Circulating nucleic acids in the assessment of endogenous growth hormone production

Annals of the New York Academy of Sciences

Volumn 1137, Issue , 2008, Pages 58-65

  Thakkar, H ^a   Butt, A N ^a   Powrie, J ^a   Holt, R ^b   Swaminathan, R ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b Southampton   (United Kingdom)

Author keywords

Acromegaly; GHRH; Growth hormone; IGF 1; mRNA

Indexed keywords

GROWTH HORMONE; MESSENGER RNA; NUCLEIC ACID; RECOMBINANT GROWTH HORMONE;

ACROMEGALY; ADULT; BLOOD SAMPLING; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; HORMONE DETERMINATION; HORMONE SYNTHESIS; HUMAN; HUMAN TISSUE; MALE; REAL TIME POLYMERASE CHAIN REACTION;

EID: 52249105352     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1448.003     Document Type: Conference Paper

References (19)

1. Sönksen, P.H. 2001. Insulin, growth hormone and sport. J. Endocrinol. 170 : 13 25.
2. World Anti-Doping Agency. 2006. Prohibited List [online]. Available at http://www.wada-ama.org/rtecontent/document/2006_LIST.pdf.
3. Rigamonti, A.E. et al. 2005. Growth hormone abuse: methods of detection. Trends Endocrinol. Metab. 16 : 160 166.
4. Vogel, G. 2004. A race to the starting line. Science 305 : 632 635.
5. McHugh, C.M. et al. 2005. Challenges in detecting the abuse of growth hormone in sport. Clin. Chem. 51 : 1587 1593.
6. Bidlingmaier, M. et al. 2001. Doping with growth hormone. J. Pediatr. Endocrinol. Metab. 14 : 1077 1084.
7. Wallace, J.D. et al. 2001. Changes in non-22-kilodalton (kDa) isoforms of growth hormone (GH) after administration of 22-kDa recombinant human GH in trained adult males. J. Clin. Endocrinol. Metab. 86 : 1731 1737.
8. Tsang, J.C. & Y.M. Lo. 2007. Circulating nucleic acids in plasma/serum. Pathology 39 : 197 207.
9. T method. Methods 25 : 402 408.
10. Hossain, B. & W.M. Drake. 2005. Acromegaly. Medicine 33 : 14 16.
11. Veldhuis, J.D. & C.Y. Bowers. 2003. Three-peptide control of pulsatile and entropic feedback-sensitive modes of growth hormone secretion: modulation by estrogen and aromatizable androgen. J. Pediatr. Endocrinol. Metab. 16 (Suppl. 3 587 605.
12. Kola, B. et al. 2003. Reduced expression of the growth hormone and type 1 insulin-like growth factor receptors in human somatotroph tumours and an analysis of possible mutations of the growth hormone receptor. Clin. Endocrinol. (Oxf.) 59 : 328 338.
13. Sato, M. & L.A. Frohman. 1993. Differential effects of central and peripheral administration of growth hormone (GH) and insulin-like growth factor on hypothalamic GH-releasing hormone and somatostatin gene expression in GH-deficient dwarf rats. Endocrinology 133 : 793 799.
14. Toogood, A.A. & S.M. Shalet. 1998. Ageing and growth hormone status. Baillieres Clin. Endocrinol. Metab. 12 : 281 296.
15. Corpas, E. et al. 1992. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men. J. Clin. Endocrinol. Metab. 75 : 530 535.
16. Corpas, E. et al. 1993. Continuous subcutaneous infusions of growth hormone (GH) releasing hormone 1-44 for 14 days increase GH and insulin-like growth factor-I levels in old men. J. Clin. Endocrinol. Metab. 76 : 134 138.
17. Misra, M. et al. 2003. Alterations in growth hormone secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism. J. Clin. Endocrinol. Metab. 88 : 5615 5623.
18. Ng, E.K. et al. 2003. mRNA of placental origin is readily detectable in maternal plasma. Proc. Natl. Acad. Sci. USA 100 : 4748 4753.
19. Farina, A. et al. 2004. Circulating corticotropin-releasing hormone mRNA in maternal plasma: relationship with gestational age and severity of preeclampsia. Clin. Chem. 50 : 1851 1854.