Affinity-based biosensors as promising tools for gene doping detection

Trends in Biotechnology

Volumn 26, Issue 5, 2008, Pages 236-243

  Minunni, Maria ^a   Scarano, Simona ^a   Mascini, Marco ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DOPING (ADDITIVES); ENVIRONMENTAL IMPACT; GENES; PROBLEM SOLVING;

AFFINITY-BASED BIOSENSORS; ANTI-DOPING CONTROL; CLINICAL DIAGNOSTICS; GENE DOPING DETECTION;

BIOSENSORS;

HUMAN GROWTH HORMONE; RECOMBINANT ERYTHROPOIETIN; SOMATOMEDIN C;

ARTICLE; BIOSENSOR; DIAGNOSTIC TEST; DNA SEQUENCE; DOPING; ENVIRONMENTAL FACTOR; ENZYME LINKED IMMUNOSORBENT ASSAY; FOOD ANALYSIS; GENE EXPRESSION; GENE INSERTION; GENE THERAPY; GENETIC ANALYSIS; HUMORAL IMMUNITY; IMMUNOELECTROPHORESIS; IMMUNOSENSOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SURFACE PLASMON RESONANCE; TRANSGENE;

APTAMERS, NUCLEOTIDE; BIOSENSING TECHNIQUES; DNA, COMPLEMENTARY; DOPING IN SPORTS; GENE TRANSFER TECHNIQUES; GENETIC ENHANCEMENT; GENETIC VECTORS; HUMANS; IMMUNOASSAY; RECOMBINANT PROTEINS; SUBSTANCE ABUSE DETECTION; SURFACE PLASMON RESONANCE; TRANSGENES;

EID: 41949127013     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibtech.2008.02.005     Document Type: Article

References (48)

1. Patil S.D., et al. DNA-based therapeutics and DNA delivery systems: a comprehensive review. AAPS J. 7 (2005) E61-E77
2. Segura J., et al. Procedures for monitoring recombinant erythropoietin and analogues in doping control. Anal. Bioanal. Chem. 388 (2007) 1521-1529
3. Powrie J.K., et al. Detection of growth hormone abuse in sport. Growth Horm. IGF Res. 17 (2007) 220-226
4. Schneider A.J., and Friedmann T. Gene doping in sports: the science and ethics of genetically modified athletes. Adv. Genet. 51 (2006) 1-110
5. Scollay R. Gene therapy: a brief overview of the past, present, and future. Ann. N. Y. Acad. Sci. 953 (2001) 26-30
6. Zhou S., et al. Adeno-associated virus-mediated delivery of erythropoietin leads to sustained elevation of hematocrit in nonhuman primates. Gene Ther. 5 (1998) 665-670
7. Simpson A.H., et al. The role of growth factors and related agents in accelerating fracture healing. J. Bone Joint Surg. Br. 88 (2006) 701-705
8. Barton E.R. Viral expression of insulin-like growth factor-I isoforms promotes different responses in skeletal muscle. J. Appl. Physiol. 100 (2006) 1778-1784
9. Schertzer J.D., et al. Systemic administration of IGF-I enhances oxidative status and reduces contraction-induced injury in skeletal muscles of mdx dystrophic mice. Am. J. Physiol. Endocrinol. Metab. 291 (2006) 499-505
10. Barton-Davis E.R., et al. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 15603-15607
11. Sweeney H.L. Gene doping. Sci. Am. 291 (2004) 62-69
12. DeFrancesco L. The faking of champions. Nat. Biotechnol. 22 (2004) 1069-1071
13. Baumgartner I., et al. Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 97 (1998) 1114-1123
14. Wang Y.X., et al. Regulation of muscle fiber type and running endurance by PPARδ. PLoS Biol. 2 (2004) 1532-1539
15. Matsakas A., and Diel P. The growth factor myostatin, a key regulator in skeletal muscle growth and homeostasis. Int. J. Sports Med. 26 (2005) 83-89
16. Azzazy H.M.E., and Mansour M.M.H. Rogue athletes and recombinant DNA technology: challenges for doping control. Analyst 132 (2007) 951-957
17. Baoutina A., et al. Developing strategies for detection of gene doping. J. Gene Med. 10 (2008) 3-20
18. Palmer D.H., et al. Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer. J. Clin. Oncol. 22 (2004) 1546-1552
19. McCullough B., et al. Beth erythropoietin gene therapy leads to autoimmune anemia in macaques. Blood 103 (2004) 3300-3302
20. In: Turner A.P.F., et al. (Ed). Biosensors: Fundamentals and Applications (1987), Oxford University Press
21. Ricci F., et al. A review on novel developments and applications of immunosensors in food analysis. Anal. Chim. Acta 605 (2007) 111-129
22. Tombelli S., et al. Analytical application of aptamers. Biosens. Bioelectron. 20 (2005) 2424-2434
23. Li Y., et al. Detection of protein biomarkers using RNA aptamer microarrays and enzymatically amplified surface plasmon resonance imaging. Anal. Chem. 79 (2007) 1082-1088
24. McCauley T.G., et al. Aptamer-based biosensor arrays for detection and quantification of biological macromolecules. Anal. Biochem. 319 (2003) 244-250
25. Guidi A., et al. Comparison of a conventional immunoassay (ELISA) with a surface plasmon resonance-based biosensor for IGF-1 detection in cows' milk. Biosens. Bioelectron. 16 (2001) 971-977
26. Mani J.C., et al. Accurate topological comparison of two recombinant human growth hormones by optical surface plasmon resonance. Anal. Biochem. 248 (1997) 50-62
27. Bleiziffer O., et al. Gene transfer strategies in tissue engineering. J. Cell. Mol. Med. 11 (2007) 206-223
28. Gerdes C.A., et al. Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo. Mol. Ther. 2 (2000) 330-338
29. Line R.L., and Rust G.S. Acute exertional rhabdomyolysis. Am. Fam. Physician 52 (1995) 502-506
30. Santos Jr. J. Exertional rhabdomyolysis. Potentially life-threatening consequence of intense exercise. J.A.A.P.A. 12 (1999) 46-49 53-55
31. Dunn A., and Donnelly S. The role of the kidney in blood volume regulation: the kidney as a regulator of the hematocrit. Am. J. Med. Sci. 334 (2007) 65-71
32. Ye X., et al. Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer. Science 283 (1999) 88-91
33. Lucarelli F., et al. Enzyme-based impedimetric detection of PCR products using oligonucleotide-modified screen-printed gold electrodes. Biosens. Bioelectron. 20 (2005) 2001-2009
34. Mariotti E., et al. Surface plasmon resonance biosensor for genetically modified organisms detection. Anal. Chim. Acta 453 (2002) 165-172
35. Mannelli I., et al. Quartz crystal microbalance (QCM) affinity biosensor for genetically modified organisms (GMOs) detection. Biosens. Bioelectron. 18 (2003) 129-140
36. Minunni M., et al. Detection of fragmented genomic DNA by PCR-free piezoelectric sensing using a denaturation approach. J. Am. Chem. Soc. 127 (2005) 7966-7967
37. th Italian Conference: 2007 February 12-14; Naples (Siciliano, A., ed.), pp. 175-181, World Scientific Publishing Co. Pte. Ltd
38. Fang S., et al. Attomole microarray detection of microRNAs by nanoparticle-amplified SPR imaging measurements of surface polyadenylation reactions. J. Am. Chem. Soc. 128 (2006) 14044-14046
39. Lecaruyer P., et al. Surface plasmon resonance imaging as a multidimensional surface characterization instrument - application to biochip genotyping. Anal. Chim. Acta 573-574 (2006) 333-340
40. Lasne F., et al. Detection of isoelectric profiles of erythropoietin in urine: differentiation of natural and administered recombinant hormones. Anal. Biochem. 311 (2002) 119-126
41. Lasne F., et al. Genetic doping with erythropoietin cDNA in primate muscle is detectable. Mol. Ther. 10 (2004) 409-410
42. Lasne F. Double-blotting: a solution to the problem of non-speficifc binding of secondary antibodies in immunoblotting procedured. J. Immunol. Methods 253 (2001) 125-131
43. Lasne F., et al. Detection of recombinant human erythropoietin in urine for doping analysis: interpretation of isoelectric profiles by discriminant analysis. Electrophoresis 28 (2007) 1875-1881
44. Marco M.P., et al. Immunochemical techniques for environmental analysis. I. Immunosensors. Trends Analyt. Chem. 14 (1995) 341-350
45. Mason S., et al. Validation of the BIACORE 3000 platform for detection of antibodies against erythropoietic agents in human serum samples. Curr. Med. Res. Opin. 19 (2003) 651-659
46. Li, W. (2001) Bioage Pharmaceuticals, Inc. Method of isolating target specific oligonucleotide ligands (WO/1999/054506), PCT/US1999/008561
47. Sobarzo A., et al. Optical fiber immunosensor for the detection of IgG antibody to Rift Valley fever virus in humans. J. Virol. Methods 146 (2007) 327-334
48. Ionescu R.E., et al. Amperometric immunosensor for the detection of anti-West Nile virus IgG. Anal. Chem. 79 (2007) 8662-8668