Programmed death-1 is required for systemic self-tolerance in newly generated T cells during the establishment of immune homeostasis

Journal of Autoimmunity

Volumn 36, Issue 3-4, 2011, Pages 301-312

  Thangavelu, G ^a,b   Parkman, J C ^a   Ewen, C L ^b   Uwiera, R R E ^a   Baldwin, T A ^a   Anderson, C C ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Autoimmunity; Co inhibition; PD 1; Thymic selection; Tolerance

Indexed keywords

PROGRAMMED DEATH 1 RECEPTOR; RAG1 PROTEIN; RAG2 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FETUS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HOMEOSTASIS; IMMUNOLOGICAL TOLERANCE; INFLAMMATORY DISEASE; LYMPH NODE; LYMPHOCYTOPENIA; MALE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

ANIMALS; ANTIGENS, SURFACE; APOPTOSIS REGULATORY PROTEINS; AUTOIMMUNITY; FEMALE; HOMEOSTASIS; MALE; MICE; MICE, INBRED C57BL; SELF TOLERANCE; T-LYMPHOCYTES;

EID: 79954847245     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2011.02.009     Document Type: Article

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