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Bioorganic and Medicinal Chemistry

Volumn 12, Issue 9, 2004, Pages 1995-2003

Kinetics and structure-activity relationship studies on pregnane-type steroidal alkaloids that inhibit cholinesterases

(6) Khalid, Asaad a Zaheer ul Haq, a Anjum, Shazia a Khan, M Riaz a Atta ur Rahman, a Choudhary, M Iqbal a

a UNIVERSITY OF KARACHI (Pakistan)

Author keywords

Acetylcholinesterase; Butyrylcholinesterase; Inhibition; Kinetic studies; SAR; Sarcococca saligna; Steroidal alkaloids

Indexed keywords

2 HYDROXYSALIGNAMINE; 2 HYDROXYSALIGNARINE E; 2BETA HYDROXYEPIPACHYSAMINE D; 5,6 DEHYDROSARCONIDINE; ACETYLCHOLINESTERASE; ALKALOID DERIVATIVE; AXILLARIDINE A; AXILLARINE C; AXILLARINE F; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; DICTYOPHLEBINE; EPIPACHYSAMINE; ISO N FORMYLCHONEFORMINE; PREGNANE DERIVATIVE; SALIGCINNAMIDE; SALIGNAMINE; SALIGNENAMIDE; SALIGNENAMIDE C; SALIGNENAMIDE D; SALIGNENAMIDE E; SALIGNENAMIDE F; SARCODININE; SARCORINE; SARSALIGNENONE; SARSALIGNONE; UNCLASSIFIED DRUG; VAGANINE;

ARTICLE; CHOLINESTERASE INHIBITION; DRUG ISOLATION; DRUG PROTEIN BINDING; ENZYME INHIBITOR COMPLEX; HYDROPHOBICITY; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; ALKALOIDS; BUTYRYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; KINETICS; MODELS, MOLECULAR; PREGNANES; STRUCTURE-ACTIVITY RELATIONSHIP;

SARCOCOCCA; SARCOCOCCA SALIGNA;

EID: 1842686937 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2004.03.002 Document Type: Article

Times cited : (55)

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