Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug

International Journal of Pharmaceutics

Volumn 409, Issue 1-2, 2011, Pages 289-296

  D'Aurizio, E ^a   Van Nostrum, C F ^b   Van Steenbergen, M J ^b   Sozio, P ^a   Siepmann, F ^c   Siepmann, J ^c   Hennink, W E ^b   Di Stefano, A ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIV LILLE   (France)

Author keywords

Hydrolysis kinetics; l Dopa lipoic acid; Parkinson's disease; PLGA microspheres; Release

Indexed keywords

ANTIPARKINSON AGENT; LEVODOPA; LEVODOPA ALPHA LIPOIC ACID; MICROSPHERE; ORGANIC SOLVENT; POLYGLACTIN; THIOCTIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; DRUG DEGRADATION; DRUG DIFFUSION; DRUG FORMULATION; DRUG HYDROLYSIS; DRUG STABILITY; DRUG SYNTHESIS; DRUG TRANSPORT; EMULSION; ENCAPSULATION; EVAPORATION; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE;

ANTIPARKINSON AGENTS; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; DRUG STABILITY; EMULSIONS; HALF-LIFE; LACTIC ACID; LEVODOPA; MICROSPHERES; PARTICLE SIZE; POLYGLYCOLIC ACID; PRODRUGS; SOLVENTS; THIOCTIC ACID;

EID: 79954990984     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.02.036     Document Type: Article

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