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0037157760
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(a) Solodenko, W.; Kunz, U.; Kirschning, A. Bioorg. Med. Chem. Lett. 2002, 12, 1833-1835.
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Bioorg. Med. Chem. Lett.
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Solodenko, W.1
Kunz, U.2
Kirschning, A.3
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72
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0041846562
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(b) Kunz, U.; Kirschning, A.; Altwicker, C.; Solodenko, W. J. Chromatogr. A 2003, 1006, 241-249.
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(2003)
J. Chromatogr. A
, vol.1006
, pp. 241-249
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Kunz, U.1
Kirschning, A.2
Altwicker, C.3
Solodenko, W.4
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73
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33749515386
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note
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This aspect is of particular importance when continuous flow processes are envisaged.
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74
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15244358694
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Mayr, M.; Wang, D.; Kröll, R.; Schuler, N.; Prühs, S.; Fürstner, A.; Buchmeiser, M. R. Adv. Synth. Catal. 2005, 347, 484-492.
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(2005)
Adv. Synth. Catal.
, vol.347
, pp. 484-492
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Mayr, M.1
Wang, D.2
Kröll, R.3
Schuler, N.4
Prühs, S.5
Fürstner, A.6
Buchmeiser, M.R.7
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75
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33749510422
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note
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2O, and methanol. Then fresh catalyst 7 was loaded as described above and the "recharged" ring was used in the next cycle of metathesis. This experiment gave the following results: Initial catalyst, loading 3.0 μmol/ring, conversion 99%; 1st recharging, loading 3.0 μmol/ring, conversion 87%; 2nd recharging, loading 3.0 μmol/ring, conversion >99%; 3rd recharging, loading 2.8 μmol/ring, conversion 99%. See the Supporting Information for details.
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76
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33749527840
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note
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For high-throughput experiments described in Table 1 the Radleys 12 Place Heated Carousel Reaction Station (www.radleys.com) was used.
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77
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12344273571
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(a) Michalak, K.; Michalak, M.; Wicha, J. Tetrahedron Lett. 2005, 46, 1149-1153.
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(2005)
Tetrahedron Lett.
, vol.46
, pp. 1149-1153
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Michalak, K.1
Michalak, M.2
Wicha, J.3
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79
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0037239704
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(a) Review: Uma, R.; Crevisy, C.; Gree, R. Chem. Rev. 2003, 103, 27-52.
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(2003)
Chem. Rev.
, vol.103
, pp. 27-52
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Uma, R.1
Crevisy, C.2
Gree, R.3
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82
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0142014454
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(d) Arisawa, M.; Terada, Y.; Nakagawa, M.; Nishida, A. Angew. Chem. 2002, 114, 4926-4928.
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Angew. Chem.
, vol.114
, pp. 4926-4928
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Arisawa, M.1
Terada, Y.2
Nakagawa, M.3
Nishida, A.4
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86
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33749514909
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note
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Interestingly, in the case of 5 immobilized on polyvinyl pyridine, exclusive C-C double bond isomerization instead of CM was observed for this substrate: ref 15.
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88
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1642410821
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(b) Kirschning, A.; Chen, G.-w.; Jaunzems, J.; Jesberger, M.; Kalesse, M.; Lindner, M. Tetrahedron 2004, 60, 3505-3521.
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(2004)
Tetrahedron
, vol.60
, pp. 3505-3521
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Kirschning, A.1
Chen, G.-W.2
Jaunzems, J.3
Jesberger, M.4
Kalesse, M.5
Lindner, M.6
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89
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33749515566
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unpublished results
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The high activity of catalyst 7C has also been confirmed at Solvay GmbH by its application in CM of allylated steroids with α,β-unsaturated partners: Messinger, J.; Schön, U.; Mennecke, K.; Harmrohlf, K.; Kirschning, A. unpublished results.
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Messinger, J.1
Schön, U.2
Mennecke, K.3
Harmrohlf, K.4
Kirschning, A.5
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90
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16244369421
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It has been recently demonstrated that free Ru carbene intermediates in solution can be scavenged by monolithic sol-gel glass-bound styrene ether ligands prior to the onset of competing transition metal decomposition. See Kingsbury, J. S.; Hoveyda, A. H. J. Am. Chem. Soc. 2005, 127, 4510-4517.
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(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 4510-4517
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Kingsbury, J.S.1
Hoveyda, A.H.2
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