 1949;29(1):151-66.
    • (1949) Am J Trop Med , vol.29 , Issue.1 , pp. 151-166
    • Sarles, M.P.1    Dove, W.E.2    Moore, D.H.3
  • 27
    • 0000237610 scopus 로고
    • Chronic oral toxicity and related studies on animals with the insecticide and pyrethrum synergist, piperonyl butoxide
    • Sarles MP, Vandegrift WB. Chronic oral toxicity and related studies on animals with the insecticide and pyrethrum synergist, piperonyl butoxide. Am J Trop Med Hyg 1952;1(5):862-83.
    • (1952) Am J Trop Med Hyg , vol.1 , Issue.5 , pp. 862-883
    • Sarles, M.P.1    Vandegrift, W.B.2
  • 28
    • 84863729508 scopus 로고
    • Insecticidal synergism with the pyrethrins: Studies on the relationship between chemical structure and synergistic activity in the 3:4- methylenedioxyphenyl compounds
    • Moore BP, Hewlett PS. Insecticidal synergism with the pyrethrins: Studies on the relationship between chemical structure and synergistic activity in the 3:4-methylenedioxyphenyl compounds. J Sci Food Agric 1958;9:666-72.
    • (1958) J Sci Food Agric , vol.9 , pp. 666-672
    • Moore, B.P.1    Hewlett, P.S.2
  • 29
    • 0016238393 scopus 로고
    • Interaction of methylenedioxyphenyl (1, 3-benzodioxole) compounds with enzymes and their effects on mammals
    • Hodgson E, Philpot RM. Interaction of methylenedioxyphenyl (1, 3-benzodioxole) compounds with enzymes and their effects on mammals. Drug Metab Rev 1974;3(2):231-01.
    • (1974) Drug Metab Rev , vol.3 , Issue.2 , pp. 231-201
    • Hodgson, E.1    Philpot, R.M.2
  • 30
    • 0020560388 scopus 로고
    • Induction of cytochrome P-450 by methylenedioxyphenyl compounds: Importance of the methylene carbon
    • Cook JC, Hodgson E. Induction of cytochrome-P-450 by methylenedioxyphenyl compounds - importance of the methylene carbon. Toxicol Appl Pharm 1983;68(1):131-9. (Pubitemid 13128825)
    • (1983) Toxicology and Applied Pharmacology , vol.68 , Issue.1 , pp. 131-139
    • Cook, J.C.1    Hodgson, E.2
  • 31
    • 0021888957 scopus 로고
    • Ligand-complex formation between cytochromes P-450 and P-448 and methylenedioxyphenyl compounds
    • Forge MS, Ionnides C, Parke DV. Ligand-complex formation between cytochrome P450 and P-448 and methylenedioxyphenyl compounds. Xenobiotica 1985;15:333-42. (Pubitemid 15074569)
    • (1985) Xenobiotica , vol.15 , Issue.4 , pp. 333-342
    • Delaforge, M.1    Ioannides, C.2    Parke, D.V.3
  • 32
    • 0014004378 scopus 로고
    • Methylene-C14-dioxy phenyl compounds: Metabolism in relation to their synergistic action
    • Cassida JE, Engel JT, Essac EG, Kamienski FX, Kuwatsuka S. Methylene-C14-dioxy phenyl compounds: Metabolism in relation to their synergistic action. Science 1966;153:1130-3.
    • (1966) Science , vol.153 , pp. 1130-1133
    • Cassida, J.E.1    Engel, J.T.2    Essac, E.G.3    Kamienski, F.X.4    Kuwatsuka, S.5
  • 33
    • 0014853596 scopus 로고
    • Mixed-function oxidase involvement in the biochemistry of insecticide synergists
    • Casida JE. Mixed-function oxidase involvement in the biochemistry of insecticide synergists. J Agric Food Chem 1970;18(5):753-72.
    • (1970) J Agric Food Chem , vol.18 , Issue.5 , pp. 753-772
    • Casida, J.E.1
  • 34
    • 0035977155 scopus 로고    scopus 로고
    • Sesamin, a sesame lignan, decreases fatty acid synthesis in rat liver accompanying the down-regulation of sterol regulatory element binding protein-1
    • DOI 10.1016/S1388-1981(01)00167-6, PII S1388198101001676
    • Ide T, Ashakumary L, Takahashi Y, Kushiro M, Fukuda N, Sugano M. Sesamin, a sesame lignan, decreases fatty acid synthesis in rat liver accompanying the down-regulation of sterol regulatory element binding protein-1. BBA-Mol Cell Biol L 2001;1534(1):1-13. (Pubitemid 34025108)
    • (2001) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol.1534 , Issue.1 , pp. 1-13
    • Ide, T.1    Ashakumary, L.2    Takahashi, Y.3    Kushiro, M.4    Fukuda, N.5    Sugano, M.6
  • 35
    • 15244338731 scopus 로고    scopus 로고
    • Modulating effect of sesamin, a functional lignan in sesame seeds, on the transcription levels of lipid- and alcohol-metabolizing enzymes in rat liver: A DNA microarray study
    • DOI 10.1271/bbb.69.179
    • Tsuruoka N, Kidokoro A, Matsumoto I, Abe K, Kiso Y. Modulating effect of sesamin, a functional lignan in sesame seeds, on the transcription levels of lipid-and alcohol-metabolizing enzymes in rat liver: A DNA microarray study. Biosci Biotechnol Biochem 2005;69(1):179-88. (Pubitemid 40383498)
    • (2005) Bioscience, Biotechnology and Biochemistry , vol.69 , Issue.1 , pp. 179-188
    • Tsuruoka, N.1    Kidokoro, A.2    Matsumoto, I.3    Abe, K.4    Kiso, Y.5
  • 36
    • 67650215671 scopus 로고    scopus 로고
    • Lipid metabolism and nutrigenomics - Impact of sesame lignans on gene expression profiles and fatty acid oxidation in rat liver
    • Ide T, Nakashima Y, Iida H, Yasumoto S, Katsuta M. Lipid metabolism and nutrigenomics - impact of sesame lignans on gene expression profiles and fatty acid oxidation in rat liver. Forum Nutr 2009;61:10-24.
    • (2009) Forum Nutr , vol.61 , pp. 10-24
    • Ide, T.1    Nakashima, Y.2    Iida, H.3    Yasumoto, S.4    Katsuta, M.5
  • 38
    • 0036265056 scopus 로고    scopus 로고
    • Comparative effect of sesamin and episesamin on the activity and gene expression of enzymes in fatty acid oxidation and synthesis in rat liver
    • DOI 10.1016/S0955-2863(01)00224-8, PII S0955286301002248
    • Kushiro M, Masaoka T, Hageshita S, Takahashi Y, Ide T, Sugano M. Comparative effect of sesamin and episesamin on the activity and gene expression of enzymes in fatty acid oxidation and synthesis in rat liver. J Nutr Biochem 2002;13(5):289-95. (Pubitemid 34556690)
    • (2002) Journal of Nutritional Biochemistry , vol.13 , Issue.5 , pp. 289-295
    • Kushiro, M.1    Masaoka, T.2    Hageshita, S.3    Takahashi, Y.4    Ide, T.5    Sugano, M.6
  • 39
    • 1642339580 scopus 로고    scopus 로고
    • Species differences in the physiological activity of dietary lignan (sesamin and episesamin) in affecting hepatic fatty acid metabolism
    • DOI 10.1079/BJN20031067
    • Kushiro M, Takahashi Y, Ide T. Species differences in the physiological activity of dietary lignan (sesamin and episesamin) in affecting hepatic fatty acid metabolism. Br J Nutr 2004;91(3):377-86. (Pubitemid 38386901)
    • (2004) British Journal of Nutrition , vol.91 , Issue.3 , pp. 377-386
    • Kushiro, M.1    Takahashi, Y.2    Ide, T.3
  • 41
    • 0031746585 scopus 로고    scopus 로고
    • The metabolism and n-6/n-3 ratio of essential fatty acids in rats: Effect of dietary arachidonic acid and a mixture of sesame lignans (sesamin and episesamin)
    • DOI 10.1007/s11745-998-0241-7
    • Umeda-Sawada R, Ogawa M, Igarashi O. The metabolism and n-6/n-3 ratio of essential fatty acids in rats: Effect of dietary arachidonic acid and a mixture of sesame lignans (sesamin and episesamin). Lipids 1998;33(6):567-72. (Pubitemid 28283706)
    • (1998) Lipids , vol.33 , Issue.6 , pp. 567-572
    • Umeda-Sawada, R.1    Ogawa, M.2    Igarashi, O.3
  • 43
    • 0025893459 scopus 로고
    • Sesamin is a potent and specific inhibitor of delta-5 desaturase in polyunsaturated fatty-acid biosynthesis
    • Shimizu S, Akimoto K, Shinmen Y, Kawashima H, Sugano M, Yamada H. Sesamin is a potent and specific inhibitor of delta-5 desaturase in polyunsaturated fatty-acid biosynthesis. Lipids 1991;26(7):512-6.
    • (1991) Lipids , vol.26 , Issue.7 , pp. 512-516
    • Shimizu, S.1    Akimoto, K.2    Shinmen, Y.3    Kawashima, H.4    Sugano, M.5    Yamada, H.6
  • 44
    • 0034470073 scopus 로고    scopus 로고
    • Sesamin inhibits lysophosphatidylcholine acyltransferase in Mortierella alpina
    • DOI 10.1042/0300-5127:0280718
    • Chatrattanakunchai S, Fraser T, Stobart K. Sesamin inhibits lysophosphatidylcholine acyltransferase in Mortierella alpina. Biochem Soc Trans 2000;28:718-21. (Pubitemid 32163244)
    • (2000) Biochemical Society Transactions , vol.28 , Issue.6 , pp. 718-721
    • Chatrattanakunchai, S.1    Fraser, T.2    Stobart, K.3
  • 45
    • 0029448672 scopus 로고
    • Interaction of sesamin and eicosapentaenoic acid against Delta 5 desaturation and n-6/n-3 ratio of essential fatty acids in rat
    • Umeda-Sawada R, Takahashi N, Igarashi O. Interaction of sesamin and eicosapentaenoic acid against Delta 5 desaturation and n-6/n-3 ratio of essential fatty acids in rat. Biosci Biotech Biochem 1995;59(12):2268-73.
    • (1995) Biosci Biotech Biochem , vol.59 , Issue.12 , pp. 2268-2273
    • Umeda-Sawada, R.1    Takahashi, N.2    Igarashi, O.3
  • 46
    • 0346158205 scopus 로고    scopus 로고
    • Effects of Sesamin and Capsaicin on the mRNA Expressions of Δ6 and Δ5 Desaturases in Rat Primary Cultured Hepatocytes
    • Umeda-Sawada R, Fujiwara Y, Abe H, Seyama Y. Effects of sesamin and capsaicin on the mRNA expressions of Delta 6 and Delta 5 desaturases in rat primary cultured hepatocytes. J Nutr Sci Vitaminol 2003;49(6):442-6. (Pubitemid 38031349)
    • (2003) Journal of Nutritional Science and Vitaminology , vol.49 , Issue.6 , pp. 442-446
    • Umeda-Sawada, R.1    Fujiwara, Y.2    Abe, H.3    Seyama, Y.4
  • 47
    • 0030870192 scopus 로고    scopus 로고
    • 2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin
    • Chavali SR, Zhong WW, Utsunomiya T, Forse RA. Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. Int Arch Allergy Immunol 1997;114(2):153-60. (Pubitemid 27397070)
    • (1997) International Archives of Allergy and Immunology , vol.114 , Issue.2 , pp. 153-160
    • Chavali, S.R.1    Zhong, W.W.2    Utsunomiya, T.3    Forse, R.A.4
  • 48
    • 0031900287 scopus 로고    scopus 로고
    • Dietary α-linolenic acid increases TNF-α, and decreases IL-6, IL-10 in response to LPS: Effects of sesamin on the Δ-5 desaturation of ω6 and ω3 fatty acids in mice
    • DOI 10.1016/S0952-3278(98)90112-0
    • Chavali SR, Zhong WW, Forse RA. Dietary alpha-linolenic acid increases TNF-alpha, and decreases IL-6, IL-10 in response to LPS: effects of sesamin on the delta-5 desaturation of omega6 and omega3 fatty acids in mice. Prostaglandins Leukot Essent Fatty Acids 1998;58(3):185-91. (Pubitemid 28175106)
    • (1998) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.58 , Issue.3 , pp. 185-191
    • Chavali, S.R.1    Zhong, W.W.2    Forse, R.A.3
  • 49
    • 0033839599 scopus 로고    scopus 로고
    • Effects of sesamin-supplemented dietary fat emulsions on the ex vivo production of lipopolysaccharide-induced prostanoids and tumor necrosis factor α in rats
    • Utsunomiya T, Chavali SR, Zhong WW, Forse RA. Effects of sesamin-supplemented dietary fat emulsions on the ex vivo production of lipopolysaccharide-induced prostanoids and tumor necrosis factor alpha in rats. Am J Clin Nutr 2000;72(3):804-8. (Pubitemid 30667103)
    • (2000) American Journal of Clinical Nutrition , vol.72 , Issue.3 , pp. 804-808
    • Utsunomiya, T.1    Chavali, S.R.2    Zhong, W.W.3    Forse, R.A.4
  • 50
    • 0029439535 scopus 로고
    • Effects of sesamin and alpha-tocopherol, individually or in combination, on the polyunsaturated fatty acid metabolism, chemical mediator production, and immunoglobulin levels in Sprague-Dawley rats
    • Gu JY, Wakizono Y, Tsujita A, Lim BO, Nonaka M, Yamada K, et al. Effects of sesamin and alpha-tocopherol, individually or in combination, on the polyunsaturated fatty acid metabolism, chemical mediator production, and immunoglobulin levels in Sprague-Dawley rats. Biosci Biotechnol Biochem 1995;59(12):2198-202.
    • (1995) Biosci Biotechnol Biochem , vol.59 , Issue.12 , pp. 2198-2202
    • Gu, J.Y.1    Wakizono, Y.2    Tsujita, A.3    Lim, B.O.4    Nonaka, M.5    Yamada, K.6
  • 52
  • 53
    • 85006153466 scopus 로고
    • Effect of sesamin on cholesterol-synthesis and on the distribution of incorporated linoleic-acid in lipid subfractions in cultured rat-cells
    • Umedasawada R, Fujiwara Y, Igarashi O. Effect of sesamin on cholesterol-synthesis and on the distribution of incorporated linoleic-acid in lipid subfractions in cultured rat-cells. Biosci Biotech Biochem 1994;58(11):2114-5.
    • (1994) Biosci Biotech Biochem , vol.58 , Issue.11 , pp. 2114-2115
    • Umedasawada, R.1    Fujiwara, Y.2    Igarashi, O.3
  • 55
    • 0034066998 scopus 로고    scopus 로고
    • Effects of dietary phenolic compounds on tocopherol, cholesterol, and fatty acids in rats
    • Kamal-Eldin A, Frank J, Razdan A, Tengblad S, Basu S, Vessby B. Effects of dietary phenolic compounds on tocopherol, cholesterol, and fatty acids in rats. Lipids 2000;35(4):427-35. (Pubitemid 30252620)
    • (2000) Lipids , vol.35 , Issue.4 , pp. 427-435
    • Kamal-Eldin, A.1    Frank, J.2    Razdan, A.3    Tengblad, S.4    Basu, S.5    Vessby, B.6
  • 56
    • 0029045399 scopus 로고
    • Sesamin (a compound from sesame oil) increases tocopherol levels in rats fed ad-libitum
    • Kamaleldin A, Pettersson D, Appelqvist LA. Sesamin (a compound from sesame oil) increases tocopherol levels in rats fed ad-libitum. Lipids 1995;30(6):499-505.
    • (1995) Lipids , vol.30 , Issue.6 , pp. 499-505
    • Kamaleldin, A.1    Pettersson, D.2    Appelqvist, L.A.3
  • 57
  • 58
    • 23644458309 scopus 로고    scopus 로고
    • Dietary sesame reduces serum cholesterol and enhances antioxidant capacity in hypercholesterolemia
    • DOI 10.1016/j.nutres.2005.05.007, PII S0271531705001107
    • Chen PR, Chien KL, Su TC, Chang CJ, Liu TL, Cheng HC, et al. Dietary sesame reduces serum cholesterol and enhances antioxidant capacity in hypercholesterolemia. Nutr Res 2005;25(6):559-67. (Pubitemid 41133660)
    • (2005) Nutrition Research , vol.25 , Issue.6 , pp. 559-567
    • Chen, P.R.1    Chien, K.L.2    Su, T.C.3    Chang, C.J.4    Liu, T.-L.5    Cheng, H.6    Tsai, C.7
  • 59
    • 33646402584 scopus 로고    scopus 로고
    • Sesame ingestion affects sex hormones, antioxidant status, and blood lipids in postmenopausal women
    • Wu WH, Kang YP, Wang NH, Jou HJ, Wang TA. Sesame ingestion affects sex hormones, antioxidant status, and blood lipids in postmenopausal women. J Nutr 2006;136(5):1270-5.
    • (2006) J Nutr , vol.136 , Issue.5 , pp. 1270-1275
    • Wu, W.H.1    Kang, Y.P.2    Wang, N.H.3    Jou, H.J.4    Wang, T.A.5
  • 60
    • 33845897340 scopus 로고    scopus 로고
    • Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice
    • DOI 10.1007/s00394-006-0617-8
    • Penalvo JL, Hopia A, Adlercreutz H. Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice. Eur J Nutr 2006;45(8):439-44. (Pubitemid 46020594)
    • (2006) European Journal of Nutrition , vol.45 , Issue.8 , pp. 439-444
    • Penalvo, J.L.1    Hopia, A.2    Adlercreutz, H.3
  • 61
    • 38049027893 scopus 로고    scopus 로고
    • Dietary phytosterols inhibit the lipid modulating effects of sesamin in rats
    • Moazzami AA, Frank J, Lundh T, Vessby B, Kamal-Eldin A. Dietary phytosterols inhibit the lipid modulating effects of sesamin in rats. Curr Top Nutr R 2007;5(2-3):93-7.
    • (2007) Curr Top Nutr R , vol.5 , Issue.2-3 , pp. 93-97
    • Moazzami, A.A.1    Frank, J.2    Lundh, T.3    Vessby, B.4    Kamal-Eldin, A.5
  • 63
    • 32044458131 scopus 로고    scopus 로고
    • Sesamin ingestion regulates the transcription levels of hepatic metabolizing enzymes for alcohol and lipids in rats
    • DOI 10.1097/01.alc.0000189296.99704.1f
    • Kiso Y, Tsuruoka N, Kidokoro A, Matsumoto I, Abe K. Sesamin ingestion regulates the transcription levels of hepatic metabolizing enzymes for alcohol and lipids in rats. Alcohol Clin Exp Res 2005;29(11):116s-20s. (Pubitemid 43194337)
    • (2005) Alcoholism: Clinical and Experimental Research , vol.29 , Issue.11 SUPPL.
    • Kiso, Y.1    Tsuruoka, N.2    Kidokoro, A.3    Matsumoto, I.4    Abe, K.5
  • 64
    • 0027059162 scopus 로고
    • Presence of acetylcholine-like substance(s) in Sesamum indicum
    • Gilani AH, Aftab K. Presence of acetylcholine-like substance (s) in Sesamum indicum. Arch Pharm Res 1992;15:95-8. (Pubitemid 23121648)
    • (1992) Archives of Pharmacal Research , vol.15 , Issue.1 , pp. 95-98
    • Gilani, A.H.1    Aftab, K.2
  • 65
    • 0029132039 scopus 로고
    • Antihypertensive effect of sesamin. I. Protection against deoxycorticosterone acetate-salt-induced hypertension and cardiovascular hypertrophy
    • Matsumura Y, Kita S, Morimoto S, Akimoto K, Furuya M, Oka N, et al. Antihypertensive effect of sesamin. I. Protection against deoxycorticosterone acetate-salt-induced hypertension and cardiovascular hypertrophy. Biol Pharm Bull 1995;18(7):1016-9.
    • (1995) Biol Pharm Bull , vol.18 , Issue.7 , pp. 1016-1019
    • Matsumura, Y.1    Kita, S.2    Morimoto, S.3    Akimoto, K.4    Furuya, M.5    Oka, N.6
  • 66
    • 0031808301 scopus 로고    scopus 로고
    • Antihypertensive effect of sesamin. III. Protection against development and maintenance of hypertension in stroke-prone spontaneously hypertensive rats
    • Matsumura Y, Kita S, Tanida Y, Taguchi Y, Morimoto S, Akimoto K, et al. Antihypertensive effect of sesamin. III. Protection against development and maintenance of hypertension in stroke-prone spontaneously hypertensive rats. Biol Pharm Bull 1998;21(5):469-73. (Pubitemid 28259418)
    • (1998) Biological and Pharmaceutical Bulletin , vol.21 , Issue.5 , pp. 469-473
    • Matsumura, Y.1    Kita, S.2    Tanida, Y.3    Taguchi, Y.4    Morimoto, S.5    Akimoto, K.6    Tanaka, T.7
  • 67
    • 0029113025 scopus 로고
    • Antihypertensive effect of sesamin. II. Protection against twokidney, one-clip renal hypertension and cardiovascular hypertrophy
    • Kita S, Matsumura Y, Morimoto S, Akimoto K, Furuya M, Oka N, et al. Antihypertensive effect of sesamin. II. Protection against twokidney, one-clip renal hypertension and cardiovascular hypertrophy. Biol Pharm Bull 1995;18(9):1283-5.
    • (1995) Biol Pharm Bull , vol.18 , Issue.9 , pp. 1283-1285
    • Kita, S.1    Matsumura, Y.2    Morimoto, S.3    Akimoto, K.4    Furuya, M.5    Oka, N.6
  • 68
  • 70
    • 0033774025 scopus 로고    scopus 로고
    • Effects of sesamin on altered vascular reactivity in aortic rings of deoxycorticosterone acetate-salt-induced hypertensive rat
    • Matsumura Y, Kita S, Ohgushi R, Okui T. Effects of sesamin on altered vascular reactivity in aortic rings of deoxycorticosterone acetate-salt-induced hypertensive rat. Biol Pharm Bull 2000;23(9):1041-5.
    • (2000) Biol Pharm Bull , vol.23 , Issue.9 , pp. 1041-1045
    • Matsumura, Y.1    Kita, S.2    Ohgushi, R.3    Okui, T.4
  • 71
    • 10244229076 scopus 로고    scopus 로고
    • Sesamin induces nitric oxide and decreases endothelin-1 production in HUVECs: Possible implications for its antihypertensive effect
    • DOI 10.1097/00004872-200412000-00015
    • Lee CC, Chen PR, Lin S, Tsai SC, Wang BW, Chen WW, et al. Sesamin induces nitric oxide and decreases endothelin-1 production in HUVECs: Possible implications for its anti hypertensive effect. J Hypertens 2004;22(12):2329-38. (Pubitemid 39620283)
    • (2004) Journal of Hypertension , vol.22 , Issue.12 , pp. 2329-2338
    • Lee, C.-C.1    Chen, P.-R.2    Lin, S.3    Tsai, S.-C.4    Wang, B.-W.5    Chen, W.-W.6    Tsai, C.E.7    Shyu, K.-G.8
  • 74
    • 33745272561 scopus 로고    scopus 로고
    • Sesamin metabolites induce an endothelial nitric oxidedependent vasorelaxation through their antioxidative propertyindependent mechanisms: Possible involvement of the metabolites in the antihypertensive effect of sesamin
    • Nakano D, Kwak CJ, Fujii K, Ikemura K, Satake A, Ohkita M, et al. Sesamin metabolites induce an endothelial nitric oxidedependent vasorelaxation through their antioxidative propertyindependent mechanisms: Possible involvement of the metabolites in the antihypertensive effect of sesamin. J Pharmacol Exp Ther 2006;318(1):328-35.
    • (2006) J Pharmacol Exp Ther , vol.318 , Issue.1 , pp. 328-335
    • Nakano, D.1    Kwak, C.J.2    Fujii, K.3    Ikemura, K.4    Satake, A.5    Ohkita, M.6
  • 103
    • 16444374976 scopus 로고    scopus 로고
    • Antioxidative roles of sesamin, a functional lignan in sesame seed, and it's effect on lipid- and alcohol-metabolism in the liver: A DNA microarray study
    • Kiso Y. Antioxidative roles of sesamin, a functional lignan in sesame seed, and it's effect on lipid-and alcohol-metabolism in the liver: a DNA microarray study. Biofactors 2004;21(1-4):191-6. (Pubitemid 40921853)
    • (2004) BioFactors , vol.21 , Issue.1-4 , pp. 191-196
    • Kiso, Y.1
  • 104
    • 34247168396 scopus 로고    scopus 로고
    • Quantitative NMR analysis of a sesamin catechol metabolite in human urine
    • Moazzami AA, Andersson RE, Kamal-Eldin A. Quantitative NMR analysis of a sesamin catechol metabolite in human urine. J Nutr 2007;137(4):940-4. (Pubitemid 46596891)
    • (2007) Journal of Nutrition , vol.137 , Issue.4 , pp. 940-944
    • Moazzami, A.A.1    Andersson, R.E.2    Kamal-Eldin, A.3
  • 106
    • 33645530876 scopus 로고    scopus 로고
    • Sesamin is one of the major precursors of mammalian lignans in sesame seed (Sesamum indicum) as observed in vitro and in rats
    • Liu Z, Saarinen NM, Thompson LU. Sesamin is one of the major precursors of mammalian lignans in sesame seed (Sesamum indicum) as observed in vitro and in rats. J Nutr 2006;136(4):906-12.
    • (2006) J Nutr , vol.136 , Issue.4 , pp. 906-912
    • Liu, Z.1    Saarinen, N.M.2    Thompson, L.U.3
  • 107
    • 54649083249 scopus 로고    scopus 로고
    • Comparison of the induction profile of hepatic drug-metabolizing enzymes between piperonyl butoxide and phenobarbital in rats
    • Watanabe K, Manabe S, Ohashi Y O H, Onodera H K M. Comparison of the induction profile of hepatic drug-metabolizing enzymes between piperonyl butoxide and phenobarbital in rats. J Toxicol Pathol 1998;11(1):1-10.
    • (1998) J Toxicol Pathol , vol.11 , Issue.1 , pp. 1-10
    • Watanabe, K.1    Manabe, S.2    Ohashi, Y.O.H.3    Onodera, H.K.M.4
  • 108
    • 0034597750 scopus 로고    scopus 로고
    • Cytochrome P4503Adependent metabolism of tocopherols and inhibition by sesamin
    • Parker RS, Sontag TJ, Swanson JE. Cytochrome P4503Adependent metabolism of tocopherols and inhibition by sesamin. Biochem Bioph Res Commun 2000;277(3);531-4.
    • (2000) Biochem Bioph Res Commun , vol.277 , Issue.3 , pp. 531-534
    • Parker, R.S.1    Sontag, T.J.2    Swanson, J.E.3
  • 109
    • 0036245234 scopus 로고    scopus 로고
    • Dietary sesame seed and its lignans inhibit 2,7,8-trimethyl-2(2′- carboxyethyl)-6-hydroxychroman excretion into urine of rats fed γ-tocopherol
    • Ikeda S, Tohyama T, Yamashita K. Dietary sesame seed and its lignans inhibit 2, 7, 8-trimethyl-2 (2 '-carboxyethyl)-6-hydroxychroman excretion into urine of rats fed gammatocopherol. J Nutr 2002;132(5):961-6. (Pubitemid 34495445)
    • (2002) Journal of Nutrition , vol.132 , Issue.5 , pp. 961-966
    • Ikeda, S.1    Tohyama, T.2    Yamashita, K.3
  • 110
    • 0037067711 scopus 로고    scopus 로고
    • Cytochrome P450 ω-hydroxylase pathway of tocopherol catabolism: Novel mechanism of regulation of vitamin E status
    • DOI 10.1074/jbc.M201466200
    • Sontag TJ, Parker RS. Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism - Novel mechanism of regulation of vitamin E status. J Biol Chem 2002;277(28):25290-6. (Pubitemid 34951838)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.28 , pp. 25290-25296
    • Sontag, T.J.1    Parker, R.S.2
  • 111
    • 0026749412 scopus 로고
    • Sesame seed lignans and γ-tocopherol act synergistically to produce vitamin E activity in rats
    • Yamashita K, Nohara Y, Katayama K, Namiki M. Sesame seed lignans and gamma-tocopherol act synergistically to produce vitamin-e activity in rats. J Nutr 1992;122(12):2440-6. (Pubitemid 23004643)
    • (1992) Journal of Nutrition , vol.122 , Issue.12 , pp. 2440-2446
    • Yamashita, K.1    Nohara, Y.2    Katayama, K.3    Namiki, M.4
  • 113
  • 114
  • 115
    • 0021809946 scopus 로고
    • Induction of rat-hepatic microsomal cytochrome P-450 and aryl hydrocarbon hydroxylase by 1,3-benzodioxole derivatives
    • Murray M, Wilkinson CF, Dube CE. Induction of rat-hepatic microsomal cytochrome P-450 and aryl hydrocarbon hydroxylase by 1, 3-benzodioxole derivatives. Xenobiotica 1985;15(5):361-8. (Pubitemid 15036872)
    • (1985) Xenobiotica , vol.15 , Issue.5 , pp. 361-368
    • Murray, M.1    Wilkinson, C.F.2    Dube, C.E.3
  • 116
    • 0027264897 scopus 로고
    • Regulation of cytochrome P-450 isozymes by methylenedioxyphenyl compounds
    • DOI 10.1016/0009-2797(93)90101-4
    • Adams NH, Levi PE, Hodgson E. Regulation of cytochrome P-450 isozymes by methylenedioxyphenyl compounds. Chem Biol Interact 1993;86(3):255-74. (Pubitemid 23131892)
    • (1993) Chemico-Biological Interactions , vol.86 , Issue.3 , pp. 255-274
    • Adams, N.H.1    Levi, P.E.2    Hodgson, E.3
  • 117
    • 0033377106 scopus 로고    scopus 로고
    • Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds
    • Nakajima M, Suzuki M, Yamaji R, Takashina H, Shimada N, Yamazaki H, et al. Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds. Xenobiotica 1999;29(12):1191-202. (Pubitemid 30019221)
    • (1999) Xenobiotica , vol.29 , Issue.12 , pp. 1191-1202
    • Nakajima, M.1    Suzuki, M.2    Yamaji, R.3    Takashina, H.4    Shimada, N.5    Yamazaki, H.6    Yokoi, T.7
  • 118
    • 0034232506 scopus 로고    scopus 로고
    • Mechanisms of inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation
    • Murray M. Mechanisms of inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation. Curr Drug Metab 2000;1(1):67-84.
    • (2000) Curr Drug Metab , vol.1 , Issue.1 , pp. 67-84
    • Murray, M.1
  • 119
    • 0343907358 scopus 로고    scopus 로고
    • Effects of piperonyl butoxide and β-naphthoflavone on cytochrome P4501A expression and activity in Atlantic salmon (Salmo salar L.)
    • DOI 10.1897/1551-5028(1997)016<0415:EOPBAN>2.3.CO;2
    • Grosvik BE, Larsen HE, Goksoyr A. Effects of piperonyl butoxide and beta-naphthoflavone on cytochrome P4501A expression and activity in Atlantic salmon (Salmo salar L). Environ Toxicol Chem 1997;16(3):415-23. (Pubitemid 27131641)
    • (1997) Environmental Toxicology and Chemistry , vol.16 , Issue.3 , pp. 415-423
    • Grosvik, B.E.1    Larsen, H.E.2    Goksoyr, A.3


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