Creation of a hyperpermeable yeast strain to genotoxic agents through combined inactivation of PDR and CWP genes

Toxicological Sciences

Volumn 113, Issue 2, 2009, Pages 401-411

  Zhang, Min ^a   Hanna, Michelle ^b   Li, Jia ^b   Butcher, Susan ^b   Dai, Heping ^a   Xiao, Wei ^b  

^a INSTITUTE OF HYDROBIOLOGY   (China)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

ABC transporters; Cell wall; Genotoxicity test; Permeability; RNR3 lacZ; Saccharomyces cerevisiae

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; BETA GALACTOSIDASE; CARRIER PROTEIN; CELL WALL MANNOPROTEIN; CHLORAMBUCIL; CISPLATIN; FUNGAL DNA; FUNGAL PROTEIN; MESYLIC ACID METHYL ESTER; PHLEOMYCIN; PLEIOTROPHIC DRUG RESISTANCE PROTEIN; UNCLASSIFIED DRUG;

AMES TEST; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL PROTECTION; CHEMOSENSITIVITY; CONTROLLED STUDY; DNA DAMAGE; FUNGAL STRAIN; GENE DELETION; GENE INACTIVATION; GENE MUTATION; GENOTOXICITY; NONHUMAN; PROTEIN FUNCTION; REPORTER GENE; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

ANTICARCINOGENIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CELL MEMBRANE PERMEABILITY; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GENE SILENCING; LAC OPERON; MEMBRANE GLYCOPROTEINS; MUTAGENICITY TESTS; MUTAGENS; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTIONAL ACTIVATION;

SACCHAROMYCES CEREVISIAE;

EID: 75249106629     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp267     Document Type: Article

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