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Volumn 1, Issue 6, 2009, Pages 1103-1118

Biomarkers: Unrealized potential in sports doping analysis

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

EID: 79953317319     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.09.87     Document Type: Review
Times cited : (27)

References (111)
  • 1
    • 44349140555 scopus 로고    scopus 로고
    • Use of doping agents, particularly steroids, in sports and society
    • Sjoqvist F, Garle M, Rane A. Use of doping agents, particularly steroids, in sports and society. Lancet 371(9627), 1872-1882 (2008).
    • (2008) Lancet , vol.371 , Issue.9627 , pp. 1872-1882
    • Sjoqvist, F.1    Garle, M.2    Rane, A.3
  • 2
    • 46949095888 scopus 로고    scopus 로고
    • Medicine and science in the fight against doping in sport
    • Catlin DH, Fitch KD, Ljungqvist A. Medicine and science in the fight against doping in sport. J. Intern. Med. 264, 99-114 (2008).
    • (2008) J. Intern. Med. , vol.264 , pp. 99-114
    • Catlin, D.H.1    Fitch, K.D.2    Ljungqvist, A.3
  • 3
    • 65449121149 scopus 로고    scopus 로고
    • The anti-doping fight from the controller's view - Prevention by means of future oriented analytics
    • Thevis M, Schänzer W. The anti-doping fight from the controller's view - prevention by means of future oriented analytics. Dtsch. Z. Sportmed. 60(3), 66-69 (2009).
    • (2009) Dtsch. Z. Sportmed. , vol.60 , Issue.3 , pp. 66-69
    • Thevis, M.1    Schänzer, W.2
  • 4
    • 42549117285 scopus 로고    scopus 로고
    • Androgenic-anabolic steroids and the Olympic Games
    • Fitch KD. Androgenic-anabolic steroids and the Olympic Games. Asian. J. Androl. 10(3), 384-390 (2008).
    • (2008) Asian. J. Androl. , vol.10 , Issue.3 , pp. 384-390
    • Fitch, K.D.1
  • 5
    • 44349157577 scopus 로고    scopus 로고
    • Pharmacology of anabolic steroids
    • Kicman AT. Pharmacology of anabolic steroids. Br. J. Pharmacol. 154(3), 502-521 (2008).
    • (2008) Br. J. Pharmacol. , vol.154 , Issue.3 , pp. 502-521
    • Kicman, A.T.1
  • 6
    • 13944271511 scopus 로고    scopus 로고
    • Abuse of anabolic androgenic steroids and related substances in sport and exercise
    • Bahrke MS, Yesalis CE. Abuse of anabolic androgenic steroids and related substances in sport and exercise. Pharmacol. 4, 614-620 (2004).
    • (2004) Pharmacol. , vol.4 , pp. 614-620
    • Bahrke, M.S.1    Yesalis, C.E.2
  • 7
    • 69249155397 scopus 로고    scopus 로고
    • Annual banned substance review: The prohibited list 2008 - Analytical approaches in human sports drug testing
    • Thevis M, Kuuranne T, Geyer H, Schanzer W. Annual banned substance review: the prohibited list 2008 - analytical approaches in human sports drug testing. Drug Test. Analysis 1, 4-13 (2009).
    • (2009) Drug Test. Analysis , vol.1 , pp. 4-13
    • Thevis, M.1    Kuuranne, T.2    Geyer, H.3    Schanzer, W.4
  • 8
    • 37649023920 scopus 로고    scopus 로고
    • New drugs and methods of doping and manipulation
    • Thevis M, Kohler M, Schänzer W. New drugs and methods of doping and manipulation. Drug Discov. Today 33(1-2), 59-66 (2008).
    • (2008) Drug Discov. Today , vol.33 , Issue.1-2 , pp. 59-66
    • Thevis, M.1    Kohler, M.2    Schänzer, W.3
  • 9
    • 34249802320 scopus 로고    scopus 로고
    • Emerging drugs - Potential for misuse in sport and doping control detection strategies
    • Thevis M, Schanzer W. Emerging drugs - Potential for misuse in sport and doping control detection strategies. Mini. Rev. Med. Chem. 7(5), 533-539 (2007).
    • (2007) Mini. Rev. Med. Chem. , vol.7 , Issue.5 , pp. 533-539
    • Thevis, M.1    Schanzer, W.2
  • 10
    • 65749089277 scopus 로고    scopus 로고
    • Emerging drugs: Mechanism of action, MS and doping control analysis
    • Thevis M, Thomas A, Kohler M, Beuck S, Schanzer W. Emerging drugs: mechanism of action, MS and doping control analysis. J. Mass. Spectrom. 44(4), 442-460 (2009).
    • (2009) J. Mass. Spectrom. , vol.44 , Issue.4 , pp. 442-460
    • Thevis, M.1    Thomas, A.2    Kohler, M.3    Beuck, S.4    Schanzer, W.5
  • 11
    • 33845980567 scopus 로고    scopus 로고
    • MS in sports drug testing: Structure characterization and analytical assays
    • Thevis M, Schanzer W. MS in sports drug testing: Structure characterization and analytical assays. Mass Spectrom. Rev. 26(1), 79-107 (2007).
    • (2007) Mass Spectrom. Rev. , vol.26 , Issue.1 , pp. 79-107
    • Thevis, M.1    Schanzer, W.2
  • 13
    • 34547645017 scopus 로고    scopus 로고
    • Preventive doping control analysis: Liquid and gas chromatography time-of-flight MS for detection of designer drugs
    • Georgakopolus CG, Vonaparti A, Stamou M et al. Preventive doping control analysis: liquid and gas chromatography time-of-flight MS for detection of designer drugs. Rapid. Commun. Mass. Spectrom. 21(15), 2439-2446 (2007).
    • (2007) Rapid. Commun. Mass. Spectrom. , vol.21 , Issue.15 , pp. 2439-2446
    • Georgakopolus, C.G.1    Vonaparti, A.2    Stamou, M.3
  • 14
    • 37249011308 scopus 로고    scopus 로고
    • Identification and characterization of peptides and proteins in doping control analysis
    • Thevis M, Schanzer W. Identification and characterization of peptides and proteins in doping control analysis. Curr. Proteomics 27(1), 35-50 (2008).
    • (2008) Curr. Proteomics , vol.27 , Issue.1 , pp. 35-50
    • Thevis, M.1    Schanzer, W.2
  • 15
    • 37249011308 scopus 로고    scopus 로고
    • Mass spectrometric determination of insulins and their degradation products in sports drug testing
    • Thevis M, Thoma A, Schanzer W. Mass spectrometric determination of insulins and their degradation products in sports drug testing. Mass Spectrom. Rev. 27(1), 35-50 (2008).
    • (2008) Mass Spectrom. Rev. , vol.27 , Issue.1 , pp. 35-50
    • Thevis, M.1    Thoma, A.2    Schanzer, W.3
  • 16
    • 0037114935 scopus 로고    scopus 로고
    • Detection of isoelectric profiles of erythropoietin in urine: Differentiation of natural and administered recombinant hormones
    • Lasne F, Martin L, Crepin N, de Ceaurriz CJ. Detection of isoelectric profiles of erythropoietin in urine: differentiation of natural and administered recombinant hormones. Anal. Biochem. 311, 119-126 (2002).
    • (2002) Anal. Biochem. , vol.311 , pp. 119-126
    • Lasne, F.1    Martin, L.2    Crepin, N.3    De Ceaurriz, C.J.4
  • 18
    • 44349148405 scopus 로고    scopus 로고
    • Gene doping: The hype and the reality
    • Wells DJ. Gene doping: the hype and the reality. Br. J. Pharmacol. 154, 623-631 (2008).
    • (2008) Br. J. Pharmacol. , vol.154 , pp. 623-631
    • Wells, D.J.1
  • 21
    • 63449125155 scopus 로고    scopus 로고
    • Genetically transformed world records: A reality or in the sphere of fantasy?
    • Gatzidou E, Gatzidou G, Theocharis SE. Genetically transformed world records: a reality or in the sphere of fantasy? Med. Sci. Monit. 15, 41-47 (2009).
    • (2009) Med. Sci. Monit. , vol.15 , pp. 41-47
    • Gatzidou, E.1    Gatzidou, G.2    Theocharis, S.E.3
  • 23
    • 2542544270 scopus 로고    scopus 로고
    • How industry is approaching the search for new diagnostic markers and biomarkers
    • Zolg JW, Langen H. How industry is approaching the search for new diagnostic markers and biomarkers. Mol. Cell Proteomics 3, 345-354 (2004).
    • (2004) Mol. Cell Proteomics , vol.3 , pp. 345-354
    • Zolg, J.W.1    Langen, H.2
  • 26
    • 28544446695 scopus 로고    scopus 로고
    • Biomarkers in Cancer staging, prognosis and treatment selection
    • Ludwig JA, Weinstein JN. Biomarkers in Cancer staging, prognosis and treatment selection. Nat. Rev. Cancer 5, 845-856 (2005).
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 845-856
    • Ludwig, J.A.1    Weinstein, J.N.2
  • 27
    • 33745015014 scopus 로고    scopus 로고
    • Clinical proteomics: New trends for protein microarrays
    • Becker KF, Metzger V, Hipp S, Höfler H. Clinical proteomics: new trends for protein microarrays. Curr. Med. Chem. 13, 1831-1837. (2006).
    • (2006) Curr. Med. Chem. , vol.13 , pp. 1831-1837
    • Becker, K.F.1    Metzger, V.2    Hipp, S.3    Höfler, H.4
  • 28
    • 3342964033 scopus 로고    scopus 로고
    • Biomarker discovery and validation: Technologies and integrative approaches
    • Ilyin SE, Belkowski SM, Plata-Salamán CR. Biomarker discovery and validation: technologies and integrative approaches. Trends Biotechnol. 22, 411-416 (2004).
    • (2004) Trends Biotechnol. , vol.22 , pp. 411-416
    • Ilyin, S.E.1    Belkowski, S.M.2    Plata-Salamán, C.R.3
  • 29
    • 70350077831 scopus 로고    scopus 로고
    • The use of omic technologies for biomarker development to trace functions of anabolic agents
    • DOI: 10.1016/j. chroma. 2009. 01.094 Epub ahead of print
    • Riedmaier I, Becker C, Pfaffl W, Meyer HHD. The use of omic technologies for biomarker development to trace functions of anabolic agents. J. Chrom. A. DOI: 10.1016/j. chroma.2009.01.094 (2009) (Epub ahead of print).
    • (2009) J. Chrom. A.
    • Riedmaier, I.1    Becker, C.2    Pfaffl, W.3    Meyer, H.H.D.4
  • 30
    • 41949127013 scopus 로고    scopus 로고
    • Affinity-based biosensors as promising tools for gene doping detection
    • Minunni M, Scarano S, Mascini M. Affinity-based biosensors as promising tools for gene doping detection. Trends Biotechnol. 26, 236-243 (2008).
    • (2008) Trends Biotechnol. , vol.26 , pp. 236-243
    • Minunni, M.1    Scarano, S.2    Mascini, M.3
  • 31
    • 7244245762 scopus 로고    scopus 로고
    • The International Genome Consortium
    • The International Genome Consortium. Nature 431, 931-945 (2004.).
    • (2004) Nature , vol.431 , pp. 931-945
  • 32
    • 43249099500 scopus 로고    scopus 로고
    • Twenty-five years of quantitative PCR for gene expression analysis
    • VanGuilder HD, Vrana KE, Freeman WM. Twenty-five years of quantitative PCR for gene expression analysis. BioTechniques 44, 619-626 (2008).
    • (2008) BioTechniques , vol.44 , pp. 619-626
    • Vanguilder, H.D.1    Vrana, K.E.2    Freeman, W.M.3
  • 33
    • 38949172372 scopus 로고    scopus 로고
    • Messenger RNA expression profiling using DNA microarray technology: Diagnostic tool, scientific analysis or un-interpretable data?
    • Walker MS, Hughes TA. Messenger RNA expression profiling using DNA microarray technology: diagnostic tool, scientific analysis or un-interpretable data? Int. J. Mol. Med. 21, 13-17 (2008).
    • (2008) Int. J. Mol. Med. , vol.21 , pp. 13-17
    • Walker, M.S.1    Hughes, T.A.2
  • 34
    • 2542568705 scopus 로고    scopus 로고
    • The human plasma proteome. A nonredundant list developed by combination of four separate sources
    • Anderson NL, Polanski M, Pieper R et al. The human plasma proteome. A nonredundant list developed by combination of four separate sources. Mol. Cell Proteomics 3, 311-326 (2004).
    • (2004) Mol. Cell Proteomics , vol.3 , pp. 311-326
    • Anderson, N.L.1    Polanski, M.2    Pieper, R.3
  • 35
    • 39649117755 scopus 로고    scopus 로고
    • The impact of next-generation sequencing technology on genetics
    • Mardis ER. The impact of next-generation sequencing technology on genetics. Trend. Genet. 24, 133-141 (2008).
    • (2008) Trend. Genet. , vol.24 , pp. 133-141
    • Mardis, E.R.1
  • 37
    • 34547872730 scopus 로고    scopus 로고
    • The application of ultra-performance liquid chromatography/tandem MS to the detection and quantitation of apolipoproteins in human serum
    • Kay RG, Gregory B, Grace PB, Pleasance S. The application of ultra-performance liquid chromatography/tandem MS to the detection and quantitation of apolipoproteins in human serum. Rapid. Commun. Mass. Spectrom. 21, 2585-2593 (2007).
    • (2007) Rapid. Commun. Mass. Spectrom. , vol.21 , pp. 2585-2593
    • Kay, R.G.1    Gregory, B.2    Grace, P.B.3    Pleasance, S.4
  • 38
    • 34248523381 scopus 로고    scopus 로고
    • Development of an absolute quantification method targeting growth hormone biomarkers using liquid chromatography coupled to isotope dilution MS
    • Kirsch S, Widart J, Louette J, Focant JF, De Pauw E. Development of an absolute quantification method targeting growth hormone biomarkers using liquid chromatography coupled to isotope dilution MS. J. Chromatogr. A 1153, 300-306 (2007).
    • (2007) J. Chromatogr. A , vol.1153 , pp. 300-306
    • Kirsch, S.1    Widart, J.2    Louette, J.3    Focant, J.F.4    De Pauw, E.5
  • 39
    • 34047209848 scopus 로고    scopus 로고
    • Clinical proteomics: A need to define the field and to begin to set adequate standards
    • Mischak A, Apweiler R, Banks RE. Clinical proteomics: a need to define the field and to begin to set adequate standards. Proteomics Clin. App. 1, 148-156 (2007).
    • (2007) Proteomics Clin. App. , vol.1 , pp. 148-156
    • Mischak, A.1    Apweiler, R.2    Banks, R.E.3
  • 40
    • 33645721632 scopus 로고
    • Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins. Mol. Cell Proteomics 5, 573-588 (2007) 41 O'Farrell PH. High resolution twodimensional electrophoresis of proteins
    • Anderson L, Hunter CL. Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins. Mol. Cell Proteomics 5, 573-588 (2007) 41 O'Farrell PH. High resolution twodimensional electrophoresis of proteins. J. Biol. Chem. 250, 400-421 (1975).
    • (1975) J. Biol. Chem. , vol.250 , pp. 400-421
    • Anderson, L.1    Hunter, C.L.2
  • 41
    • 12444339443 scopus 로고    scopus 로고
    • The human serum proteome: Display of nearly 3700 chromatographically separated protein spots on two dimensional eletrophoresis gels and identification of 325 distinct proteins
    • Pieper R, Gatlin CL, Makusky AJ. The human serum proteome: display of nearly 3700 chromatographically separated protein spots on two dimensional eletrophoresis gels and identification of 325 distinct proteins. Proteomics 3, 1345-1364 (2003).
    • (2003) Proteomics , vol.3 , pp. 1345-1364
    • Pieper, R.1    Gatlin, C.L.2    Makusky, A.J.3
  • 42
    • 0035289178 scopus 로고    scopus 로고
    • Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology
    • Tonge R, Shaw J, Middleton B et al. Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology. Proteomics 1(3), 377-396 (2001).
    • (2001) Proteomics , vol.1 , Issue.3 , pp. 377-396
    • Tonge, R.1    Shaw, J.2    Middleton, B.3
  • 43
    • 33646590920 scopus 로고    scopus 로고
    • Differential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelialmesenchymal transition reveals a migratory/invasive phenotype
    • Keshamouni VG, Michailidis G, Grasso CS et al. Differential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelialmesenchymal transition reveals a migratory/invasive phenotype. J. Proteome Res. 5, 1143-1154 (2006).
    • (2006) J. Proteome Res. , vol.5 , pp. 1143-1154
    • Keshamouni, V.G.1    Michailidis, G.2    Grasso, C.S.3
  • 44
    • 32544459721 scopus 로고    scopus 로고
    • Novel biomarkers of human growth hormone action from serum proteomic profiling using protein chip MS
    • Chung L, Clifford D, Buckley M, Baxter RC. Novel biomarkers of human growth hormone action from serum proteomic profiling using protein chip MS. J. Clin. Endocrinol. Metab. 91(2), 671-677 (2006).
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , Issue.2 , pp. 671-677
    • Chung, L.1    Clifford, D.2    Buckley, M.3    Baxter, R.C.4
  • 45
    • 0025677738 scopus 로고
    • MS of peptides and proteins by matrix-assisted ultraviolet laser desorption/ionization
    • Hillenkamp F, Karas M. MS of peptides and proteins by matrix-assisted ultraviolet laser desorption/ionization. Methods Enzymol. 193, 280-295 (1990).
    • (1990) Methods Enzymol. , vol.193 , pp. 280-295
    • Hillenkamp, F.1    Karas, M.2
  • 46
    • 0001644020 scopus 로고    scopus 로고
    • The human plasma proteome: History, character and diagnostic prospects
    • Anderson NL, Anderson NG. The human plasma proteome: History, character and diagnostic prospects. Mol. Cell. Proteomics 1, 845-867 (2002).
    • (2002) Mol. Cell. Proteomics , vol.1 , pp. 845-867
    • Anderson, N.L.1    Anderson, N.G.2
  • 48
    • 65349115741 scopus 로고    scopus 로고
    • A high confidence, manually validated human blood plasma protein reference set
    • Schenk S, Schoenhals GJ, de Souza G, Mann M. A high confidence, manually validated human blood plasma protein reference set. BMC. Med. Genomics. 1, 41 (2008).
    • (2008) BMC. Med. Genomics. , vol.1 , pp. 41
    • Schenk, S.1    Schoenhals, G.J.2    De Souza, G.3    Mann, M.4
  • 49
    • 54549091125 scopus 로고    scopus 로고
    • Systems biology: Metabonomics
    • Nicholson JK, Lindon JC. Systems biology: Metabonomics. Nature 455, 1054-1056 (2008).
    • (2008) Nature , vol.455 , pp. 1054-1056
    • Nicholson, J.K.1    Lindon, J.C.2
  • 50
    • 32544451155 scopus 로고    scopus 로고
    • Fit-for-purpose method development and validation for successful biomarker measurement
    • Lee JW, Devanarayan V, Barrett YC et al. Fit-for-purpose method development and validation for successful biomarker measurement. Pharm. Res. 23(2), 312-328 (2006).
    • (2006) Pharm. Res. , vol.23 , Issue.2 , pp. 312-328
    • Lee, J.W.1    Devanarayan, V.2    Barrett, Y.C.3
  • 51
    • 34047177929 scopus 로고    scopus 로고
    • Biomarker qualification pilot process at the US Food and Drug Administration
    • Goodsaid F, Frueh F. Biomarker qualification pilot process at the US Food and Drug Administration. AAPS. J. 9(1), E105-E108 (2007).
    • (2007) AAPS. J. , vol.9 , Issue.1
    • Goodsaid, F.1    Frueh, F.2
  • 52
    • 44349094812 scopus 로고    scopus 로고
    • Growth hormone, IGF-I and insulin and their abuse in sport
    • Holt RI, Sönksen PH. Growth hormone, IGF-I and insulin and their abuse in sport. Br. J. Pharmacol. 54(3), 542-556 (2008).
    • (2008) Br. J. Pharmacol. , vol.54 , Issue.3 , pp. 542-556
    • Holt, R.I.1    Sönksen, P.H.2
  • 53
    • 3242704003 scopus 로고    scopus 로고
    • Elite volunteer athletes of different sport disciplines may have elevated baseline GH levels divorced from unaltered levels of both IGF-I and GH-dependent bone and collagen markers: A study on - The-field
    • Sartorio A, Marazzi N, Agosti F et al. Elite volunteer athletes of different sport disciplines may have elevated baseline GH levels divorced from unaltered levels of both IGF-I and GH-dependent bone and collagen markers: a study on-the-field. J. Endocrinol. Invest. 27, 410-415 (2004).
    • (2004) J. Endocrinol. Invest. , vol.27 , pp. 410-415
    • Sartorio, A.1    Marazzi, N.2    Agosti, F.3
  • 55
    • 44349083554 scopus 로고    scopus 로고
    • Regulation of muscle mass by growth hormone and IGF-I
    • Velloso CP. Regulation of muscle mass by growth hormone and IGF-I, Br. J.Pharmacol. 154, 557-568 (2008).
    • (2008) Br. J.Pharmacol. , vol.154 , pp. 557-568
    • Velloso, C.P.1
  • 56
    • 0025999498 scopus 로고
    • Growth hormone heterogeneity: Genes, isohormones, variants, and binding proteins
    • Baumann G. Growth hormone heterogeneity: genes, isohormones, variants, and binding proteins. Endocr. Rev. 12, 424-449 (1991).
    • (1991) Endocr. Rev. , vol.12 , pp. 424-449
    • Baumann, G.1
  • 58
    • 0036217685 scopus 로고    scopus 로고
    • Growth hormone and insulin-like growth factor i in a Sydney Olympic gold medallist
    • Armanini D, Faggian D, Scaroni C, Plebani M. Growth hormone and insulin-like growth factor I in a Sydney Olympic gold medallist. Br. J. Sports Med. 36, 148-149 (2002).
    • (2002) Br. J. Sports Med. , vol.36 , pp. 148-149
    • Armanini, D.1    Faggian, D.2    Scaroni, C.3    Plebani, M.4
  • 61
    • 0029907306 scopus 로고    scopus 로고
    • Growth hormone and the insulin-like growth factor system in myogenesis
    • Florini JR, Ewton DZ, Coolican SA, Growth hormone and the insulin-like growth factor system in myogenesis. Endocr. Rev. 17, 481-517 (1996).
    • (1996) Endocr. Rev. , vol.17 , pp. 481-517
    • Florini, J.R.1    Ewton, D.Z.2    Coolican, S.A.3
  • 62
    • 39749149024 scopus 로고    scopus 로고
    • Quantification of human insulin-like growth factor-1 and qualitative detection of its analogues in plasma using liquid chromatography/electrospray ionisation tandem MS
    • Bredehoft M, Schanzer W, Thevis M. Quantification of human insulin-like growth factor-1 and qualitative detection of its analogues in plasma using liquid chromatography/electrospray ionisation tandem MS. Rapid Commun. Mass Spectrom. 22, 447-485 (2008).
    • (2008) Rapid Commun. Mass Spectrom. , vol.22 , pp. 447-485
    • Bredehoft, M.1    Schanzer, W.2    Thevis, M.3
  • 63
    • 0032416479 scopus 로고    scopus 로고
    • Viral mediated expression of insulin-like growth factor i blocks the aging-related loss of skeletal muscle function
    • Barton-Davis ER, Shoturma DI, Musaro A, Rosenthal N, Sweeney HL. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. Proc. Natl Acad. Sci. USA 95, 15603-15607 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 15603-15607
    • Barton-Davis, E.R.1    Shoturma, D.I.2    Musaro, A.3    Rosenthal, N.4    Sweeney, H.L.5
  • 64
    • 34047092903 scopus 로고    scopus 로고
    • The ABCs of IGF-I isoforms: Impact on muscle hypertrophy and implications for repair
    • Barton ER. The ABCs of IGF-I isoforms: impact on muscle hypertrophy and implications for repair. Appl. Physiol. Nutr. Metab. 31(6), 791-797 (2006).
    • (2006) Appl. Physiol. Nutr. Metab. , vol.31 , Issue.6 , pp. 791-797
    • Barton, E.R.1
  • 66
    • 0036892796 scopus 로고    scopus 로고
    • Ghrelin and growth hormone (GH) secretagogues potentiate GH-releasing hormone (GHRH)-induced cyclic adenosine 3′, 5′-monophosphate production in cells expressing transfected GHRH and GH secretagogue receptors
    • Cunha SR, Mayo KE. Ghrelin and growth hormone (GH) secretagogues potentiate GH-releasing hormone (GHRH)-induced cyclic adenosine 3′, 5′-monophosphate production in cells expressing transfected GHRH and GH secretagogue receptors. Endocrinology 143, 4570-4582 (2002).
    • (2002) Endocrinology , vol.143 , pp. 4570-4582
    • Cunha, S.R.1    Mayo, K.E.2
  • 67
    • 4644338250 scopus 로고    scopus 로고
    • Immune-enhancing effects of growth hormone-releasing hormone delivered by plasmid injection and electroporation
    • Brown PA, Davis WC, Draghia-Akli R. Immune-enhancing effects of growth hormone-releasing hormone delivered by plasmid injection and electroporation. Mol. Ther. 10, 644-651 (2004).
    • (2004) Mol. Ther. , vol.10 , pp. 644-651
    • Brown, P.A.1    Davis, W.C.2    Draghia-Akli, R.3
  • 68
    • 44449122810 scopus 로고    scopus 로고
    • Plasmid growth hormone releasing hormone therapy in healthy and laminitisafflicted horses-evaluation and pilot study
    • Brown PA, Bodles-Brakhop A, Draghia-Akli R. Plasmid growth hormone releasing hormone therapy in healthy and laminitisafflicted horses-evaluation and pilot study. J. Gene. Med. 10, 564-574 (2008).
    • (2008) J. Gene. Med. , vol.10 , pp. 564-574
    • Brown, P.A.1    Bodles-Brakhop, A.2    Draghia-Akli, R.3
  • 69
    • 33644484441 scopus 로고    scopus 로고
    • A new plasmid-mediated approach to supplement somatotropin production in pigs
    • Draghia-Akli R, Fiorotto ML. A new plasmid-mediated approach to supplement somatotropin production in pigs. J. Anim. Sci. 82(E-Suppl.) E264-E269 (2004).
    • (2004) J. Anim. Sci. , vol.82 , Issue.E-SUPPL.
    • Draghia-Akli, R.1    Fiorotto, M.L.2
  • 71
    • 24144492335 scopus 로고    scopus 로고
    • Challenges in detecting the abuse of growth hormone in sport
    • McHugh CM, Park RT, Sönksen PH, Holt RI. Challenges in detecting the abuse of growth hormone in sport. Clin. Chem. 1(9), 1587-1593 (2005).
    • (2005) Clin. Chem. , vol.1 , Issue.9 , pp. 1587-1593
    • McHugh, C.M.1    Park, R.T.2    Sönksen, P.H.3    Holt, R.I.4
  • 73
    • 0030841703 scopus 로고    scopus 로고
    • Serum IGF-I and IGF binding proteins 2 and 3 as potential markers of doping with human GH
    • Kicman AT, Miell JP, Teale JD. Serum IGF-I and IGF binding proteins 2 and 3 as potential markers of doping with human GH. Clin. Endocrinol. 47(1), 43-50 (1997).
    • (1997) Clin. Endocrinol. , vol.47 , Issue.1 , pp. 43-50
    • Kicman, A.T.1    Miell, J.P.2    Teale, J.D.3
  • 74
    • 17744379774 scopus 로고    scopus 로고
    • The effect of four weeks of supraphysiological growth hormone administration on the insulin-like growth factor axis in women and men. GH-2000 Study Group
    • Dall R, Longobardi S, Ehrnborg C. The effect of four weeks of supraphysiological growth hormone administration on the insulin-like growth factor axis in women and men. GH-2000 Study Group. J. Clin. Endocrinol. Metab. 85(11), 4193-4200 (2000).
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , Issue.11 , pp. 4193-4200
    • Dall, R.1    Longobardi, S.2    Ehrnborg, C.3
  • 75
    • 45149093958 scopus 로고    scopus 로고
    • Pharmacodynamics of growth hormone abuse biomarkers and the influence of gender and testosterone: A randomized double-blind placebo-controlled study in young recreational athletes
    • Nelson AE, Meinhardt U, Hansen JL. Pharmacodynamics of growth hormone abuse biomarkers and the influence of gender and testosterone: a randomized double-blind placebo-controlled study in young recreational athletes. J. Clin. Endocrinol. Metab. 93(6), 2213-2222 (2008).
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , Issue.6 , pp. 2213-2222
    • Nelson, A.E.1    Meinhardt, U.2    Hansen, J.L.3
  • 76
    • 33751541145 scopus 로고    scopus 로고
    • Influence of demographic factors and sport type on growth hormone-responsive markers in elite athletes
    • Nelson AE, Howe CJ, Nguyen TV. Influence of demographic factors and sport type on growth hormone-responsive markers in elite athletes. J. Clin. Endocrinol. Metab. 91(11), 4424-4432 (2006).
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , Issue.11 , pp. 4424-4432
    • Nelson, A.E.1    Howe, C.J.2    Nguyen, T.V.3
  • 77
    • 58149154383 scopus 로고    scopus 로고
    • Influence of ethnicity on IGF-I and procollagen III peptide P-III-P in elite athletes and its ability to detect GH abuse. GH-2004 group
    • Erotokritou-Mulligan I, Bassett EE, Cowan DA et al. Influence of ethnicity on IGF-I and procollagen III peptide P-III-P in elite athletes and its ability to detect GH abuse. GH-2004 group. Clin. Endocrinol. 70(1), 161-168 (2009).
    • (2009) Clin. Endocrinol. , vol.70 , Issue.1 , pp. 161-168
    • Erotokritou-Mulligan, I.1    Bassett, E.E.2    Cowan, D.A.3
  • 78
    • 20044365805 scopus 로고    scopus 로고
    • Toward the development of a test for growth hormone (GH) abuse: A study of extreme physiological ranges of GH-dependent markers in 813 elite athletes in the postcompetition setting
    • Healy ML, Dall R, Gibney J et al. Toward the development of a test for growth hormone (GH) abuse: a study of extreme physiological ranges of GH-dependent markers in 813 elite athletes in the postcompetition setting. J. Clin. Endocrinol. Metab. 90, 641-649 (2005).
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 641-649
    • Healy, M.L.1    Dall, R.2    Gibney, J.3
  • 79
    • 47549110008 scopus 로고    scopus 로고
    • The effect of sports injury on insulin-like growth factor-I and type 3 procollagen: Implications for detection of growth hormone abuse in athletes; GH-2004 Group
    • Erotokritou-Mulligan I, Bassett EE, Bartlett C et al. The effect of sports injury on insulin-like growth factor-I and type 3 procollagen: implications for detection of growth hormone abuse in athletes; GH-2004 Group. J. Clin. Endocrinol. Metab. 93(7), 2760-2763 (2008).
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , Issue.7 , pp. 2760-2763
    • Erotokritou-Mulligan, I.1    Bassett, E.E.2    Bartlett, C.3
  • 80
    • 58949086794 scopus 로고    scopus 로고
    • A determination of the pre-analytical storage conditions for insulin like growth factor-I and type III procollagen peptide
    • Holt RIG, Erotokritou-Mulligan I, Ridley SA et al. A determination of the pre-analytical storage conditions for insulin like growth factor-I and type III procollagen peptide. Growth. Horm. IGF Res. 19(1), 43-50 (2009).
    • (2009) Growth. Horm. IGF Res. , vol.19 , Issue.1 , pp. 43-50
    • Rig, H.1    Erotokritou-Mulligan, I.2    Ridley, S.A.3
  • 81
    • 48949094590 scopus 로고    scopus 로고
    • Within-subject variability and analytic imprecision of insulin like growth factor axis and collagen markers: Implications for clinical diagnosis and doping tests
    • Nguyen TV, Nelson AE, Howe CJ et al. Within-subject variability and analytic imprecision of insulin like growth factor axis and collagen markers: implications for clinical diagnosis and doping tests. Clin. Chem. 54(8), 1265-1267 (2008).
    • (2008) Clin. Chem. , vol.54 , Issue.8 , pp. 1265-1267
    • Nguyen, T.V.1    Nelson, A.E.2    Howe, C.J.3
  • 82
    • 42549168155 scopus 로고    scopus 로고
    • A robust test for growth hormone doping - Present status and future prospects
    • Nelson AE, Ho KK. A robust test for growth hormone doping - present status and future prospects. Asian J. Androl. 10(3), 416-425 (2008).
    • (2008) Asian J. Androl. , vol.10 , Issue.3 , pp. 416-425
    • Nelson, A.E.1    Ho, K.K.2
  • 83
    • 52249105352 scopus 로고    scopus 로고
    • Circulating nucleic acids in the assessment of endogenous growth hormone production
    • Thakkar R, Butt H, Powrie AN, Holt J, Swaminathan R. Circulating nucleic acids in the assessment of endogenous growth hormone production. Ann. NY Acad. Sci. 1137, 58-65 (2008).
    • (2008) Ann. NY Acad. Sci. , vol.1137 , pp. 58-65
    • Thakkar, R.1    Butt, H.2    Powrie, A.N.3    Holt, J.4    Swaminathan, R.5
  • 84
    • 35748973599 scopus 로고    scopus 로고
    • Identification of candidate genes and expression profiles, as doping biomarkers
    • Paparini A, Impagnatiello F, Pistilli A et al. Identification of candidate genes and expression profiles, as doping biomarkers. Ann. Ig. 19(4), 303-314 (2007).
    • (2007) Ann. Ig. , vol.19 , Issue.4 , pp. 303-314
    • Paparini, A.1    Impagnatiello, F.2    Pistilli, A.3
  • 85
    • 70350233334 scopus 로고    scopus 로고
    • A proteomic approach combining mass spectrometric and bioinformatics analysis for the detection and identification of biomarkers to recombinant human growth hormone administration in humans
    • Boateng J, Kay R, Lancashire L et al. A proteomic approach combining mass spectrometric and bioinformatics analysis for the detection and identification of biomarkers to recombinant human growth hormone administration in humans. Proteomics. Clin. Appl. 3, 912-922 (2009).
    • (2009) Proteomics. Clin. Appl. , vol.3 , pp. 912-922
    • Boateng, J.1    Kay, R.2    Lancashire, L.3
  • 86
    • 60149098957 scopus 로고    scopus 로고
    • The use of proteomic and bioinformatics techniques for the detection of protein biomarkers following growth hormone administration
    • Boateng J, Lancashire L, Brown P et al. The use of proteomic and bioinformatics techniques for the detection of protein biomarkers following growth hormone administration. Internet J. Genom. Proteom. 2(2), 912-922 (2007).
    • (2007) Internet J. Genom. Proteom. , vol.2 , Issue.2 , pp. 912-922
    • Boateng, J.1    Lancashire, L.2    Brown, P.3
  • 87
    • 67649201758 scopus 로고    scopus 로고
    • Multiplexed LC-MS/MS analysis of horse plasma proteins to study doping in sport
    • Barton C, Beck P, Kay R, Teale P, Roberts J. Multiplexed LC-MS/MS analysis of horse plasma proteins to study doping in sport. Proteomics 9(11), 3058-3065 (2009).
    • (2009) Proteomics , vol.9 , Issue.11 , pp. 3058-3065
    • Barton, C.1    Beck, P.2    Kay, R.3    Teale, P.4    Roberts, J.5
  • 88
    • 0035695257 scopus 로고    scopus 로고
    • IGF-I plasma concentrations in non-treated horses and horses administered with methionyl equine somatotropin
    • Popot MA, Bobin S, Bonnaire Y, Delahaut PH, Closset J. IGF-I plasma concentrations in non-treated horses and horses administered with methionyl equine somatotropin. Res. Vet. Sci. 7, 167-173 (2001).
    • (2001) Res. Vet. Sci. , vol.7 , pp. 167-173
    • Popot, M.A.1    Bobin, S.2    Bonnaire, Y.3    Delahaut, P.H.4    Closset, J.5
  • 89
    • 34247476306 scopus 로고    scopus 로고
    • Effect of exercise, training, circadian rhythm, age, and sex on insulin-like growth factor-1 in the horse
    • Noble GK, Houghton E, Roberts CJ et al. Effect of exercise, training, circadian rhythm, age, and sex on insulin-like growth factor-1 in the horse. J. Anim. Sci. 85(1), 163-171 (2007).
    • (2007) J. Anim. Sci. , vol.85 , Issue.1 , pp. 163-171
    • Noble, G.K.1    Houghton, E.2    Roberts, C.J.3
  • 90
    • 0035190739 scopus 로고    scopus 로고
    • Approach to the determination of insulin-likegrowth- factor-I (IGF-I) concentration in plasma by high-performance liquid chromatography-ion trap MS: Use of a deconvolution algorithm for the quantification of multiprotonated molecules in electrospray ionization
    • Bobin S, Popot MA, Bonnaire Y, Tabet JC. Approach to the determination of insulin-likegrowth- factor-I (IGF-I) concentration in plasma by high-performance liquid chromatography-ion trap MS: use of a deconvolution algorithm for the quantification of multiprotonated molecules in electrospray ionization. Analyst 126, 1996-2001 (2001).
    • (2001) Analyst , vol.126 , pp. 1996-2001
    • Bobin, S.1    Popot, M.A.2    Bonnaire, Y.3    Tabet, J.C.4
  • 91
    • 0034912072 scopus 로고    scopus 로고
    • Growth hormone abuse in the horse: Preliminary assessment of a mass spectrometric procedure for IGF-1 identification and quantitation
    • de Kock SS, Rodgers JP, Swanepoel BC. Growth hormone abuse in the horse: preliminary assessment of a mass spectrometric procedure for IGF-1 identification and quantitation. Rapid Commun. Mass Spectrom. 15(14), 1191-1197 (2001).
    • (2001) Rapid Commun. Mass Spectrom. , vol.15 , Issue.14 , pp. 1191-1197
    • De Kock, S.S.1    Rodgers, J.P.2    Swanepoel, B.C.3
  • 92
    • 41149172494 scopus 로고    scopus 로고
    • Determination of IGF-I in horse plasma by LC electrospray ionisation MS
    • Popot MA, Woolfitt AR, Garcia P, Tabet JC. Determination of IGF-I in horse plasma by LC electrospray ionisation MS. Anal. Bioanal. Chem. 390(7), 1843-1852 (2008).
    • (2008) Anal. Bioanal. Chem. , vol.390 , Issue.7 , pp. 1843-1852
    • Popot, M.A.1    Woolfitt, A.R.2    Garcia, P.3    Tabet, J.C.4
  • 93
    • 38649129902 scopus 로고    scopus 로고
    • Detection of secondary biomarker of met-eGH as a strategy to screen for somatotrophin misuse in horseracing
    • Bailly-Chouriberry L, Chu-Van E, Pinel G et al. Detection of secondary biomarker of met-eGH as a strategy to screen for somatotrophin misuse in horseracing. Analyst 133(2), 270-276 (2007).
    • (2007) Analyst , vol.133 , Issue.2 , pp. 270-276
    • Bailly-Chouriberry, L.1    Chu-Van, E.2    Pinel, G.3
  • 94
    • 44349104139 scopus 로고    scopus 로고
    • Erythropoiesis-stimulating agents and other methods to enhance oxygen transport
    • Elliott S. Erythropoiesis-stimulating agents and other methods to enhance oxygen transport. Br. J. Pharmacol. 154(3), 529-541 (2008).
    • (2008) Br. J. Pharmacol. , vol.154 , Issue.3 , pp. 529-541
    • Elliott, S.1
  • 95
    • 33745782713 scopus 로고    scopus 로고
    • Effects of blood withdrawl and reinfusion on biomarkers of erythropoiesis in humans: Implications for anti-doping strategies
    • Damsgaard R, Munch T, Morkeberg J, Mortensen SP, Gonzalez-Alonso J. Effects of blood withdrawl and reinfusion on biomarkers of erythropoiesis in humans: Implications for anti-doping strategies. Haematologica 91, 1006-1008 (2006).
    • (2006) Haematologica , vol.91 , pp. 1006-1008
    • Damsgaard, R.1    Munch, T.2    Morkeberg, J.3    Mortensen, S.P.4    Gonzalez-Alonso, J.5
  • 96
    • 64249118992 scopus 로고    scopus 로고
    • Study of a new indirect method based on absolute norms of variation to detect autologous blood transfusion
    • Sallet P, Brunet-Guedj E, Mornex R, Baverel G. Study of a new indirect method based on absolute norms of variation to detect autologous blood transfusion. Int. J. Hematol. 88(4), 362-368 (2008).
    • (2008) Int. J. Hematol. , vol.88 , Issue.4 , pp. 362-368
    • Sallet, P.1    Brunet-Guedj, E.2    Mornex, R.3    Baverel, G.4
  • 97
    • 0345686665 scopus 로고    scopus 로고
    • Proof of homologous blood transfusion through quantification of blood group antigens
    • Nelson M, Popp H, Sharpe K, Ashenden MP. Proof of homologous blood transfusion through quantification of blood group antigens. Haematologica 88(11), 1284-1295 (2003).
    • (2003) Haematologica , vol.88 , Issue.11 , pp. 1284-1295
    • Nelson, M.1    Popp, H.2    Sharpe, K.3    Ashenden, M.P.4
  • 98
    • 0037227316 scopus 로고    scopus 로고
    • Erythropoietin: Physiology and pharmacology update
    • Fisher JW. Erythropoietin: physiology and pharmacology update. Exp. Biol. Med. 228, 1-14 (2003).
    • (2003) Exp. Biol. Med. , vol.228 , pp. 1-14
    • Fisher, J.W.1
  • 99
    • 34547365048 scopus 로고    scopus 로고
    • Procedures for monitoring recombinant erythropoietin and analogues in doping control
    • Segura J, Pascual JA, Gutiérrez-Gallego R. Procedures for monitoring recombinant erythropoietin and analogues in doping control. Anal. Bioanal. Chem. 388(7), 1521-1529 (2007).
    • (2007) Anal. Bioanal. Chem. , vol.388 , Issue.7 , pp. 1521-1529
    • Segura, J.1    Pascual, J.A.2    Gutiérrez-Gallego, R.3
  • 101
    • 0033774328 scopus 로고    scopus 로고
    • Reticulocyte parameters as potential discriminators of recombinant human erythropoietin abuse in elite athletes
    • Parisotto R, Gore CJ, Hahn AG et al. Reticulocyte parameters as potential discriminators of recombinant human erythropoietin abuse in elite athletes. Int J. Sports Med. 21(7), 471-479 (2000).
    • (2000) Int J. Sports Med. , vol.21 , Issue.7 , pp. 471-479
    • Parisotto, R.1    Gore, C.J.2    Hahn, A.G.3
  • 102
    • 0035103621 scopus 로고    scopus 로고
    • Detection of recombinant human erythropoietin abuse in athletes utilizing markers of altered erythropoiesis
    • Parisotto R, Wu M, Ashenden MJ et al. Detection of recombinant human erythropoietin abuse in athletes utilizing markers of altered erythropoiesis. Haematologica 86(2), 128-137 (2001).
    • (2001) Haematologica , vol.86 , Issue.2 , pp. 128-137
    • Parisotto, R.1    Wu, M.2    Ashenden, M.J.3
  • 103
    • 0034754202 scopus 로고    scopus 로고
    • A comparison of the physiological response to simulated altitude exposure and r-HuEpo administration
    • Ashenden MJ, Hahn AG, Martin DT, Logan P, Parisotto R, Gore CJ. A comparison of the physiological response to simulated altitude exposure and r-HuEpo administration. J. Sports. Sci. 19(11), 831-837 (2001).
    • (2001) J. Sports. Sci. , vol.19 , Issue.11 , pp. 831-837
    • Ashenden, M.J.1    Hahn, A.G.2    Martin, D.T.3    Logan, P.4    Parisotto, R.5    Gore, C.J.6
  • 104
    • 0036904798 scopus 로고    scopus 로고
    • Development of reference ranges in elite athletes for markers of altered erythropoiesis
    • Sharpe K, Hopkins W, Emslie KR et al. Development of reference ranges in elite athletes for markers of altered erythropoiesis. Haematologica 87(12), 1248-1257 (2002).
    • (2002) Haematologica , vol.87 , Issue.12 , pp. 1248-1257
    • Sharpe, K.1    Hopkins, W.2    Emslie, K.R.3
  • 105
    • 84906685904 scopus 로고    scopus 로고
    • Second-generation blood tests to detect erythropoietin abuse by athletes
    • Gore CJ, Parisotto R, Ashenden MJ et al. Second-generation blood tests to detect erythropoietin abuse by athletes. Haematologica 89(7), 891-892 (2004).
    • (2004) Haematologica , vol.89 , Issue.7 , pp. 891-892
    • Gore, C.J.1    Parisotto, R.2    Ashenden, M.J.3
  • 106
    • 33645392494 scopus 로고    scopus 로고
    • A third generation approach to detect erythropoietin abuse in athletes
    • Sharpe K, Ashenden MJ, Schumacher YO. A third generation approach to detect erythropoietin abuse in athletes. Haematologica 91(3), 356-363 (2006).
    • (2006) Haematologica , vol.91 , Issue.3 , pp. 356-363
    • Sharpe, K.1    Ashenden, M.J.2    Schumacher, Y.O.3
  • 107
    • 84906694348 scopus 로고    scopus 로고
    • UCI 2007 press release announcing plans to take samples for the biological passport in 2008
    • UCI 2007 press release announcing plans to take samples for the biological passport in 2008 www.uci.ch/modules/enews/enewsdetails.as p?menuid=mji0nq&id=ntqzoa&langid=1
  • 108
    • 84906711190 scopus 로고    scopus 로고
    • BikeRadar.com reports WADA support for UCI biological passport withdrawn
    • BikeRadar.com reports WADA support for UCI biological passport withdrawn www.bikeradar.com/news/article/ wada-pulls-athlete-passport-project-fromuci- 15344
  • 109
    • 84906711191 scopus 로고    scopus 로고
    • WADA athletes passport
    • WADA athletes passport www.wada-ama.org/en/dynamic. ch2?pageCategory.id= 754
  • 110
    • 84906677760 scopus 로고    scopus 로고
    • WADA Science and Medicine program
    • WADA Science and Medicine program www.wada-ama.org/en/dynamic. ch2?pageCategory.id=249
  • 111
    • 84906661351 scopus 로고    scopus 로고
    • Guidelines for blood sample collection
    • Guidelines for blood sample collection www.wada-ama.org/rtecontent/ document/2008-06-GuidelinesBloodSample-unmarked.pdf


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