Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 Å resolution

FEBS Letters

Volumn 463, Issue 3, 1999, Pages 321-326

  Greenblatt, H M ^a   Kryger, G ^a   Lewis, T ^b   Silman, I ^a   Sussman, J L ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b JEALOTT S HILL RESEARCH STATION   (United Kingdom)

Author keywords

Alzheimer's disease; Cholinesterase; Galanthamine; Herbal medicine; Natural product

Indexed keywords

ACETYLCHOLINESTERASE; DONEPEZIL; GALANTAMINE; RIVASTIGMINE; SABELUZOLE; TACRINE;

ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; CHOLINESTERASE INHIBITION; COMPLEX FORMATION; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN INTERACTION;

ACETYLCHOLINESTERASE; ALZHEIMER DISEASE; ANIMALS; BINDING SITES; CHOLINESTERASE INHIBITORS; DRUG DESIGN; GALANTAMINE; GALANTHUS; HYDROGEN BONDING; MOLECULAR STRUCTURE; STEREOISOMERISM; TORPEDO; X-RAY DIFFRACTION;

GALANTHUS NIVALIS; TORPEDO CALIFORNICA;

EID: 0033408510     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01637-3     Document Type: Article

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