Microwave-assisted Dimroth rearrangement of thiazines to dihydropyrimidinethiones: Synthetic and mechanistic aspects

QSAR and Combinatorial Science

Volumn 25, Issue 5-6, 2006, Pages 509-518

  Glasnov, Toma N ^a   Vugts, Danielle J ^b   Koningstein, Manoe M ^b   Desai, Bimbisar ^a   Fabian, Walter M F ^a   Orru, Romano V A ^b   Kappe, C Oliver ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Continuous flow; Density functional theory calculations; Differential scanning calorimetry; Dimroth rearrangement; Heterocycles; Microwave irradiation

Indexed keywords

CALORIMETERS; COMPUTATION THEORY; DENSITY FUNCTIONAL THEORY; DIFFERENTIAL SCANNING CALORIMETRY; IRRADIATION; ORGANIC SOLVENTS; REACTION INTERMEDIATES;

BATCH FLOWS; CONTINUOUS-FLOW; DENSITY-FUNCTIONAL THEORY CALCULATIONS; DIMROTH REARRANGEMENT; HETEROCYCLES; IRRADIATION CONDITIONS; MECHANISTIC ASPECTS; MICROWAVE- IRRADIATIONS; MICROWAVE-ASSISTED; THIONES;

MICROWAVE IRRADIATION;

1 METHYL 2 PYRROLIDINONE; 2 AMINO 1,3 THIAZINE PYRIMIDINE 2 THIONE; 3,4 DIHYDROPYRIMIDINE 2 THIONE DERIVATIVE; AMPHOLYTE; DIHYDROPYRIMIDINETHIONE DERIVATIVE; PYRIMIDINE DERIVATIVE; THIAZINE DERIVATIVE; TOLUENE; UNCLASSIFIED DRUG;

ARTICLE; DENSITY FUNCTIONAL THEORY; DIFFERENTIAL SCANNING CALORIMETRY; MICROWAVE IRRADIATION; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 33745787244     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200540210     Document Type: Article

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