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Volumn 233, Issue 1-2, 2011, Pages 73-79

Chronic stress promotes lymphocyte reduction through TLR2 mediated PI3K signaling in a β-arrestin 2 dependent manner

Author keywords

Arrestin 2; Akt; Lymphocytes; PI3K; Stress; TLR2

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BETA ARRESTIN 2; LIPOPEPTIDE; PEPTIDOGLYCAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TOLL LIKE RECEPTOR 2; WORTMANNIN;

EID: 79953305642     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2010.11.015     Document Type: Article
Times cited : (19)

References (55)
  • 2
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • Aderem A., Ulevitch R.J. Toll-like receptors in the induction of the innate immune response. Nature 2000, 406:782-787.
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 3
    • 0035115257 scopus 로고    scopus 로고
    • Growth factor-stimulated phosphorylation of Akt and p70(S6K) is differentially inhibited by LY294002 and Wortmannin
    • Adi S., Wu N.Y., Rosenthal S.M. Growth factor-stimulated phosphorylation of Akt and p70(S6K) is differentially inhibited by LY294002 and Wortmannin. Endocrinology 2001, 142:498-501.
    • (2001) Endocrinology , vol.142 , pp. 498-501
    • Adi, S.1    Wu, N.Y.2    Rosenthal, S.M.3
  • 5
    • 22744449073 scopus 로고    scopus 로고
    • An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
    • Beaulieu J.M., Sotnikova T.D., Marion S., Lefkowitz R.J., Gainetdinov R.R., Caron M.G. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 2005, 122:261-273.
    • (2005) Cell , vol.122 , pp. 261-273
    • Beaulieu, J.M.1    Sotnikova, T.D.2    Marion, S.3    Lefkowitz, R.J.4    Gainetdinov, R.R.5    Caron, M.G.6
  • 7
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley L.C. The phosphoinositide 3-kinase pathway. Science 2002, 296:1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 8
    • 34249033790 scopus 로고    scopus 로고
    • Chronic foot shock induces hyperactive behaviors and accompanying pro- and anti-inflammatory responses in mice
    • Cao L., Hudson C.A., Moynihan J.A. Chronic foot shock induces hyperactive behaviors and accompanying pro- and anti-inflammatory responses in mice. J. Neuroimmunol. 2007, 186:63-74.
    • (2007) J. Neuroimmunol. , vol.186 , pp. 63-74
    • Cao, L.1    Hudson, C.A.2    Moynihan, J.A.3
  • 9
    • 0037450804 scopus 로고    scopus 로고
    • Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide
    • Caramalho I., Lopes-Carvalho T., Ostler D., Zelenay S., Haury M., Demengeot J. Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide. J. Exp. Med. 2003, 197:403-411.
    • (2003) J. Exp. Med. , vol.197 , pp. 403-411
    • Caramalho, I.1    Lopes-Carvalho, T.2    Ostler, D.3    Zelenay, S.4    Haury, M.5    Demengeot, J.6
  • 10
    • 0031415757 scopus 로고    scopus 로고
    • Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: a potential role for leukocyte trafficking
    • Dhabhar F.S., McEwen B.S. Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: a potential role for leukocyte trafficking. Brain Behav. Immun. 1997, 11:286-306.
    • (1997) Brain Behav. Immun. , vol.11 , pp. 286-306
    • Dhabhar, F.S.1    McEwen, B.S.2
  • 11
    • 0033514465 scopus 로고    scopus 로고
    • Enhancing versus suppressive effects of stress hormones on skin immune function
    • Dhabhar F.S., McEwen B.S. Enhancing versus suppressive effects of stress hormones on skin immune function. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:1059-1064.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 1059-1064
    • Dhabhar, F.S.1    McEwen, B.S.2
  • 12
    • 33749152085 scopus 로고    scopus 로고
    • Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity
    • Doyle S.L., O'Neill L.A. Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity. Biochem. Pharmacol. 2006, 72:1102-1113.
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1102-1113
    • Doyle, S.L.1    O'Neill, L.A.2
  • 14
    • 0038516745 scopus 로고    scopus 로고
    • Neuroimmunology and inflammation: implications for therapy of allergic and autoimmune diseases
    • Frieri M. Neuroimmunology and inflammation: implications for therapy of allergic and autoimmune diseases. Ann. Allergy Asthma Immunol. 2003, 90:34-40.
    • (2003) Ann. Allergy Asthma Immunol. , vol.90 , pp. 34-40
    • Frieri, M.1
  • 15
    • 0036199607 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase in immunological systems
    • Fruman D.A., Cantley L.C. Phosphoinositide 3-kinase in immunological systems. Semin. Immunol. 2002, 14:7-18.
    • (2002) Semin. Immunol. , vol.14 , pp. 7-18
    • Fruman, D.A.1    Cantley, L.C.2
  • 16
    • 0037629646 scopus 로고    scopus 로고
    • PI3K and negative regulation of TLR signaling
    • Fukao T., Koyasu S. PI3K and negative regulation of TLR signaling. Trends Immunol. 2003, 24:358-363.
    • (2003) Trends Immunol. , vol.24 , pp. 358-363
    • Fukao, T.1    Koyasu, S.2
  • 18
    • 33845908490 scopus 로고    scopus 로고
    • Regulations and roles of the interleukin-1 receptor associated kinases (IRAKs) in innate and adaptive immunity
    • Gan L., Li L. Regulations and roles of the interleukin-1 receptor associated kinases (IRAKs) in innate and adaptive immunity. Immunol. Res. 2006, 35:295-302.
    • (2006) Immunol. Res. , vol.35 , pp. 295-302
    • Gan, L.1    Li, L.2
  • 19
    • 0037199972 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
    • Guha M., Mackman N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J. Biol. Chem. 2002, 277:32124-32132.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32124-32132
    • Guha, M.1    Mackman, N.2
  • 22
    • 0346146996 scopus 로고    scopus 로고
    • Regulation of dendritic cell function through Toll-like receptors
    • Kaisho T., Akira S. Regulation of dendritic cell function through Toll-like receptors. Curr. Mol. Med. 2003, 3:373-385.
    • (2003) Curr. Mol. Med. , vol.3 , pp. 373-385
    • Kaisho, T.1    Akira, S.2
  • 23
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death
    • Karin M., Lin A. NF-kappaB at the crossroads of life and death. Nat. Immunol. 2002, 3:221-227.
    • (2002) Nat. Immunol. , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 24
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by beta-arrestins
    • Lefkowitz R.J., Shenoy S.K. Transduction of receptor signals by beta-arrestins. Science 2005, 308:512-517.
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 25
    • 1142309739 scopus 로고    scopus 로고
    • Modulating Toll-like receptor mediated signaling by (1→3)-beta-D-glucan rapidly induces cardioprotection
    • Li C., Ha T., Kelley J., Gao X., Qiu Y., Kao R.L., Browder W., Williams D.L. Modulating Toll-like receptor mediated signaling by (1→3)-beta-D-glucan rapidly induces cardioprotection. Cardiovasc. Res. 2004, 61:538-547.
    • (2004) Cardiovasc. Res. , vol.61 , pp. 538-547
    • Li, C.1    Ha, T.2    Kelley, J.3    Gao, X.4    Qiu, Y.5    Kao, R.L.6    Browder, W.7    Williams, D.L.8
  • 27
    • 77954528269 scopus 로고    scopus 로고
    • Beta-Arrestin 2 regulates toll-like receptor 4-mediated apoptotic signalling through glycogen synthase kinase-3beta
    • Li H., Sun X., LeSage G., Zhang Y., Liang Z., Chen J., Hanley G., He L., Sun S., Yin D. Beta-Arrestin 2 regulates toll-like receptor 4-mediated apoptotic signalling through glycogen synthase kinase-3beta. Immunology 2010, 130:556-563.
    • (2010) Immunology , vol.130 , pp. 556-563
    • Li, H.1    Sun, X.2    LeSage, G.3    Zhang, Y.4    Liang, Z.5    Chen, J.6    Hanley, G.7    He, L.8    Sun, S.9    Yin, D.10
  • 28
    • 29244452161 scopus 로고    scopus 로고
    • Beta-arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-kappaB activation
    • Luan B., Zhang Z., Wu Y., Kang J., Pei G. Beta-arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-kappaB activation. EMBO J. 2005, 24:4237-4246.
    • (2005) EMBO J. , vol.24 , pp. 4237-4246
    • Luan, B.1    Zhang, Z.2    Wu, Y.3    Kang, J.4    Pei, G.5
  • 31
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R., Preston-Hurlburt P., Janeway C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997, 388:394-397.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway, C.A.3
  • 32
    • 33947314576 scopus 로고    scopus 로고
    • Regulation of receptor trafficking by GRKs and arrestins
    • Moore C.A., Milano S.K., Benovic J.L. Regulation of receptor trafficking by GRKs and arrestins. Annu. Rev. Physiol. 2007, 69:451-482.
    • (2007) Annu. Rev. Physiol. , vol.69 , pp. 451-482
    • Moore, C.A.1    Milano, S.K.2    Benovic, J.L.3
  • 33
    • 0037352702 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages
    • Ojaniemi M., Glumoff V., Harju K., Liljeroos M., Vuori K., Hallman M. Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages. Eur. J. Immunol. 2003, 33:597-605.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 597-605
    • Ojaniemi, M.1    Glumoff, V.2    Harju, K.3    Liljeroos, M.4    Vuori, K.5    Hallman, M.6
  • 34
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill L.A., Bowie A.G. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 2007, 7:353-364.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 36
    • 4644292447 scopus 로고    scopus 로고
    • Stress, depression, the immune system, and cancer
    • Reiche E.M., Nunes S.O., Morimoto H.K. Stress, depression, the immune system, and cancer. Lancet Oncol. 2004, 5:617-625.
    • (2004) Lancet Oncol. , vol.5 , pp. 617-625
    • Reiche, E.M.1    Nunes, S.O.2    Morimoto, H.K.3
  • 37
    • 2642531082 scopus 로고    scopus 로고
    • Arrestins block G protein-coupled receptor-mediated apoptosis
    • Revankar C.M., Vines C.M., Cimino D.F., Prossnitz E.R. Arrestins block G protein-coupled receptor-mediated apoptosis. J. Biol. Chem. 2004, 279:24578-24584.
    • (2004) J. Biol. Chem. , vol.279 , pp. 24578-24584
    • Revankar, C.M.1    Vines, C.M.2    Cimino, D.F.3    Prossnitz, E.R.4
  • 38
    • 33646896934 scopus 로고    scopus 로고
    • New players in TLR-mediated innate immunity: PI3K and small Rho GTPases
    • Ruse M., Knaus U.G. New players in TLR-mediated innate immunity: PI3K and small Rho GTPases. Immunol. Res. 2006, 34:33-48.
    • (2006) Immunol. Res. , vol.34 , pp. 33-48
    • Ruse, M.1    Knaus, U.G.2
  • 40
    • 7544225495 scopus 로고    scopus 로고
    • Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling
    • Sarkar S.N., Peters K.L., Elco C.P., Sakamoto S., Pal S., Sen G.C. Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling. Nat. Struct. Mol. Biol. 2004, 11:1060-1067.
    • (2004) Nat. Struct. Mol. Biol. , vol.11 , pp. 1060-1067
    • Sarkar, S.N.1    Peters, K.L.2    Elco, C.P.3    Sakamoto, S.4    Pal, S.5    Sen, G.C.6
  • 41
    • 0037294031 scopus 로고    scopus 로고
    • Stressed to death: implication of lymphocyte apoptosis for psychoneuroimmunology
    • Shi Y., Devadas S., Greeneltch K.M., Yin D., Allan M.R., Zhou J.N. Stressed to death: implication of lymphocyte apoptosis for psychoneuroimmunology. Brain Behav. Immun. 2003, 17(Suppl 1):S18-S26.
    • (2003) Brain Behav. Immun. , vol.17 , Issue.SUPPL. 1
    • Shi, Y.1    Devadas, S.2    Greeneltch, K.M.3    Yin, D.4    Allan, M.R.5    Zhou, J.N.6
  • 42
    • 31344463886 scopus 로고    scopus 로고
    • Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
    • Wang Y., Tang Y., Teng L., Wu Y., Zhao X., Pei G. Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 2006, 7:139-147.
    • (2006) Nat. Immunol. , vol.7 , pp. 139-147
    • Wang, Y.1    Tang, Y.2    Teng, L.3    Wu, Y.4    Zhao, X.5    Pei, G.6
  • 43
    • 2942554958 scopus 로고    scopus 로고
    • Beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha
    • Witherow D.S., Garrison T.R., Miller W.E., Lefkowitz R.J. beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:8603-8607.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 8603-8607
    • Witherow, D.S.1    Garrison, T.R.2    Miller, W.E.3    Lefkowitz, R.J.4
  • 44
    • 23044454798 scopus 로고    scopus 로고
    • Expression and function of Toll-like receptor on T cells
    • Xu D., Komai-Koma M., Liew F.Y. Expression and function of Toll-like receptor on T cells. Cell. Immunol. 2005, 233:85-89.
    • (2005) Cell. Immunol. , vol.233 , pp. 85-89
    • Xu, D.1    Komai-Koma, M.2    Liew, F.Y.3
  • 45
    • 0038667903 scopus 로고    scopus 로고
    • Stress-associated immunomodulation and its implications for responses to vaccination
    • Yang E.V., Glaser R. Stress-associated immunomodulation and its implications for responses to vaccination. Expert Rev. Vaccines 2002, 1:453-459.
    • (2002) Expert Rev. Vaccines , vol.1 , pp. 453-459
    • Yang, E.V.1    Glaser, R.2
  • 47
    • 0034678451 scopus 로고    scopus 로고
    • Chronic restraint stress promotes lymphocyte apoptosis by modulating CD95 expression
    • Yin D., Tuthill D., Mufson R.A., Shi Y. Chronic restraint stress promotes lymphocyte apoptosis by modulating CD95 expression. J. Exp. Med. 2000, 191:1423-1428.
    • (2000) J. Exp. Med. , vol.191 , pp. 1423-1428
    • Yin, D.1    Tuthill, D.2    Mufson, R.A.3    Shi, Y.4
  • 48
    • 33646098688 scopus 로고    scopus 로고
    • Morphine promotes Jurkat cell apoptosis through pro-apoptotic FADD/P53 and anti-apoptotic PI3K/Akt/NF-kappaB pathways
    • Yin D., Woodruff M., Zhang Y., Whaley S., Miao J., Ferslew K., Zhao J., Stuart C. Morphine promotes Jurkat cell apoptosis through pro-apoptotic FADD/P53 and anti-apoptotic PI3K/Akt/NF-kappaB pathways. J. Neuroimmunol. 2006, 174:101-107.
    • (2006) J. Neuroimmunol. , vol.174 , pp. 101-107
    • Yin, D.1    Woodruff, M.2    Zhang, Y.3    Whaley, S.4    Miao, J.5    Ferslew, K.6    Zhao, J.7    Stuart, C.8
  • 51
    • 0035164415 scopus 로고    scopus 로고
    • Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity
    • Zhang G., Ghosh S. Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity. J. Clin. Invest. 2001, 107:13-19.
    • (2001) J. Clin. Invest. , vol.107 , pp. 13-19
    • Zhang, G.1    Ghosh, S.2
  • 54
    • 54349096743 scopus 로고    scopus 로고
    • Chronic restraint stress promotes immune suppression through toll-like receptor 4-mediated phosphoinositide 3-kinase signaling
    • Zhang Y., Zhang Y., Miao J., Hanley G., Stuart C., Sun X., Chen T., Yin D. Chronic restraint stress promotes immune suppression through toll-like receptor 4-mediated phosphoinositide 3-kinase signaling. J. Neuroimmunol. 2008, 204:13-19.
    • (2008) J. Neuroimmunol. , vol.204 , pp. 13-19
    • Zhang, Y.1    Zhang, Y.2    Miao, J.3    Hanley, G.4    Stuart, C.5    Sun, X.6    Chen, T.7    Yin, D.8


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