-
1
-
-
0036731990
-
Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface
-
Graf, G. A., Li, W.-P., Gerard, R. D., Gelissen, I., White, A., Cohen, J. C., and Hobbs, H. H. (2002) Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface. J. Clin. Invest. 110, 659-669.
-
(2002)
J. Clin. Invest
, vol.110
, pp. 659-669
-
-
Graf, G.A.1
Li, W.-P.2
Gerard, R.D.3
Gelissen, I.4
White, A.5
Cohen, J.C.6
Hobbs, H.H.7
-
2
-
-
0348111456
-
ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion
-
Graf, G. A., Yu, L., Li, W. P., Gerard, R., Tuma, P. L., Cohen, J. C., and Hobbs, H. H. (2003) ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. J. Biol. Chem. 278, 48275-48282.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 48275-48282
-
-
Graf, G.A.1
Yu, L.2
Li, W.P.3
Gerard, R.4
Tuma, P.L.5
Cohen, J.C.6
Hobbs, H.H.7
-
3
-
-
17744390348
-
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
-
Berge, K. E., Tian, H., Graf, G. A., Yu, L., Grishin, N. V., Schultz, J., Kwiterovich, P., Shan, B., Barnes, R., and Hobbs, H. H. (2000) Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290, 1771-1775.
-
(2000)
Science
, vol.290
, pp. 1771-1775
-
-
Berge, K.E.1
Tian, H.2
Graf, G.A.3
Yu, L.4
Grishin, N.V.5
Schultz, J.6
Kwiterovich, P.7
Shan, B.8
Barnes, R.9
Hobbs, H.H.10
-
4
-
-
0035158733
-
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption
-
Lee, M. H., Lu, K., Hazard, S., Yu, H., Shulenin, S., Hidaka, H., Kojima, H., Allikmets, R., Sakuma, N., Pegoraro, R., Srivastava, A. K., Salen, G., Dean, M., and Patel, S. B. (2001) Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat. Genet. 27, 79-83.
-
(2001)
Nat. Genet
, vol.27
, pp. 79-83
-
-
Lee, M.H.1
Lu, K.2
Hazard, S.3
Yu, H.4
Shulenin, S.5
Hidaka, H.6
Kojima, H.7
Allikmets, R.8
Sakuma, N.9
Pegoraro, R.10
Srivastava, A.K.11
Salen, G.12
Dean, M.13
Patel, S.B.14
-
5
-
-
0037058995
-
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
-
Yu, L., Hammer, R. E., Li-Hawkins, J., von Bergmann, K., Lutjohann, D., Cohen, J. C., and Hobbs, H. H. (2002) Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc. Natl. Acad. Sci. U.S.A. 99, 16237-16242.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 16237-16242
-
-
Yu, L.1
Hammer, R.E.2
Li-Hawkins, J.3
von Bergmann, K.4
Lutjohann, D.5
Cohen, J.C.6
Hobbs, H.H.7
-
6
-
-
0036733630
-
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
-
Yu, L., Li-Hawkins, J., Hammer, R. E., Berge, K. E., Horton, J. D., Cohen, J. C., and Hobbs, H. H. (2002) Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J. Clin. Invest. 110, 671-680.
-
(2002)
J. Clin. Invest
, vol.110
, pp. 671-680
-
-
Yu, L.1
Li-Hawkins, J.2
Hammer, R.E.3
Berge, K.E.4
Horton, J.D.5
Cohen, J.C.6
Hobbs, H.H.7
-
7
-
-
0037687369
-
Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice
-
Kosters, A., Frijters, R. J., Schaap, F. G., Vink, E., Plosch, T., Ottenhoff, R., Jirsa, M., de Cuyper, I. M., Kuipers, F., and Groen, A. K. (2003) Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice. J. Hepatol. 38, 710-716.
-
(2003)
J. Hepatol
, vol.38
, pp. 710-716
-
-
Kosters, A.1
Frijters, R.J.2
Schaap, F.G.3
Vink, E.4
Plosch, T.5
Ottenhoff, R.6
Jirsa, M.7
de Cuyper, I.M.8
Kuipers, F.9
Groen, A.K.10
-
8
-
-
9144236921
-
Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor
-
Plosch, T., Bloks, V. W., Terasawa, Y., Berdy, S., Siegler, K., van der Sluijs, F., Kema, I. P., Groen, A. K., Shan, B., Kuipers, F., and Schwarz, M. (2004) Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor. Gastroenterology 126, 290-300.
-
(2004)
Gastroenterology
, vol.126
, pp. 290-300
-
-
Plosch, T.1
Bloks, V.W.2
Terasawa, Y.3
Berdy, S.4
Siegler, K.5
van der Sluijs, F.6
Kema, I.P.7
Groen, A.K.8
Shan, B.9
Kuipers, F.10
Schwarz, M.11
-
9
-
-
3042601466
-
A mouse model of sitosterolemia: Absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol
-
Klett, E. L., Lu, K., Kosters, A., Vink, E., Lee, M. H., Altenburg, M., Shefer, S., Batta, A. K., Yu, H., Chen, J., Klein, R., Looije, N., Oude-Elferink, R., Groen, A. K., Maeda, N., Salen, G., and Patel, S. B. (2004) A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. BMC Med. 2, 5.
-
(2004)
BMC Med
, vol.2
, pp. 5
-
-
Klett, E.L.1
Lu, K.2
Kosters, A.3
Vink, E.4
Lee, M.H.5
Altenburg, M.6
Shefer, S.7
Batta, A.K.8
Yu, H.9
Chen, J.10
Klein, R.11
Looije, N.12
Oude-Elferink, R.13
Groen, A.K.14
Maeda, N.15
Salen, G.16
Patel, S.B.17
-
10
-
-
2542427448
-
Hepatic ABCG5 and ABCG8 overexpression increases hepatobiliary sterol transport but does not alter aortic atherosclerosis in transgenic mice
-
Wu, J. E., Basso, F., Shamburek, R. D., Amar, M. J., Vaisman, B., Szakacs, G., Joyce, C., Tansey, T., Freeman, L., Paigen, B. J., Thomas, F., Brewer, H. B., Jr., and Santamarina-Fojo, S. (2004) Hepatic ABCG5 and ABCG8 overexpression increases hepatobiliary sterol transport but does not alter aortic atherosclerosis in transgenic mice. J. Biol. Chem. 279, 22913-22925.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 22913-22925
-
-
Wu, J.E.1
Basso, F.2
Shamburek, R.D.3
Amar, M.J.4
Vaisman, B.5
Szakacs, G.6
Joyce, C.7
Tansey, T.8
Freeman, L.9
Paigen, B.J.10
Thomas, F.11
Brewer Jr., H.B.12
Santamarina-Fojo, S.13
-
11
-
-
33748758161
-
Sterol transfer by ABCG5 and ABCG8: In vitro assay and reconstitution
-
Wang, J., Sun, F., Zhang, D.-w., Ma, Y., Xu, F., Belani, J. D., Cohen, J. C., Hobbs, H. H., and Xie, X.-S. (2006) Sterol transfer by ABCG5 and ABCG8: In vitro assay and reconstitution. J. Biol. Chem. 281, 27894-27904.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 27894-27904
-
-
Wang, J.1
Sun, F.2
Zhang, D.-W.3
Ma, Y.4
Xu, F.5
Belani, J.D.6
Cohen, J.C.7
Hobbs, H.H.8
Xie, X.-S.9
-
12
-
-
33645244155
-
Functional asymmetry of nucleotide-binding domains in ABCG5 and ABCG8
-
Zhang, D. W., Graf, G. A., Gerard, R. D., Cohen, J. C., and Hobbs, H. H. (2006) Functional asymmetry of nucleotide-binding domains in ABCG5 and ABCG8. J. Biol. Chem. 281, 4507-4516.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 4507-4516
-
-
Zhang, D.W.1
Graf, G.A.2
Gerard, R.D.3
Cohen, J.C.4
Hobbs, H.H.5
-
13
-
-
1242342236
-
Selective sterol accumulation in ABCG5/ABCG8-deficient mice
-
Yu, L., von Bergmann, K., Lutjohann, D., Hobbs, H. H., and Cohen, J. C. (2004) Selective sterol accumulation in ABCG5/ABCG8-deficient mice. J. Lipid Res. 45, 301-307.
-
(2004)
J. Lipid Res
, vol.45
, pp. 301-307
-
-
Yu, L.1
von Bergmann, K.2
Lutjohann, D.3
Hobbs, H.H.4
Cohen, J.C.5
-
14
-
-
0034717284
-
Newly synthesized canalicular ABC transporters are directly targeted from the Golgi to the hepatocyte apical domain in rat liver
-
Kipp, H., and Arias, I. M. (2000) Newly synthesized canalicular ABC transporters are directly targeted from the Golgi to the hepatocyte apical domain in rat liver. J. Biol. Chem. 275, 15917-15925.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 15917-15925
-
-
Kipp, H.1
Arias, I.M.2
-
15
-
-
0020604269
-
Rat liver canalicular membrane vesicles. Isolation and topological characterization
-
Inoue, M., Kinne, R., Tran, T., Biempica, L., and Arias, I. M. (1983) Rat liver canalicular membrane vesicles. Isolation and topological characterization. J. Biol. Chem. 258, 5183-5188.
-
(1983)
J. Biol. Chem
, vol.258
, pp. 5183-5188
-
-
Inoue, M.1
Kinne, R.2
Tran, T.3
Biempica, L.4
Arias, I.M.5
-
16
-
-
0022978965
-
Isolation and reconstitution of the clathrin-coated vesicle proton translocating complex
-
Xie, X. S., and Stone, D. K. (1986) Isolation and reconstitution of the clathrin-coated vesicle proton translocating complex. J. Biol. Chem. 261, 2492-2495.
-
(1986)
J. Biol. Chem
, vol.261
, pp. 2492-2495
-
-
Xie, X.S.1
Stone, D.K.2
-
17
-
-
0016376199
-
Isolation of rat liver plasma membrane fragments in isotonic sucrose
-
Aronson, N. N., and Touster, O. (1974) Isolation of rat liver plasma membrane fragments in isotonic sucrose. Methods Enzymol. 31, 90-102.
-
(1974)
Methods Enzymol
, vol.31
, pp. 90-102
-
-
Aronson, N.N.1
Touster, O.2
-
18
-
-
0027999333
-
Palmitoylation of luteinizing hormone/human choriogonadotropin receptors in transfected cells. Abolition of palmitoylation by mutation of Cys-621 and Cys-622 residues in the cytoplasmic tail increases ligand-induced internalization of the receptor
-
Kawate, N., and Menon, K. M. (1994) Palmitoylation of luteinizing hormone/human choriogonadotropin receptors in transfected cells. Abolition of palmitoylation by mutation of Cys-621 and Cys-622 residues in the cytoplasmic tail increases ligand-induced internalization of the receptor. J. Biol. Chem. 269, 30651-30658.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 30651-30658
-
-
Kawate, N.1
Menon, K.M.2
-
19
-
-
0027761004
-
WIF-B cells: An in vitro model for studies of hepatocyte polarity
-
Ihrke, G., Neufeld, E. B., Meads, T., Shanks, M. R., Cassio, D., Laurent, M., Schroer, T. A., Pagano, R. E., and Hubbard, A. L. (1993) WIF-B cells: An in vitro model for studies of hepatocyte polarity. J. Cell Biol. 123, 1761-1775.
-
(1993)
J. Cell Biol
, vol.123
, pp. 1761-1775
-
-
Ihrke, G.1
Neufeld, E.B.2
Meads, T.3
Shanks, M.R.4
Cassio, D.5
Laurent, M.6
Schroer, T.A.7
Pagano, R.E.8
Hubbard, A.L.9
-
20
-
-
0033396432
-
Bile acid secretion and direct targeting of mdr1-green fluorescent protein from Golgi to the canalicular membrane in polarized WIF-B cells
-
Sai, Y., Nies, A. T., and Arias, I. M. (1999) Bile acid secretion and direct targeting of mdr1-green fluorescent protein from Golgi to the canalicular membrane in polarized WIF-B cells. J. Cell Sci. 112, 4535-4545.
-
(1999)
J. Cell Sci
, vol.112
, pp. 4535-4545
-
-
Sai, Y.1
Nies, A.T.2
Arias, I.M.3
-
21
-
-
33747469947
-
Purification and ATP hydrolysis of the putative cholesterol transporters ABCG5 and ABCG8
-
Wang, Z., Stalcup, L. D., Harvey, B. J., Weber, J., Chloupkova, M., Dumont, M. E., Dean, M., and Urbatsch, I. L. (2006) Purification and ATP hydrolysis of the putative cholesterol transporters ABCG5 and ABCG8. Biochemistry 45, 9929-9939.
-
(2006)
Biochemistry
, vol.45
, pp. 9929-9939
-
-
Wang, Z.1
Stalcup, L.D.2
Harvey, B.J.3
Weber, J.4
Chloupkova, M.5
Dumont, M.E.6
Dean, M.7
Urbatsch, I.L.8
-
22
-
-
2642573588
-
Missense mutations in ABCG5 and ABCG8 disrupt heterodimerization and trafficking
-
Graf, G. A., Cohen, J. C., and Hobbs, H. H. (2004) Missense mutations in ABCG5 and ABCG8 disrupt heterodimerization and trafficking. J. Biol. Chem. 279, 24881-24888.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 24881-24888
-
-
Graf, G.A.1
Cohen, J.C.2
Hobbs, H.H.3
-
23
-
-
0037073730
-
Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation
-
Ozvegy, C., Varadi, A., and Sarkadi, B. (2002) Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation. J. Biol. Chem. 277, 47980-47990.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 47980-47990
-
-
Ozvegy, C.1
Varadi, A.2
Sarkadi, B.3
-
24
-
-
33744952259
-
Purification and ATPase activity of human ABCA1
-
Takahashi, K., Kimura, Y., Kioka, N., Matsuo, M., and Ueda, K. (2006) Purification and ATPase activity of human ABCA1. J. Biol. Chem. 281, 10760-10768.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 10760-10768
-
-
Takahashi, K.1
Kimura, Y.2
Kioka, N.3
Matsuo, M.4
Ueda, K.5
-
25
-
-
0024263339
-
Chemical identification of cysteine as palmitoylation site in a transmembrane protein (Semliki Forest virus E1)
-
Schmidt, M., Schmidt, M. F., and Rott, R. (1988) Chemical identification of cysteine as palmitoylation site in a transmembrane protein (Semliki Forest virus E1). J. Biol. Chem. 263, 18635-18639.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 18635-18639
-
-
Schmidt, M.1
Schmidt, M.F.2
Rott, R.3
-
26
-
-
35648963623
-
ABC transporters: How small machines do a big job
-
Davidson, A. L., and Maloney, P. C. (2007) ABC transporters: How small machines do a big job. Trends Microbiol. 15, 448-455.
-
(2007)
Trends Microbiol
, vol.15
, pp. 448-455
-
-
Davidson, A.L.1
Maloney, P.C.2
-
27
-
-
0000761427
-
Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease
-
Sun, H., Molday, R. S., and Nathans, J. (1999) Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease. J. Biol. Chem. 274, 8269-8281.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 8269-8281
-
-
Sun, H.1
Molday, R.S.2
Nathans, J.3
-
28
-
-
0034602270
-
Functional reconstitution of substrate transport by purified multidrug resistance protein MRP1 (ABCC1) in phospholipid vesicles
-
Mao, Q., Deeley, R. G., and Cole, S. P. (2000) Functional reconstitution of substrate transport by purified multidrug resistance protein MRP1 (ABCC1) in phospholipid vesicles. J. Biol. Chem. 275, 34166-34172.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 34166-34172
-
-
Mao, Q.1
Deeley, R.G.2
Cole, S.P.3
-
29
-
-
34548853133
-
Structure and mechanism of ABC transporter proteins
-
Hollenstein, K., Dawson, R. J., and Locher, K. P. (2007) Structure and mechanism of ABC transporter proteins. Curr. Opin. Struct. Biol. 17, 412-418.
-
(2007)
Curr. Opin. Struct. Biol
, vol.17
, pp. 412-418
-
-
Hollenstein, K.1
Dawson, R.J.2
Locher, K.P.3
-
30
-
-
2442520293
-
Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2
-
Xu, J., Liu, Y., Yang, Y., Bates, S., and Zhang, J.-T. (2004) Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2. J. Biol. Chem. 279, 19781-19789.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 19781-19789
-
-
Xu, J.1
Liu, Y.2
Yang, Y.3
Bates, S.4
Zhang, J.-T.5
-
31
-
-
33745971403
-
Transition from dimers to higher oligomeric forms occurs during the ATPase cycle of the ABCA1 transporter
-
Trompier, D., Alibert, M., Davanture, S., Hamon, Y., Pierres, M., and Chimini, G. (2006) Transition from dimers to higher oligomeric forms occurs during the ATPase cycle of the ABCA1 transporter. J. Biol. Chem. 281, 20283-20290.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 20283-20290
-
-
Trompier, D.1
Alibert, M.2
Davanture, S.3
Hamon, Y.4
Pierres, M.5
Chimini, G.6
-
32
-
-
33845794047
-
Palmitoylation: Policing protein stability and traffic
-
Linder, M. E., and Deschenes, R. J. (2007) Palmitoylation: Policing protein stability and traffic. Nat. Rev. Mol. Cell. Biol. 8, 74-84.
-
(2007)
Nat. Rev. Mol. Cell. Biol
, vol.8
, pp. 74-84
-
-
Linder, M.E.1
Deschenes, R.J.2
-
33
-
-
10444253304
-
Identification of PSD-95 palmitoylating enzymes
-
Fukata, M., Fukata, Y., Adesnik, H., Nicoll, R. A., and Bredt, D. S. (2004) Identification of PSD-95 palmitoylating enzymes. Neuron 44, 987-996.
-
(2004)
Neuron
, vol.44
, pp. 987-996
-
-
Fukata, M.1
Fukata, Y.2
Adesnik, H.3
Nicoll, R.A.4
Bredt, D.S.5
-
34
-
-
33746587831
-
Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase
-
Fernandez-Hernando, C., Fukata, M., Bernatchez, P. N., Fukata, Y., Lin, M. I., Bredt, D. S., and Sessa, W. C. (2006) Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase. J. Cell Biol. 174, 369-377.
-
(2006)
J. Cell Biol
, vol.174
, pp. 369-377
-
-
Fernandez-Hernando, C.1
Fukata, M.2
Bernatchez, P.N.3
Fukata, Y.4
Lin, M.I.5
Bredt, D.S.6
Sessa, W.C.7
-
35
-
-
3543099503
-
Palmitoylation of intracellular signaling proteins: Regulation and function
-
Smotrys, J. E., and Linder, M. E. (2004) Palmitoylation of intracellular signaling proteins: Regulation and function. Annu. Rev. Biochem. 73, 559-587.
-
(2004)
Annu. Rev. Biochem
, vol.73
, pp. 559-587
-
-
Smotrys, J.E.1
Linder, M.E.2
-
36
-
-
17644422776
-
Characterization of polarized expression of point- or deletion-mutated human BCRP/ABCG2 in LLC-PK1 cells
-
Takada, T., Suzuki, H., and Sugiyama, Y. (2005) Characterization of polarized expression of point- or deletion-mutated human BCRP/ABCG2 in LLC-PK1 cells. Pharm. Res. 22, 458-464.
-
(2005)
Pharm. Res
, vol.22
, pp. 458-464
-
-
Takada, T.1
Suzuki, H.2
Sugiyama, Y.3
-
37
-
-
0037422545
-
Role of ABC transporters in secretion of cholesterol from liver into bile
-
Small, D. M. (2003) Role of ABC transporters in secretion of cholesterol from liver into bile. Proc. Natl. Acad. Sci. U.S.A. 100, 4-6.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 4-6
-
-
Small, D.M.1
-
38
-
-
34548686115
-
The sterol transporting heterodimer ABCG5/ABCG8 requires bile salts to mediate cholesterol efflux
-
Vrins, C., Vink, E., Vandenberghe, K. E., Frijters, R., Seppen, J., and Groen, A. K. (2007) The sterol transporting heterodimer ABCG5/ABCG8 requires bile salts to mediate cholesterol efflux. FEBS Lett. 581, 4616-4620.
-
(2007)
FEBS Lett
, vol.581
, pp. 4616-4620
-
-
Vrins, C.1
Vink, E.2
Vandenberghe, K.E.3
Frijters, R.4
Seppen, J.5
Groen, A.K.6
-
39
-
-
0023665288
-
Self-association of the low density lipoprotein receptor mediated by the cytoplasmic domain
-
van Driel, I. R., Davis, C. G., Goldstein, J. L., and Brown, M. S. (1987) Self-association of the low density lipoprotein receptor mediated by the cytoplasmic domain. J. Biol. Chem. 262, 16127-16134.
-
(1987)
J. Biol. Chem
, vol.262
, pp. 16127-16134
-
-
van Driel, I.R.1
Davis, C.G.2
Goldstein, J.L.3
Brown, M.S.4
|