The effects of an amino acid supplement on glucose homeostasis, inflammatory markers, and incretins after laparoscopic gastric bypass

Journal of the American College of Surgeons

Volumn 212, Issue 4, 2011, Pages 617-625

  Breitman, Igal ^a   Saraf, Neha ^b   Kakade, Manasi ^b   Yellumahanthi, Kishore ^b   White, Merritt ^b   Hackett, Jo Ann ^b   Clements, Ronald H ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; C PEPTIDE; C REACTIVE PROTEIN; GASTRIC INHIBITORY POLYPEPTIDE; GHRELIN; GLUCOSE; GLUTAMINE; INCRETIN; INSULIN; INTERLEUKIN 6; LEPTIN; LEUCINE; SOMATOMEDIN;

ADULT; ARTICLE; BODY MASS; BODY WEIGHT; CLINICAL ARTICLE; FEMALE; GLUCOSE HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; LAPAROSCOPIC GASTRIC BYPASS; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; STOMACH BYPASS; WEIGHT REDUCTION;

ADULT; ARGININE; BLOOD GLUCOSE; C-REACTIVE PROTEIN; DIETARY SUPPLEMENTS; FEMALE; GASTRIC BYPASS; GLUTAMINE; HUMANS; INCRETINS; INTERLEUKIN-6; LAPAROSCOPY; MALE; MIDDLE AGED; OBESITY, MORBID; PILOT PROJECTS; TREATMENT OUTCOME; VALERATES;

EID: 79953772897     PISSN: 10727515     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2010.12.040     Document Type: Article

References (47)

1. Allied Health Sciences Section Ad Hoc Nutrition Committee. ASMBS allied health nutritional guidelines for the surgical weight loss patient. Surg Obes Relat Dis 2008;4:S73-108.
2. Geloneze B, Tambascia MA, Pareja JC, et al. The insulin tolerance test in morbidly obese patients undergoing bariatric surgery. Obes Res 2001;9:763-769. (Pubitemid 33603891)
3. Ballantyne GH, Farkas D, Laker S, et al. Short-term changes in insulin resistance following weight loss surgery for morbid obesity: laparoscopic adjustable gastric banding versus laparoscopic Roux-en-Y gastric bypass. Obes Surg 2006;16:1189-1197. (Pubitemid 44433156)
4. Bastard JP, Maachi M, Lagathu C, et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw 2006;17:4-12.
5. Festa A, d'Agostino Jr R,Williams K, et al. The relation of body fat mass and distribution to markers of chronic inflammation. Int J Obes Relat Metab Disord 2001;25:1407-1415. (Pubitemid 32977855)
6. Permana PA, Menge C, Reaven PD. Macrophage-secreted factors induce adipocyte inflammation and insulin resistance. Biochem Biophys Res Commun 2006;341:507-514. (Pubitemid 43152134)
7. Bikman BT, Zheng D, Pories WJ, et al. Mechanism for improved insulin sensitivity after gastric bypass surgery. J Clin Endocrinol Metab 2008;93:4656-4663.
8. Friedman JE,Dohm GL, Leggett-Frazier N, et al. Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4. J Clin Invest 1992;89:701-705.
9. Ferrannini E,Mingrone G. Impact of different bariatric surgical procedures on insulin action and beta-cell function in type 2 diabetes. Diabetes Care 2009;32:514-520.
10. Lima MM, Pareja JC, Alegre SM, et al. Acute effect of roux-en-y gastric bypass on whole-body insulin sensitivity: a study with the euglycemic- hyperinsulinemic clamp. J Clin Endocrinol Metab 2010;95:3871-3875.
11. Pardina E, Ferrer R, Baena-Fustegueras JA, et al. The relationships between IGF-1 and CRP, NO, leptin, and adiponectin during weight loss in the morbidly obese. Obes Surg 2010;20:623-632.
12. Buchwald H, Estok R, Fahrbach K, et al. Weight and type 2 diabetes after bariatric surgery: systematic review and metaanalysis. Am J Med 2009;122:248-256.e5.
13. Katz A, Nambi SS, Mather K, et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000; 85:2402-2410. (Pubitemid 32269192)
14. Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-419. (Pubitemid 15018832)
15. Morley JJ, Kushner I. Serum C-reactive protein levels. C-Reactive protein and the plasma protein response to tissue injury. Ann N Y Acad Sci 1982;389:406-417.
16. Kamimura D, Ishihara K, Hirano T. IL-6 signal transduction and its physiological roles: the signal orchestration model. Rev Physiol Biochem Pharmacol 2003;149:1-38.
17. Kristiansen OP, Mandrup-Poulsen T. Interleukin-6 and diabetes: the good, the bad, or the indifferent? Diabetes 2005;54:S114-S124.
18. Rattazzi M, Puato M, Faggin E, et al. C-Reactive protein and interleukin-6 in vascular disease: culprits or passive bystanders? J Hypertens 2003;21:1787-1803.
19. Empana JP, Jouven X, Canouï-Poitrine F, et al. C-Reactive protein, interleukin 6, fibrinogen and risk of sudden death in European middle-aged men: the PRIME study. Arterioscler Thromb Vasc Biol 2010;30:2047-2052.
20. Newsholme P, Gaudel C, McClenaghan NH. Nutrient regulation of insulin secretion and beta-cell functional integrity. Adv Exp Med Biol 2010;654:91-114.
21. Linn T, Santosa B, Gronemeyer D, et al. Effect of long-term dietary protein intake on glucose metabolism in humans. Diabetologia 2000;43:1257-1265.
22. Marik PE, Zaloga GP. Immunonutrition in critically ill patients: a systematic review and analysis of the literature. Intensive Care Med 2008;34:1980-1990.
23. Clements RH, Saraf N, Kakade M, et al. Nutritional effect of oral supplement enriched in beta-hydroxy-beta-methylbutyrate, glutamine and arginine on resting metabolic rate after laparoscopic gastric bypass. Surg Endosc 2010 Oct 17.
24. Vázquez LA, Pazos F, Berrazueta JR, et al. Effects of changes in body weight and insulin resistance on inflammation and endothelial function in morbid obesity after bariatric surgery. J Clin Endocrinol Metab 2005;90:316-322. (Pubitemid 40116674)
25. Herrera MF, Pantoja JP, Velázquez-Fernández D, et al. Potential additional effect of omentectomy on metabolic syndrome, acute-phase reactants, and inflammatory mediators in grade III obese patients undergoing laparoscopic Roux-en-Y gastric bypass: a randomized trial. Diabetes Care 2010;33:1413-1418.
26. Salas-Salvadó J, Bulló M, García-Lorda P, et al. Subcutaneous adipose tissue cytokine production is not responsible for the restoration of systemic inflammation markers during weight loss. Int J Obes (Lond) 2006;30:1714-1720. (Pubitemid 44863402)
27. Rubino F, Gagner M, Gentileschi P, et al. The early effect of the Roux-en-Y gastric bypass on hormones involved in body weight regulation and glucose metabolism. Ann Surg 2004;240:236-242. (Pubitemid 38963013)
28. Edén Engström B, Burman P, Holdstock C, et al. Effects of gastric bypass on the GH/IGF-I axis in severe obesity - and a comparison with GH deficiency. Eur J Endocrinol 2006;154:53-59. (Pubitemid 43250736)
29. Krebs M, Krssak M, Bernroider E, et al. Mechanism of amino acid - induced skeletal muscle insulin resistance in humans. Diabetes 2002;51:599-605. (Pubitemid 34760165)
30. Flakoll PJ,Wentzel LS, Rice DE, et al. Short-term regulation of insulin-mediated glucose utilization in four-day fasted human volunteers: role of amino acid availability. Diabetologia 1992;35:357-366.
31. Tremblay F,Marette A. Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells. J Biol Chem 2001;276:38052-38060.
32. Patti ME, Brambilla E, Luzi L, et al. Bidirectional modulation of insulin action by amino acids. J Clin Invest 1998;101:1519-1529. (Pubitemid 28166850)
33. Takano A, Usui I, Haruta T, et al. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin. Mol Cell Biol 2001;21:5050-5062. (Pubitemid 32656402)
34. Tremblay F, Lavigne C, Jacques H, et al. Role of dietary proteins and amino acids in the pathogenesis of insulin resistance. Annu Rev Nutr 2007;27:293-310. (Pubitemid 351373359)
35. Tokunaga C, Yoshino K, Yonezawa K. mTOR integrates amino acid - and energy-sensing pathways. Biochem Biophys Res Commun 2004;313:443-446. (Pubitemid 37543606)
36. Krebs M, Krssak M, Bernroider E, et al. Mechanism of amino acid - induced skeletal muscle insulin resistance in humans. Diabetes 2002;51:599-605. (Pubitemid 34760165)
37. Pisters PW, Restifo NP, Cersosimo E, et al. The effects of euglycemic hyperinsulinemia and amino acid infusion on regional and whole body glucose disposal in man. Metabolism 1991;40:59-65.
38. Linn T, Geyer R, Prassek S, Laube H. Effect of dietary protein intake on insulin secretion and glucose metabolism in insulin-dependent diabetes mellitus. J Clin EndocrinolMetab 1996;81:3938-3943. (Pubitemid 26380399)
39. Abumrad NN, Robinson RP, Gooch BR, et al. The effect of leucine infusion on substrate flux across the human forearm. J Surg Res 1982;32:453-463. (Pubitemid 12124417)
40. Baum JI, O'Connor JC, Seyler JE, et al. Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle. Am J Physiol Endocrinol Metab 2005;288:E86-91.
41. Du M, ShenQW, Zhu MJ, et al. Leucine stimulates mammalian target of rapamycin signaling in C2C12 myoblasts in part through inhibition of adenosine monophosphate-activated protein kinase. J Anim Sci 2007;85:919-927. (Pubitemid 46651831)
42. Yang J, Chi Y, Burkhardt BR, et al. Leucine metabolism in regulation of insulin secretion from pancreatic beta cells. Nutr Rev 2010;68:270-279.
43. Layman DK. The role of leucine in weight loss diets and glucose homeostasis. J Nutr 2003;133:261S-267S.
44. Cota D, Proulx K, Smith KA, et al. Hypothalamic mTOR signaling regulates food intake. Science 2006;312:927-930. (Pubitemid 43727328)
45. Lynch CJ,Gern B, Lloyd C, et al. Leucine in food mediates some of the postprandial rise in plasma leptin concentrations. Am J Physiol Endocrinol Metab 2006;25:25.
46. Roh C, Han J, Tzatsos A, et al. Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes. Am J Physiol Endocrinol Metab 2003;284:E322-330.
47. Kornasio R, Riederer I, Butler-Browne G, et al. Beta-hydroxybeta- methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways. Biochim Biophys Acta 2009;1793:755-763.