p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival

Cell Research

Volumn 21, Issue 4, 2011, Pages 666-682

  Croft, Daniel R ^a   Crighton, Diane ^a   Samuel, Michael S ^a   Lourenco, Filipe C ^a   Munro, June ^a   Wood, Jenifer ^a   Bensaad, Karim ^a,b   Vousden, Karen H ^a   Sansom, Owen J ^a   Ryan, Kevin M ^a   Olson, Michael F ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

actin; cofilin; cytoskeleton; DNA damage; LIMK; p53; RhoC

Indexed keywords

ACTIN; ANTINEOPLASTIC AGENT; LIM KINASE; LIMK2 PROTEIN, HUMAN; PROTEIN P53; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; RHOC PROTEIN, HUMAN; RND3 PROTEIN, HUMAN; ROCK1 PROTEIN, HUMAN; ROCK2 PROTEIN, HUMAN; SMALL INTERFERING RNA; TP53 PROTEIN, HUMAN;

ANIMAL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CYTOSKELETON; DNA DAMAGE; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; IMMUNOBLOTTING; METABOLISM; MICROARRAY ANALYSIS; MOUSE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ACTINS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CYTOSKELETON; DNA DAMAGE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOBLOTTING; LIM KINASES; MICE; MICROARRAY ANALYSIS; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79954417023     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2010.154     Document Type: Article

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