메뉴 건너뛰기




Volumn 120, Issue 2, 2011, Pages 310-321

Inactivation of YAP1 enhances sensitivity of the yeast RNR3-lacZ genotoxicity testing system to a broad range of DNA-damaging agents

Author keywords

Genotoxicity test; Oxidative compounds; RNR3 lacZ; Sensitivity; YAP1; Yeast

Indexed keywords

REACTIVE OXYGEN METABOLITE;

EID: 79953100097     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq391     Document Type: Article
Times cited : (15)

References (55)
  • 1
    • 0023392267 scopus 로고
    • A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains
    • Alani, E., Cao, L., and Kleckner, N. (1987). A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics 116, 541-545.
    • (1987) Genetics , vol.116 , pp. 541-545
    • Alani, E.1    Cao, L.2    Kleckner, N.3
  • 2
    • 58849161899 scopus 로고    scopus 로고
    • Antioxidant small molecules confer variable protection against oxidative damage in yeast mutants
    • Amari, F., Fettouche, A., Samra, M. A., Kefalas, P., Kampranis, S. C., and Makris, A. M. (2008). Antioxidant small molecules confer variable protection against oxidative damage in yeast mutants. J. Agric. Food Chem. 56, 11740-11751.
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 11740-11751
    • Amari, F.1    Fettouche, A.2    Samra, M.A.3    Kefalas, P.4    Kampranis, S.C.5    Makris, A.M.6
  • 3
    • 0020508747 scopus 로고
    • Dietary carcinogens and anticarcinogens Oxygen radicals and degenerative diseases
    • Ames, B. N. (1983). Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science 221, 1256-1264.
    • (1983) Science , vol.221 , pp. 1256-1264
    • Ames, B.N.1
  • 4
    • 3242715114 scopus 로고    scopus 로고
    • Reactive oxygen species: metabolism, oxidative stress, and signal transduction
    • Apel, K., and Hirt, H. (2004). Reactive oxygen species: metabolism, oxidative stress, and signal transduction. Annu. Rev. Plant Biol. 55, 373-399.
    • (2004) Annu. Rev. Plant Biol. , vol.55 , pp. 373-399
    • Apel, K.1    Hirt, H.2
  • 5
    • 34447253549 scopus 로고    scopus 로고
    • Effects of organosulfurs, isothiocyanates and vitamin C towards hydrogen peroxide-induced oxidative DNA damage (strand breaks and oxidized purines/pyrimidines) in human hepatoma cells
    • Arranz, N., Haza, A. I., Garcia, A., Delgado, E., Rafter, J., and Morales, P. (2007). Effects of organosulfurs, isothiocyanates and vitamin C towards hydrogen peroxide-induced oxidative DNA damage (strand breaks and oxidized purines/pyrimidines) in human hepatoma cells. Chem. Biol. Interact. 169, 63-71.
    • (2007) Chem. Biol. Interact. , vol.169 , pp. 63-71
    • Arranz, N.1    Haza, A.I.2    Garcia, A.3    Delgado, E.4    Rafter, J.5    Morales, P.6
  • 6
    • 0037186889 scopus 로고    scopus 로고
    • Induction of oxidative DNA damage by carcinogenic metals
    • Bal, W., and Kasprzak, K. S. (2002). Induction of oxidative DNA damage by carcinogenic metals. Toxicol. Lett. 127, 55-62.
    • (2002) Toxicol. Lett. , vol.127 , pp. 55-62
    • Bal, W.1    Kasprzak, K.S.2
  • 7
    • 33845735505 scopus 로고    scopus 로고
    • DNA damage checkpoints are involved in postreplication repair
    • Barbour, L., Ball, L. G., Zhang, K., and Xiao, W. (2006). DNA damage checkpoints are involved in postreplication repair. Genetics 174, 1789-1800.
    • (2006) Genetics , vol.174 , pp. 1789-1800
    • Barbour, L.1    Ball, L.G.2    Zhang, K.3    Xiao, W.4
  • 8
    • 50949122899 scopus 로고    scopus 로고
    • Efficacy of antioxidants in the yeast Saccharomyces cerevisiae correlates with their effects on protein thiols
    • Bednarska, S., Leroy, P., Zagulski, M., and Bartosz, G. (2008). Efficacy of antioxidants in the yeast Saccharomyces cerevisiae correlates with their effects on protein thiols. Biochimie 90, 1476-1485.
    • (2008) Biochimie , vol.90 , pp. 1476-1485
    • Bednarska, S.1    Leroy, P.2    Zagulski, M.3    Bartosz, G.4
  • 9
    • 0021668558 scopus 로고
    • A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance
    • Boeke, J. D., LaCroute, F., and Fink, G. R. (1984). A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197, 345-346.
    • (1984) Mol. Gen. Genet. , vol.197 , pp. 345-346
    • Boeke, J.D.1    LaCroute, F.2    Fink, G.R.3
  • 12
    • 47849100494 scopus 로고    scopus 로고
    • Mechanism of oxidative DNA damage repair and relevance to human pathology
    • D'Errico, M., Parlanti, E., and Dogliotti, E. (2008). Mechanism of oxidative DNA damage repair and relevance to human pathology. Mutat. Res. Rev. Mutat. Res. 659, 4-14.
    • (2008) Mutat. Res. Rev. Mutat. Res. , vol.659 , pp. 4-14
    • D'Errico, M.1    Parlanti, E.2    Dogliotti, E.3
  • 13
    • 0034069998 scopus 로고    scopus 로고
    • A large-scale study of Yap1p-dependent genes in normal aerobic and H2O2-stress conditions: the role of Yap1p in cell proliferation control in yeast
    • Dumond, H., Danielou, N., Pinto, M., and Bolotin-Fukuhara, M. (2000). A large-scale study of Yap1p-dependent genes in normal aerobic and H2O2-stress conditions: the role of Yap1p in cell proliferation control in yeast. Mol. Microbiol. 36, 830-845.
    • (2000) Mol. Microbiol. , vol.36 , pp. 830-845
    • Dumond, H.1    Danielou, N.2    Pinto, M.3    Bolotin-Fukuhara, M.4
  • 14
    • 0042827232 scopus 로고    scopus 로고
    • Free radical scavenging abilities of flavonoids as mechanism of protection against mutagenicity induced by tertbutyl hydroperoxide or cumene hydroperoxide in Salmonella typhimurium TA102
    • Edenharder, R., and Grunhage, D. (2003). Free radical scavenging abilities of flavonoids as mechanism of protection against mutagenicity induced by tertbutyl hydroperoxide or cumene hydroperoxide in Salmonella typhimurium TA102. Mutat. Res. 540, 1-18.
    • (2003) Mutat. Res. , vol.540 , pp. 1-18
    • Edenharder, R.1    Grunhage, D.2
  • 15
    • 0024427565 scopus 로고
    • Induction of sfiA SOS function by peroxides using three different E. coli strains
    • Eder, E., Favre, A., Stichtmann, C., and Deininger, C. (1989). Induction of sfiA SOS function by peroxides using three different E. coli strains. Toxicol. Lett. 48, 225-234.
    • (1989) Toxicol. Lett. , vol.48 , pp. 225-234
    • Eder, E.1    Favre, A.2    Stichtmann, C.3    Deininger, C.4
  • 16
    • 0024239038 scopus 로고
    • Antioxidant defenses and lipid peroxidation in human blood plasma
    • Frei, B., Stocker, R., and Ames, B. N. (1988). Antioxidant defenses and lipid peroxidation in human blood plasma. Proc. Natl. Acad. Sci. U.S.A. 85, 9748-9752.
    • (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , pp. 9748-9752
    • Frei, B.1    Stocker, R.2    Ames, B.N.3
  • 18
    • 0031463790 scopus 로고    scopus 로고
    • Repair of oxidized DNA bases in the yeast Saccharomyces cerevisiae
    • Girard, P. M., and Boiteux, S. (1997). Repair of oxidized DNA bases in the yeast Saccharomyces cerevisiae. Biochimie 79, 559-566.
    • (1997) Biochimie , vol.79 , pp. 559-566
    • Girard, P.M.1    Boiteux, S.2
  • 19
    • 0020645052 scopus 로고
    • Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast
    • Guarente, L. (1983). Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol. 101, 181-191.
    • (1983) Methods Enzymol , vol.101 , pp. 181-191
    • Guarente, L.1
  • 20
    • 0021926563 scopus 로고
    • Identification and mapping of regions of the plasmid pKM101 which influence the growth rate and resistance to phleomycin E of escherichia coli WP2
    • Hall, R. M. (1985). Identification and mapping of regions of the plasmid pKM101 which influence the growth rate and resistance to phleomycin E of escherichia coli WP2. J. Bacteriol. 163, 1142-1146.
    • (1985) J. Bacteriol. , vol.163 , pp. 1142-1146
    • Hall, R.M.1
  • 21
    • 33846322528 scopus 로고    scopus 로고
    • 4-NQO induces apoptosis via p53-dependent mitochondrial signaling pathway
    • Han, H., Pan, Q., Zhang, B., Li, J., Deng, X., Lian, Z., and Li, N. (2007). 4-NQO induces apoptosis via p53-dependent mitochondrial signaling pathway. Toxicology 230, 151-163.
    • (2007) Toxicology , vol.230 , pp. 151-163
    • Han, H.1    Pan, Q.2    Zhang, B.3    Li, J.4    Deng, X.5    Lian, Z.6    Li, N.7
  • 22
    • 77957219655 scopus 로고
    • DMSO-enhanced whole cell yeast transformation
    • Hill, J., Donald, K. A., and Griffiths, D. E. (1991). DMSO-enhanced whole cell yeast transformation. Nucleic Acids Res. 19, 5791.
    • (1991) Nucleic Acids Res , vol.19 , pp. 5791
    • Hill, J.1    Donald, K.A.2    Griffiths, D.E.3
  • 23
    • 0141482059 scopus 로고    scopus 로고
    • A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations
    • Huang, M. E., Rio, A. G., Nicolas, A., and Kolodner, R. D. (2003). A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc. Natl. Acad. Sci. U.S.A. 100, 11529-11534.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 11529-11534
    • Huang, M.E.1    Rio, A.G.2    Nicolas, A.3    Kolodner, R.D.4
  • 24
    • 0032439653 scopus 로고    scopus 로고
    • Oxidative stress responses of the yeast Saccharomyces cerevisiae
    • Jamieson, D. J. (1998). Oxidative stress responses of the yeast Saccharomyces cerevisiae. Yeast 14, 1511-1527.
    • (1998) Yeast , vol.14 , pp. 1511-1527
    • Jamieson, D.J.1
  • 25
    • 0042382945 scopus 로고    scopus 로고
    • Compromised DNA repair enhances sensitivity of the yeast RNR3-lacZ genotoxicity testing system
    • Jia, X., and Xiao, W. (2003). Compromised DNA repair enhances sensitivity of the yeast RNR3-lacZ genotoxicity testing system. Toxicol. Sci. 75, 82-88.
    • (2003) Toxicol. Sci. , vol.75 , pp. 82-88
    • Jia, X.1    Xiao, W.2
  • 26
    • 75249092372 scopus 로고    scopus 로고
    • Assessing DNA damage using a reporter gene system
    • (Z. Yan and G. W. Caldwell, Eds.), The Humana Press, Totowa NJ
    • Jia, X., and Xiao, W. (2004). Assessing DNA damage using a reporter gene system. In Optimization in Drug Discovery: In Vitro Methods. (Z. Yan and G. W. Caldwell, Eds.), pp. 315-323. The Humana Press, Totowa, NJ.
    • (2004) Optimization in Drug Discovery: In Vitro Methods , pp. 315-323
    • Jia, X.1    Xiao, W.2
  • 27
    • 0037179175 scopus 로고    scopus 로고
    • A stable and sensitive genotoxic testing system based on DNA damage induced gene expression in Saccharomyces cerevisiae
    • Jia, X., Zhu, Y., and Xiao, W. (2002). A stable and sensitive genotoxic testing system based on DNA damage induced gene expression in Saccharomyces cerevisiae. Mutat. Res. 519, 83-92.
    • (2002) Mutat. Res. , vol.519 , pp. 83-92
    • Jia, X.1    Zhu, Y.2    Xiao, W.3
  • 28
    • 20344404721 scopus 로고    scopus 로고
    • Cytotoxic and genotoxic effects of tert-butyl hydroperoxide on Chinese hamster B14 cells
    • Lapshina, E. A., Zavodnik, I. B., Labieniec, M., Rekawiecka, K., and Bryszewska, M. (2005). Cytotoxic and genotoxic effects of tert-butyl hydroperoxide on Chinese hamster B14 cells. Mutat. Res. 583, 189-197.
    • (2005) Mutat. Res. , vol.583 , pp. 189-197
    • Lapshina, E.A.1    Zavodnik, I.B.2    Labieniec, M.3    Rekawiecka, K.4    Bryszewska, M.5
  • 29
    • 34147143424 scopus 로고    scopus 로고
    • Cytoplasmic glutathione redox status determines survival upon exposure to the thiol-oxidant 4 4'-dipyridyl disulfide
    • Lopez-Mirabal, H. R., Thorsen, M., Kielland-Brandt, M. C., Toledano, M. B., and Winther, J. R. (2007). Cytoplasmic glutathione redox status determines survival upon exposure to the thiol-oxidant 4,4'-dipyridyl disulfide. FEMS Yeast Res. 7, 391-403.
    • (2007) FEMS Yeast Res , vol.7 , pp. 391-403
    • Lopez-Mirabal, H.R.1    Thorsen, M.2    Kielland-Brandt, M.C.3    Toledano, M.B.4    Winther, J.R.5
  • 30
    • 0031719952 scopus 로고    scopus 로고
    • The yeast Saccharomyces cerevisiae contains two glutaredoxin genes that are required for protection against reactive oxygen species
    • Luikenhuis, S., Perrone, G., Dawes, I. W., and Grant, C. M. (1998). The yeast Saccharomyces cerevisiae contains two glutaredoxin genes that are required for protection against reactive oxygen species. Mol. Biol. Cell 9, 1081-1091.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 1081-1091
    • Luikenhuis, S.1    Perrone, G.2    Dawes, I.W.3    Grant, C.M.4
  • 31
    • 0029990930 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae IMP2 gene encodes a transcriptional activator that mediates protection against DNA damage caused by bleomycin and other oxidants
    • Masson, J. Y., and Ramotar, D. (1996). The Saccharomyces cerevisiae IMP2 gene encodes a transcriptional activator that mediates protection against DNA damage caused by bleomycin and other oxidants. Mol. Cell Biol. 16, 2091-2100.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 2091-2100
    • Masson, J.Y.1    Ramotar, D.2
  • 32
    • 0141905895 scopus 로고    scopus 로고
    • Characterization of AP lyase activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: implications for biological function
    • Meadows, K. L., Song, B., and Doetsch, P. W. (2003). Characterization of AP lyase activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: implications for biological function. Nucleic Acids Res. 31, 5560-5567.
    • (2003) Nucleic Acids Res , vol.31 , pp. 5560-5567
    • Meadows, K.L.1    Song, B.2    Doetsch, P.W.3
  • 34
    • 0036199670 scopus 로고    scopus 로고
    • Transcription factors regulating the response to oxidative stress in yeast
    • Moye-Rowley, W. S. (2002). Transcription factors regulating the response to oxidative stress in yeast. Antioxid. Redox Signal. 4, 123-140.
    • (2002) Antioxid. Redox Signal. , vol.4 , pp. 123-140
    • Moye-Rowley, W.S.1
  • 35
    • 0024638464 scopus 로고
    • Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins
    • Moye-Rowley, W. S., Harshman, K. D., and Parker, C. S. (1989). Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins. Genes Dev. 3, 283-292.
    • (1989) Genes Dev , vol.3 , pp. 283-292
    • Moye-Rowley, W.S.1    Harshman, K.D.2    Parker, C.S.3
  • 36
    • 0035963338 scopus 로고    scopus 로고
    • Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae
    • Myung, K., Chen, C., and Kolodner, R. D. (2001). Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae. Nature 411, 1073-1076.
    • (2001) Nature , vol.411 , pp. 1073-1076
    • Myung, K.1    Chen, C.2    Kolodner, R.D.3
  • 38
    • 53049083570 scopus 로고    scopus 로고
    • DNA damageinduced reactive oxygen species (ROS) stress response in Saccharomyces cerevisiae
    • Rowe, L. A., Degtyareva, N., and Doetsch, P. W. (2008). DNA damageinduced reactive oxygen species (ROS) stress response in Saccharomyces cerevisiae. Free Radic. Biol. Med. 45, 1167-1177.
    • (2008) Free Radic. Biol. Med. , vol.45 , pp. 1167-1177
    • Rowe, L.A.1    Degtyareva, N.2    Doetsch, P.W.3
  • 39
    • 33749024433 scopus 로고    scopus 로고
    • Antioxidant activity of L-ascorbic acid in wild-type and superoxide dismutase deficient strains of Saccharomyces cerevisiae
    • Saffi, J., Sonego, L., Varela, Q. D., and Salvador, M. (2006). Antioxidant activity of L-ascorbic acid in wild-type and superoxide dismutase deficient strains of Saccharomyces cerevisiae. Redox Rep. 11, 179-184.
    • (2006) Redox Rep , vol.11 , pp. 179-184
    • Saffi, J.1    Sonego, L.2    Varela, Q.D.3    Salvador, M.4
  • 40
    • 3142707088 scopus 로고    scopus 로고
    • Biological consequences of oxidative stress-induced DNA damage in Saccharomyces cerevisiae
    • Salmon, T. B., Evert, B. A., Song, B., and Doetsch, P. W. (2004). Biological consequences of oxidative stress-induced DNA damage in Saccharomyces cerevisiae. Nucleic Acids Res. 32, 3712-3723.
    • (2004) Nucleic Acids Res , vol.32 , pp. 3712-3723
    • Salmon, T.B.1    Evert, B.A.2    Song, B.3    Doetsch, P.W.4
  • 41
    • 0026560388 scopus 로고
    • The PAR1 (YAP1/SNQ3) gene of Saccharomyces cerevisiae, a c-jun homologue, is involved in oxygen metabolism
    • Schnell, N., Krems, B., and Entian, K. D. (1992). The PAR1 (YAP1/SNQ3) gene of Saccharomyces cerevisiae, a c-jun homologue, is involved in oxygen metabolism. Curr. Genet. 21, 269-273.
    • (1992) Curr. Genet. , vol.21 , pp. 269-273
    • Schnell, N.1    Krems, B.2    Entian, K.D.3
  • 43
    • 20444415235 scopus 로고    scopus 로고
    • Complex cellular responses to reactive oxygen species
    • Temple, M. D., Perrone, G. G., and Dawes, I. W. (2005). Complex cellular responses to reactive oxygen species. Trends Cell Biol. 15, 319-326.
    • (2005) Trends Cell Biol , vol.15 , pp. 319-326
    • Temple, M.D.1    Perrone, G.G.2    Dawes, I.W.3
  • 44
    • 0030929349 scopus 로고    scopus 로고
    • Inactivation of OGG1 increases the incidence of G C->T. A transversions in Saccharomyces cerevisiae: evidence for endogenous oxidative damage to DNA in eukaryotic cells
    • Thomas, D., Scot, A. D., Barbey, R., Padula, M., and Boiteux, S. (1997). Inactivation of OGG1 increases the incidence of G. C->T. A transversions in Saccharomyces cerevisiae: evidence for endogenous oxidative damage to DNA in eukaryotic cells. Mol. Gen. Genet. 254, 171-178.
    • (1997) Mol. Gen. Genet. , vol.254 , pp. 171-178
    • Thomas, D.1    Scot, A.D.2    Barbey, R.3    Padula, M.4    Boiteux, S.5
  • 45
    • 2342487990 scopus 로고    scopus 로고
    • Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes
    • Thorpe, G. W., Fong, C. S., Alic, N., Higgins, V. J., and Dawes, I. W. (2004). Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc. Natl. Acad. Sci. U.S.A. 101, 6564-6569.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 6564-6569
    • Thorpe, G.W.1    Fong, C.S.2    Alic, N.3    Higgins, V.J.4    Dawes, I.W.5
  • 46
    • 0034746231 scopus 로고    scopus 로고
    • 3'-phosphodiesterase and 3'->5' exonuclease activities of yeast Apn2 protein and requirement of these activities for repair of oxidative DNA damage
    • Unk, I., Haracska, L., Prakash, S., and Prakash, L. (2001). 3'-phosphodiesterase and 3'->5' exonuclease activities of yeast Apn2 protein and requirement of these activities for repair of oxidative DNA damage. Mol. Cell Biol. 21, 1656-1661.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 1656-1661
    • Unk, I.1    Haracska, L.2    Prakash, S.3    Prakash, L.4
  • 48
    • 24044548688 scopus 로고    scopus 로고
    • Genetic modification and variations in solvent increase the sensitivity of the yeast RAD54-GFP genotoxicity assay
    • Walsh, L., Hastwell, P. W., Keenan, P. O., Knight, A. W., Billinton, N., and Walmsley, R. M. (2005). Genetic modification and variations in solvent increase the sensitivity of the yeast RAD54-GFP genotoxicity assay. Mutagenesis 20, 317-327.
    • (2005) Mutagenesis , vol.20 , pp. 317-327
    • Walsh, L.1    Hastwell, P.W.2    Keenan, P.O.3    Knight, A.W.4    Billinton, N.5    Walmsley, R.M.6
  • 49
    • 0028241895 scopus 로고
    • Transcriptional activation mediated by the yeast AP-1 protein is required for normal cadmium tolerance
    • Wemmie, J. A., Wu, A. L., Harshman, K. D., Parker, C. S., and Moye-Rowley, W. S. (1994). Transcriptional activation mediated by the yeast AP-1 protein is required for normal cadmium tolerance. J. Biol. Chem. 269, 14690-14697.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14690-14697
    • Wemmie, J.A.1    Wu, A.L.2    Harshman, K.D.3    Parker, C.S.4    Moye-Rowley, W.S.5
  • 50
    • 0030049032 scopus 로고    scopus 로고
    • Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer
    • Wiseman, H., and Halliwell, B. (1996). Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem. J. 313(Pt 1), 17-29.
    • (1996) Biochem. J. , vol.313 , Issue.PART 1 , pp. 17-29
    • Wiseman, H.1    Halliwell, B.2
  • 51
    • 0027359370 scopus 로고
    • A common element involved in transcriptional regulation of two DNA alkylation repair genes (MAG and MGT1) of Saccharomyces cerevisiae
    • Xiao, W., Singh, K. K., Chen, B., and Samson, L. (1993). A common element involved in transcriptional regulation of two DNA alkylation repair genes (MAG and MGT1) of Saccharomyces cerevisiae. Mol. Cell Biol. 13, 7213-7221.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 7213-7221
    • Xiao, W.1    Singh, K.K.2    Chen, B.3    Samson, L.4
  • 52
    • 0022458072 scopus 로고
    • Mutagenic and cytotoxic effects of oxygen free radicals generated by methylviologen (paraquat) on Escherichia coli with different DNA-repair capacities
    • Yonei, S., Noda, A., Tachibana, A., and Akasaka, S. (1986). Mutagenic and cytotoxic effects of oxygen free radicals generated by methylviologen (paraquat) on Escherichia coli with different DNA-repair capacities. Mutat. Res. 163, 15-22.
    • (1986) Mutat. Res. , vol.163 , pp. 15-22
    • Yonei, S.1    Noda, A.2    Tachibana, A.3    Akasaka, S.4
  • 53
    • 75249106629 scopus 로고    scopus 로고
    • Creation of a hyperpermeable yeast strain to genotoxic agents through combined inactivation of PDR and CWP genes
    • Zhang, M., Hanna, M., Li, J., Butcher, S., Dai, H., and Xiao, W. (2010). Creation of a hyperpermeable yeast strain to genotoxic agents through combined inactivation of PDR and CWP genes. Toxicol. Sci. 113, 401-411.
    • (2010) Toxicol. Sci. , vol.113 , pp. 401-411
    • Zhang, M.1    Hanna, M.2    Li, J.3    Butcher, S.4    Dai, H.5    Xiao, W.6
  • 54
    • 42149106156 scopus 로고    scopus 로고
    • Deletion of yeast CWP genes enhances cell permeability to genotoxic agents
    • Zhang, M., Liang, Y., Zhang, X., Xu, Y., Dai, H., and Xiao, W. (2008). Deletion of yeast CWP genes enhances cell permeability to genotoxic agents. Toxicol. Sci. 103, 68-76.
    • (2008) Toxicol. Sci. , vol.103 , pp. 68-76
    • Zhang, M.1    Liang, Y.2    Zhang, X.3    Xu, Y.4    Dai, H.5    Xiao, W.6
  • 55
    • 0026651652 scopus 로고
    • Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae
    • Zhou, Z., and Elledge, S. J. (1992). Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae. Genetics 131, 851-866.
    • (1992) Genetics , vol.131 , pp. 851-866
    • Zhou, Z.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.