Screening of Indian medicinal plants for acetylcholinesterase inhibitory activity

Phytotherapy Research

Volumn 21, Issue 12, 2007, Pages 1142-1145

  Mukherjee, Pulok K ^a,b   Kumar, Venkatesan ^b   Houghton, Peter J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b JADAVPUR UNIVERSITY   (India)

Author keywords

Acetylcholinesterase; Evalvulus alsinoides; Indian medicinal plants; Microplate assay; Myristica fragrans; Nardostachys jatamansi

Indexed keywords

ACETYLCHOLINESTERASE; ALCOHOL; ANDROGRAPHIS PANICULATA EXTRACT; CENTELLA ASIATICA EXTRACT; EVALVULUS ALSINOIDE EXTRACT; MYRISTICA FRAGRANS EXTRACT; NARDOSTACHYS JATAMANSI EXTRACT; NELUMBO NUCIFERA EXTRACT; PHYSOSTIGMINE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CEREBROVASCULAR ACCIDENT; CONCENTRATION (PARAMETERS); CONVULSION; DRUG INHIBITION; ENZYME ACTIVITY; EPILEPSY; ERYTHROCYTE; HERB; HYSTERIA; IC 50; IN VITRO STUDY; INDIAN; MEDICINAL PLANT; MEDICINE; MENTAL DEFICIENCY; MOUSE; NONHUMAN; RAT; SCREENING;

ANDROGRAPHIS; CENTELLA; CHOLINESTERASE INHIBITORS; CONVOLVULACEAE; INDIA; MYRISTICA FRAGRANS; NARDOSTACHYS; NELUMBO; PLANTS, MEDICINAL;

ANDROGRAPHIS PANICULATA; BOVINAE; CENTELLA ASIATICA; MYRISTICA FRAGRANS; NARDOSTACHYS JATAMANSI; NELUMBO NUCIFERA;

EID: 37849032383     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2224     Document Type: Article

References (36)

1. Anonymous. 1992. The Wealth of India Vol. 3. Council for Scientific and Industrial Research: New Delhi.
2. Apparao MVR, Srinivasan K, Rao K. 1973. Effect of Mandookaparni (Centella asiatica) on the general mental ability (Medhya) of mentally retarded children. J Res Indian Med 8: 9-16.
3. Bores GM, Huger FP, Petko W et al. 1996. Pharmacological evaluation of novel Alzheimer's disease therapeutics, acetylcholinesterase inhibitors related to galanthamine. J Pharmacol Exp Ther 227: 728-738.
4. Chen Y, Han T, Qin L, Rui Y, Zheng H. 2003. Effect of total triterpenes from Centella asiatica on the depression behavior and concentration of amino acid in forced swimming mice. Zhong Yao Cai 26: 870-873.
5. Chen SW, Wang WJ, Li WJ et al. 2006. Anxiolytic-like effect of asiaticoside in mice. Pharmacol Biochem Behav 85: 339-344.
6. Dandekar UP, Chandra RS, Dalvi SS et al. 1992. Analysis of a clinically important interaction between phenytoin and Shankhapushpi, an Ayurvedic preparation. J Ethnopharmacol 35: 285-288.
7. Ellman GL, Lourtney DK. Andres V, Gmelin G. 1961. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7: 88-95.
8. Forrest JE, Heacock RA. 1972. Nutmeg and mace, the psychotropic spices from Myristica fragrans. Lloydia 35: 440-449.
9. Green AR, Hainsworth AH, Jackson DM. 2000. GABA potentiation, a logical pharmacological approach for the treatment of acute ischemic stroke. Neuropharmacology 39: 1483-1494.
10. Greig NH, Utsuki T, Yu Q et al. 2001. Butyrylcholinesterase, a new therapeutic target in AD treatment? Alzheimer Insights 7: 1-6.
11. Gupta SS, Seth CB, Mathur VS, Ghooi C, Verma RK. 1994. Central nervous system of some indigenous anti asthmatic drugs. Indian J Physiol Pharmacol 10: 5-14.
12. Gupta YK, Verendra Kumar MH, Srivastava AK. 2003. Effect of Centella asiatica on pentylenetetrazole-induced kindling, cognition and oxidative stress in rats. Pharmacol Biochem Behav 74: 579-585.
13. Johnson N, Davis T, Bosanquet N. 2000. The epidemic of Alzheimer's disease; how can we manage the costs? Pharmacol Econ 18: 215-223.
14. Kelly BD, Gavin BE, Clarke M, Lane A, Larkin C. 2003. Nutmeg and psychosis. Schizophr Res 60: 95-96.
15. Kirtikar KR, Basu BD. 1933. Indian Medicinal Plants. LM Basu: Allahabad.
16. Maiti K, Gantait A, Mukherjee K, Saha BP, Mukherjee PK. 2006. Therapeutic potentials of andrographalide from Andrographis paniculata, a review. J Nat Remedies 6: 1-13.
17. Mandal SC, Dhara A, Maiti BC. 2001. Studies on psychopharmacological activity of Andrographis paniculata extract. Phytother Res 15: 253-256.
18. Mukherjee PK, Kumar V, Mal M, Houghton PJ. 2007a. Acetylcholinesterase inhibitors from plants. Phytomedicine 14: 289-300.
19. Mukherjee PK, Kumar V, Mal M, Houghton PJ. 2007b. In vitro acetylcholinesterase inhibitory activity of essential oil and its main constituents of Acorus calamus. Planta Med 73: 283-285.
20. Mukherjee PK, Saha K, Balasubramanian R, Pal M, Saha BP. 1996. Studies on psychopharmacological effects of Nelumbo nucifera Gaertn. rhizome extract. J Ethnopharmacol 54: 63-67.
21. Murthy KRS. 1998. Bhavaprakasa of Bhavamisra. Krishnadas Academy: Varanasi.
22. Nalini K, Arroor AR, Karanth KS, Rao. 1992. Effect of Centella asiatica fresh leaf aqueous extract on learning and memory and biogenic amine turnover in albino rats. Fitoterapia 3: 232-237.
23. Nordberg A, Svensson AL. 1998. Cholinesterase inhibitors in the treatment of Alzheimer's disease, a comparison of tolerability and pharmacology. Drug Safety 19: 465-480.
24. Park CH, Kim SH, Choi W et al. 1996. Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa. Planta Med 62: 405-409.
25. Parle M, Dhingra D, Kulkarni SK. 2004. Improvement of mouse memory by Myristica fragrans seeds. J Med Food 7: 157-161.
26. Perry EK. 1986. The cholinergic hypothesis, ten years on. Br Med Bull 42: 63-69.
27. Prabhu VM, Karanth KS, Rao A, Vidya PM, Sudhakar K. 1994. Effect of Nardostachys jatamansi on biogenic amines and inhibitory amino acids in the rat brain. Planta Med 60: 114-117.
28. Rao SB, Chetana M, Uma Devi P. 2005. Centella asiatica treatment during postnatal period enhances learning and memory in mice. Physiol Behav 86: 449-457.
29. Ren Y, Houghton PJ, Hider RCH. 2006. Relevant activities of extracts and constituents of animals used in traditional Chinese medicine for central nervous system effects associated with Alzheimer's disease. J Pharm Pharmacol 58: 989-996.
30. Sakina MR, Dandiya PC. 1990. A psycho-neuropharmacological profile of Centella asiatica extract. Fitoterapia 4: 291-296.
31. Salim S, Ahmad M, Zafar KS, Ahmad AS, Islam F. 2003. Protective effect of Nardostachys jatamansi in rat cerebral ischemia. Pharmacol Biochem Behav 74: 481-486.
32. Siripurapu KB, Gupta P, Bhatia G, Maurya R, Nath C, Palit G. 2005. Adaptogenic and anti-amnesic properties of Evolvulus alsinoides in rodents. Pharmacol Biochem Behav 81: 424-432.
33. Sonavane GS, Sarveiya VP, Kasture VS, Kasture SB. 2002. Anxiogenic activity of Myristica fragrans seeds. Pharmacol Biochem Behav 71: 247-252.
34. Soumyanath A, Zhong YP, Gold SA et al. 2005. Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in vitro. J Pharm Pharmacol 57: 1221-1229.
35. Vaidyaratnam PSV. 1994. In Indian Medicinal Plants, A Compendium of 500 Species, vol. 2. Orient Longman: Madras, 52.
36. Veerendra Kumar MH, Gupta YK. 2002. Effect of different extracts of Centella asiatica on cognition and oxidative stress markers in rats. J Ethnopharmacol 79: 253-260.