Lead finding for acetyl cholinesterase inhibitors from natural origin: Structure activity relationship and scope

Mini-Reviews in Medicinal Chemistry

Volumn 11, Issue 3, 2011, Pages 247-262

  Mukherjee, P K ^a   Satheeshkumar, N ^a   Venkatesh, P ^a   Venkatesh, M ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

Acetylcholinesterase inhibitors; Alzheimer's; Ethnomedical; Structure activity relationship

Indexed keywords

ALKALOID DERIVATIVE; AMARYLLIDACEAE ALKALOID; CHOLINESTERASE INHIBITOR; DITERPENOID; FLAVANONE DERIVATIVE; GALANTAMINE; GLYCOSIDE; INDOLE ALKALOID; ISOQUINOLINE ALKALOID; LEAD; LYCOPODIUM ALKALOID DERIVATIVE; MEROTERPENOID; MONOTERPENOID; NATURAL PRODUCT; PHYSOSTIGMINE; PLANT EXTRACT; PREGNANE ALKALOID DERIVATIVE; PREGNANE DERIVATIVE; PREGNANE GLYCOSIDE; PROTOPINE; STEROIDAL ALKALOID DERIVATIVE; STEROL DERIVATIVE; STILBENE DERIVATIVE; TERPENE DERIVATIVE; TERPENOID DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG; UNINDEXED DRUG; WITHANOLIDE; XANTHONE DERIVATIVE; ZEATIN;

ALZHEIMER DISEASE; DRUG ACTIVITY; DRUG BINDING; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG POTENTIATION; ENZYME INHIBITION; GASTROINTESTINAL SYMPTOM; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LYCOPODIUM; MEDICINAL PLANT; NONHUMAN; PHYTOCHEMISTRY; REVIEW; STRUCTURE ACTIVITY RELATION; TRADITIONAL MEDICINE;

ACETYLCHOLINESTERASE; ALKALOIDS; CHOLINESTERASE INHIBITORS; GLYCOSIDES; HETEROCYCLIC COMPOUNDS; HUMANS; NERVOUS SYSTEM DISEASES; STEROLS; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TERPENES;

EID: 79953779864     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955711795049880     Document Type: Review

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