Effects of changes in body weight and insulin resistance on inflammation and endothelial function in morbid obesity after bariatric surgery

Journal of Clinical Endocrinology and Metabolism

Volumn 90, Issue 1, 2005, Pages 316-322

  Vázquez, Luis Alberto ^a   Pazos, Fernando ^a,b   Berrazueta, José Ramón ^a   Fernández Escalante, Carlos ^a   García Unzueta, María Teresa ^a   Freijanes, Julio ^a   Amado, José Antonio ^a  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^b Endocrine Unit   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CYCLIC GMP; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIUM DERIVED RELAXING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; PADGEM PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SIALIC ACID; THROMBOMODULIN; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; VON WILLEBRAND FACTOR;

ADULT; ARTICLE; BARIATRIC SURGERY; BODY WEIGHT; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MORBID OBESITY; PRIORITY JOURNAL; WEIGHT REDUCTION;

ADULT; BODY WEIGHT; ENDOTHELIUM; FEMALE; GASTRIC BYPASS; HUMANS; INFLAMMATION; INSULIN RESISTANCE; INTERLEUKIN-6; MALE; MIDDLE AGED; OBESITY, MORBID; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 12244254446     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-032059     Document Type: Article

References (50)

1. DeFronzo RA, Ferrannini E 1991 Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14:173-194
2. Weyer C, Yudkin JS, Stehouwer CD, Schalkwijk CG, Pratley RE, Tataranni PA 2002 Humoral markers of inflammation and endothelial dysfunction in relation to adiposity and in vivo insulin action in Pima Indians. Atherosclerosis 161:233-242
3. Straczkowski M, Lewczuk P, Dzienis-Straczkowska S, Kowalska I, Stepien A, Kinalska I 2002 Elevated soluble intercellular adhesion molecule-1 levels in obesity: relationship to insulin resistance and tumor necrosis factor-α system activity. Metabolism 51:75-78
4. Pinkney JH, Stehouwer CD, Coppack SW, Yudkin JS 1997 Endothelial dysfunction: cause of the insulin resistance syndrome. Diabetes 46(Suppl 2):S9-S23
5. Juhan-Vague I, Thompson SG, Jespersen J 1993 Involvement of the hemostatic system in the insulin resistance syndrome. A study of 1500 patients with angina pectoris. The ECAT Angina Pectoris Study Group. Arterioscler Thromb 13:1865-1873
6. Bagg W, Ferri C, Desideri G, Gamble G, Ockelford P, Braatvedt GD 2001 The influences of obesity and glycemic control on endothelial activation in patients with type 2 diabetes. J Clin Endocrinol Metab 86:5491-5497
7. Cooper R, McFarlane-Anderson N, Bennett FI, Wilks R, Puras A, Tewksbury D, Ward R, Forrester T 1997 ACE, angiotensinogen and obesity: a potential pathway leading to hypertension. J Hum Hypertens 11:107-111
8. Anderson EA, Hoffman RP, Balon TW, Sinkey CA, Mark AL 1991 Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 87:2246-2252
9. Tack CJ, Schefman AE, Willems JL, Thien T, Lutterman JA, Smits P 1996 Direct vasodilator effects of physiological hyperinsulin-aemia in human skeletal muscle. Eur J Clin Invest 26:772-778
10. Arcaro G, Crelti A, Balzano S, Lechi A, Muggeo M, Bonora E, Bonadonna RC 2002 Insulin causes endothelial dysfunction in humans: sites and mechanisms. Circulation 105:576-582
11. Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD 1996 Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 97:2601-2610
12. Feldman RD, Bierbrier GS 1993 Insulin-mediated vasodilation: impairment with increased blood pressure and body mass. Lancet 342:707-709
13. Tchernof A, Nolan A, Sites CK, Ades PA, Poehlman ET 2002 Weight loss reduces C-reactive protein levels in obese postatenopausal women. Circulation 105:564-569
14. Moller DE 2000 Potential role of TNF-α in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol Metab 11:212-217
15. Fernandez-Real JM, Vayreda M, Richart C, Gutierrez C, Broch M, Vendrell J, Ricart W 2001 Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women. J Clin Endocrinol Metab 86:1154-1159
16. Dandona P, Aljada A, Mohanty P, Ghanim H, Hamouda W, Assian E, Ahmad S 2001 Insulin inhibits intranuclear nuclear factor κB and stimulates IκB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 86:3257-3265
17. Davi G, Guagnano MT, Ciabattoni G, Basili S, Falco A, Marinopiccoli M, Nutini M, Sensi S, Patrono C 2002 Platelet activation in obese women: role of inflammation and oxidant stress. JAMA 288:2008-2014
18. Tripathy D, Mohanty P, Dhindsa S, Syed T, Ghanim H, Aljada A, Dandona P 2003 Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects. Diabetes 52:2882-2887
19. Dandona P, Mohanty P, Ghanim H, Aljada A, Browne R, Hamouda W, Prabhala A, Afzal A, Garg R 2001 The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. J Clin Endocrinol Metab 86:355-362
20. Dandona P, Weinstock R, Thusu K, Abdel-Rahrrtan E, Aljada A, Wadden T 1998 Tumor necrosis factor-α in sera of obese patients: fall with weight loss. J Clin Endocrinol Metab 83:2907-2910
21. Laimer M, Ebenbichler CF, Kaser S, Sandhofer A, Weiss H, Nehoda H, Aigner F, Patsch JR 2002 Markers of chronic inflammation and obesity: a prospective study on the reversibility of this association in middle-aged women undergoing weight loss by surgical intervention. Int J Obes Relat Metab Disord 26:659-662
22. Kopp HP, Kopp CW, Festa A, Krzyzanowska K, Kriwanek S, Minar E, Roka R, Schernthaner G 2003 Impact of weight loss on inflammatory proteins and their association with the insulin resistance syndrome in morbidly obese patients. Arterioscler Thromb Vasc Biol 23:1042-1047
23. Mason EE 1987 Morbid obesity: use of vertical banded gastroplasty. Surg Clin North Am 67:521-537
24. Scopinaro N, Adami GF, Marinari GM, Gianetta E, Traverso E, Friedman D, Camerini G, Baschieri G, Simonelli A 1998 Biliopancreatic diversion. World J Surg 22:936-946
25. Poveda JJ, Riestra A, Salas E, Cagigas ML, Lopez-Somoza C, Amado JA, Berrazueta JR 1997 Contribution of nitric oxide to exercise-induced changes in healthy volunteers: effects of acute exercise and long-term physical training. Eur J Clin Invest 27:967-971
26. Steil GM, Volund A, Kahn SE, Bergman RN 1993 Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies. Diabetes 42:250-256
27. Ceballos C, Ribes C, Amado JA, Perez J, Garcia Unzueta MT, de Berrazueta JR 2000 Venous endothelial function in postmenopausal women who are receiving long-term estrogen and progestagen therapy. Fertil Steril 74:268-273
28. Letiexhe MR, Scheen AJ, Gerard PL, Desaive C, Lefebvre PJ 1994 Insulin secretion, clearance and action before and after gastroplasty in severely obese subjects. Int J Obes Relat Metab Disord 18:295-300
29. Vallance P, Collier J, Moncada S 1989 Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo. Cardiovasc Res 23:1053-1057
30. Scherrer U, Randin D, Vollenweider P, Vollenweider L, Nicod P 1994 Nitric oxide release accounts for insulin's vascular effects in humans. J Clin Invest 94:2511-2515
31. Aljada A, Ghanim H, Assian E, Dandona P 2002 Tumor necrosis factor-α inhibits insulin-induced increase in endothelial nitric oxide synthase and reduces insulin receptor content and phosphorylation in human aortic endothelial cells. Metabolism 51:487-491
32. Hwang SJ, Ballantyne CM, Sharrett AR, Smith LC, Davis CE, Gotto Jr AM, Boerwinkle E 1997 Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study. Circulation 96:4219-4225
33. Ziccardi P, Nappo F, Giugliano G, Esposito K, Marfella R, Cioffi M, D'Andrea F, Molinari AM, Giugliano D 2002 Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circulation 19:105:804-809
34. de Lemos JA, Hennekens CH, Ridker PM 2000 Plasma concentration of soluble vascular cell adhesion molecule-1 and subsequent cardiovascular risk. J Am Coll Cardiol 36:423-426
35. Aso Y, Fujiwara Y, Tayama K, Takanashi K, Inukai T, Takemura Y 2001 Relationship between plasma soluble thrombomodulin levels and insulin resistance syndrome in type 2 diabetes: a comparison with von Willebrand factor. Exp Clin Endocrinol Diabetes 109:210-216
36. Anfossi G, Mularoni EM, Burzacca S, Ponziani MC, Massucco P, Mattiello L, Cavalot F, Trovati M 1998 Platelet resistance to nitrates in obesity and obese NIDDM, and normal platelet sensitivity to both insulin and nitrates in lean NIDDM. Diabetes Care 21:121-126
37. Alessi MC, Morange P, Juhan-Vague I 2000 Fat cell function and fibrinolysis. Horm Metab Res 32:504-508
38. Sylvan A, Rutegard JN, Janunger KG, Sjolund B, Nilsson TK 1992 Normal plasminogen activator inhibitor levels at long-term follow-up after jejuno-ileal bypass surgery in morbidly obese individuals. Metabolism 41:1370-1372
39. Sriharan M, Reichelt AJ, Opperman ML, Duncan BB, Mengue SS, Crook MA, Schmidt MI 2002 Total sialic acid and associated elements of the metabolic syndrome in women with and without previous gestational diabetes. Diabetes Care 25:1331-1335
40. Yudkin JS 2003 Adipose tissue, insulin action and vascular disease: inflammatory signals. Int J Obes Relat Metab Disord 27(Suppl 3):S25-S28
41. Aljada A, Mohanty P, Ghanim H, Abdo T, Trípathy D, Chaudhuri A, Dandona P 2004 Increase in intranuclear nuclear factor κB and decrease in inhibitor κB in mononuclear cells after a mixed meal: evidence for a proinflammatory effect. Am J Clin Nutr 79:682-690
42. Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H 2003 Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112: 1821-1830
43. Xydakis AM, Case CC, Jones PH, Hoogeveen RC, Liu MY, Smith EO, Nelson KW, Ballantyne CM 2004 Adiponectin, inflammation, and the expression of the metabolic syndrome in obese individuals: the impact of rapid weight loss through caloric restriction. J Clin Endocrinol Metab 89:2697-2703
44. van Dielen FM, Buurman WA, Hadfoune M, Nijhuis J, Greve JW 2004 Macrophage inhibitory factor, plasminogen activator inhibitor-1, other acute phase proteins, and inflammatory mediators normalize as a result of weight loss in morbidly obese subjects treated with gastric restrictive surgery. J Clin Endocrinol Metab 89:4062-4068
45. Hotamisligil GS, Arner P, Atkinson RL, Spiegelman BM 1997 Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance. Diabetes 46:451-455
46. Gabay C, Kushner I 1999 Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 340:448-454
47. Schauer R 1978 Characterization of sialic acids. Methods Enzymol 50:64-89
48. Duncan BB, Schmidt MI, Pankow JS, Ballantyne CM, Couper D, Vigo A, Hoogeveen R, Folsom AR, Heiss G 2003 Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study. Diabetes 52:1799-1805
49. Fichtischerer S, Rosenberger G, Walter DH, Breuer S, Dimmeler S, Zeiher AM 2000 Elevated C-reactive protein levels and impaired endothelial vasoreactivity in patients with coronary artery disease. Circulation 102:1000-1006
50. Raitakari M, Ilvonen T, Ahotupa M, Lehtimaki T, Harmoinen A, Suominen P, Elo J, Hartiala J, Raitakari OT 2004 Weight reduction with very-low-caloric diet and endothelial function in overweight adults: role of plasma glucose. Arterioscler Thromb Vasc Biol 24:124-128