Effects of sesamin-supplemented dietary fat emulsions on the ex vivo production of lipopolysaccharide-induced prostanoids and tumor necrosis factor α in rats

American Journal of Clinical Nutrition

Volumn 72, Issue 3, 2000, Pages 804-808

  Utsunomiya, T ^a   Chavali, S R ^a   Zhong, W W ^a   Forse, R A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antiinflammatory effects; Linseed oil; Lipopolysaccharides; Prostaglandins; Prostanoids; Rats; Septic shock; Sesamin; Short term continuous feeding; Tumor necrosis factor

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; ARACHIDONIC ACID; DIHOMO GAMMA LINOLENIC ACID; LINSEED OIL; LIPID EMULSION; LIPOPOLYSACCHARIDE; PROSTAGLANDIN; PROSTAGLANDIN E2; PROSTANOID; SAFFLOWER OIL; SESAMIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; FAT INTAKE; FATTY ACID DESATURATION; LIPID COMPOSITION; MALE; NONHUMAN; PROSTAGLANDIN BLOOD LEVEL; RAT; TUBE FEEDING;

ANIMALIA; CARTHAMUS TINCTORIUS; SESAMUM INDICUM; SIGANUS;

EID: 0033839599     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/72.3.804     Document Type: Article

References (40)

1. Sesamin: A multifunctional gift from nature
2. Contribution of lignan analogues to antioxidative activity of refined unroasted sesame oil
3. 5-desaturation of n-6 fatty acids in mice fed safflower oil diets supplemented with sesamol
4. 2,TxB2 and elevated levels of IL-6 and IL-10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil A saponin
5. 5-desaturation of n-6 and n-3 fatty acids in mice
6. Influence of sesame lignans on various lipid parameters in rats
7. Effects Of sesamin on the fatty acid composition of the liver of rats fed n-6 and n-3 fatty acid-rich diet
8. Cholesterol metabolism in relation to aging and dietary fat in rats and humans
9. Nutritional and pharmacological factors in eicosanoid biology
10. Increased production of TNF-α and decreased levels of dienoic eicosanoids, IL-6 and IL-10 in mice fed menhaden oil and juniper oil diets in response to an intraperitoneal lethal dose of LPS
11. Dietary source of omega-3 fatty acids affects endotoxin-induced peritoneal macrophage tumor necrosis factor and eicosanoid synthesis
12. Effects of dietary lipid manipulation upon inflammatory mediator production by murine macrophages
13. Decreased interleukin-1 beta levels in plasma from rheumatoid arthritis patients after dietary supplementation with n-3 polyunsaturated fatty acids
14. Gamma linolenic acid: An intermediate in essential fatty acid metabolism with potential as an ethical pharmaceutical as a food
15. Omega-3 fatty acids in health and disease and in growth and development
16. 1 treatment of NXB/NZW F1 hybrid mice
17. A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-1pr mice
18. Effects of continuous tube feeding of dietary fat emulsions on eicosanoid production and on fatty acid composition during an acute septic shock in rats
19. A simple method for the isolation and purification of lipids from animal tissues
20. The rapid preparation of fatty acid esters for gas chromatographic analysis
21. Radioimmunoassay for prostaglandins and thromboxanes
22. Immunologic effects of National Cholesterol Education Panel Step-2 diets with and without fish-derived n-3 fatty acid enrichment
23. Dietary supplementation with fish oil enhances in vivo synthesis of tumor necrosis factor
24. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effects of endotoxin
25. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteremia
26. Dietary fat modulation of immune response
27. Essential fatty acids and immune response
28. Effects of manipulation of dietary fatty acids on clinical manifestations of rheumatoid arthritis
29. Suppression of acute and chronic inflammation by orally administered prostaglandins
30. 1 increases survival with extended anhepatic phase during liver transplantation
31. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells
32. Dietary fish oil supplementation in experimental gram-negative infection and in cerebral malaria in mice
33. Alteration of tumor necrosis factor α production by macrophages from mice fed diets high in eicosapentaenoic and docosahexaenoic fatty acids
34. Fatty acid intake and Kupffer cell function: Fish oil alters eicosanoid and monokine production to endotoxin stimulation
35. The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil
36. Cytokine secretion and eicosanoid production in the peripheral blood mononuclear cells of MS patients undergoing dietary supplementation with n-3 polyunsaturated fatty acids
37. Effects of dietary n-6/n-3 polyunsaturated fatty acid balance on tissue lipid levels, fatty acid patterns, and eicosanoid production in rats
38. Lack of dose response by dietary n-3 fatty acids at a constant ratio of n-3 to n-6 fatty acids in suppressing eicosanoid biosynthesis from arachidonic acid
39. Oxygen radical scavengers selectively inhibit interleukin-8 production in human whole blood
40. Antioxidants attenuate endotoxininduced activation of alveolar macrophages