Differential requirements of MHC and of DCs for endogenous proliferation of different T-cell subsets in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 48, 2009, Pages 20394-20398

  Do, Jeong Su ^a   Min, Booki ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GLYCOPROTEIN P 15095; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL LINEAGE; CONTROLLED STUDY; DENDRITIC CELL; IN VIVO STUDY; LYMPHOCYTE DEPLETION; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD11C; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DENDRITIC CELLS; FLOW CYTOMETRY; GENES, MHC CLASS II; GENES, T-CELL RECEPTOR BETA; MICE; MICE, KNOCKOUT; T-LYMPHOCYTE SUBSETS;

EID: 73949141119     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0909954106     Document Type: Article

References (31)

1. Kieper WC, et al. (2005) Recent immune status determines the source of antigens that drive homeostatic T cell expansion. J Immunol 174:3158-3163.
2. Min B, Yamane H, Hu-Li J, Paul WE (2005) Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms. J Immunol 174:6039 - 6044.
3. Tan JT, et al. (2001) IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci USA 98:8732-8737.
4. Guimond M, et al. (2009) Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. Nat Immunol 10:149-157.
5. Tan JT, et al. (2002) Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells. J Exp Med 195:1523-1532.
6. Jabbari A, Harty JT (2005) Cutting edge: Differential self-peptide/MHC requirement for maintaining CD8 T cell function versus homeostatic proliferation. J Immunol 175:4829-4833.
7. Martin B, Bourgeois C, Dautigny N, Lucas B (2003) On the role of MHC class II molecules in the survival and lymphopenia-induced proliferation of peripheral CD4+ T cells. Proc Natl Acad Sci USA 100:6021-6026.
8. Min B, Foucras G, Meier-Schellersheim M, Paul WE (2004) Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire. Proc Natl Acad Sci USA 101:3874-3879.
9. Purton JF, et al. (2007) Antiviral CD4+ memory T cells are IL-15 dependent. J Exp Med 204:951-961.
10. Zaft T, Sapoznikov A, Krauthgamer R, Littman DR, Jung S (2005) CD11chigh dendritic cell ablation impairs lymphopenia-driven proliferation of naive and memory CD8+ T cells. J Immunol 175:6428-6435.
11. Gruber A, Brocker T (2005) MHC class I-positive dendritic cells (DC) control CD8 T cell homeostasis in vivo: T cell lymphopenia as a prerequisite for DC-mediated homeostatic proliferation of naive CD8 T cells. J Immunol 175:201-206.
12. DummerW, Ernst B, LeRoy E, Lee D, Surh C (2001) Autologous regulation of naive T cell homeostasis within the T cell compartment. J Immunol 166:2460-2468.
13. Moyron-Quiroz JE, et al. (2006) Persistence and responsiveness of immunologic memory in the absence of secondary lymphoid organs. Immunity 25:643-654.
14. Dai Z, Lakkis FG (2001) Cutting edge: Secondary lymphoid organs are essential for maintaining the CD4, but not CD8, naive T cell pool. J Immunol 167:6711-6715.
15. Ploix C, Lo D, Carson MJ (2001)Aligand for the chemokine receptor CCR7 can influence the homeostatic proliferation of CD4 T cells and progression of autoimmunity. J Immunol 167:6724-6730.
16. Markiewicz MA, et al. (1998) Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules. Proc Natl Acad Sci USA 95:3065-3070.
17. Cho JH, et al. (2007) An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2. J Exp Med 204:1787-1801.
18. Pober JS, Kluger MS, Schechner JS (2001) Human endothelial cell presentation of antigen and the homing of memory/effector T cells to skin. AnnNYAcad Sci 941:12-25.
19. Sapoznikov A, et al. (2007) Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells. J Exp Med 204:1923-1933.
20. Hamel K, et al. (2008) Suppression of proteoglycan-induced arthritis by anti-CD20 B Cell depletion therapy is mediated by reduction in autoantibodies and CD4+ T cell reactivity. J Immunol 180:4994-5003.
21. Do JS, Min B (2009) IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and γδ T cells in vivo. Blood 113:6361-6371.
22. Tyznik AJ, Sun JC, Bevan MJ (2004) The CD8 population in CD4-deficient mice is heavily contaminated with MHC class II-restricted T cells. J Exp Med 199:559-565.
23. Rist M, Smith C, Bell MJ, Burrows SR, Khanna R (2009) Cross-recognition of HLA DR4 alloantigen by virus-specific CD8+ T cells: A new paradigm for self/non-self recognition. Blood 114:2244-2253.
24. Hao Y, Legrand N, FreitasAA(2006) The clone size of peripheral CD8 T cells is regulated by TCR promiscuity. J Exp Med 203:1643-1649.
25. Hagen KA, et al. (2004) A role for CD28 in lymphopenia-induced proliferation of CD4 T cells. J Immunol 173:3909-3915.
26. Min B, et al. (2003) Neonates support lymphopenia-induced proliferation. Immunity 18:131-140.
27. Williams DB, Barber BH, Flavell RA, Allen H (1989) Role of beta 2-microglobulin in the intracellular transport and surface expression of murine class I histocompatibility molecules. J Immunol 142:2796-2806.
28. Kaech SM, et al. (2003) Selective expression of the interleukin 7 receptor identifies effectorCD8T cells that give rise to long-livedmemorycells. Nat Immunol 4:1191-1198.
29. Goldrath AW, Luckey CJ, Park R, Benoist C, Mathis D (2004) The molecular program induced in T cells undergoing homeostatic proliferation. Proc Natl Acad Sci USA 101:16885-16890.
30. Hamilton SE, Wolkers MC, Schoenberger SP, Jameson SC (2006) The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells. Nat Immunol 7:475-481.
31. Jung S, et al. (2002) In vivo depletion of CD11c(+) dendritic cells abrogates priming of CD8(+) T cells by exogenous cell-associated antigens. Immunity 17:211-220.