Uridine insertion/deletion RNA editing in trypanosomatids: Specific stimulation in vitro of Leishmania tarentolae REL1 RNA ligase activity by the MP63 zinc finger protein

Protist

Volumn 161, Issue 3, 2010, Pages 489-496

  Gao, Guanghan ^a   Rogers, Kestrel ^b   Li, Feng ^b   Guo, Qiang ^b   Osato, Daren ^b   Zhou, Sharleen X ^c   Falick, Arnold M ^c   Simpson, Larry ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Ligation; Mitochondria; RECC; RNA editing; Trypanosomes

Indexed keywords

LIGASE; MESSENGER RNA; PROTOZOAL PROTEIN; RECOMBINANT PROTEIN; RNA BINDING PROTEIN; URIDINE; ZINC FINGER PROTEIN;

ANIMAL; ARTICLE; BACULOVIRUS; BIOLOGICAL MODEL; CHEMICAL MODEL; ENZYMOLOGY; GENE VECTOR; GENETICS; ISOLATION AND PURIFICATION; LEISHMANIA; METABOLISM; MITOCHONDRION; PROTEIN ANALYSIS; PROTEIN QUATERNARY STRUCTURE; RNA EDITING;

ANIMALS; BACULOVIRIDAE; CARBON-OXYGEN LIGASES; GENETIC VECTORS; LEISHMANIA; MITOCHONDRIA; MODELS, BIOLOGICAL; MODELS, CHEMICAL; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, QUATERNARY; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; RNA EDITING; RNA, MESSENGER; RNA-BINDING PROTEINS; URIDINE; ZINC FINGERS;

HEXAPODA; KINETOPLASTIDA; LEISHMANIA MAJOR; LEISHMANIA TARENTOLAE; TRYPANOSOMA; TRYPANOSOMATIDAE;

EID: 77954864093     PISSN: 14344610     EISSN: 16180941     Source Type: Journal    
DOI: 10.1016/j.protis.2010.01.001     Document Type: Article

References (38)

1. Aphasizhev R, Aphasizheva I, Nelson RE, Gao G, Simpson AM, Kang X, Falick AM, Sbicego S, Simpson L Isolation of a U-insertion/deletion editing complex from Leishmania tarentolae mitochondria. EMBO J 2003, 22:913-924.
2. Avila H, Simpson L Organization and complexity of minicircle-encoded guide RNAs from Trypanosoma cruzi. RNA 1995, 1:939-947.
3. Babbarwal VK, Feck M, Ernst NL, Schnaufer A, Stuart K An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei. RNA 2007, 13:737-744.
4. Blum B, Bakalara N, Simpson L A model for RNA editing in kinetoplastid mitochondria: "Guide" RNA molecules transcribed from maxicircle DNA provide the edited information. Cell 1990, 60:189-198.
5. Carnes J, Trotter JR, Ernst NL, Steinberg A, Stuart K An essential RNase III insertion editing endonuclease in Trypanosoma brucei. Proc Natl Acad Sci USA 2005, 102:16614-16619.
6. Carnes J, Trotter JR, Peltan A, Fleck M, Stuart K RNA editing in Trypanosoma brucei requires three different editosomes. Mol Cell Biol 2008, 28:122-130.
7. Cruz-Reyes J, Rusche LN, Piller KJ, Sollner-Webb B T. brucei RNA editing: adenosine nucleotides inversely affect U-deletion and U-insertion reactions at mRNA cleavage. Mol Cell 1998, 1:401-409.
8. Cruz-Reyes J, Zhelonkina AG, Huang CE, Sollner-Webb B Distinct functions of two RNA ligases in active Trypanosoma brucei RNA editing complexes. Mol Cell Biol 2002, 22:4652-4660.
9. Ernst NL, Panicucci B, Carnes J, Stuart K Differential functions of two editosome exoUases in Trypanosoma brucei. RNA 2009, 15:947-957.
10. Ernst NL, Panicucci B, Igo RP, Panigrahi AK, Salavati R, Stuart K TbMP57 is a 3' terminal uridylyl transferase (TUTase) of the Trypanosoma brucei editosome. Mol Cell 2003, 11:1525-1536.
11. Gao G, Simpson AM, Kang X, Rogers K, Nebohacova M, Li F, Simpson L Functional complementation of Trypanosoma brucei RNA in vitro editing with recombinant RNA ligase. Proc Natl Acad Sci USA 2005, 102:4712-4717.
12. Gao G, Simpson L Is the Trypanosoma brucei REL1 RNA ligase specific for U-deletion RNA editing, and is the REL2 RNA ligase specific for U-insertion editing?. J Biol Chem 2003, 278:27570-27574.
13. Golas MM, Böhm C, Sander B, Effenberger K, Brecht M, Stark H, Göringer HU Snapshots of the RNA editing machine in trypanosomes captured at different assembly stages in vivo. EMBO J 2009, 28:766-778.
14. Guo X, Ernst NL, Stuart KD The KREPA3 zinc finger motifs and OB-fold domain are essential for RNA editing and survival of Trypanosoma brucei. Mol Cell Biol 2008, 28:6939-6953.
15. Kang X, Gao G, Rogers K, Falick AM, Zhou S, Simpson L Reconstitution of full-round uridine-deletion RNA editing with three recombinant proteins. Proc Natl Acad Sci USA 2006, 103:13944-13949.
16. Kang X, Rogers K, Gao G, Falick AM, Zhou S, Simpson L Reconstitution of uridine-deletion precleaved RNA editing with two recombinant enzymes. Proc Natl Acad Sci USA 2005, 102:1017-1022.
17. Kang X, Falick AM, Nelson RE, Gao G, Rogers K, Aphasizhev R, Simpson L Disruption of the zinc finger motifs in the Leishmania tarentolae LC-4 (=TbMP63) L-complex editing protein affects the stability of the L-complex. J Biol Chem 2004, 279:3893-3899.
18. Li F, Ge P, Hu W, Atanasov A, Rogers K, Guo Q, Osato D, Falick AM, Zhou H, Simpson L Structure of the core editing complex (L-complex) involved in uridine insertion/deletion RNA editing in trypanosomatid mitochondria. Proc Natl Acad Sci USA 2009, 106:12306-12310.
19. Osato D, Rogers K, Guo Q, Li F, Richmond G, Klug F, Simpson L Uridine insertion/deletion RNA editing in trypanosomatid mitochondria: in search of the editosome. RNA 2009, 15:1338-1344.
20. Panigrahi AK, Ogata Y, Zikova A, Anupama A, Dalley RA, Acestor N, Myler PJ, Stuart KD A comprehensive analysis of Trypanosoma brucei mitochondrial proteome. Proteomics 2008, 9:434-450.
21. Peris M, Simpson AM, Grunstein J, Liliental JE, Frech GC, Simpson L Native gel analysis of ribonucleoprotein complexes from a Leishmania tarentolae mitochondrial extract. Mol Biochem Parasitol 1997, 85:9-24.
22. Pollard VW, Hajduk SL Trypanosoma equiperdum minicircles encode three distinct primary transcripts which exhibit guide RNA characteristics. Mol Cell Biol 1991, 11:1668-1675.
23. Puig O, Caspary F, Rigaut G, Rutz B, Bouveret E, Bragado-Nilsson E, Wilm M, Seraphin B The tandem affinity purification (TAP) method: a general procedure of protein complex purification. Methods 2001, 24:218-229.
24. Rogers K, Gao G, Simpson L Uridylate-specific 3' 5'-exoribonucleases involved in uridylate-deletion RNA editing in trypanosomatid mitochondria. J Biol Chem 2007, 282:29073-29080.
25. Salavati R, Ernst NL, O'Rear J, Gilliam T, Tarun S, Stuart K KREPA4, an RNA binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA 2006, 12:819-831.
26. Schnaufer A, Ernst NL, Palazzo SS, O'Rear J, Salavati R, Stuart K Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex. Mol Cell 2003, 12:307-319.
27. Schnaufer A, Wu M, Park YJ, Nakai T, Deng J, Proff R, Hol WG, Stuart KD (2009) A protein-protein interaction map of trypanosome ~20S editosomes. J Biol Chem (published online Dec 14, 2009), doi: 10.1074/jbc.M109.059378.
28. Shu HH, Stuart K A Trypanosoma brucei minicircle encodes the same gRNAs as do minicircles of T. equiperdum ATCC 30019 and T. evansi type-A minicircles. Nucleic Acids Res 1993, 21:2951.
29. Simpson L, Sbicego S, Aphasizhev R Uridine insertion/deletion RNA editing in trypanosome mitochondria: A complex business. RNA 2003, 9:265-276.
30. Simpson L, Aphasizhev R, Gao G, Kang X Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion/deletion RNA editing. RNA 2004, 10:159-170.
31. Simpson L, Aphasizhev R., Lukes J, Cruz-Reyes J Guide to the nomenclature of kinetoplastid RNA editing: A proposal. Protist 2010, 161:2-6.
32. Stuart KD, Schnaufer A, Ernst NL, Panigrahi AK Complex management: RNA editing in trypanosomes. Trends Biochem Sci 2005, 30:97-105.
33. Sturm NR, Simpson L Kinetoplast DNA minicircles encode guide RNAs for editing of cytochrome oxidase subunit III mRNA. Cell 1990, 61:879-884.
34. Sturm NR, Simpson L Partially edited mRNAs for cytochrome b and subunit III of cytochrome oxidase from Leishmania tarentolae mitochondria: RNA editing intermediates. Cell 1990, 61:871-878.
35. Tarun SZ, Schnaufer A, Ernst NL, Proff R, Deng J, Ho W, Stuart K KREPA6 is an RNA-binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA 2008, 14:347-358.
36. Trotter JR, Ernst NL, Carnes J, Panicucci B, Stuart K A deletion site editing endonuclease in Trypanosoma brucei. Mol Cell 2005, 20:403-412.
37. Wang B, Ernst NL, Palazzo SS, Panigrahi AK, Salavati R, Stuart K TbMP44 is essential for RNA editing and structural integrity of the editosome in Trypanosoma brucei. Eukaryot Cell 2003, 2:578-587.
38. Yasuhira S, Simpson L Minicircle-encoded guide RNAs from Crithidia fasciculata RNA 1995, 1:634-643.