New cholinesterase inhibiting steroidal alkaloids from the leaves of Sarcococca coriacea of Nepalese origin

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 11, 2002, Pages 1423-1426

  Kalauni, Surya K ^a   Choudhary, Muhammad Iqbal ^b   Khalid, Asaad ^b   Manandhar, Mangala Devi ^a   Shaheen, Farzana ^b   Atta ur Rahman, ^b   Gewali, Mohan Bikram ^a  

^a TRIBHUVAN UNIVERSITY   (Nepal)

^b UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

Acetylcholinesterase; Butyrylcholinesterase; Buxaceae; Sarcococca coriacea; Steroidal alkaloid

Indexed keywords

ACETIC ACID DERIVATIVE; ALKALOID; CHOLINESTERASE; EPOXYSARCOVAGENINE; FUNTUMAFRINE; N METHYLFUNTUMINE; PLANT EXTRACT; SARCOCOCA CORIACEA EXTRACT; UNCLASSIFIED DRUG; CHOLINESTERASE INHIBITOR; STEROID;

ARTICLE; CHOLINESTERASE INHIBITION; CONCENTRATION (PARAMETERS); ENZYME ACTIVITY; ENZYME BLOOD LEVEL; NEPAL; NONHUMAN; PLANT LEAF; SARCOCOCCA CORIACEA; SPECTROSCOPY; STRUCTURE ANALYSIS; BUXACEAE; CHEMISTRY; ISOLATION AND PURIFICATION;

ALKALOIDS; BUXACEAE; CHOLINESTERASE INHIBITORS; NEPAL; PLANT EXTRACTS; PLANT LEAVES; STEROIDS;

EID: 0036833310     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.1423     Document Type: Article

References (27)

1. Taylor P., Neurology, 51, S30-35, (1998).
2. Yu Q. S., Holloway H. W., Utsuki T., Brossi A., Greig N. H., J. Med. Chem., 42, 1855-1861 (1999).
3. Qiu M., Nie R., Li Z., Yunnan Zhiwu Yanjiu, 16, 286-300 (1994)
4. [Chem. Abstr., 122, 101602r (1995)].
5. Atta-ur-Rahman, Anjum S., Farooq A., Khan M. R., Parveen Z., Choudhary M. I., J. Nat. Prod., 61, 202-206 (1998).
6. Kiamuddin M., Hye H. K. M. A., Pak. J. Sci. Ind. Res., 13, 59-62 (1970).
7. Hara H., Chater A. O., Williams L. H. J., "An Enumeration of the Flowering Plants of Nepal," Vol. 3, A Joint Project of British Museum (Natural History) London and University of Tokyo, Trustees of British Museum (Natural History), Mansell Book Binders Limited: London, U. K., 1982, p. 200.
8. Pavia D. L., Lampman G. M., Kriz G. S., "Introduction to Spectroscopy," second edition, Harcourt Brace College Publishers, U.S.A., 1996.
9. Atta-ur-Rahman, Anjum S., Farooq A., Khan M. R., Choudhary M. I., Nat. Prod. Lett., 11, 297-304 (1998).
10. Chiu M., Nie R., Li Z., Zhou J., J. Nat. Prod., 55, 25-28 (1992).
11. Zou Z.-M., Li L.-J., Yang M., Yu S.-S., Cong P.-Z., Yu D.-Q., Phytochemistry, 46, 1091-1093 (1997).
12. Janot M. M., Qui K. H., Goutarel R., Compt. Rend., 250, 2445-2447 (1960).
13. Kohli J. M., Zaman A., Kidwai A. R., Phytochemistry, 10, 442-445 (1971).
14. Qie M., Nie R., Zhou J., Yunnan Zhiwu Yanjiu, 13, 445-451 (1991)
15. [Chem Abstr., 117, 108079f (1992)].
16. Atta-ur-Rahman, Choudhary M. I., Khan M. R., Iqbal M. Z., Nat. Prod. Lett., 11, 81-91 (1998).
17. Dadoun H., Conreur C., Cave A., Phytochemistry, 12, 923-928, (1973).
18. Jayasinghe U. L. B., Nadeem M., Atta-ur-Rahman, Choudhary M. I., Ratnayake H. D., Amtul Z., Nat. Prod. Lett., 12, 103-109 (1998).
19. Naeem I., Khan N., Choudhary M. I., Atta-ur-Rahman, Phytochemistry, 43, 903-906 (1996).
20. Atta-ur-Rahman, Khan M. R., Choudhary M. I., Iqbal M. Z., Phytochemistry, 45, 861-864 (1997).
21. Mann J., "Secondary Metabolites," Oxford University Press, Oxford, 1978, p. 155.
22. Ellman G. L., Courtney D., Andres V., Featherston R. M., Biochem. Pharmacol., 7, 88-95 (1961).
23. Atta-ur-Rahman, Parveen S., Khalid A., Farooq A., Ayattollahi S. A. M., Choudhary M. I., Heterocycles, 49, 481-488 (1999).
24. Sussman J. L., Harel M., Frolow F., Oefner C., Goldman A., Toker L., Silman I., Science, 253, 8872-8879 (1991).
25. Bon S., Vigny M., Massoulie J., Proc. Natl. Acad. Sci., U.S.A., 76, 2546-2550 (1979).
26. Chatonnet A., Lockridge O., Biochem. J., 260, 625-634 (1989).
27. Manske R. H. F. J., "The Alkaloids," Vol. 9, Chapter 8, Academic Press, New York, 1960, p. 419.