Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor

Journal of Biological Chemistry

Volumn 286, Issue 14, 2011, Pages 12450-12460

  Hwang, Jungwon ^a,b   Kim, Yoonjeong ^a,c   Kang, Ho Bum ^a   Jaroszewski, Lukasz ^d   Deacon, Ashley M ^e   Lee, Hwiseop ^a   Choi, Won Chan ^a   Kim, Kyung Jin ^f   Kim, Cheol Hee ^g   Kang, Beom Sik ^c   Lee, Jie Oh ^b   Oh, Tae Kwang ^a   Kim, Jae Wha ^a   Wilson, Ian A ^h   Kima, Myung Hee ^a,i  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Kyungpook National University   (South Korea)

^d BURNHAM INSTITUTE   (United States)

^e SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^f Pohang University of Science and Technology (POSTECH)   (South Korea)

^g Chungnam National University   (South Korea)

^h SCRIPPS RESEARCH INSTITUTE   (United States)

ⁱ University of Science and Technology (UST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BELONG TO; CATENIN SIGNALING; COLORECTAL CANCER; HUMAN CANCER; NON-ENZYMATIC; PRIMARY AMINO ACID; REGULATED GENES; SEQUENCE SIMILARITY; STRUCTURAL FEATURE; STRUCTURAL SIMILARITY; SUBSTRATE-BINDING SITES; TUMOR SUPPRESSORS; TUMORIGENESIS;

ACTIVE NETWORKS; AMINO ACIDS; DISEASES; GENES; MOLECULAR INTERACTIONS; MOLECULAR STRUCTURE; PROTEINS; STRUCTURAL ANALYSIS; TUMORS;

CRYSTAL STRUCTURE;

BETA CATENIN; MEMBRANE PROTEIN; N MYC DOWNSTREAM REGULATED GENE 2 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; CRYSTALLIZATION; HUMAN; MOLECULAR INTERACTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; TUMOR SUPPRESSOR PROTEINS;

EID: 79953315776     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.170803     Document Type: Article

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