Naphthalene-based RNA editing inhibitor blocks RNA editing activities and editosome assembly in Trypanosoma brucei

Journal of Biological Chemistry

Volumn 286, Issue 16, 2011, Pages 14178-14189

  Moshiri, Houtan ^a,b   Acoca, Stéphane ^a   Kala, Smriti ^b   Najafabadi, Hamed Shateri ^b,c   Hogues, Herve ^d   Purisima, Enrico ^a,d   Salavati, Reza ^a,b,c  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; MAMMALS; NAPHTHALENE; PROTEINS;

ADENYLYLATION; ENDORIBONUCLEASE; LIFE STAGES; MECHANISM OF ACTION; MITOCHONDRIAL GENES; RNA EDITING; TRYPANOSOMA BRUCEI;

RNA;

ADENOSINE TRIPHOSPHATE; EDITOSOME; NAPHTHALENE DERIVATIVE; RIBONUCLEASE; RNA EDITING LIGASE 1; RNA EDITING LIGASE 1 INHIBITOR; RNA EDITING LIGASE 2; RNA LIGASE; UNCLASSIFIED DRUG;

ADENYLATION; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG EFFICACY; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; GENE ACTIVITY; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN RNA BINDING; PROTEIN STRUCTURE; RNA EDITING; TRYPANOSOMA BRUCEI;

MAMMALIA; TRYPANOSOMA BRUCEI; TRYPANOSOMATIDAE;

EID: 79954609543     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.199646     Document Type: Article

References (51)

1. Stuart, K., Brun, R., Croft, S., Fairlamb, A., Gürtler, R. E., McKerrow, J., Reed, S., and Tarleton, R. (2008) J. Clin. Investig. 118, 1301-1310
2. Denise, H., and Barrett, M. P. (2001) Biochem. Pharmacol. 61, 1-5
3. Delespaux, V., and de Koning, H. P. (2007) Drug Resist. Updat. 10, 30-50
4. Simpson, L., Sbicego, S., and Aphasizhev, R. (2003) RNA 9, 265-276
5. Stuart, K. D., Schnaufer, A., Ernst, N. L., and Panigrahi, A. K. (2005) Trends Biochem. Sci. 30, 97-105
6. Kable, M. L., Heidmann, S., and Stuart, K. D. (1997) Trends Biochem. Sci. 22, 162-166
7. Seiwert, S. D., Heidmann, S., and Stuart, K. (1996) Cell 84, 831-841
8. Panigrahi, A. K., Gygi, S. P., Ernst, N. L., Igo, R. P., Jr., Palazzo, S. S., Schnaufer, A., Weston, D. S., Carmean, N., Salavati, R., Aebersold, R., and Stuart, K. D. (2001) Mol. Cell. Biol. 21, 380-389
9. Panigrahi, A. K., Schnaufer, A., Ernst, N. L., Wang, B., Carmean, N., Salavati, R., and Stuart, K. (2003) RNA 9, 484-492
10. Carnes, J., Trotter, J. R., Peltan, A., Fleck, M., and Stuart, K. (2008) Mol. Cell. Biol. 28, 122-130
11. Carnes, J., Trotter, J. R., Ernst, N. L., Steinberg, A., and Stuart, K. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 16614-16619
12. Trotter, J. R., Ernst, N. L., Carnes, J., Panicucci, B., and Stuart, K. (2005) Mol. Cell 20, 403-412
13. Aphasizhev, R., Sbicego, S., Peris, M., Jang, S. H., Aphasizheva, I., Simpson, A. M., Rivlin, A., and Simpson, L. (2002) Cell 108, 637-648
14. Ernst, N. L., Panicucci, B., Igo, R. P., Jr., Panigrahi, A. K., Salavati, R., and Stuart, K. (2003) Mol. Cell 11, 1525-1536
15. Schnaufer, A., Ernst, N. L., Palazzo, S. S., O'Rear, J., Salavati, R., and Stuart, K. (2003) Mol. Cell 12, 307-319
16. Kang, X., Rogers, K., Gao, G., Falick, A. M., Zhou, S., and Simpson, L. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 1017-1022
17. Cruz-Reyes, J., Zhelonkina, A. G., Huang, C. E., and Sollner-Webb, B. (2002) Mol. Cell. Biol. 22, 4652-4660
18. Schnaufer, A., Panigrahi, A. K., Panicucci, B., Igo, R. P., Jr., Wirtz, E., Salavati, R., and Stuart, K. (2001) Science 291, 2159-2162
19. Worthey, E. A., Schnaufer, A., Mian, I. S., Stuart, K., and Salavati, R. (2003) Nucleic Acids Res. 31, 6392-6408
20. Kala, S., and Salavati, R. (2010) RNA 16, 1951-1967
21. Salavati, R., Ernst, N. L., O'Rear, J., Gilliam, T., Tarun, S., Jr., and Stuart, K. (2006) RNA 12, 819-831
22. Guo, X., Ernst, N. L., Carnes, J., and Stuart, K. D. (2010) PLoS One 5, e8913
23. Tarun, S. Z., Jr., Schnaufer, A., Ernst, N. L., Proff, R., Deng, J., Hol, W., and Stuart, K. (2008) RNA 14, 347-358
24. Niemann, M., Brecht, M., Schlüter, E., Weitzel, K., Zacharias, M., and Göringer, H. U. (2008) Nucleic Acids Res. 36, 4465-4473
25. Law, J. A., O'Hearn, S. F., and Sollner-Webb, B. (2008) RNA 14, 1187-1200
26. McManus, M. T., Shimamura, M., Grams, J., and Hajduk, S. L. (2001) RNA 7, 167-175
27. Swift, R. V., Durrant, J., Amaro, R. E., and McCammon, J. A. (2009) Biochemistry 48, 709-719
28. Gao, G., Rogers, K., Li, F., Guo, Q., Osato, D., Zhou, S. X., Falick, A. M., and Simpson, L. (2010) Protist 161, 489-496
29. Amaro, R. E., Schnaufer, A., Interthal, H., Hol, W., Stuart, K. D., and McCammon, J. A. (2008) Proc. Natl. Acad. Sci. U. S. A. 105, 17278-17283
30. Durrant, J. D., Hall, L., Swift, R. V., Landon, M., Schnaufer, A., and Amaro, R. E. (2010) PLoS Negl. Trop. Dis. 4, e803
31. Moshiri, H., and Salavati, R. (2010) Nucleic Acids Res. 38, e138
32. Gordon, J. C., Myers, J. B., Folta, T., Shoja, V., Heath, L. S., and Onufriev, A. (2005) Nucleic Acids Res. 33, W368-W371
33. Irwin, J. J., and Shoichet, B. K. (2005) J. Chem. Inf. Model. 45, 177-182
34. Naïm, M., Bhat, S., Rankin, K. N., Dennis, S., Chowdhury, S. F., Siddiqi, I., Drabik, P., Sulea, T., Bayly, C. I., Jakalian, A., and Purisima, E. O. (2007) J. Chem. Inf. Model. 47, 122-133
35. Cui, Q., Sulea, T., Schrag, J. D., Munger, C., Hung, M. N., Naïm, M., Cygler, M., and Purisima, E. O. (2008) J. Mol. Biol. 379, 787-802
36. Purisima, E. O. (1998) J. Comput. Chem. 19, 1494-1504
37. Purisima, E. O., and Nilar, S. H. (1995) J. Comput. Chem. 16, 681-689
38. Bhat, S., and Purisima, E. O. (2006) Proteins 62, 244-261
39. Allison, J., Rothwell, V., Newport, G., Agabian, N., and Stuart, K. (1984) Nucleic Acids Res. 12, 9051-9066
40. Schneider, A., Charrière, F., Pusnik, M., and Horn, E. K. (2007) Methods Mol. Biol. 372, 67-80
41. Salavati, R., Panigrahi, A. K., Morach, B. A., Palazzo, S. S., Igo, R. P., and Stuart, K. (2002) Mol. Biochem. Parasitol. 120, 23-31
42. Igo, R. P., Jr., Palazzo, S. S., Burgess, M. L., Panigrahi, A. K., and Stuart, K. (2000) Mol. Cell. Biol. 20, 8447-8457
43. Igo, R. P., Jr., Weston, D. S., Ernst, N. L., Panigrahi, A. K., Salavati, R., and Stuart, K. (2002) Eukaryot. Cell 1, 112-118
44. Shaneh, A., and Salavati, R. (2009) J. Mol. Model. 16, 61-76
45. Sabatini, R., and Hajduk, S. L. (1995) J. Biol. Chem. 270, 7233-7240
46. Read, L. K., Göringer, H. U., and Stuart, K. (1994) Mol. Cell. Biol. 14, 2629-2639
47. Aphasizhev, R., Aphasizheva, I., Nelson, R. E., Gao, G., Simpson, A. M., Kang, X., Falick, A. M., Sbicego, S., and Simpson, L. (2003) EMBO J. 22, 913-924
48. Göringer, H. U., Koslowsky, D. J., Morales, T. H., and Stuart, K. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 1776-1780
49. Doherty, A. J., and Suh, S. W. (2000) Nucleic Acids Res. 28, 4051-4058
50. Sbicego, S., Alfonzo, J. D., Estévez, A. M., Rubio, M. A., Kang, X., Turck, C. W., Peris, M., and Simpson, L. (2003) Eukaryot. Cell 2, 560-568
51. Domingo, G. J., Palazzo, S. S., Wang, B., Pannicucci, B., Salavati, R., and Stuart, K. D. (2003) Eukaryot. Cell 2, 569-577